• 열린충남
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• s.54
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• pp.6-9
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• 2011

올해 2회를 맞이하는 2011금산세계인삼엑스포는 9월 2일부터 10월 3일까지 32일간 금산군 신대리 국제인삼유통센터 일원에서 "생명의 뿌리, 인삼"이라는 주제로 개최된다. 인삼을 통한 금산지역의 경제적 도약과 건강 생명도시로서 금산의 미래 비전을 제시하는 세계적인 수준의 엑스포이다. 자연의 과학이 만든 생명밸런스라는 부제 아래 인삼의 생명산업화의 가능성을 보게 될 행사 속으로 미리 떠나보자.

• The Korean Publising Journal, Monthly
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• s.216
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• pp.16-17
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• 1997

적막한 시가 자본주의 사회에서 외로운 행보를 계속한다. 올 상반기에 나온 여러권의 시집은 창조와 파괴의 장소, 그 적막한 생명의 원천을 보여준다. 그러기에 지금이야말로 시의 여백의 시대, 아니 시의 르네상스가 도래할 시기인지도 모른다.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.11a
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• pp.171-171
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• 2005

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.11a
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• pp.320-320
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• 2005

• The Korean Society of Law and Medicine
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• v.11 no.1
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• pp.297-329
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• 2010

The bioethics as a comprehensive and normative control method of life sciences including the technology of advanced medical care, on the one hand, it has modified the conditions for allowing the progress of life sciences. On the other hand, it has put the brakes on attempts of life sciences violating the dignity and value of human beings, natural order. Positively, bioethics presents ethical bases, suggests organization of the legal and institutional conditions, and enables elimination of the legal and institutional obstacles, for the progress of life sciences. Negatively, it has presented justifiable prospects and road maps of life sciences, not to take indiscreet and intemperate turn of violating the dignity and value of human beings, natural order, and its such roles must be carried on.

• Journal of Korean Medical classics
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• v.18 no.3 s.30
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• pp.9-16
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• 2005

종의역학적각도간(從醫易學的角度看), 우주적팽창일수축반복가설부합음양소장과정. 우주팽창시(宇宙的膨是)‘양생음장(陽生陰長)’, ‘양성음쇠(陽盛陰衰)’적과정(的過程) ; 우주수축시(宇宙收縮是)‘양살음장(陽殺陰藏)’, ‘음성양쇠(陰盛陽衰)’적과정(的過程). 종수축도팽창(從收縮到膨脹), 종팽창도수축(從膨脹到收縮), 기전환점시양극혹음극적상태(其轉換點是陽極或陰極的狀態), 응용(應用)’음극변양(陰極變陽), 양극변음(陽極變陰)‘적음양극변원리(的陰陽極變原理). ${\lceil}$내경(內經)${\rfloor}$인위물질화시공(認爲物質和時空), 시간화공간본질상시일치적(時間和空間本質上是一致的), 도시종기파생출래적(都是從氣派生出來的). ${\lceil}$내경(內經)${\rfloor}$이경인식도료시공적통일성화상대성(已經認識到了時空的統一性和相對性). 저여애인사탄상대론적시공관유상동지처(這與愛因斯坦相對論的時空觀有相同之處). 서방과학적시공관시통과대물질실체이급물질상호관계적관찰이형성적물리시공관(西方科學的時空觀是通過對物質實體以及物質相互關係的觀察而形成的物理時空觀) ; 의역시공관시통과대포괄인류재내적천지만물적일절생명활동현상적관찰이형성적생명시공관(醫易時空觀是通過對包括人類在內的天地萬物的一切生命活動現象的觀察而形成的生命時空觀).

• Journal of Korean Medical classics
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• v.19 no.4
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• pp.126-135
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• 2006

목전(目前), 수착여의학상관적현대과학기술적급속발전(隨着與醫學相關的現代科學技術的急速發展), 의료계대의학윤리적요구월래월고(醫療界對醫學倫理的要求越來越高), 의학윤리사상재동양주요원요의생적윤리이발전기래(醫學倫理思想在東洋主要園繞醫生的倫理而發展起來). 우기도료명대(尤其到了明代), 장개빈근거(張介賓根據) "소문(素門) 방성쇠론(方盛衰論)"중(中)"부실인정(不失人情)"문장(文章), 제출료인환자여감호인이급의자지간각유기구체정황(提出了因患者與監護人以及醫者之間各有其具體情況), 소이필수분별가이타선료해(所以必須分別加以妥善了解), 즉주요원요의생윤리사상언급환자혹감호인적구체정황(卽主要園繞醫生倫理思想言及患者或監護人的具體情況). 종관기내용가지(綜觀其內容可知), 재환자방면(在患者方面), 장개빈인위의생응사선응예지환자적각종정황(張介賓認爲醫生應事先應預知患者的各種情況), 여약환자심리존유측시의생능력적상법(如若患者心里存有測試醫生能力的想法), 나마치료효과취불회호. 재감호인방면(在監護人方面), 장개빈인위유어개인적친분혹이해관계(張介賓認爲由於個人的親分或利害關係), 왕왕회사환자화의생면임군경(往往會使患者和醫生面臨窘境), 저일점응가이주의(這一點應加以注意). 재의생방면(在醫生方面), 장개빈인위의생응숙지자신적의학능력(張介賓認爲醫生應熟知自身的醫學能力), 불능기편환자(不能欺編患者), 야불능설비방기타의생적화(也不能設誹謗其他醫生的話). 령외, 장개빈종기보편성의학윤리사상(張介賓從其普遍性醫學倫理思想), 인위의사응구비총명적자질(認爲醫師應具備聰明的資質), 필수유일과열애생명적심(必須有一顆熱愛生命的心), 이차환인위의생응다독의경(而且還認爲醫生應多讀醫經), 다배양사(多拜良師), 정확지장악약물급진단치료질병적방법(正確地掌握藥物及診斷治療疾病的方法).

• Journal of Life Science
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• v.14 no.5
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• pp.815-820
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• 2004

A bacterum containing antitumor activity was isolated from traditional korean food, Jeotgal. Through the 16s rRNA sequence analysis, the bacterium was identitied as a strain of Bacillus subtilis SW-l. The best culture condition for antitumor activity of the bacterium is 3% of soluble starch and 1 % of yeast extract as corbon and nitrogen sources, respectively. Cytotoxicitic concentrations of the culture supernatant of B. subtilis SW-1 against cancer cell lines, A549 and SK-OV3 were 30 ul/ml and 40 ul/ml, respectively, as $IC_{50}$/ values. In DNA fragmentation assay, the culture supernatant showed the programmed cell death (apoptosis) to cause degrading the chromosomal DNA like ladder. Taken together, the culture supernatant of the B. subtilis SW-1 has some possibility to be used as an antitumor agent.

• Analytical Science and Technology
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• v.21 no.4
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• pp.245-258
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• 2008

Five triterpenic acids as marker compounds were extracted and isolated from Prunellae Spica by column chromatography and reversed-phase high-performance liquid chromatography (HPLC), and their purity was determinated by HPLC (purity ${\geq}90%$). Molecular weight and elemental compositions of the five marker compounds were determined by fast atom bombardment high-resolution mass spectrometry (FAB-HRMS). The structural determination of the five marker compounds was carried out fast atom bombardment collision-induced dissociation tandem mass spectrometry (FAB-CID-MS/MS). The collision-induced dissociation (CID) of protonated molecules $[M+H]^+$ and deprotonated molecules $[M-H]^-$ produced diverse product ions due mainly to retro Diels-Alder reaction (RDA), dehydration and decarboxylation. Moreover, the CID-MS/MS spectra of the $[M-H]^-$ ions were observed charge-remote fragmentation (CRF) patterns. On the basis of interpretation of CID-MS/MS spectra, structural elucidation of triterpenic acids isolated from Prunellae Spica was clearly performed.

• Journal of Life Science
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• v.33 no.1
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• pp.43-49
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• 2023

Houttuynia cordata belongs to the Saururacease family and its leaves, stems, and roots have been used as oriental medicines to treat pneumonia, acute or chronic bronchitis, enteritis, and abscesses and to remove extravasated blood. Recently, the antioxidant, anti-inflammation, antibacterial, and anti-proliferation activities and protection abilities of H. cordata against liver and neuron cell damage have been reported. In this study, ethanol extract and its solvent fractions (fractions of hexane, ethyl acetate, butanol, and water residue) were prepared, and their antithrombosis, antidiabetes, antioxidant, and hemolysis activities were evaluated. The ethyl-acetate fraction of H. cordata (EF-HC) showed the highest polyphenol and flavonoids contents among the fractions and exhibited strong antithrombosis and antioxidant activities. The EF-HC at 5 mg/ml showed 2.09-folds of thrombin time, 2.19-folds of prothrombin time, and 1.69-folds of activated partial thromboplastin time compared to the their solvent control and 30.9, 19.9, and 49.6 ㎍/ml of RC₅₀ against DPPH, ABTS, and nitrite radicals, respectively. Furthermore, the EF-HC did not show any hemolytic activity up to 1 mg/ml, whereas the hexane fraction of H. cordata showed 55% hemolysis at 1 mg/ml. This is the first report of the antithrombosis activity of H. cordata. Our results suggest that quercitirin, hyperoside, orientin, and isoquercitrin in EF-HC are related to its antithrombosis and antioxidant activities and that the EF-HC could be developed as a promising antithrombosis agent.