• Title/Summary/Keyword: 서관

Search Result 302, Processing Time 0.025 seconds

Protective Effects of Nueihyuljunbang on LPS Combined PMA Induced Cytotocity in C6 Gilal Cell (LPS와 PMA에 손상된 신경교세포에 대한 뇌혈전방의 방어효과)

  • 서관수;문병순;성강경;임규상;신선호
    • The Journal of Korean Medicine
    • /
    • v.22 no.3
    • /
    • pp.1-10
    • /
    • 2001
  • Objectives : The water extract of Nueihyuljunbang (NHJB) has long been used for treatment of ischemic brain damage in Oriental Medicine. However, little is known about the mechanism by which the water extract of NHJB recovers brain cens from ischemic damage. Methods : To elucidate the protective mechanism on ischemic induced cytotoxicity, we investigated the regulation of lipopolysaccharide (LPS) and phorbol-12-myristate-13-acetate (PMA)-induced inducible nitric oxide synthase (iNOS) expression in C6 glial cells. Results : LPS combined PMA treatment for 72 hours in C6 glial cells markedly induced nitric oxide (NO), but treatment of the cells with the water extract of NHJB decreased dose-dependently nitrite formation. In addition, LPS combined PMA treatment for 72 hours induced severe celt death and lactate dehydrogenase (LDH) release in C6 glial cells. However, treatment of the celts with the water extract of NHJB did not induce significant change compared to control cells. Furthermore, the protective effects of the water extract of NHJB were mimicked by the treatment of NGMMA, a specific inhibitor of NOS. LPS combined PMA induced iNOS activation in C6 glial cells caused chromosomal condensation and fragmentation of the nuclei by caspase activation. The treatment of C6 glial cells with the water extract of NHJB might suppress apoptosis via caspase inhibition by regulation of iNOS expression. Conclusions : From the results, we suggest that the protective effects of the water extract of NHJB against ischemic brain damage may be mediated by regulation of iNOS during ischemic condition.

  • PDF

A Qualitative Evaluation Research on the Relationship Between Creative Thinking and an Infinite Creative Space Program (공공도서관 무한창조공간 프로그램과 창의성간의 관계에 대한 평가 연구)

  • Noh, Younghee;Kang, Jung-A;Jung, Eun-Ji
    • Journal of Korean Library and Information Science Society
    • /
    • v.46 no.2
    • /
    • pp.71-111
    • /
    • 2015
  • This study developed a program suitable for operating an infinite creative space within the public library, and analyzed the effect of promoting participants' creativity through a trial run of the program. To do this, we operated a "picture book making activities" program in the infinite creative space of J library located in Chungbuk. This program was performed for 18 elementary students in grades 3-6. Torrance TTCT (The Torrance Tests of Creative Thinking) tools were used in this study to measure the overall creativity. As a result, first, awareness of the importance and interest in environmental science was improved through the whole program process. Second, participants' problem-solving abilities improved during the program by having to derive a solution for a given problem through brainstorming. Third, storytelling ability improved after the story-creating elements of the program. Fourth, each participants' creativity was improved through creative activities. Fifth, by publishing the results of creative activities of participants as books, the self-esteem of participating children improved as well.

A Study on the Creative Interface Factors of Library Space on Ito Toyo - Focus on the Tama Art University New Libraries - (이토토요의 도서관 공간에 나타나는 창조적 인터페이스요소에 관한 연구 - 타마미술대학신도서관을 사례로 -)

  • Hwang, Mee-Young
    • Korean Institute of Interior Design Journal
    • /
    • v.19 no.3
    • /
    • pp.205-213
    • /
    • 2010
  • The importance of communication which is oriented to interaction, fusion and connection is more increased in the post-information society. The information environment is already realized as interface to reach immediately and freely to the databased information and knowledge. The contemporary libraries execute very important roles as an intellectual infra of modern times to deliver the great human achievement and create new culture. In the mean time, the rapid information-oriented society and the development of digital technology bring out big change in the traditional dispatch and receipt method of information. For this reason, libraries as the community space of visitors integrates physical space - electronic space and reconstructs new temporary culture and value to build the new interface that connects human to human, human to space and human to information. On the premise of these awareness, this study analysis the creative interface factor of Tama Art University New Libraries in Ito Toyo in order to research the function and the application method of modern libraries. And the results are follows. 1)We can make sure the significance of communication and the integration consciousness between digital technology and analogue sensitivity that is the characteristic of the post-information society. 2)We can classify for the creative interface factors by the character as space factor(Arcade, Gallery, Lounge, AV Booth, Cafe), facility/equipment factor(Laboratory, Media, Bar, Info Shelf, Media Seat) and furniture factor(Carrel, Desk, Mag Table, XI Shelf). 3)We can see that these interface factors change the stream of library users and that the library is constructed for library users to create and discovery something easily from books and modern technologies. And we can realize also that these factors are creative installation to lead out naturally the latent liberty sense of users.

Photosynthetic Variation by Cultural Environment in Sesame (참깨의 재배환경에 따른 광합성능력의 변화)

  • 서관석;김준기;김소연;이주열
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.29 no.2
    • /
    • pp.186-190
    • /
    • 1984
  • Photosynthetic rate of sesame varieties was investigated under the different cultural environments such as planting density or light intensity. The photosynthetic rate of Pungnyeon, monoculm variety, was higher than that of Kwangsan before flowering stage, while it was vice versa after the flowering stage. The maximum rate of photosynthetic rate was obtained three weeks after planting. The effects of light intensity on photosynthetic rate four weeks after planting was not apparent when the light intensity was reduced to the level of 35% and 55%, respectively. However, when the light intensity was reduced to 75% of the normal light intensity, the photosynthetic rate was also greatly reduced. The Photosynthetic rate after the flowering stage was reduced in the order of normal light, 35% and 75%, respectively.

  • PDF

Designing and Evaluating an Audiobook Service Model on Android Platform for the Visually-Impaired (안드로이드 플랫폼 기반 시각장애인용 음성도서 서비스 모델 구축 및 평가)

  • Jang, Won-Hong;Oh, Sam-Gyun
    • Journal of the Korean Society for information Management
    • /
    • v.32 no.2
    • /
    • pp.221-236
    • /
    • 2015
  • This paper describes the process and methodology followed in developing the Android-based LG Sangnam Audiobook service and an evaluation of its usefulness to the public. The methods included a survey of user needs, analysis of usage statistics, and user interviews. The study found that visually impaired users: 1) were greatly interested and willing to use smartphones if there were no barrier in cost and access; 2) preferred downloads to streaming services; 3) did not mind performance differences between real and TTS (text-to-speech) voices; 4) showed marked differences in book preferences according to age, 5) made about 14,000 downloads in 2014; and 6) indicated bookmarking and moving between pages and tables of content as the most important functions in using audiobooks.

A Study on the Wearing and Manufacturing Condition of Artificial Breast in Breast Cancer Patients with a Mastectomy (유방절제술을 시행한 유방암 환자의 시판 인조유방 착용 및 판매실태)

  • Koo, Da Som;Kim, Youn Joo;Nam, Yun Ja;Seo, Kwan Sik;Lee, Eun Shin;Noh, ong Young
    • Fashion & Textile Research Journal
    • /
    • v.22 no.1
    • /
    • pp.76-86
    • /
    • 2020
  • The study surveyed patients undergoing a mastectomy to understand their experience and requirements on artificial breasts and sales status. We retrieved 149 of the 150 surveyed questionnaires; subsequently, 144 questionnaires, excluding missing values, were used in the analysis. According to the results of the study, about 67% of respondents said that artificial breasts were not used after undergoing a mastectomy, and more than half of the breast cancer patients were not aware of the importance of artificial breasts. Breast cancer patients wearing artificial breast felt uncomfortable and hot during daily activities as well as experienced difficulty in size selection and purchase price burdens. The three most responded brands were selected based on the results of the survey that also investigated the sales status of the commercial artificial breast. Company A was selling artificial breast to reflect the consumer's functional requirements, and Company C was selling artificial breast with various kinds of reduced weight. However, it is thought that consumers will have less choice since artificial breasts have more limited forms than various types. Therefore, it is believed that the patient needs artificial breasts that satisfy the shape of various types of mastectomy. This study can be used as basic data for artificial breast development studies.

Modification of PLA/PBAT Blends and Thermal/Mechanical Properties (PLA/PBAT 블렌드의 개질과 열적, 기계적 특성)

  • Kim, Dae-Jin;Min, Chul-Hee;Park, Hae-Youn;Kim, Sang-Gu;Seo, Kwan-Ho
    • Applied Chemistry for Engineering
    • /
    • v.24 no.1
    • /
    • pp.104-111
    • /
    • 2013
  • Poymer blends of two degradable aliphatic polyesters, relatively expensive material polylactic acid (PLA) and relatively inexpensive material poly(butylene adipate-co-terephthalate) (PBAT), were used in this study. Three different kinds of modifiers were used with various amounts. Diisocyanate type methylenediphenyl 4,4'-diisocyanate (MDI) and hexamethylene diisocyanate (HDI) were used as modifiers and epoxy type coupling agents also used. The melt flow index (MFI) and dynamic viscoelasticity of various compositions of PLA/PBAT blends were studied. The mechanical property and morphology with respect to the fracture surface of PLA/PBAT blends were also investigated using tensile test and field emission scanning electronic microscopy, respectively. These tests were also used to verify the compatibility of PLA/PBAT and the effect of mechanical properties due to the use of modifiers. Tensile properties of PLA/PBAT blends modified with HDI were improved remarkably.

The Utility of State Public Library Standards for Planning and Evaluation: A Survey of Public Library Directors' Perceptions (공공도서관 계획과 평가에 있어서 도서관기준의 유용성: 미국 공공도서관장 인식조사를 중심으로)

  • Cha Mi-Kyeong
    • Journal of the Korean Society for Library and Information Science
    • /
    • v.33 no.2
    • /
    • pp.69-88
    • /
    • 1999
  • Despite the continuous development and provisions of state public library standards there has been little research about how useful they are for what aspects of public library activities The purposes of the present study are 1) to understand, from the directors points of view the utility of state standards for planning and evaluation: and 2) to explore the types of factors, related to the directors' backgrounds and/or the library planning and evaluation contexts associated with the directors perceptions. Through a self-administered mail questionnaire, 1,198 public library directors in Kansas Texas and Wisconsin were surveyed. and 737 directors replied ($61.5\%$ response rate). The directors perceived the standards useful for both planning and evaluation. Public library directors viewed the collection and service standards as more useful than administration, staffing and facilities standards. Library size and community involvement were associated with the directors perceptions, yet the directors professional background, was not significantly related to his or her perceptions. The findings suggest that public library directors perceptions of the utility of state standards need to be understood within the library condition and Its community context. and the emphasis on community based public library planning and evaluation should continue to be employed in the standards.

  • PDF

A Study on Revision & Development on the 'Model -Curriculum of the Library Science of the Junior College (전문대학도서관과의 모형교육과정 수정개발에 관한 연구)

  • So Si Joong
    • Journal of the Korean Society for Library and Information Science
    • /
    • v.18
    • /
    • pp.213-276
    • /
    • 1990
  • To revise and develop a 'Model' Curriculum for training the middle standing professionals equipped with professional technology and theories at the spot of the library, such process were executed as research on bibliographic material and literature, utilization of examination of various questionnaires, interviews with middle standing librarians at the spot of the library, a review on the operational state of the Professor's Association of Library Science of Junior Colleges, some consultation with the Research & Deliberation Committee on Curriculums, etc., and to review the present department of library science at the two-year course's short-term colleges or institutes in foreign countries, Germany which is thought to be similar to our nation's situations and its level of economy and Singapore which is considered to be a newly emerging nation were looked into typically. In particular, since studies on the curriculums of the Library Science Dept. of colleges had already preceded, thereby the framework of the 'Model' curriculum was already achieved, however to review how well such framework is applied to the spot of education and give some improvement on that, some unrelistic findings of different subjects in consideration with reality, while comparing those curriculum schedules of each Library Science Dept. with the 'Model' curriculum schedule, were supplemented or revised to be fit to reality. For some supplementing or revising proposals on the pre studied 'Model' curriculum, some tentative plans which focussed on each field respectively and some tentative plans which focussed on cultural subjects, required major subjects and elective subjects were suggested in duality to be referred to. On such a process of forming a harmony of educational theories and practice, it was planned to revise and develop curriculum in a sense emphasizing on practical exercise, and tried not to neglect on each of the fields of the curriculum centered on the areas of materials organization, linguistics, information resource, information science, library organization, & administration, etc. The study on curriculums should be performed flexible to be applied to the accelerating transition of sciences, and be good examples in instruction.

  • PDF

The Inquiry of Change of Mathematical Beliefs and Attitude in Elementary Cooperative Learning Class. (협동학습에서의 초등학생 수학적 신념 및 태도 변화 연구)

  • 서관석;안진수
    • School Mathematics
    • /
    • v.5 no.4
    • /
    • pp.541-553
    • /
    • 2003
  • The purposes of this study are to look into the changing processes of mathematical beliefs and attitudes of the students and to propose the plans how to manage cooperative learning, what can contribute to cognitive affective domains of mathematics learning in applying STAD-based cooperative loaming to mathematics class. So we, the researchers performed cooperative learning in the fifth grade of elementary school and did the exams of mathematical beliefs and attitudes, interviews, supplementary Questions. And students showed meaningful changes in 'the need of cooperative learning', 'critical thinking', 'the acceptance of thoughts of others'. Meanwhile, there were possibilities what all the members of one group can't recognize their errors in STAD, so we proposed 'Tongsinsa'. And we presented concrete methods how to reconstruct groups and somethings to consider when students are not satisfied with the group activities.

  • PDF