• Title/Summary/Keyword: 선택가이드라인

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Development and validation of analytical methods for pyrifluquinazon residues determination on agricultural commodities by HPLC-UVD (HPLC-UVD를 이용한 농산물 중 pyrifluquinazon 잔류시험법 개발 및 검증)

  • Do, Jung-Ah;Kwon, Ji-Eun;Kim, Mi-Ra;Lee, Eun-Mi;Kuk, Ju-Hee;Cho, Yoon-Jae;Chang, Moon-Ik;Kwon, Kisung;Oh, Jae-Ho
    • Analytical Science and Technology
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    • v.26 no.3
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    • pp.174-181
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    • 2013
  • Pyrifluquinazon is classified with a quinazoline insecticide that regulates food intake by controling the feeding behavior acting on the endocrine or nervous system of pests such as aphids and white fly. To keep safety on pyrifluquinazon residues in agricultural commodities a simple, accurate and rapid analytical method was developed and validated using high performance liquid chromatograph (HPLC-UVD). The pyrifluquinazon residues acidified with 1% formic acid in samples were extracted with acetonitrile and partitioned with hexane subsequently to dichloromethane then purified with silica solid phase extraction (SPE) cartridge. The purified samples were detected using HPLC-UVD. The method was validated using apple and pear spiked with pyrifluquinazon at 0.02, 0.05 and 0.1 mg/kg and hulled rice, pepper, soybean at 0.05 and 0.1 mg/kg. Average recoveries were 70.5~107.9% with relative standard deviation less than 10%. The result of recoveries and overall coefficient of variation of a laboratory results in Gwangju regional FDA and Daejeon regional FDA was followed with Codex guideline (CODEX CAC/GL 40). This method is appropriated at pyrifluquinazon residues determination and will be used as official method of analysis.

Animal Home Range Estimators - A Review and a Case Study - (동물 행동권 분석 방법론 고찰 - 괭이갈매기 사례 분석과 시사점 -)

  • Lee, Sung-Joo;Lee, Who-Seung
    • Korean Journal of Environment and Ecology
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    • v.36 no.2
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    • pp.202-216
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    • 2022
  • Animals exhibit certain behaviors and movement patterns as they react to their internal needs, external stimuli, and surrounding environments. They have a bounded range in which they mostly spend their time, and it is referred to as a home range. Based on the fact that the home range is a critical area for the survival and preservation of species, there has been a growing body of research on developing more precise home range estimation methods to use the estimated ranges as a ground for establishing an effective conservation policy since the early 1940s. Recent rapid advancements in telemetry technology that resulted in the presence of autocorrelation between locations with short time intervals revealed the limitations of the existing estimators. Many novel estimators have been developed to compensate for it by incorporating autocorrelation in calculating home ranges. However, studies on the animal home range are still in their early stage in Korea, and newly developed methodologies have not yet been adopted. Therefore, this study aims to introduce the foreign home range estimation methods and foster domestic research activities on home ranges. Firstly, we compared and contemplated seven estimators by categorizing them into geometrical and statistical methodologies and then divided them into estimators that assume independent observations and those that consider autocorrelation in each category. After that, the home ranges of black-tailed gulls (Larus crassirostris) were calculated using GPS tracking data for the month of June and derived home range estimators by applying the methodology introduced in this study. We analyzed and compared the results to discuss the strengths and weaknesses of each method. Lastly, we proposed a guideline that can help researchers choose an appropriate estimator for home range calculation based on the animal location data characteristics and analysis purpose.

Deep learning-based Multi-view Depth Estimation Methodology of Contents' Characteristics (다 시점 영상 콘텐츠 특성에 따른 딥러닝 기반 깊이 추정 방법론)

  • Son, Hosung;Shin, Minjung;Kim, Joonsoo;Yun, Kug-jin;Cheong, Won-sik;Lee, Hyun-woo;Kang, Suk-ju
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2022.06a
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    • pp.4-7
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    • 2022
  • Recently, multi-view depth estimation methods using deep learning network for the 3D scene reconstruction have gained lots of attention. Multi-view video contents have various characteristics according to their camera composition, environment, and setting. It is important to understand these characteristics and apply the proper depth estimation methods for high-quality 3D reconstruction tasks. The camera setting represents the physical distance which is called baseline, between each camera viewpoint. Our proposed methods focus on deciding the appropriate depth estimation methodologies according to the characteristics of multi-view video contents. Some limitations were found from the empirical results when the existing multi-view depth estimation methods were applied to a divergent or large baseline dataset. Therefore, we verified the necessity of obtaining the proper number of source views and the application of the source view selection algorithm suitable for each dataset's capturing environment. In conclusion, when implementing a deep learning-based depth estimation network for 3D scene reconstruction, the results of this study can be used as a guideline for finding adaptive depth estimation methods.

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Feeding Disorders in Autistic Spectrum Disorders (자폐 스펙트럼 장애 아동의 섭식장애: 문헌 고찰)

  • Min, Kyoung-chul;Shin, Jin-yong;Kim, Eun-hye
    • The Journal of Korean Academy of Sensory Integration
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    • v.21 no.3
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    • pp.79-102
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    • 2023
  • Objective : Autistic Spectrum Disorders(ASD) is a developmental disorder characterized by atypical sensory adaptation, communication problem, stereotyped behavior, and feeding disorders. The reasons for ASD feeding disorders are oral sensory motor, cognitive, behavioral, and social problems. Major symptoms include picky eating, selective eating, food refusal, food neophobia, limited food variety, and food aversion. ASD feeding disorders could be accompanied by various problems such as health and nutrition intake problems, feeding development, eating-related sociability, and family and caregiver stress. Feeding problems and disorders in ASD can present from birth. However, ASD is diagnosed by the age of 3, and there might be an appropriate treatment gap. Usually, symptoms of feeding disorders tend to decrease with age. However, the symptoms often remain, so early evaluation, intervention, and periodic checking are necessary. In this study, the general information about the feeding disorder characteristics of ASD, influencing factors, and intervention were described through a literature review. Conclusion : Sensory-based therapy and behavior-based therapies are generally used for feeding disorders in ASD. Sensory-based therapy is effective for food sensitivity and behavior-based therapy for food selection. As the symptoms of feeding disorders in ASD are diverse, a comprehensive approach includes play and participation, oral motor exercise, diet, and daily life. However, appropriate evaluation, intervention protocol, and guidelines for the treatment of feeding disorders in ASD are limited. Therefore, a complex approach based on a more systematic understanding is needed. Feeding rehabilitation specialists, such as occupational therapists, should provide appropriate evaluation and intervention.

A Study on The Introduction Method of Industrial Design for Small Business (중소기업의 산업디자인 도입방법에 관한 연구)

  • 이수봉
    • Archives of design research
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    • v.11 no.2
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    • pp.129-140
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    • 1998
  • This study aimed to grqJe for and present guideline roodel when the qJerator of domestic small manufacturing industry try to introch1ce the first industrial design by easier and more effective method. As the method of study, first of aiL examined the necessary of introducing industrial design throogh coosidering about the role and importance of small business. And next, analysed and examined the result of researching by enquete that is for qJerators of cbnestic small business. As a result, preconditioos for effective introducing industrial design were found. And, based 00 the preconditioos that were found through researching by enquete, examined the approachable introducing methods. Finally, set up the effectivable introducing methods of industrial design for doo1estic small manufacturing industry as a graphical model. As a result of study, First, the operator of small business who try to introduce industrial design needs to be well aware of these six cooditions as a prenise of effective awroach.1) coosciousness of role and versus a nation and a people of own industry Cereative 2) managing coosideratim and examinatim of a necessity of introducing industrial design as a cata1yst 3) A certain understanding aIntt essence and value of industrial design 4) Study and examinatim about a case of sucessful introducing industrial design arxl common introducing method of small business.5) Befarehand examinatim of introducing method making use of professional design organization and consultatim wicket 6) Prodent examination about the appointlrent puprpose, method of designer and infonmtion about designer. Second, as the position of small bnsiness that introduce industrial design fur the first time, it is confirmed that the aroroach going with introducing types - preliminary introducing, partitial introducing, regular introducing, whole industry level introducing - considered necessity rate of introducing industrial design and introducing range at the same time. This method is able to approach step by step, but it is confinmed that there is a characteristic in being able to select the method freely, and understanding easily for being coostructed visual form.

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Development and Validation of an Analytical Method for Determination of Fungicide Tridemorph in Agricultural Commodities Using LC-MS/MS (LC-MS/MS를 이용한 농산물 중 살균제 tridemorph의 시험법 개발 및 검증)

  • Pak, Won-Min;Do, Jung-Ah;Lim, Seung-Hee;Park, Shin-Min;Yoon, Ji-Hye;Lee, Dong-seouk;Chang, Moon-Ik
    • Journal of Food Hygiene and Safety
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    • v.32 no.4
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    • pp.290-297
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    • 2017
  • The purpose of this study was developed for the determination of tridemorph in agricultural commodities samples. Tridemorph residues in samples were extracted with acetonitrile, partitioned with saline water, and then purified using and aminopropyl ($NH_2$) SPE catridge. The purified samples were quantified and confirmed via liquid chromatograph-tandem mass spectrometer (LC-MS/MS) in positive ion mode using multiple reaction monitoring (MRM). Matrix-matched calibration curves were linear over the calibration ranges (0.005~2.5 ng) into a blank extract with $r^2$ > 0.999. The limits of detection and quantification were 0.001 and 0.005 mg/kg, respectively. The average recovery ranged between 75.9% and 103.7% at different concentration levels (LOQ, 10 LOQ, 50 LOQ, n = 5) with relative standard deviations (RSDs) less than 9.0%. An interlaboratory study was conducted to validate the method by Korea Advanced Food Research Institute. The average recovery ranged between 87.0% and 109.2% at different concentration levels (LOQ, $10{\times}LOQ$, $50{\times}LOQ$, n = 5) with relative standard deviations (RSDs) less than 8.0%. All values were consistent with the criteria ranges requested in the Codex guidelines (CAC/GL40, 2003) and Food Safety Evaluation Department guidelines (2016). The results prove that the developed analytical methods is accurate, effective and sensitive for tridemorph determination.

Development and Validation of an Analytical Method for Determination of Fungicide Benzovindiflupyr in Agricultural Commodities Using LC-MS/MS (LC-MS/MS를 이용한 농산물 중 살균제 벤조빈디플루피르의 잔류시험법 개발 및 검증)

  • Lim, Seung-Hee;Do, Jung-Ah;Park, Shin-Min;Pak, Won-Min;Yoon, Ji Hye;Kim, Ji Young;Chang, Moon-Ik
    • Journal of Food Hygiene and Safety
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    • v.32 no.4
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    • pp.298-305
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    • 2017
  • Benzovindiflupyr is a new pyrazole carboxamide fungicide that inhibits succinate dehydrogenase of mitochondrial respiratory chain. This study was carried out to develop an analytical method for the determination of benzovindiflupyr residues in agricultural commodities using LC-MS/MS. The benzovindiflupyr residues in samples were extracted by using acetonitrile, partitioned with dichloromethane, and then purified with silica solid phase extraction (SPE) cartridge. Correlation coefficient ($r^2$) of benzovindiflupyr standard solution was 0.99 over the calibration ranges ($0.001{\sim}0.5{\mu}g/mL$). Recovery tests were conducted on 5 representative agricultural commodities (mandarin, green pepper, potato, soybean, and hulled rice) to validate the analytical method. The recoveries ranged from 79.3% to 110.0% and then relative standard deviation (RSD) was less than 9.1%. Also the limit of detection (LOD) and limit of quantification (LOQ) were 0.0005 and 0.005 mg/kg, respectively. The recoveries of interlaboratory validation ranged from 83.4% to 117.3% and the coefficient of variation (CV) was 9.0%. All results were followed with Codex guideline (CAC/GL 40) and Ministry of Food and Safety guideline (MFDS, 2016). The proposed new analytical method proved to be accurate, effective, and sensitive for benzovindiflupyr determination and would be used as an official analytical method.

Development of an Analytical Method for Fluxapyroxad Determination in Agricultural Commodities by HPLC-UVD (HPLC-UVD를 이용한 농산물 중 Fluxapyroxad 잔류분석법 개발)

  • Kwon, Ji-Eun;Kim, HeeJung;Do, Jung-Ah;Park, Hyejin;Yoon, Ji-Young;Lee, Ji-Young;Chang, Moon-Ik;Rhee, Gyu-Seek
    • Journal of Food Hygiene and Safety
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    • v.29 no.3
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    • pp.234-240
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    • 2014
  • Fluxapyroxad is classified as carboxamide fungicide that inhibits succinate dehydrogenase in complex II of mitochondrial respiratory chain, which results in inhibition of mycelial growth within the fungus target species. This study was carried out to assure the safety of fluxapyroxad residues in agricultural products by developing an official analytical method. A new, reliable analytical method was developed and validated using High Performance liquid Chromatograph-UV/visible detector (HPLC-UVD) for the determination of fluxapyroxad residues. The fluxapyroxad residues in samples were extracted with acetonitrile, partitioned with dichloromethane, and then purified with silica solid phase extraction (SPE) cartridge. Correlation coefficient($R^2$) of fluxapyroxad standard solution was 0.9999. The method was validated using apple, pear, peanut, pepper, hulled rice, potato, and soybean spiked with fluxapyroxad at 0.05 and 0.5 mg/kg. Average recoveries were 80.6~114.0% with relative standard deviation less than 10%, and limit of detection (LOD) and limit of quantification (LOQ) were 0.01 and 0.05 mg/kg, respectively. All validation parameters were followed with Codex guideline (CAC/GL 40). LC-MS (Liquid Chromatograph-Mass Spectrometer) was also applied to confirm the analytical method. Base on these results, this method was found to be appropriate fluxapyroxad residue determination and can be used as the official method of analysis.

Agents Used for Pediatric Dental Sedation (소아치과 진정법에 사용되는 약제)

  • Kim, Jiyeon;Jeong, Taesung;Yang, Yeonmi;Yoo, Seunghoon;Choi, Sungchul;Shin, Teojeon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.43 no.1
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    • pp.109-116
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    • 2016
  • Sedation is an indispensable part of contemporary pediatric dentistry. The Korean Academy of Pediatric Dentistry (KAPD) organized the dental sedation committee to help members perform safer and more effective sedation. The committee surveyed 111 members who practice dental sedation to figure out the present state of sedation in 2014. According to the survey, 86% of the respondents indicated that they were interested in continuing education of sedation. The most interesting topic was sedation related emergency management, followed by safe dosages of sedative drugs. However, it is not realistic to establish the recommended dosages as a guideline since the selection of agents and dosages depend on various factors. In order to provide successful sedation, pediatric dentist should make an individual sedation plan for each procedure. It is important to understand not only the properties of each sedative, but also interactions with other drugs. This article reviews useful information of commonly used agents for dental sedation and summarizes the recommended dosages from the Physicians' Desk Reference (PDR) and some famous pediatric dentistry textbooks.

The guideline for choosing the right-size of tree for boosting algorithm (부스팅 트리에서 적정 트리사이즈의 선택에 관한 연구)

  • Kim, Ah-Hyoun;Kim, Ji-Hyun;Kim, Hyun-Joong
    • Journal of the Korean Data and Information Science Society
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    • v.23 no.5
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    • pp.949-959
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    • 2012
  • This article is to find the right size of decision trees that performs better for boosting algorithm. First we defined the tree size D as the depth of a decision tree. Then we compared the performance of boosting algorithm with different tree sizes in the experiment. Although it is an usual practice to set the tree size in boosting algorithm to be small, we figured out that the choice of D has a significant influence on the performance of boosting algorithm. Furthermore, we found out that the tree size D need to be sufficiently large for some dataset. The experiment result shows that there exists an optimal D for each dataset and choosing the right size D is important in improving the performance of boosting. We also tried to find the model for estimating the right size D suitable for boosting algorithm, using variables that can explain the nature of a given dataset. The suggested model reveals that the optimal tree size D for a given dataset can be estimated by the error rate of stump tree, the number of classes, the depth of a single tree, and the gini impurity.