• Title/Summary/Keyword: 선형 프로브

Search Result 26, Processing Time 0.023 seconds

카본나노튜브 AFM의 비접촉측정에 관한 연구

  • ;;;;Mark Strus;Arvind Raman
    • Proceedings of the Korean Society of Precision Engineering Conference
    • /
    • 2004.05a
    • /
    • pp.132-132
    • /
    • 2004
  • 카본나노튜브는 나노튜브의 종류에 따라 1~10nm의 직경과 수 $\mu\textrm{m}$정도의 길이를 가지는 고종횡비(high aspect ratio)가 가능하며, 고강성, 전기화학적 내성, 마모에 대한 강인성 때문에 원자력간 현미경(AEM)의 프로브로서 이상적인 재료로 인식되어 왔다. 따라서 단백질이나 DNA를 측정하는 바이오 분야, 나노 일렉트로닉스 분야, 나노 구조 측정분야 등 나노 관련 측정분야에서 점차 그 활용도가 높아 져가고 있다. 특히 100nm이하의 반도체의 CD(critical Dimension)을 측정하는데 있어서 나노튜브는 가장 이상적인 후보라고 할 수 있겠다.(중략)

  • PDF

Development of a Nuclease Protection Assay With Sandwich Hybridization (NPA-SH) to Monitor Heterosigma akashiwo (Heterosigma akashiwo를 모니터하기 위한 뉴클레아제 보호 분석이 통합된 샌드위치 혼성(NPA-SH)의 개발)

  • Kang, Mingyeong;Park, Mirye;Kim, Kang Eun;Lee, Taek-Kyun
    • Journal of Life Science
    • /
    • v.30 no.1
    • /
    • pp.26-31
    • /
    • 2020
  • Heterosigma akashiwo is a globally distributed raphidophyte that forms blooms and causes significant losses to the aquaculture industry in many coastal countries. The development of a fast and sensitive detection method is therefore required to facilitate the appropriate warning of harmful algal blooms. In this study, a nuclease protection integrated with sandwich hybridization (NPA-SH) assay was developed to both qualitatively and quantitatively detect H. akashiwo. The NPA, capture and signal probes were designed by nucleotide sequencing of H. akashiwo. The applicability of NPA-SH was evaluated using cultured H. akashiwo cells and field samples collected at Goseong Bay, Korea. The results show that this method has good applicability and effectiveness in analyzing cultured cells and field samples. A linear regression equation for the quantitative analysis of H. akashiwo was obtained, and the lower detection limit of the assay was 1×104 cells/ml. There was no statistically significant difference in the results of H. akashiwo quantitation using NPA-SH compared to those obtained using a microscope. These results indicate that NPA-SH can be a good alternative to the traditional microscopic method used to monitor H. akashiwo.

Effects of Settings in Dynamic Ranges and Frequency Modes on Ultrasonic Images (초음파 영상에서 동적영역과 주파수 방식의 설정에 따른 효과)

  • Yang, Jeong-Hwa;Kang, Gwan-Suk;Lee, Kyung-Sung;Paeng, Dong-Guk;Choi, Min-Joo
    • Journal of radiological science and technology
    • /
    • v.32 no.3
    • /
    • pp.277-283
    • /
    • 2009
  • It is important to get clinical ultrasonic images of good quality for accurate diagnosis. In this study, it observed the change of ultrasonic images against setting frequency, dynamic range(DR) and type of probes on ultrasonic scanner. In the experiment it evaluated image of LCS (Low Contrast Sensitivity) targets(-15, -6, -3, +3, +6, +15 dB) of a standard ultrasonic test phantoms(539,551, ATS, USA) similar to solid and cystic lesions. Its imaged from convex (C3-7IM) and linear probe (L5-12IM) on SA-9900 (Medison Ltd, Korea) scanner. The images obtained altering the setting parameters which are frequency(gen, pen, res, harmonic) mode and DR($40{\sim}100\;dB$). The quality of images evaluated compare with the nominal LCS value of target and measured LCS value. The results show that there was no significant changing of quality images altering DR 40, 60, 80, 100 dB against frequency in Convex probe but the image being the highest in LCS target at DR 60 dB, harmonic of frequency mode in the -15 dB target close to cystic lesion. In Linear probe, DR 40 dB, harmonic mode at -15 dB LCS target close to nominal value. It discussed necessity of evaluation about ROC(Receiver Operating Characteristic) from the psychological viewpoint and limit of evaluation from quantified images.

  • PDF

Development of TaqMan Quantitative PCR Assays for Duplex Detection of Dirofilaria immitis COI and Dog GAPDH from Infected Dog Blood (심장사상충에 감염된 개 혈액에서 Dirofilaria immitis의 COI와 개의 GAPDH를 이중 검출하기 위한 정량적 TaqMan PCR 분석법의 개발)

  • Oh, In Young;Kim, Kyung Tae;Gwon, Sun-Yeong;Sung, Ho Joong
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.51 no.1
    • /
    • pp.64-70
    • /
    • 2019
  • Dirofilaria immitis (D. immitis) is a filarial nematode that causes cardiopulmonary dirofilariasis in dogs. In the late stages of infection, infected dogs show one or more symptoms and advanced heart disorder with perivascular inflammation. To detect D. immitis specifically and efficiently in the early stages of infection, a duplex TaqMan qPCR assay was developed based on previous studies using primers and probes specialized to detect D. immitis cytochrome c oxidase subunit I (COI) and dog glyceraldehyde-3-phosphate dehydrogenase (GAPDH). As positive controls, plasmid DNAs were constructed from D. immitis COI or dog GAPDH and a TA-cloning vector. Simplex and duplex TaqMan qPCR assays were performed using the specific primers, probes, and genomic or plasmid DNA. The duplex reaction developed could detect D. immitis COI and dog GAPDH in the same sample simultaneously after optimization of the primer concentrations. The limit of detection was 25 copies for the simplex and duplex assays, and both showed good linearity, high sensitivity, and excellent PCR efficiency. The duplex assays for pathogen detection reduce the costs, labor, and time compared to simplex reactions. Therefore, the duplex TaqMan qPCR assay developed herein will allow efficient D. immitis detection and quantification from a large number of samples simultaneously.

Experimental Investigation of Characteristics Change by Kerf-Fill Material between Arrayed Elements of a Piezoelectric Transducer (압전 배열 트랜스듀서의 진동 요소간 kerf 충진 매질에 따른 특성변화의 실험적 고찰)

  • Kim, Jung-Soon;Kim, Moo-Joon;Ha, Kang-Lyeol
    • The Journal of the Acoustical Society of Korea
    • /
    • v.27 no.5
    • /
    • pp.215-220
    • /
    • 2008
  • The kerfs between arrayed piezoelectric elements in a medical ultrasonic transducer or a piezoelectric composite transducer are generally filled by polymeric materials. The boundary condition of the elements for lateral mode vibration is changed according to the kerf-filling materials, so that the resonance frequency for longitudinal mode of the transducer is also varied. In this study, to investigate the resonance frequency variation for an arrayed transducer experimentally, the piezoelectric vibration elements of $14mm{\times}0.22mm{\times}0.44mm$ were fabricated and those were linearly arrayed. And, the resonance frequencies were measured for three cases of kerf-filling condition, non-filling and two different kinds of epoxy filling. Conclusively, it is confirmed that the resonant frequency variation shows the similar tendency with the theoretical one for the longitudinal mode.

A Study on the Detection of the Rain Using Open-Ended Coaxial Cavity Resonator (한쪽 면이 열린 동축 공동 공진기를 이용한 빗물 감지에 관한 연구)

  • Lee, Yun-Min;Kim, Jin-Kuk;Hur, Jung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.24 no.9
    • /
    • pp.944-950
    • /
    • 2013
  • This paper is a study of a rain sensor using an open-ended coaxial cavity resonator which senses the amount of rain drops linearly. It shows that it will be used as a sensor to sense the amount of rain dropped on the windshield of an automobile based on the principle of varied resonant frequency and the loss according to the amount and characteristics of an dielectric lied on the open side of a resonator. The input and output ports are built in the both sides of the resonator and the input and output coupling probes are formed like 'ㄱ' shape. The response of rain drops were simulated by the radius of inner conductor of 2 mm, 5 mm, and 10 mm respectively and it showed that the raindrop was sensed most linearly and sensitively when the radius of inner conductor is 5 mm, We have measured that the resonant frequency have varied from 3.55 GHz to 3 GHz and the Q value have varied from 42.38 to 24.3 according to the variation of rain drop amount on the fabricated resonator. Therefore, it shows that the designed resonator can be applied as a rain sensor that measures the amount of rain drops linearly by using the resonant frequency as a measurement parameter.

Measurement of Thermal Diffusivity and the Optical Properties of a Carbon Nanotube Dispersion by Using the Thermal Lens Effect (열렌즈 효과를 이용한 탄소 나노 튜브 분산액의 열확산도와 광학적 특성 측정)

  • Park, Hyunwoo;Kim, Hyunki;Kim, Sok Won;Lee, Joohyun
    • New Physics: Sae Mulli
    • /
    • v.68 no.11
    • /
    • pp.1167-1172
    • /
    • 2018
  • Carbon nanotubes (CNTs) are structures of carbon atoms bonded together in hexagonal honeycomb shapes, with multi-walled CNTs having a very high thermal conductivity of $3000W/m{\cdot}K$ and single-walled CNTs having a conductivity of $6000W/m{\cdot}K$. In this work, the transmittance and the thermal diffusivity of a multi-walled carbon nanotube dispersion with a concentration of 1.5 M were measured using a single beam method, a dual beam method, and the thermal lens effect. The nonlinear optical coefficients were obtained by using the z-scan method, which moved the sample in the direction of propagation of the single laser beam, propagation and the thermal diffusivity was measured using a double laser beam. As a pump beam, a diode-pumped solid state (DPSS) laser with a wavelength of 532 nm and an intensity of 100 mW was used. As the probe beam, a He-Ne laser having a wavelength of 633 nm and an intensity of 5 mW was used. The experimental result shows that when the concentrations of the sample were 9.99, 11.10, 16.65, and 19.98 mM, the nonlinear absorption coefficients were 0.046, 0.051, 0.136 and 0.169 m/W, respectively. Also, the nonlinear refractive indices were 0.20, 0.51, 1.25 and $1.32{\times}10^{-11}m^2/W$, respectively, and the average thermal diffusivity was $1.33{\times}10^{-6}m^2/s$.

Degradation Evaluation of Mechanical Properties for 12Cr Ferrite Heat Resisting Steel by Reversible Permeability (가역투자율에 의한 12Cr 페라이트 내열강의 역학적 물성의 열화평가)

  • Ryu, Kwon-Sang;Kim, Min-Gi;Nahm, Seung-Hoon;Kim, Chung-Seok
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.30 no.5
    • /
    • pp.464-470
    • /
    • 2010
  • The integrity of the industrial equipment in use under high temperature and high pressure must be assessed by regularly measuring the degraded mechanical properties during service time. In order to nondestructively monitor the degraded mechanical properties of industrial equipment, a measuring method of the reversible permeability(RP) using surface type probe is presented. The method for measuring the RP is based on that RP is the differential value of hysteresis loop. The RP is exactly the foundation hatmonics induced in a detecting coil measured by lock-in amplifier tuned to a frequency of the alternating perturbing magnetic field. The peak of RP is measured around the coercive force. Steel material used in this work was 12Cr ferritic heat resisting steel. The eleven kinds of samples aged during different times under same temperature ($700^{\circ}C$) were prepared. Peak interval of reversible permeability(PIRP), Vickers hardness, and tensile strength measured for the aged samples decreased abruptly for short aging time (below 500 h), but the change became small at a long aging time. Vickers hardness and tensile strength linearly decreased as RIRP decreased, so the degraded mechanical properties of 12Cr ferritic heat resisting steel could be nondestructively evaluated by measuring RIRP.

형태변환형 투명 전극에 적용 가능한 그래핀-ITO 적층 필름 형성 및 특성 평가에 관한 연구

  • Kim, Jang-A;Kulkarni, Atul;Hwang, Tae-Hyeon;Kim, Tae-Seong
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2012.02a
    • /
    • pp.199-199
    • /
    • 2012
  • 최근 그래핀의 대면적 합성 및 롤투롤 전사 공정의 개발로 그래핀의 상용화가 가시화 되고 있다. 하지만, 그래핀의 독특한 특성인 선형적이고 밴드갭이 없는 에너지 띠 분포 때문에 반도체 소자로서의 직접적인 적용에는 한계가 있다. 이러한 문제를 해결하기 위한 돌파구로써, 그래핀 복합체의 연구와 개발이 활발히 진행되고 있으며 본 연구에서는 그래핀 복합 적층 구조를 다룬다. 이는 디스플레이, 초고속 반도체 소자, 고성능 광전자소자 및 초고감도 센서 등 다양한 분야에 대한 그래핀의 실용화 가능성이 높아진 것을 의미한다. 특히, 높은 가시광 투과도와 낮은 면저항으로 기존 투명 전극에 대표적으로 사용되고 있는 ITO (Indium Tin Oxide)를 그래핀으로 대체하는 것에 관한 연구가 활발히 진행되고 있다. 하지만 그래핀이 높은 전자이동도를 가지는 것에 비하여 비저항과 투과도 측면에 있어서는 ITO의 성능을 뛰어넘지 못하는 실정이다. 따라서 본 연구에서는 ITO가 가지는 취약점인 기판과의 약한 접착력, 높은 취성, 기판과의 열팽창률 차이 등의 공정상 문제점을 극복하고자 하였다. 그래핀 복합 적층 필름은 플라스틱 기판 (PET) 위에 열 화학기상증착법(Chemical Vapor Deposition, CVD)을 이용하여 합성한 그래핀을 전사하고, ITO 용액을 도포한 다음 다시 그래핀을 씌워 제작하여 샌드위치 구조(sandwich structure)를 형성하였다. 완성된 필름은 광학적, 전기적 특성 분석을 수행하였다. 광학적 분석으로는 라만 분광을 이용한 그래핀 품질평가와 파장대에 따른 광 투과도, 그리고 반사도 측정을 하였으며, 전기적 특성은 면저항을 측정함으로써 분석한다. 결함이 적고, 대면적에 걸쳐 한 층을 이루어야 하는 고품질 그래핀의 요구사항에 따라 라만 분광의 G, 2D, D 띠를 분석하였다. G와 2D 띠의 비율을 통해 그래핀의 층 수를, D 띠의 강도를 통해 결함의 유무를 판단하였다. 또한, 가시광 영역에서 90% 이상의 광 투과도를 보여야 하는 투명 소자의 요구사항 달성 정도를 UV-VIS를 이용하여 확인하였다. 마지막으로, 제작한 필름의 면저항 또한 4-프로브 멀티미터를 이용하여 측정하고, 일반적인 터치스크린의 면저항인 $500{\Omega}/sq$를 만족하는지 평가하였다.

  • PDF

A Study on Coating Film Thickness Measurement in vehicle Using Eddy Current Coil Sensor (와전류 코일 센서를 통한 차량용 코팅막 측정에 관한 연구)

  • Park, Hwa-Beom;Kim, Young-Kil
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.23 no.9
    • /
    • pp.1131-1138
    • /
    • 2019
  • The importance of coatings has been increasing for different purposes such as prevention of static electricity of auto parts or products, improvement of abrasion and corrosion resistance, and enhancement of esthetics. As a method for measuring the thickness of a coating film, a contact method with probe is commonly used. However, it is problematic that accuracy of the sensor is degraded due to sensor output distortion or load phenomenon, which is caused by a change in magnetic permeability of the core. In this study, we propose a method to reduce the measurement error of the coating film by applying the optimized circuit design and the thickness measurement algorithm to the problems caused by the nonlinear characteristics. The tests result which have been taken with different thickness coating samples show that the measurement accuracy is within ${\pm}2%$.