• Title/Summary/Keyword: 생존시간

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A Statistical Methodology to Estimate the Economical Replacement Time of Water Pipes (상수관로의 경제적 교체시기를 산정하기 위한 통계적 방법론)

  • Park, Su-Wan
    • Journal of Korea Water Resources Association
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    • v.42 no.6
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    • pp.457-464
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    • 2009
  • This paper proposes methodologies for analyzing the accuracy of the proportional hazards model in predicting consecutive break times of water mains and estimating the time interval for economical water main replacement. By using the survival functions that are based on the proportional hazards models a criterion for the prediction of the consecutive pipe breaks is determined so that the prediction errors are minimized. The criterion to predict pipe break times are determined as the survival probability of 0.70 and only the models for the third through the seventh break are analyzed to be reliable for predicting break times for the case study pipes. Subsequently, the criterion and the estimated lower and upper bound survival functions of consecutive breaks are used in predicting the lower and upper bounds of the 95% confidence interval of future break times of an example water main. Two General Pipe Break Prediction Models(GPBMs) are estimated for an example pipe using the two series of recorded and predicted lower and upper bound break times. The threshold break rate is coupled with the two GPBMs and solved for time to obtain the economical replacement time interval.

An Adaptive Routing Protocol with a Balanced Energy Consumption For Wireless Ad-hoc Networks (애드혹 네트워크에서 에너지 소비 균형을 고려한 적응형 라우팅 프로토콜)

  • Kim, Yong-Hyun;Hong, Youn-Sik
    • The KIPS Transactions:PartC
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    • v.15C no.4
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    • pp.303-310
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    • 2008
  • To increase the lifetime of ad-hoc networks, a ratio of energy consumption for each node should be kept constant by equally distributing network traffic loads into all of the nodes. In this paper, we propose a modified AODV routing protocol to determine a possible route by considering a remaining battery capacity of a node and the degree of its usage. In addition, to reduce the amount of energy consumption during the path rediscovery process due to the huge amount of the AODV control messages the limited number of possible routes are stored into a routing table of a source node. When some links of a route fail, another possible path can be looked up in the table before the route discovery process should be initiated. We have tested our proposed method with a conventional AODV and a MMBCR method which is one of the power-efficient energy routing protocols based on the three performance metrics, i.e., the total remaining battery capacity, network lifetime and the ratio of data packets received by the destination node to compare their performance.

Effects of Bisphenol S on Viability and Reactive Oxygen Species of the Sperm and Ovarian Granulosa Cells in Pigs (Bisphenol S가 돼지정자와 난소내 과립막세포의 생존성과 활성산소에 미치는 영향)

  • Lee, Yu-Sub;Lee, Seunghyung;Yang, Boo-Keun
    • ANNALS OF ANIMAL RESOURCE SCIENCES
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    • v.29 no.4
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    • pp.166-171
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    • 2018
  • The effect of bisphenol S (BPS) on the viability and production of reactive oxygen species (ROS) was studied in boar sperm and ovarian granulosa cells. Boar semen was incubated in Beltsville thawing solution with either 0 or $5{\mu}M$ BPS for 3 and 6 h. The viability of sperm was analyzed by SYBR14/PI doubling staining, and production of ROS was detected. Ovarian granulosa cells were also treated with BPS for 24, 48, and 72 h. Then, cell viability (0, 5, 10, and $20{\mu}M$) and ROS production (only 0 and $5{\mu}M$ BPS) were assessed. The results showed that, BPS decreased sperm viability at 3 and 6 h, and that BPS increased ROS production (p<0.05). Also, BPS reduced the viability of ovarian granulosa cells (p<0.05), and stimulated ROS production (p<0.05). These results suggest that BPS damages sperm activation and ovarian granulosa cells in the reproductive system.

Effect of Sperm Preparation Technique on Subsequent In Vitro Development of Bovine Embryos (소 수정란 체외발달에 대한 정자분리방법의 효과)

  • 노규진
    • Journal of Embryo Transfer
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    • v.13 no.2
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    • pp.117-125
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    • 1998
  • 본 연구는 Percoll,Swim-up 그리고 Glass-wool 여과법의 세가지 정자분리 방법에 대한 정자 회수율, 생존율과 첨체반응율, 그리고 체외수정 후 배양시간에 따른 전핵형성율,수정란의 발달율과 세포할구수에 대한 효과를 조사하고자 실시하였다. 도축된 암소로 부터 채취한 난자를 22시간 체외배양 후 성숙된 난자를 체회수정시켰다. 수정 후 배양시간에 따라 존핵율을 조사하였으며 48시간에 분할율,192시간에 배반포기 발달율 및 세포할구수를 각각 비교 조사하였다. 정자의 첨체반응과 생존율은 처리군간에 차이가 없으나 회수율에 있어서 percoll 처리군이 다른 두 처리군보다 유의적으로 높았다(p<0.001).수정 후 배양시간별 전핵형성에 있어서도 percoll 처리군이 다른 두 처리군보다 빨리 진행됨을 볼 수 있다. 분할율에 있어서는 처리군간에 유의적 차이가 없으나.배반포기 발달율과 세포할구수에 있어서는 pecoll 처리군이 다른 두 처리군보다 유의적으로 높았다(P<0.05). 이상의 결과로 보아 percoll 처리에 대한 정자분리 방법은 정자 회수율이 높고 수정시 전핵형성 시간이 단축되어, 그 결과로 배반포기 발달율과 수정란의 세포할구수에 효과적임을 알 수 있었다.

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Studies on the Survival and In Vitro Fertilization Rates of Frozne-Thawed Porcine Embryos and Immature Oocytes (돼지 수정란 및 미성숙 난자의 동결융해 후의 생존율에 관한 연구)

  • 김상근;이명헌;남윤이
    • Korean Journal of Animal Reproduction
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    • v.22 no.2
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    • pp.187-194
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    • 1998
  • In order to determine suitable conditions for rapid freezing of porcine embryos, the kind and concentration of cryoprotectants, sucrose concentrations, equilibration time and thawing temperature in freezing medium were examined in relation to the survival of frozen-thawed oocyte and embryos. The results obtained are as follows : 1. The suitable concentrations of cryoprotoctant in the freezing medium which consisted of TCM-199+20% FCS were 1.5M for glycerol, 2.0M for DMSO, 2.5M for ethylene glycol, and 2.0M for propanediol. The sucrose concentration of 0.25M in the medium was found to optimal because the survival rate was markedly higher at this concentration when compared to the others. The survival rate was relatively high when the frozen embryos were thawed at 30$^{\circ}C$ in the freezing medium containing 2.5M cryoprotectants. The equilibration periods of 2.0 and 5.0 minutes revealed the higher survival in the media containing 1.5 or 2.1M glycerol when compared to 10 and 15 minutes. 2. The fertilization rates of frozen-thawed follicular oocytes which matured in vitro for 1, 12, 24 and 48 hours were 6.7~26.7% depending on the maturation time, and the rates were relatively high for those matured for a short period of time. The survival rates of frozen-thawed oocytes which matured in vitro for certain periods and fertilized were 10.0~30.0% depending on the maturation time.

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Observation of External Injury and Morphological Movement for Analysis of Recovery Possibility after Storage of the Juvenile Sea Cucumber, Apostichopus japonicus (돌기해삼(Apostichopus japonicus)의 보관 후 회복 가능성 파악을 위한 외상 및 형태학적 변화의 관찰)

  • KIM, Tae-Ik;SON, Maeng-Hyun;CHO, Jae-Kwon;JIN, Young-Guk
    • Journal of Fisheries and Marine Sciences Education
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    • v.28 no.4
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    • pp.1006-1013
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    • 2016
  • The observed external injury, movement and survival rate according to storage and recovery of the juvenile sea cucumber, Apostichopus japonicus(wet weight $1.0{\pm}0.2g$). The investigated application possibility of external injury(grade I~IV) and movement variation(buccal tentacle, motion, obversion, movement) for estimate of survival rate. The survival rate was observed through the recovery after storage of the sea cucumber in various water temperature(10, 15, 20, $25^{\circ}C$) and hours(3, 6, 12, 24 hour). Grade of external injury lower in the 24 hour experiment group of $20^{\circ}C$ water temperature and 12 hour experiment group of $25^{\circ}C$ water temperature. Buccal tentacle and movement strong related survival rate and external injury. In the case of $20^{\circ}C$ water temperature, survival rate was observed decrease 24 hours experiment. $25^{\circ}C$ water temperature was high to 6 hours but 12 hours experiment group observed decrease of the survival rate. The lethal time(LT10) of the juvenile sea cucumber was 15.73 hours($20^{\circ}C$) and 5.57 hours($25^{\circ}C$). The results of this study provided various measurement method of survival rate according to transportation of the juvenile sea cucumber for release.

Accessing the Clustering of TNM Stages on Survival Analysis of Lung Cancer Patient (폐암환자 생존분석에 대한 TNM 병기 군집분석 평가)

  • Choi, Chulwoong;Kim, Kyungbaek
    • Smart Media Journal
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    • v.9 no.4
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    • pp.126-133
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    • 2020
  • The treatment policy and prognosis are determined based on the final stage of lung cancer patients. The final stage of lung cancer patients is determined based on the T, N, and M stage classification table provided by the American Cancer Society (AJCC). However, the final stage of AJCC has limitations in its use for various fields such as patient treatment, prognosis and survival days prediction. In this paper, clustering algorithm which is one of non-supervised learning algorithms was assessed in order to check whether using only T, N, M stages with a data science method is effective for classifying the group of patients in the aspect of survival days. The final stage groups and T, N, M stage clustering groups of lung cancer patients were compared by using the cox proportional hazard model. It is confirmed that the accuracy of prediction of survival days with only T, N, M stages becomes higher than the accuracy with the final stages of patients. Especially, the accuracy of prediction of survival days with clustering of T, N, M stages improves when more or less clusters are analyzed than the seven clusters which is same to the number of final stage of AJCC.

An Optimal Path Planning for Survival Rate Maximization of Submarine (잠수함 생존율 극대화를 위한 최적 이동경로 계획)

  • Kim, Ki-Tae;Park, Se-Hoon;Cho, Sung-Jin;Jeon, Geon-Wook
    • Journal of the military operations research society of Korea
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    • v.36 no.3
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    • pp.135-145
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    • 2010
  • The submarine is very threatening and secretive weapon system that achieves missions under the sea. However, the submarine is faced with danger that can be attacked from the enemy when is detected by sensor or rose to the surface. This study will be planned optimal path to maximize the survival rate that considers submarine navigation capability in underwater and search activity of hostile warships. A mathematical programming model and a heuristic algorithm will be suggested in this study. The mathematical programming model is verified by using ILOG CPLEX. The submarine path, unit time(distance) of navigation, survival rate, and computation time is computed by using a heuristic algorithm.

Stability and Gastric Acid Resistance of Lactobacilli and Bifidobacteria in Commercial Yogurts (시판 요구르트 중 Lactobacilli 및 Bifidobacteria의 안정성 및 내산성 연구)

  • 이범진;박옥선;고준수;안태석;박승용
    • Korean Journal of Microbiology
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    • v.35 no.1
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    • pp.89-93
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    • 1999
  • Stability and gastric acid resistance of Lactobacilli and Bifidobacteria in commercial yogurts were invcstigated. It was noted that there was significant differences of stability and gastric acid resistance among yo-wts. The sutvival of Lactobacilli and B#idohacleria in commercial yogurts decreased as a function of time during storage and showed in the range of $10^7$-$10^8$ cfulml. The lower the pH was, the lower survival of Lactobacillus and B~dobaclerium was observed. The survival of Lactobacillz and Bifidobacteria in three yogurts appeared to be $10^3$-10$^4$ cfuIml. In the case of yogurt containing Bifidobncterza- loaded capsules, the gastric acid resistance of the Rifidobncteria was greatly enhanced and the survival after treatment in a gastric juice for 120 min was over 10' cfulml.

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Review for time-dependent ROC analysis under diverse survival models (생존 분석 자료에서 적용되는 시간 가변 ROC 분석에 대한 리뷰)

  • Kim, Yang-Jin
    • The Korean Journal of Applied Statistics
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    • v.35 no.1
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    • pp.35-47
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    • 2022
  • The receiver operating characteristic (ROC) curve was developed to quantify the classification ability of marker values (covariates) on the response variable and has been extended to survival data with diverse missing data structure. When survival data is understood as binary data (status of being alive or dead) at each time point, the ROC curve expressed at every time point results in time-dependent ROC curve and time-dependent area under curve (AUC). In particular, a follow-up study brings the change of cohort and incomplete data structures such as censoring and competing risk. In this paper, we review time-dependent ROC estimators under several contexts and perform simulation to check the performance of each estimators. We analyzed a dementia dataset to compare the prognostic power of markers.