• The Science & Technology
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• v.33 no.5 s.372
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• pp.32-34
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• 2000

미국의 의사 알렌은 우리나라에 처음 들어온 서양의사로 1884년부터 20년동안 이 땅에 살아오면서 의술을 펴왔다. 알렌은 우리나라 최초의 근대식 병원 광혜원을 세웠으며 자객의 칼에 맞은 민비의 조카 민영익의 생명을 구해냈다. 민영익과의 인연으로 시의가 된 알렌은 어렸을 때 천연두로 시력을 잃었던 이승만을 치료해 시력을 회복시켜 주기도 했다.

• 전기의세계
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• v.42 no.2
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• pp.5-11
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• 1993

저자파가 인체에 미치는 영향을 개설하고 불필요한 전자파 잡음이 산업기기에 오동작을 일으켜 산업재해를 유발시킬 수 있다는 것을 간략히 설명하였다. 전자파가 우리들의 일상생활에 도움을 주기도 하며 건강을 해치기도 하고, 심지어는 불필요한 전자파가 2차재해를 유발하여 생산현장 근무자의 생명까지 앗아가기도 한다. 이러한 불요 전자파를 적절히 제어 운용하기 위하여 우리는 모든 지혜를 동원해야 할 것으로 생각된다.

• Communications of the Korean Institute of Information Scientists and Engineers
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• v.28 no.2
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• pp.41-47
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• 2010

• 전기의세계
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• v.28 no.5
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• pp.33-36
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• 1979

오늘의 학문은 너무나 세분화되고 있으며 또한 그경계가 불확실해지고 있다. 이러한 환경에서 생명활동과 전기현상에 관계를 가지고 있는 학문분야가 점차로 체계화되고 의용생체공학(biomedical engineering)으로 집약되어가고 있다.그러면 여기서는 의용생체공학을 이해하는데 도움을 주기위해 생체의 전기현상을 몇가지 소개하고 이것을 배경으로 의용생체공학에서 취급하고 있는 분야를 살펴봄으로서 이 학문의 위치를 확인하고져 한다.

• 어항어장
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• s.78
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• pp.35-38
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• 2007

안전점검결과 취약시설물 대부분이 정밀점검을 통하여 판단되었으므로, 향후 연차적으로 정밀점검 대상항의 확대 추진과 주기적인 저밀안전진단 실시방안도 검토되어야 할 것이다.아울러, 자연재해로부터 어민의 생명과 재산을 안전하게 보호하기 위해 보다 더 체계적이고 과학적인 안전유지관리시스템과 첨단장비도 점차 마련되어야 할 것이다.

• The Monthly Diabetes
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• s.149
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• pp.18-19
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• 2002

당뇨병의 여러 합병증은 주기적인 검진과 함께 환자들도 인식을 많이 하고 있다. 그러나 상대적으로 생명과는 별 연관이 없는 듯 보이고 환자에 따라서는 일시적일 수 있는 신경병증과 이에 따른 발병변에 관해서는 관심이 덜한 편이다. 하지만 조금만 신경쓰면 별 문제없이 생활할 수 있는 발질환을 대수롭지 않게 여기다 결국 조기진단과 치료가 안되어 고생하고, 심지어 발을 절단해 삶의 질을 떨어뜨리는 환자가 많다.

• Journal of Life Science
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• v.19 no.5
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• pp.620-624
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• 2009

D-Ala2-Leu5-enkephalin (DADLE), a hibernation inducer, can induce hibernation-like state in vivo and in vitro. We treated U937 human leukemia cancer cells with DADLE and investigated its possible effect on transcription and proliferation. Treatment of U937 cells with DADLE resulted in growth inhibition and induction of apoptotic cell death on high-dose as measured by MTT assay and DNA flow cytometer analysis. Bcl-XL, c-IAP-2 and survivin genes especially showed decreases in mRNA levels. DADLE treatment also inhibited the levels of cyclooxygenase (COX)-2 mRNA without alteration of COX-1 expression. DNA flow cytometer analysis revealed that DADLE caused arrest of the cell cycle on low-dose, which was associated with a down-regulation of cyclin E at the transcriptional level. DADLE treatment induced a marked down-regulation of cyclin-dependent kinase (Cdk)-2, -4 and -6. In addition, treatment with DADLE decreased telomere associated genes such as, c-myc and TERT, and increased TEP-1 in U937 cells. These results suggest that DADLE can be an inhibition agent in the cell cycle of the human leukemia cancer U937 cell.

• Journal of Life Science
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• v.29 no.1
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• pp.105-111
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• 2019

In recent years, progress has been made in the search for the development of new anti-cancer agents by employing specific inhibitors of histone deacetylase (HDAC)-6 to block signal transduction pathways in cancer cells. This study examined the effects of tubastatin A (TubA), an HDAC-6 inhibitor, on the growth and development of immature oocytes in murine ovaries using RNA sequencing analysis. The results from a gene set enrichment analysis (GSEA) indicated that the expression of most of the gene sets involved in the cell cycle and control and progression of meiosis decreased in the TubA-treated group as compared with that in germinal vesicle (GV) stage oocytes. In addition, an ingenuity pathway analysis (IPA) suggested that TubA not only caused increased expression of p53 and pRB and decreased expression of CDK4/6 and cyclin D but also caused elevated expression of genes involved in the control of the DNA check point in G2/M stage oocytes. These results suggest that TubA may induce cell cycle arrest and apoptosis through the induction of changes in the expression of genes involved in signal transduction pathways associated with DNA damage and the cell cycle of immature oocytes in the ovary.

• Journal of Life Science
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• v.13 no.1
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• pp.42-46
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• 2003

Photoplethysmogram is widely used to measure heart rate and arterial blood oxygen saturation in human. This paper describes radial pulse waves recorded by photoplethysmogram with 940 nm wavelength infra red light. Radial pulse waves were varied according to the recording site. When recorded on the skin over radial artery, the radial pulse wave was inverted, comparing to the photoplethysmogram at fingertip. The mechanism of inverted pulse wave seemed to be caused by the change of the blood volume in the subcutaneous tissue between radial artery and the skin, which was reduced during systolic period and increased during diastolic period of the cardiac cycle. These results suggest that radial arterial wall may reflect infra red ray.

• Journal of Life Science
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• v.13 no.6
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• pp.889-895
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• 2003

This experiment was carried out to investigate the effect of subirrigation of Dolrido on the growth and development of stem cutting and young roes plant. Plant growth was measured at 20, 40, and 60 days after subirrigation of Dolrido. Plant height, stem diameter, number of leaves, leaf area and root length of cutting rose subirrigation were more affected than those of control. The growth of young seedling was significantly affected by subirrigation of Dolrido. Plant height, number of leaves, stem diameter, leaf area, fresh and dry weight were increased with subirrigation of Dolrido. However, T/R ratio was not affected by subirrigation of Dolrido. Growth of seedlings was promoted after 60 days treatment of Dolrido.