• Title/Summary/Keyword: 생명 공학

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Korean representation of biotechnology : For college students and lay adults (생명공학에 대한 한국인들의 표상: 대학생들과 일반 성인들을 중심으로)

  • Kyo-Heon Kim
    • Korean Journal of Culture and Social Issue
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    • v.8 no.1
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    • pp.165-187
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    • 2002
  • This study examines Korean representation of the biotechnology and psychological factors which can influence lay people's perception and attitude about biotechnology. Korean college students(N=433) and lay adults(N=90) whom had college education participated in the study. Participants of the study 1 were asked to list words which comes to mind when associate with the biotechnology in broad sense, and several specific applications in health, medicines, agriculture and research. Participants of the study 2 were asked to list possible benefits and costs of biotechnology and their specific applications. In study 3, Participants responded the questionnaires about perceptions and attitudes of biotechnology. Korean people associated the biotechnology with its costs or risks and benefits. Korean college students mainly got the informations of the biotechnology from TV, newspapers, or internet. They trusted the scientist group and NGO group on their judgements about the assessment of risk and benefit of the biotechnology. College students showed the positive attitude with the applications in medicines and negative attitude with the applications in agriculture and public using of individual's genetic information. The radicalism, sensitivity in behavioral activation system, and trust/cynicism were to be found as a significant influencing factor for interest/knowledge and behavioral intention in related with biotechnology. Finally, more extensive knowledge of biotechnology did not lead to greater acceptance of it.

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Preparation of an Inactivated Influenza Vaccine Using the Ethanol Extracts of Medical Herbs (한약재 식물 에탄올추출물을 이용한 인플루엔자 불활화백신 제작)

  • Cho, Sehee;Lee, Seung-Hoon;Kim, Seonjeong;Cheong, Yucheol;Kim, Yewon;Kim, Ju Won;Kim, Su Jeong;Seo, Seungin;Seo, Dong-Won;Lim, Jae-Hwan;Jeon, Sejin;Jang, Yo Han
    • Journal of Life Science
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    • v.32 no.12
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    • pp.919-928
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    • 2022
  • As seen in the COVID-19 pandemic, unexpected emergence of new viruses presents serious concern on public health. Especially, the absence of effective vaccines or antiviral drugs against emerging viruses significantly increases the severity of disease and duration of viral circulation among population. Natural products have served as a major source for safe and effective antiviral drugs. In this study, we examined the virucidal activity of medical herb extracts with a view to discover novel antiviral agents with desired levels of safety and antiviral efficacy. Ethanol extracts of ten selected medical herbs were tested for antioxidant activity and in-vitro cytotoxicity in various animal cell lines. Of note, the herbal extracts showed broad and potent virucidal activities against rotavirus, hepatitis A virus, and influenza A virus. The extracts of Sorbus commixta and Glycyrrhiza uralensis showed strong virucidal activities against influenza A virus. We also examined whether the extracts of Sorbus commixta and Glycyrrhiza uralensis can be used as inactivating agents to prepare an inactivated viral vaccine. In a mouse model, influenza A virus inactivated by the extracts elicited high levels of neutralizing antibodies, and the vaccination provided complete protection against lethal challenge. These results suggest that herb-derived natural products can be developed to antiviral drugs as well as inactivating agents for preparation of inactivated viral vaccines.

Science News Frame: A Study of Longitudinal Framing Analysis for Biotechnology (과학뉴스(Science News)연구: 생명공학 뉴스의 장기적인 보도경향연구)

  • Kweon, Sang-Hee
    • Korean journal of communication and information
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    • v.32
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    • pp.7-48
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    • 2006
  • The study explores how Korea's major newspaper cover about science news, especially how newspaper frame biotechnology news including new source, news construction ways, coverage trend. The research has a research design to find out coverage pattern or model with frame theory. The result shows that the newspaper has some aspect of frame through out the biotechnology development in the section, theme, source, complexity. The section has been expend to the society and international section, while the theme shift from disease or cancer cure to life itself, genome, or stem cell. In the complexity, the biotechnology news stories have been developed a story plot (event-problem-development-solution). In the climax, the news coverage focuses on the explanation of biotechnology news.

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Infrastructure Services of KRIB Herbarium in IBMRC (KRIBB) (한국생명공학연구원 해외생물소재센터 식물표본관(KRIB)의 인프라 서비스)

  • Nam, Bo-Mi;Paik, Jin-Hyub;Lee, Changyoung;Choi, Sangho
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.42-42
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    • 2019
  • 한국생명공학연구원은 1985년 설립된 이후로 현재까지 국가적 연구개발 수요에 대응하여 바이오 분야의 기초 원천 연구, 인프라 구축 및 운영을 통하여 우리나라 생명과학기술 발전에 힘써왔다. 특히 2006년부터는 해외생물자원의 중요성에 주목하여 차세대 국가 핵심 전략 BT산업의 필수 원자재인 생물소재의 범지구적 확보, 보존 및 관리를 위하여 해외생물소재센터를 설치하였다. 이후 차례로 중국, 코스타리카, 인도네시아, 베트남의 4개 거점 센터를 개소 및 운영하여 권역별 해외생물소재의 공동연구 및 국제협력 네트워크를 구축하고 효과적인 소재 확보 및 관리를 도모하고 있다. 이와 같이 확보된 소재는 36개국에서 채집된 약 318과 3,406속의 36,500여점 (2019년 9월 기준)에 달하고 소재의 확증표본은 해외생물소재센터 식물표본관(KRIB)에 보관 중이다. KRIB표본관은 2000년 Index Herbariorum에 등록되었으며, 약 80,000여점의 건조표본을 소장하고 있다. 분류군수는 과별로 콩과>국화과>꼭두서니과 순으로 많았으며, 국가별로는 중국>베트남>코스타리카 순으로 조사되었다. 한국생명공학연구원 해외생물소재센터 및 식물표본관은 소재의 정확한 동정을 위한 분류학적 시설로서의 역할뿐 아니라 누구에게나 개방된 홈페이지를 통하여 해외소재의 표본정보, 표본이미지 및 민속학적 정보와 활성 등 가치 있는 정보를 제공하여 연구자들에게 다양한 활용지원 서비스를 제공하고 있다.

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Production, Purification, and Characterization of Phaseolus vulgaris Leghemoglobin a in Pichia pastoris (Pichia pastoris에서 강낭콩 Leghemoglobin a의 생산, 정제 및 특징)

  • Jun-Young, Kim;Da-Hee, Han;Geun-o, Park;Soo-Wan, Nam;Yeon-Hee, Kim;Han-Woo, Kim;Sung-Jong, Jeon
    • Microbiology and Biotechnology Letters
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    • v.50 no.4
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    • pp.508-511
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    • 2022
  • In this study, Phaseolus vulgaris (kidney bean) leghemoglobin a (PhLba) gene was cloned into pPICZαA and expressed in Pichia pastoris to sustainably produce a heme-carrying protein for organoleptic use in plant-based meat. The recombinant PhLba protein was secreted into the culture medium in a solubilized form, and the molecular weight of the purified PhLba was estimated to be 16.5 kDa using SDS-PAGE. In addtion, the yield of recombinant PhLba holoprotein was enhanced by supplementation of the cultivation medium with hemin. This result indicates that the apo-forms of PhLba can be effectively saturated with cofactor.

The prospect and the State of the Art for Marine Environmental Science and Technology from a Point of view of Marine Biotechnology (해양생명공학관점에서의 해양환경공학 현황분석과 전망)

  • Kim Sang-Jin
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.7 no.3
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    • pp.111-115
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    • 2004
  • In this manuscript the characteristics of marine environmental sciences and technology was depicted in the aspect of marine biotechnology, and the prospect of Korean society of Marine Environmental Engineering were suggested. Firstly definitions and main features of marine biotechnology and marine environmental sciences and technology were mentioned, and the long-term trends of environmental sciences and technology and the role of marine biotechnology to contribute for the development of marine environmental science and technology were described. The present state of the art for domestic research activities in the fields of marine environmental science and technology was reviewed and future directions for developing the Korean Society of Marine Environmental Engineering were suggested and discussed through understanding the present problems and solving those problems.

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