• Title/Summary/Keyword: 생물권

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중금속 화학형태 연구에 의한 해양투기 하수슬러지의 생태위해성 평가

  • 권영택;한성대;안병영;윤지훈;김부생
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2003.05a
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    • pp.92-96
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    • 2003
  • 1) 우리나라의 하수슬러지 해양투기량은 발생량의 73%를 상회하고 있으며 최근에 급증하는 추세에 있다. 2) 슬러지를 비롯하여 해양에 투기된 유해성분은 해양생물권 오염도 증가의 큰 요인으로 작용하고 있었다. 3) 해양에 투기된 하수슬러지가 침강하여 퇴적층을 형성하였을 때 저서생태계에 영향을 미칠 수 있는 가능성은 아주 높았다. 4) 슬러지의 중금속 화학형태 분석 결과 생물이 이용 가능한 중금속 비율이 원소에 따라 차이는 있으나 총 함량의 80% 이상을 차지하는 경우도 있었다. 5) 해양생물권의 오염도 증가, 유해성분에 의한 생태계의 악영향 및 투기된 중금속의 높은 생물 이용 가능성 등을 고려할 때 하수슬러지 처리방법의 전환이 필요하였다.

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Anti-Melanogenic Effect of Dendropanax Morbiferus and Its Active Components via Protein Kinas e A/Cyclic Adenos ine Monophosphate-Responsive Binding Protein-and p38 Mitogen-Activated Protein Kinase-Mediated Microphthalmia-Associated Transcription Factor Downregulation

  • Bohyun Yun;Ji Soo Kim;Jung Up Park
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2022.09a
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    • pp.104-104
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    • 2022
  • Dendropanax morbiferus H. Lev has been reported to have some pharmacologic activities and also interested in functional cosmetics. We found that the water extract of D. morbiferus leaves significantly inhibited tyrosinase activity and melanin formation in α-melanocyte stimulating hormone (MSH)-induced B16-F10 cells. D. morbiferus reduced melanogenesis-related protein levels, such as microphthalmia? associated transcription factor (MITF), TRP-1, and TRP-2, without any cytotoxicity. Two active ingredients of D. morbiferus, (10E)-9,16-dihydroxyoctadeca-10,17-dien-12,14-diynoate (DMW-1) and (10E)-(?)-10,17-octadecadiene-12,14-diyne-1,9,16-triol (DMW-2) were identified by testing the anti-melanogenic effects and then by liquid chromatography-tandem mass spectrometry (LC/MS/MS) analysis. DMW-1 and DMW-2 significantly inhibited melanogenesis by the suppression of protein kinase A (PKA)/cyclic AMP (cAMP)-responsive binding protein (CREB) and p38 MAPK phosphorylation. DMW-1 showed a better inhibitory effect than DMW-2 in α-MSH-induced B16-F10 cells. D. morbiferus and its active component DMW-1 inhibited melanogenesis through the downregulation of cAMP, p-PKA/CREB, p-p38, MITF, TRP-1, TRP-2, and tyrosinase. These results indicate that D. morbiferus and DMW-1 may be useful ingredients for cosmetics and therapeutic agents for skin hyperpigmentation disorders.

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종합적인 지구환경 감시를 위한 지구관측시스템 (EOS) 사업

  • Park, Sun-Ki
    • Atmosphere
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    • v.12 no.4
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    • pp.56-68
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    • 2002
  • In this study, an overview of the Earth Observing System (EOS) program is provided with discussions on its spacecrafts and instruments, and on the scientific issues. The EOS satellites aim at monitoring the Earth environmental system by observing parameters of subsystems such as atmosphere, ocean, land, and biosphere. The first EOS flagship, Terra, was launched on December 1999. Five instruments onboard Terra can measure cloud and aerosol properties, radiation, terrestrial surface, and ocean color. The second EOS flagship, Aqua, which was launched on May 2002, loads six instruments that measure clouds, radiation, precipitation, terrestrial surface, ocean color and sea surface temperature. The observational data available from the EOS satellites may complement data from the Communication-Oceanography-Meteorology satellite, which will be launched in 2008, for meteorological and environmental forecasts.