• Journal of Dairy Science and Biotechnology
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• v.36 no.4
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• pp.208-219
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• 2018

Emergence of drug resistant strains of Salmonella enterica threatens milk processing and related dairy industries, thereby increasing the need for development of new anti-bacterials. Developments of antibacterial drugs are largely aimed to target the bacterial envelope, but screening their efficacy on bacterial envelope is laborious. This study presents a potential biosensor for envelope-specific stress in which a gfp reporter gene fused to spy gene encoding a periplasmic chaperone protein Spy (spheroplast protein y) that can sense envelope stress signals transduced by two major two-component signal transduction systems BaeSR and CpxAR in Salmonella enterica serovars Enteritidis and S. Gallinarum. Using spy-gfp operon fusions in S. Enterititis and S. Gallinarum, we found that spy transcription in both serovars was greatly induced when Salmonella cells were forming the spheroplast and were treated with ethanol or a membrane-disrupting antibiotic polymyxin B. These envelope stress-specific inductions of spy transcription were abrogated in mutant Salmonella lacking either BaeR or CpxR. Results illustrate that induction of Spy expression can be efficiently triggered by two-component signal transduction systems sensing envelope stress conditions, and thereby suggest that monitoring the spy transcription by spy-gfp operon fusions would be helpful to determine if developing antimicrobials can damage envelopes of S. Enteritidis and S. Gallinarum.

• Journal of Digital Convergence
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• v.16 no.11
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• pp.221-230
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• 2018

Most of researchers and business futurists agree that traditional organizational designs are inadequate for coping with today's turbulent and increasingly networked world. Executives in small firms find that their organizations must tap into an extended network of partners to achieve the scale and power needed to succeed in industries dominated by large, global firms. As they attempt to build lean yet agile businesses, these executives are finding that they no longer rely on gut instinct alone. Neither can they simply copy organizational model that worked in the past. They must understand how organizational design choices influence operational efficiency and flexibility and, even more important, how to best align the organization with the environment and the strategy chosen to quickly and effectively sense and respond to opportunities and threats This research examines the capabilities required to build businesses that can survive and prosper in today's fast-faced and uncertain environment. The insights presented in this research have emerged from over 30 years of work with hundreds of executives and entrepreneurs as they struggled to build businesses that could cope with the demands of a rapidly changing, networked global economy. The insights from this research suggest that IT is an important enabler for developing the best capabilities required for success.

• Korean Journal of Construction Engineering and Management
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• v.20 no.5
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• pp.21-30
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• 2019

Environmental and energy issues such as abnormal climate and depletion of fossil fuel due to global warming have emerged as a critical task to threaten human survival. As a result, interest in the Zero Energy Building is increasing as it is an innovative building that can significantly contribute to building energy reduction and greenhouse gas reduction. In the market, however, the added cost of construction is a major stumbling block to the revitalization of the Zero Energy certification. In this study, general private apartment complexes were selected for research, detailed elements for Zero Energy certification were presented based on the construction criteria for eco-friendly houses from the initial design stage, and the cost efficiency analysis of the components for certification were presented. It has been analyzed that only Grade 3 certification can be implemented in apartments due to technical level and physical limitations. Also, after reviewing the cost trend during the lifecycle cost, all expenses can be recovered within 13 years after completion only in the case of grade 5 of the Zero Energy Building. The additional costs proposed in the present study are reflected appropriately in the review of projects for apartments scheduled for order in the future to contribute to the revitalization of the Zero Energy Building certification.

• Korean Journal of Poultry Science
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• v.49 no.2
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• pp.69-77
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• 2022

Antimicrobial peptides (AMPs) play an important role in innate immunity against pathogenic infections. AMPs exterminate pathogenic bacteria by disrupting cell membranes or inhibiting intracellular molecules. NK-2, first identified in pigs and derived from NK-lysin, has antimicrobial effects against bacteria and parasites. In this study, chimeric peptides (cpNK) of chicken and pig NK-2 and cpNK-derived peptides (cpNK-a1 and cpNK-a2) were synthesized, and their antimicrobial effects against various pathogenic bacteria such as Escherichia coli, Salmonella spp., Listeria monocytogenes, Staphylococcus aureus, and methicillin-resistant Staphylococcus aureus (MRSA) were investigated. The structure of chimeric peptides from chicken and pig NK-2, cpNK, include α-helix like NK-2 and peptide net charge was +9 like porcine NK-2. The cpNK peptide showed powerful bactericidal effects against most bacterial species, including MRSA, especially against gram-negative bacteria. Furthermore, cpNK-derived short peptides, cpNK-a1 and a2 also showed bactericidal activity, but the effects were weaker than those of cpNK. Therefore, we conclude that cpNK- and cpNK-derived short peptides have the potential to be used as antibiotic alternatives.

• Journal of Appropriate Technology
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• v.7 no.1
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• pp.102-114
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• 2021

India has recently experienced an acute crisis confronting the COVID-19 pandemic as confirmed cases exceeded 11.73 million in March 2021, which was the second worst scale only after the United States. The strict lockdown measures as well as the pandemic itself posed a serious threat of survival, in particular, to immigrant workers engaged in informal sectors, which triggered their reverse immigration. In case the COVID-19 pandemic continues in 2021, it is estimated that in the sector of tourism and service alone, more than 20 million jobs will disappear. The damage on industry is already being realized with the significant decrease of workforce. It is important to note, however, that jobless growth and labor polarization were observed even before the outbreak of COVID-19, and that the pandemic only served as one of the trigger catalysts that made those submerged problems burst out. In this study, we examine the structural problems in industry and labor market in India and consider the social context and efficacy of the "Make in India" or "Atmanirbhar Bhrat" policy. The latter initiative was presented in the trenches of the pandemic in 2020. While considering the complexity of problems, we would like to pursue a future-oriented approach and propose a direction in restructuring the labor market, attempted at reversing the critical conditions following the fourth industrial revolution and digitization into the shortcut to labor market restructuring.

• Composites Research
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• v.36 no.4
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• pp.281-287
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• 2023

Environmental pollution from waste and the climate crisis, due to rising global average temperatures, are reaching critical levels threatening human survival. Research is ongoing across various fields to solve this problem, with a key focus on developing eco-friendly, carbon-neutral materials. Our study aimed to integrate natural fibers, known for their environmentally friendly properties and lower carbon emissions, with carbon fibers. In general, combining high-strength and low-strength materials results in intermediate properties. However, we found that certain properties in our study exceeded those of typical carbon fiber composite materials. To validate this, we produced both carbon fiber composite materials and carbon fiber/natural fiber hybrid composite materials. We then compared their mechanical properties using a range of specific tests. Our results revealed that the hybrid composite material exhibited superior bending strength and fracture toughness compared to the carbon fiber composite material. We also identified the underlying mechanisms contributing to this strength enhancement. This breakthrough suggests that the use of hybrid composite materials may allow the production of stronger structures. Moreover, this can play a significant role in mitigating environmental pollution and the climate crisis by reducing carbon emissions, a major contributing factor to these global challenges.

• Korean Journal of Environmental Biology
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• v.40 no.1
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• pp.1-10
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• 2022

Global warming has a major impact on the Earth's precipitation and temperature fluctuations, and significantly affects the habitats and biodiversity of many species. Although the number of alien plants newly introduced in South Korea has recently increased due to the increasing frequency of international exchanges and climate change, studies on how climate change affects the distribution of these alien plants are lacking. This study predicts changes in the distribution of suitable habitats according to RCPs climate change scenarios using the current distribution of the invasive alien plant Conyza sumatrensis and bioclimatic variables. C. sumatrensis has a limited distribution in the southern part of South Korea. Isothermality (bio03), the max temperature of the warmest month (bio05), and the mean temperature of the driest quarter (bio09) were found to influence the distribution of C. sumatrensis. In the future, the suitable habitat for C. sumatrensis is projected to increase under RCP 4.5 and RCP 8.5 climate change scenarios. Changes in the distribution of alien plants can have a significant impact on the survival of native plants and cause ecosystem disturbance. Therefore, studies on changing distribution of invasive species according to climate change scenarios can provide useful information required to plan conservation strategies and restoration plans for various ecosystems.

• Korean Journal of Social Welfare Studies
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• v.42 no.2
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• pp.419-441
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• 2011

Cancer is a disease that threatens the individual's life. This is why the cancer patient goes through psychosocial pain in the form of a trauma. Thus, the previous researches have only focused on the cancer patient's psychosocial distress. However, the cancer patients who have grown more mature and brought upon positive changes in their lives have been clinically observed. Because of this, researches regarding the ways that social welfare can intervene in order to examine the cancer patients' positive changes and growth which breaks away from the previous pathological point of view of the cancer patients are being actively conducted in other countries. But it turns out that there aren't enough basic researches related to this topic and thereby the need to lay out the basis for social welfare intervention. Therefore, this research examines positive changes and growth that may result from the traumatic experience of having a cancer. The predictable factors regarding this are analyzed in order to provide the basic information that may promote clinical intervention for cancer patient's posttraumatic growth. For this, the information from 206 cancer patients who have agreed to participate in the research have been used to predict and evaluate the predictable factors for the cancer patient's post-traumatic growth and hierarchy multiple regression haven been analyzed. As the result of the research, main factor of the post-traumatic growth is found to be social support and coping. The positive reconstruction of coping has been discovered to be the strongest predictable factor for cancer patient's posttraumatic growth. Based on this result, the advice for further research and implications for social welfare have been given.

• Journal of Intelligence and Information Systems
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• v.29 no.4
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• pp.395-413
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• 2023

This research studied the effect of customer experience characteristics in offline home appliance stores on perceived value and revisit intention. Among the offline distribution of home appliances with more than 100 stores nationwide, two home appliance retailers (HiMart, E-Land), three hypermarkets (E-Mart, Homeplus, Lotte Hi-Mart), and two home appliance stores (LG Best Shop, Samsung Digital Plaza) were selected, and a survey was conducted on men and women in their 20s or older in Seoul, Gyeonggi, and Incheon who had visited and purchased the home appliance store within the last 6 months. As a result of the survey, a statistical analysis was conducted on a total of 330 samples using the PLS (Partial Least Squares) structural equation model and SPSS statistical package. Through this study, the following research results can be obtained. First, educational experience, deviant experience, and aesthetic experience had a positive (+) effect on the functional value. However, entertainment experience did not affect functional value. Second, educational experience, deviant experience, and aesthetic experience all had a positive (+) effect on emotional value. Third, both functional and sensory values had a positive (+) effect on the revisit intention. Fourth, it was confirmed that brand loyalty had no moderating effect between functional value and sensory value revisit intention. The results of this study show the structural relationship between customer experience characteristics, perceived value (functional value, sensory value), and revisit intention. This result provides guidelines on what activities home appliance offline stores should do at a time when online channels threaten the survival of offline channels.

• Journal of the Korean Society of Radiology
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• v.82 no.3
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• pp.600-612
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• 2021

Purpose To evaluate the long-term radiologic and clinical outcomes of stent-graft placement for the treatment of post-pancreaticoduodenectomy arterial hemorrhage (PPAH) based on the imaging findings of stent-graft patency and results of liver function tests. Materials and Methods We retrospectively reviewed the medical records of nine consecutive patients who underwent stent-graft placement for PPAH between June 2012 and May 2017. We analyzed the immediate technical and clinical outcomes and liver function test results. Stent-graft patency was evaluated using serial CT angiography images. Results All stent-grafts were deployed in the intended position for the immediate cessation of arterial hemorrhage and preservation of hepatic arterial blood flow. Technical success was achieved in all nine patients. Eight patients survived after discharge, and one patient died on postoperative day 28. The median follow-up duration was 781 days (range: 28-1766 days). Follow-up CT angiography revealed stent-graft occlusion in all patients. However, serum aspartate aminotransferase or alanine aminotransferase levels in all patients were well below those observed in hepatic infarction cases. Conclusion Stent-graft placement is a safe and effective treatment method for acute life-threatening PPAH. Liver function and distal hepatic arterial blood flow were maintained postoperatively despite the high incidence of stent-graft occlusion observed on follow-up CT.