• Title/Summary/Keyword: 생존도

Search Result 8,154, Processing Time 0.038 seconds

Effects of Copper / Zinc-Containing Superoxide Dismutase (Cu, Zn-SOD) and Catalase on Paraquat-Induced Injury in Primary Cultured Rat Skin Fibroblast (일차 배양한 백서 피부섬유아세포에서 Paraquat 독성에 미치는 SOD 와 Catalase 의 영향)

  • Cha, Jong Hui;Yu, Ui Gyeong
    • Journal of the Korean Chemical Society
    • /
    • v.38 no.1
    • /
    • pp.74-79
    • /
    • 1994
  • The participation of superoxide in initiating tissue damage derived from xenobiotics is best illustrated by paraquat intoxication. In the present study, the roles of superoxide dismutase and catalase on paraquat-induced cell injury were investigated using primary cultured rat skin fibroblast. The degree of cell injury was assassed by the conversion of reduced MTT to a blue formazan. Paraquat produced concentration-and time-related cell injury in cultured rat skin fibroblast. Paraquat induced-cell injury was aggravated by pretreatment of aminotriazol (AT: 10 mM), an catalase inhibitor, and attenuated by addition of catalase (100∼500 unit/ml). However, the effects of diethyldithiocarbamate (DDC : 10 mM), copper- and zinc-containing superoxide dismutase (Cu, Zn-SOD) inhibitor, and Cu, Zn-SOD on paraquat-induced injury were not significant. These results suggest that hydrogen peroxide might be more responsible factor than superoxide in the pathogenesis of paraquat-induced cell injury.

  • PDF

A Study on the Survival Rate and Factors of FDI to Korea: Focused on ICT Industry (외국인의 국내 직접투자의 생존율과 생존요인에 관한 연구: 정보통신산업을 중심으로)

  • Kim, Hyun Gyu
    • Journal of Korea Society of Industrial Information Systems
    • /
    • v.20 no.6
    • /
    • pp.67-78
    • /
    • 2015
  • The objective of this paper is to analyze survival rate and factors of FDI(Foreign direct investment) using FDI data of Ministry of Knowledge and Economy. Kaplan-Meier estimation was used. The result was as follows. M&A of FDI was much more risk than Greenfield FDI. .FDI to the IT-service industry was much more risk than FDI to the manufacturing industry. Partnership under 50% was much more risk than partnership over 50%. The accumulated survival rate of M&A was higher then Greenfield until fourth period but was lower than Greenfield after fourth period. The accumulated survival rate of M&A was lower than others from the first period to last period. There was no difference between Partnership under 50% and partnership over 50% to 4th period. After 4th period, Accumulated survival rate of partnership under 50% was higher than accumulated survival partnership over 50%.

A Study on Simple Calculation Method of Survival Time for Damaged Naval Ship Due to the Explosion (폭발에 의해 손상된 함정의 생존시간 간이계산법 연구)

  • Kim, Jae-Hyun;Park, Myung-Kyu
    • Journal of the Korean Society for Marine Environment & Energy
    • /
    • v.10 no.4
    • /
    • pp.211-217
    • /
    • 2007
  • Due to advanced new weapons and changes in the combat environment, survivability improvement methods for naval ship design have continuously evolved. Surface naval ships are easily detected by the enemy and, moreover, there are many attack weapons that may be used against surface naval ships. Therefore, it is important for modem naval ships, especially combat naval ships, to ensure survivability. In order to design a naval ship considering survivability, the designers are required to establish reasonable attack scenarios. An explosion may induce local damage as well as global collapse of the ship. Therefore, possible damage conditions should be realistically estimated at the design stage. In this study, an ALE technique was used to simulate the explosion analysis, and the survival capability of damaged naval ships was investigated. Especially, the author have establish the simple method of estimation of survival time for damaged naval ships.

  • PDF

A Study on Firm Survival Factors : Focusing on Korean Software Firms (기업의 생존요인 연구 : 국내 소프트웨어 기업을 중심으로)

  • Park, Gangmin;Kim, Jun Youn
    • Journal of Technology Innovation
    • /
    • v.26 no.4
    • /
    • pp.98-121
    • /
    • 2018
  • This article analyzes the survival of Korean software firms from 1995 to 2015 by Cox regression model and product-limit method. The results show that survival rates are different for each sector: IT service, package software, game software and internet service. In addition, firm growth and investment in research and development positively affect software firm's survival, while slack resources negatively affect the software firm's survival. The implication of this study is that characteristics of the software industry and technologies should be taken into consideration in survival strategy of software firms and government policy. Previous research on survival analysis has been mainly conducted in the manufacturing industry or at the special circumstance such as the foreign exchange crisis of Korea in the late 1990s. The contribution of this study is that expanding the survival analysis to software firms in Korea which are becoming more important recently.

Primary Radiation Therapy of Malignant Salivary Gland Tumors by Conventional Megavoltage Irradiation -Korea Cancer Center Hospital- (악성 타액선 종양의 방사선 치료 성적에 대하여 -원자력 병원의 10년 경험 ($1975.1{\sim}1984.12$)-)

  • Cho Chul Koo;Koh Kyoung Hwan;Yoo Seong Yul;Park Young Hwan;Park Woo Yoon;Shim Young Sang;Oh Kyung Kyoon
    • Radiation Oncology Journal
    • /
    • v.8 no.1
    • /
    • pp.35-43
    • /
    • 1990
  • Retrospective analysis of survival rates was undertaken in the patients of 58 cases treated with conventional radiation therapy for malignant salivary gland tumors between January 1975 and December 1984 in Korea Cancer Center Hospital (KCCH). They were patients whose long-term follow-up was possible and who had refused surgery or had had recurrences postoperatively. Out of 58 patients, 25 patients ($43.1\%$) had mucoepidermoid carcinomas and 24 patients ($41.3\%$) adenoid cystic carcinoma. Total actuarial survival rates at 5 years and 10 years were $68.2\%\;and\;31.8\%$ respectively, but disease-free survival rates, $43.2\%\;and\;13.0\%$, respectively. According to TNM stage, the survival rates at 5 years were $86.5\%$ in $T_1,\;40.0\%\;in\;T_2+T_3,\;and\;0\%\;in\;T_4$. In terms of histologic types, 5 years disease-free survival rate of adenoid cystic carcinomas ($40.1\%$) was lower than that of mucoepidermoid carcinomas ($49.8\%$) but overall survival rate ($77.3\%$) was much higher than that of mucoepidermoid carcinomas ($51.5\%$). There-fore, we concluded that the patients, who had had disease after failure of treatment, could survive during a certain period of time and their alive times were 2 years on the average. There was a difference in survival rates in the mucoepidermoid carcinomas in terms of histological grade of differentiation and it was a arbiter in prognosis: 5 YSR of low-grade was $78.8\%$ and higher 2 times than that of high-grade. There was no difference in survival rates according to location and sex. The number of patients having minor salivary gland tumors was 6 cases and their actuarial 5 YSR was $32.3\%$. Consequently, prognostic factors which influence the survival rates of patients with malignant salivary gland tumors are thought to be 1) histological subtypes 2) T and N staging (AJCC) 3) histological grade, especially in mucoepidermoids.

  • PDF

Long-Term Survival Analysis of Unicompartmental Knee Arthroplasty (슬관절 부분 치환술의 장기 생존 분석)

  • Park, Cheol Hee;Lee, Ho Jin;Son, Hyuck Sung;Bae, Dae Kyung;Song, Sang Jun
    • Journal of the Korean Orthopaedic Association
    • /
    • v.54 no.5
    • /
    • pp.427-434
    • /
    • 2019
  • Purpose: This study evaluated the long term clinical and radiographic results and the survival rates of unicompartmental knee arthroplasty (UKA). In addition, the factors affecting the survival of the procedure were analyzed and the survival curve was compared according to the affecting factors. Materials and Methods: Ninety-nine cases of UKA performed between December 1982 and January 1996 were involved: 10 cases with Modular II, 44 cases with Microloc, and 45 cases with Allegretto prostheses. The mean follow-up period was 16.5 years. Clinically, the hospital for special surgery (HSS) scoring system and the range of motion (ROM) were evaluated. Radiographically, the femorotibial angle (FTA) was measured. The survival rate was analyzed using the Kaplan-Meier method. Cox regression analysis was used to identify the factors affecting the survival according to age, sex, body mass index, preoperative diagnosis, and type of implant. The Kaplan-Meier survival curves were compared according to the factors affecting the survival of UKA. Results: The overall average HSS score and ROM was 57.7 and 134.3° preoperatively, 92.7 and 138.4° at 1 year postoperatively, and 79.1 and 138.4° at the last follow-up (p<0.001, respectively). The overall average FTA was varus 0.8° preoperatively, valgus 4.1° at postoperative 2 weeks, and valgus 3.0° at the last follow-up. The overall 5-, 10-, 15- and 20-year survival rates were 91.8%, 82.9%, 71.0%, and 67.0%, respectively. The factors affecting the survival were the age and type of implant. The risk of the failure decreased with age (hazard ratio=0.933). The Microloc group was more hazardous than the other prostheses (hazard ratio=0.202, 0.430, respectively). The survival curve in the patients below 60 years of age was significantly lower than those of the patients over 60 years of age (p=0.003); the survival curve of the Microloc group was lower compared to the Modular II and Allegretto groups (p=0.025). Conclusion: The long-term clinical and radiographic results and survival of UKA using old fixed bearing prostheses were satisfactory. The selection of appropriate patient and prosthesis will be important for the long term survival of the UKA procedure.

포커스 - 필동인쇄인, 생존권 사수 결의대회 개최

  • Jo, Gap-Jun
    • 프린팅코리아
    • /
    • v.11 no.3
    • /
    • pp.66-67
    • /
    • 2012
  • 필동인쇄인들의 자발적 모임인 필동경제인협의회(회장박장선, 이하 필경회)가 주축이 된 필동경제인 생존권 사수를 위한 비상대책위원회(위원장 박장선, 이하 비대위)가 지난 2월 7일 중구청 앞에서 500여명의 인쇄업 관계자들이 참석한 가운데 '필동 경제인 생존권 사수 결의대회'를 개최했다.

  • PDF

Semi-Markov 모형에 기초한 다중상태 생존자료의 준모수적 분석

  • 여성칠
    • Communications for Statistical Applications and Methods
    • /
    • v.5 no.3
    • /
    • pp.777-792
    • /
    • 1998
  • 병원의 임상연구실험에서 종종 환자들의 치료에 따른 병세의 호전상태를 여러단계로 분류하여 상이한 치료방법에 대한 치료효과간의 차이론 알고자 하는 경우가 있다. 이와 같이 다중상태의 생존자료를 분석하기 위해서 본 논문에서는 semi-Markov 모형에 Cox 회귀모형을 적용하여 회귀계수와 기저생존함수를 추정하고 이를 바탕으로 반응확률함수를 추정하였다. 그리고 본 논문의 결과를 실제 임상실험에서 얻어진 자료에 적용하여 분석하였다.

  • PDF

우리나라 과학기술 현황과 방위산업

  • Kim, Jin-Hyeon
    • Defense and Technology
    • /
    • no.3 s.157
    • /
    • pp.14-21
    • /
    • 1992
  • 기술자립 이외에는 국가생존의 안전과 평화의 보장수단이 없다는 사실을 직시하고 "우리도"가 아닌 "우리만"의 창조기술로 우리의 기술수준을 획기적으로 제고해야 할 것입니다. 따라서 군대가 국가존립을 위한 첨병의 역할을 맡고 있다면, 과학기술은 국가 생존을 위한 에너지 역할을 담당하고 있다고 볼수 있으며, 이젠 국가 생존을 위한 두 요소를 동질.동일성의 개념으로 파악해야 할 것입니다

  • PDF

생산비 절감을 위한 사양 관리

  • 고종열
    • 월간낙농육우
    • /
    • v.18 no.9 s.197
    • /
    • pp.94-99
    • /
    • 1998
  • 홀스타인 수송아지와 비육우의 가격폭락, 고가의 배합사료, 국내 조사료원의 부족, 우유 소비저하와 분유제고 증가, 유대지급 지연 등은 낙농가의 암담한 한숨만을 나오게 한다. 이제는 단순한 위기의식에서 벗어나 한국 축산 특히 낙농의 생존과 관련된 문제로서 모두가 생존을 위한 사양관리 전략을 수립해야 한다. 낙농가들은 생존전략으로 여러 가지 대응책을 마련하여 세균수감소를 위한 착유관리, 체세포 감소를 위한 도태와 착유 및 시설관리, 고품질우유 생산을 위한 사

  • PDF