• Journal of the korean academy of Pediatric Dentistry
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• v.33 no.4
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• pp.699-703
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• 2006

The purpose of this study was to analyze the parental consultations, patients' age and consulters. Also it was to improve the tendency of consultation homepage The subjects were 2485 questions on Korean Academy of Pediatric Dentistry Homepage except deleted questions which were not related with consultations. The examined contents were categorized into patients' age, counseling contents, consulters. The results were as follows: 1. Patients mostly belonged to preschool children(64.29%). 2. In the subjects, questions were mostly about growth and development, restorative and pulp treatment. 3. In the subdivided subjects, great part of questions were about tooth eruption, restorative and pulp treatment and trauma. 4. The 93.72% of consulters were mothers. 5. We should reinforce with FAQ about growth and development, restorative and pulp treatment and trauma. Also we should improve on quality of information and childcare related contents and Homepage related pediatric dentistry.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.10
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• pp.227-236
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• 2017

This study attempted to develop and investigate the effects of hair-nourishing cosmetics containing saponin astragaloside from Astragalus membranaceus Bunge on eyebrow growth and development for eventual product development. For this, current use of hair nutrients was investigated in general consumers through a questionnaire survey. A test was conducted for 6 weeks against the same subjects divided into two groups: experimental group with 0.5% saponin astragaloside on the right eyebrow and control group without any astragaloside on the left eyebrow. The results were as follows. In the control group, no significant changes were found in terms of eyebrow length and thickness. In the experimental group with 0.5% saponin astragaloside added, eyebrow length, root, and thickness of the middle area considerably increased. In other words, saponin astragaloside was confirmed an effective natural substance. In addition, subjective assessments such as usability, marketability, and satisfaction assessments supported the usability and market value of saponin astragaloside. Such results reveal that hair-nourishing cosmetics containing saponin astragaloside from Astragalus membranaceus Bunge would be helpful in improving and maintaining eyebrow growth for those concerned about loss and shortening of their eyebrows, showing the potential of product development.

• Korean journal of applied entomology
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• v.36 no.4
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• pp.317-322
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• 1997

Hatched-larvae of the mulberry longicorn beetle, Apriona germari Hope, collected from mulberry fields were reared on artificial diet at 25$^{\circ}$C with 14 h light and 10 h dark to study the larval developmental characteristics. Artificial diet developed for rearing silkworm was used with minor modification adding mulberry branch powder. In case of artificial diet rearing, the head width of larval instar from the I st to the 12th instars was ranged from 0.12 to 0.69cm, and growth rate of each instar was significantly high between the I st and the 2nd instars. In addition, the weight of the 8th instar larvae was increased approximately 176-fold in comparision with that of the 1st instar larvae. Larval duration of each instar took long with larval developmental stages, and that of the 1st to the 9th or the 12th instars was 186.03 or 304.58 days, respectively. The survival rate of larvae was 40.8% by the 8th instar. The pupation rate was approximately 32.4%. Furthermore, although pupation stage was broadly appeared from the 7th to the I lth instars, pupation was majorly observed at the 8th and the 9th instars.

• Journal of the korean academy of Pediatric Dentistry
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• v.37 no.4
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• pp.505-511
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• 2010

Odontoma represents 22% of all odontogenic tumors, which is characterized by slow growth pattern. Most of the odontomas usually develop during dental follicle proliferation. The growth of odontoma is limited and lesion is generally asymptomatic. It is frequently diagnosed during assessments for delayed eruption of permanent tooth and is usually founded in the second decade of life. Odontoma is usually diagnosed through radiographic views and is difficult to diagnose at the early developmental stage of odontoma. But an uncalcified developing odontoma can disturb the eruption of the tooth, so it is important to perform periodic radiographic examinations. Treatments are surgical removal and observation of odontoma followed by surgical opening or orthodontic traction of impacted tooth according to the tooth development and the location of impacted tooth. In this case, we found the radiopaque calcified odontoma in the radiographic view meanwhile follow up of the impacted tooth showing idiopathic eruption disturbance. This suggests that a developing odontoma is the cause of eruption disturbace.

• Parasites, Hosts and Diseases
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• v.27 no.1
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• pp.47-56
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• 1989

Some biological characteristics of Centrecestus armatui were studied using albino rats as its experimental host. The metacercariae were collected from Zacco Platypus by artificial digestion method. Laboratory rats(Wistar) were fed each 100 or 200 metacercariae and sacrificed on 1, 2, 3, 4, 5, 6, 8, 14 and 28 days after infection to recover worms of various ages. The average recovery rate was 10.7% from 82 rats. The rate decreased rather slowly for the first 8 days but showed a steep decrease thereafter. Of the worms, 35.5% were recovered from the duodenum and 62.5% from the jejunum. At metacercarial stage, body length was $293{\mu\textrm{m}}$ and body width $144{\mu\textrm{m}}$. At adult stage, the length and width reached $382{\mu\textrm{m}}$ and $214{\mu\textrm{m}}$ respectively at 14 days after infection. The testes and Mehlis' gland were recognized at metacercarial stage, whereas the ovarian anlage appeared on the 1st day of infection, seminal vesicle and vitellaria on the 2nd day, and seminal receptacle and uterine eggs on the 3rd day. Until 8 days after infection the genital organs developed continuously and the number of uterine eggs increased. The above results show that albino rats are one of useful experimental hosts for C. armatus and the worms can develop to adults in 3 days after infection.

• Journal of the korean academy of Pediatric Dentistry
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• v.30 no.3
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• pp.391-405
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• 2003

Craniosynostosis, known as a premature fusion of cranial sutures, is a developmental disorder characterized by precocious differentiation and mineralization of osteoblasts in the calvarial sutures. Recent genetic studies have demonstrated that mutation in the homeobox gene Msx2 causes Boston-type human craniosynostosis. Additionally, the phenotype of Dlx5 homozygote mutant mouse presents craniofacial abnormalities including a delayed ossification of calvarial bone. Furthermore transcription of osteocalcin, a mature osteoblast marker, is reciprocally regulated by the homeodomain proteins Msx2 and Dlx5. These facts suggest important roles of osteocalcin, Msx2 and Dlx5 genes in the calvarial bone growth and suture morphogenesis. To elucidate the function of these molecules in the early morphogenesis of mouse cranial sutures, we have first analyzed by in situ hybridization the expression of osteocalcin, Msx2 and Dlx5 genes in the developing parietal bone and sagittal suture of mouse calvaria during the embryonic (E15-E18) stage. Osteocalcin mRNA was found in the periosteum of parietal bones from E15, and gradually more highly expressed with aging. Msx2 mRNA was intensely expressed in the sutural mesenchyme, osteogenic fronts and mildly expressed in the dura mater during the embryonic stage. Dlx5 mRNA was intensely expressed osteogenic fronts and the periostem of parietal bones. To further examine the upstream signaling molecules of transcription factor Msx2 and Dlx5, we have done in vitro experiments in E15.5 mouse calvarial explants. Interestingly, implantation of BMP2-, BMP4-soaked beads onto the osteogenic fronts after 48 hours organ culture induced etopic expressions of Msx2 and Dlx5 genes. On the other hand, overexpression of $TGF{\beta}1$, GDF-6, -7, FGF-2, -4 and Shh did not induce the expression of Msx2 and Dlx5. Taken together. these data indicate that transcription factor Msx2 and Dlx5 play critical roles in the calvarial bone and suture development, and that BMP siganling is involved in the osteogenesis of calvarial bones and the maintenance of cranial sutures through regulating these two transcriotpn factors. Furthermore, different expression patterns between Msx2 and Dlx5 suggest their specific functions in the osteoblast differentiation.

• Journal of Sericultural and Entomological Science
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• v.27 no.1
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• pp.1-11
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• 1985

In order to clarify the taxanomic position of a new microsporidia K79 which was isolated from the silkworm larvae, Bombyx mori L. in Korea in 1979, the following several experiments such as estimation of pathogenicity in different instar, histopathological examination under light and electronic microscope and examination of fine structure of the sporse were carried out and their result obtained are as follows. In the test of pathogenicity by oral inoculation, the new microsporidia K79 was lower than Nosema bombycis and the susceptibility of the new microsporidia to silkworm was getting lower as the silkworm larvae grew. The lesion of Silkworms' tissue which was infected with the new microsporidia K79 was found in the epithelial cells of trachea, fat body and silk gland cells. The developmental process of the new microsporidia K79 in vivo could be divided into the following five stages: sporoplasm, schizont, sporont, sporoblast, and spore. The process was just the same as the of N. bombycis, but its development was slower than that of N. bombycis. Several differences in the fine structure of the spore under electron microscope, which could be important keys for the classification of microsporidia, were obtained. Anchoring disk and polaroplast lamella of the new microsporidian spore were disclosed to be different from those of N. bombycis. An average number of polar filament coils of the new microporidian spore was 16 at an angle of 75$^{\circ}$. On the basis of various keys for the classification of microsporidia, the results obtained from various experiments proved that the newly isolated microsporidia should be classified into the Genus, "Nosema", nut is further classification for species should be conducted in the future. Therefore, it may be reasonable that the new microsporidia is temperally classified as Nosema sp. K79 considering the fact that it was discovered in Korea in 1979.a in 1979.

• Korean journal of applied entomology
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• v.42 no.1
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• pp.53-56
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• 2003

Development and reproduction of the rice armyworm, Pseudaletia separata Walker, were investigated under different temperatures (13, 15, 18, 20, 25, 30, and 33$^{\circ}C$ ). It took 80.6 days to grow from egg to pre-adult at 15$^{\circ}C$, and 27.3 days at 30$^{\circ}C$ (3.0 times shorter growth period compared with that at 30$^{\circ}C$ ). The range of developmental temperature of rice armywom was 15-30$^{\circ}C$. Survival rate from hatched larva to pre-adult was the highest as 70.6% at 25$^{\circ}C$. Pre-oviposition period and the adult longevity were 4.2 and 12.3 days at 15$^{\circ}C$, and 2.9 and 8.0 days at 30$^{\circ}C$, respectively. The highest average fecundity per female was 816.6 at 25$^{\circ}C$. The net reproductive rate (R$\_$o/) and intrinsic rate of natural increase (r$\_$m/) were the highest at 25$^{\circ}C$ as 913.0 and 0.175, respectively. As a result, it was considered that optimum of temperature for P. separata growth was = 25.0$^{\circ}C$.

• Parasites, Hosts and Diseases
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• v.22 no.2
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• pp.181-189
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• 1984

The metacercariae of Echinostoma cineterchis (Trematoda: Echinostomatidae) were found infected in the loaches (Misgurnus anguillicaudatus) purchased from two local markets in Korea. Identification of the metacercariae was done after obtaining adult worms from experimentally infected albino rats. Brief course of worm development in rats was also observed up to 28th post-infection day. The results are as follows: 1. The metacercariae of E. cinetorchis were detected from 5 (10.9%) out of 46 loaches examined and the average metacercarial burden per infected loach was 34.4. They were always found from the posterior abdominal wall. 2. The worm recovery rate from 8 rats was 24.6% in average. It was observed that the rate decreased according to age of infection; from 40.7% after 6 days to 15.0% after 28 days. 3. The adult worms were morphologically characterized by the presence of head crown with derfally uninterrupted collar spines, 37-38 in number, and the tendency of migration or disappearance of testes. So that they were identified as Echinostoma cinetorchis Ando et Ozaki, 1923. 4. The development of worm was very rapid during 6-10 days after infection and became much slower thereafter. During the rapid worm growth the development of genital organs was more prominent than that of non-genital organs. From the results it is concluded that the loach is involved in the life cycle of E. cinetorchis in this country and may take a role for infection source to animals and man. It is also confirmed that migration or loss of testes is the distinct specific character of this echinostomatid fluke.

• The korean journal of orthodontics
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• v.39 no.1
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• pp.28-35
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• 2009

Objective: The purpose of this study was to investigate the relationship between menarche and cervical vertebral maturation. Methods: Lateral cephalograms of 67 young korean girls within the range of 1 year before or after their menarche were gathered. The concavity of the cervical vertebrae base and the ratio of the base length to the 3rd and 4th cervical vertebrae anterior height were measured and analyzed. Results: The mean measured values were as follows, concavity of the 3rd cervical vertebrae base: 1.27(${\pm}0.18$) mm, concavity of the 4th cervical vertebrae base: 1.06(${\pm}0.15$) mm, ratio of the base length to the 3rd cervical vertebrae anterior height: 0.73(${\pm}0.06$) and ratio of the base length to the 4th cervical vertebrae anterior height: 0.70(${\pm}0.05$). There was a significant increase in the ratio of the base length to the 3rd vertebrae anterior height and the base concavity of the 3rd and 4th cervical vertebrae during the period of 1 year before to 1 year after their menarche. Conclusions: These characteristics of the 3rd and 4th cervical vertebrae on the lateral cephalogram can provide useful clues on evaluating the growth stage.