• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.8
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• pp.1587-1595
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• 2016

P wave is cardiac parameters that represent the electrical and physiological characteristics, it is very important to diagnose atrial arrhythmia. However, It is very difficult to detect because of the small size compared to R wave and the various morphology. Several methods for detecting P wave has been proposed, such as frequency analysis and non-linear approach. However, in the case of conduction abnormality such as AV block or atrial arrhythmia, detection accuracy is at the lower level. We propose P wave detection algorithm through adaptive threshold and QRS peak variability. For this purpose, we detected Q, R, S wave from noise-free ECG signal through the preprocessing method. And then we classified three pattern of P wave by peak variability and detected adaptive window and threshold. The performance of P wave detection is evaluated by using 48 record of MIT-BIH arrhythmia database. The achieved scores indicate the average detection rate of 92.60%.

• The Korean Journal of Pharmacology
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• v.20 no.2
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• pp.35-47
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• 1984

Contents of immunoreactive ${\beta}-endorphin$ and maximum of $^3H-morphine$ binding was measured in the rat midbrain homogenates from different subgroups at 24 hour interval over 24 hours. Animals were adapted to the light-dark cycle(L : D, 12: 12) or constant darkness (D : D, 12 : 12) for 3 weeks. After the adaptation, 0.5ml of physiologic saline or drug was administered twice a day for 2 weeks. A highly significant circadian rhythm with the peak$(94.8{\pm}7.7\;fmole/mg\;protein)$ at 06:00 and the nadir $(27.6{\pm}2.4\;fmole/mg\;protein)$ at 18:00 was observed in constant of group. Constant dark or treatment of reserpine, pargyline, imipramine, amphetamine and chlorpromazine modified the diurnal rhythm in the time of peak and nadir, shape, phase amplitude and 24 hour mean of ${\beta}-endorphin$ contents. Opiate receptor binding by $^3H-morphine$ also showed highly significant diurnal change in control and constant dark adapted rats. Statistical analysis by one-way analysis of variance and two-way analysis of variance indicates that the·re are highly significant differences between the diurnal change of ${\beta}-endorphin$ in control and those constant dark adapted and drug treated groups. However diurnal change of Maximum $^3H-morphine$ binding is closely related to the change of ${\beta}-endorphin$ contents. The results are interpreted with regard to the circadian rhythm of beta-endorphin contents, its modification by psychoactive drugs and possible mechanism of diurnal change of opiate receptor in brain.

• Feed Journal
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• v.4 no.7 s.35
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• pp.108-115
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• 2006

우리나라는 사계절이 뚜렷한 기후적 환경으로 여름철 한낮의 외부온도가 35℃ 이상이 되는 날이 계속되고, 야간에도 25℃ 이상인 열대야가 지속되는 날이 많다. 이러한 조건하에서 양돈 생산성 향상을 위해서는 돼지의 사육환경과 성장단계별 적절한 사양기술을 투입하여야만 한다. 돼지는 생리적으로 추위에 의한 영향보다는 여름철 더위에 의한 영향을 쉬게 받으며, 이로 인해 자돈의 쇠약, 압사,수태율 저하, 번식장애 등으로 생산성 저하의 원인이 되며, 사육기간 중에 일시적인 고온스트레스가 돼지가 생존하는 동안 능력의 저하를 초래하게 된다. 특히 하절기 양돈장은 우기와 무더위로 인한 돈사내 온도의 급상승과 더불어 습도의 불균형에 의한 환경적 스트레스로 번식능력과 생산성에 크게 영향을 미칠 수 있으며,돼지에 일시적인 고온 스트레스 피해는 장기간 계속되며, 생존하는 동안 능력저하를 초래하기 때문에 농장별 사육여건에 따른 성장저해 요인을 제거하는 안목이 필요한 계절이다. 즉,5~9월 모돈에 고온스트레스가 가해지면 11~12월, 다음해 1월 모돈의 분만율은 최저가 되고 , 이 시기에 생산된 자돈은 추운겨울을 이겨내야 함으로 육성률도 낮아지며, 이로 인해 4~7월의 출하성적은 최저가 되는 것이다. 따라서 모돈 관리는 5~9월이 집중관리가 필요한 시기이기도 하다. 고온 다습한 환경 하에서 어미돼지는 영양불균형과 생체리듬의 파괴로 인하여 신생자돈의 폐사가 증가할 수도 있고,이유 후 1주일 이내 발정 재귀율이 약 30%정도 감소하고 무발정돈이 많이 발생되며, 수태가 되어도 조기 배아사멸 및 흡수로 인하여 수태율이 25%까지 감소될 수 있다. 현재 국내 양돈농가에는 예년과 같이 돼지 조모성질환의 발생이 늘어나고 있고, 어려움을 겪고 있는 농장이 많은 것으로 조사 보고되어지고 있는데, 이는 농장에 사육되는 돈군이 외부환경에 대한 적응능력과 질병에 저항력이 부족하여 쉽게 질병에 노출되어 발생함으로 농장에는 돼지가 스트레스를 받지 않게 외부 환경과 사양관리 측면에 심혈을 기울려 강건한 축군을 유지하려는 노력이 무엇보다 우선되어져야 한다고 생각된다. 따라서 본고에서는 여름철에 돼지 스트레스를 줄이고 생산성을 향상시키기 위해 돼지의 생리변화와 돈사 급수설비와 사료관리 및 사육관리에 대해 알아보고자 한다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.745-752
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• 2014

This research was conducted to investigate what effect personal relationship personality and temperament have on peer competence of a child. To carry out the research, this experiment subjected 137 preschoolers with age range of 4 to 5 years old attending in 5 education institution for preschoolers in Seoul. The result showed that personal relationship personality of a child and his temperament hold certain influence on peer competence. To take a detailed look on this matter we divided the independent variable into low factors. The result showed that the peer competence was influenced by the introverted personality and outgoing personality which are the sub factors of personality and was also affected by physiological regulation and adaptability which is the sub factor of the temperament.

• Journal of Dairy Science and Biotechnology
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• v.33 no.2
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• pp.119-127
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• 2015

To date, detection of microbial populations in dairy products has been performed using culture media, which is a time-consuming and laborious method. The recently developed chromogenic media could be more rapid and specific than classical culture media. However, the newly developed molecular-based technology can detect microbial populations with greater rapidity and sensitivity than the classical method involving culture media and chromogenic media. This molecular-based technology could provide various options for monitoring the characterization of different states of bacteria and cells. Thus, it could help upgrade the processing system of the dairy industry so as to maintain the safety and quality of dairy foods. Among the various newly developed molecular-based technologies, flow cytometry can potentially be used for monitoring microbiological populations in the dairy industry if official international standards are available for this purpose. When omics technology would have biomarker identification, it could be regarded as the rapid and sensitive analytical methods. Methods based on PCR, which has become a basic technique in microbiological research, can be developed and validated as alternative methods for quantification of dairy microorganisms. This review discusses methods for monitoring microbiological populations in dairy foods and the limitations of these studies, as well as the need for further research on such methods in the dairy industry.

• Journal of Oral Medicine and Pain
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• v.24 no.3
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• pp.245-257
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• 1999

일상 생활에서 우리는 스트레스에 항상 노출되어 있으며, 스트레스는 생체의 신경계, 내분비계 및 면역계의 변화를 수반한 항상성의 파괴로 수많은 정신적, 육체적 질병을 야기시킨다. 특히 구강안면영역에서도 다양한 구강점막질환과 구강건조증 등을 발생시킨다. 스트레스를 제거하는 방법으로는 약물요법 및 상담, 명상요법, 종교요법 등 다양한 방법이 제시되고 있는데, 다소의 부작용이 나타나거나 꾸준히 시행하기가 쉽지 않으며 스트레스의 원인을 근본적으로 제거하기가 현실적으로 용이하지 않은 경우가 많아 스트레스에 대한 해결책에 대하여 많은 관심이 집중되고 있다. 이에 본인은 스트레스가 가해졌을 때 백서 악하선에서 관철되며 apoptosis에 대하여 세포보호작용을 하는 clusterin(SGP-2)을 이용하여 구속스트레스를 가하기에 앞서 오랫동안 경험적으로 사용되어 왔고 부작용이 적은 전통약물인 보혈안신탕을 투여하고 스트레스에 의한 타액선의 조직변화를 관찰하여 그 효과를 확인해 보고자하였다. Sprague-Dawley계 응성 백서(200-230g/bw) 33마리를 정상 대조군(3마리), 구속스트레스군(15마리) 및 보혈안신탕 투여 후 구속스트레스군(15마리)으로 나누고 이틀을 각각 구속장치에 구속한 후 0, 1, 3, 5, 7일에 회생시켜 악하선을 적출하였으며, 면역조직화학법 및 Northern Blot을 이용하여 clusterin의 변화를 관찰하였다. 그 결과는 다음과 같다. 1. 구속스트레스군의 악하선 조직에서 clusterin 단백질과 mRNA는 실험 즉일군에서만 미약하게 관찰되었으며 실험 3일과 5일 후에 핵붕괴 및 핵농축 등의 핵변화를 동반한 apoptosis가 관찰 되었다. 2. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서 실험 5일군까지 clusterin 이 증가한 후 실험 7일군에서는 감소하였다. 3. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서는 apoptosis가 관찰되지 않았다. 4. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서 clusterin mRNA가 실험 전군에 걸쳐 미약하게 관찰되었다. 이상의 결과로 타액선 조직은 스트레스 단백질인 clusterin을 생산하여 세포를 보호함으로써 스트레스 상황에 적응하지만, 생리적 적용한계를 넘는 스트레스에 노출될 때는 apoptosis됨이 확인되었다. 그리고 보혈안신탕은 스트레스 상황에서 세포의 생리적 적응력을 높여 세포의 apoptosis를 억제하는 효과를 나타냄이 확인되었다. 따라서 본 연구결과는 구강건조증등의 스트레스성 타액선 질환의 병리기전을 규명하는데 도움이되리라 생각되며, 향후 항스트레스 효과를 가진 보혈안신탕등의 한약재를 임상에 적용함으로써 스트레스로 인한 신체의 병리적 변화를 다소나마 차단할 수 있을 것으로 사료된다.

• The Journal of the Korea Contents Association
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• v.15 no.8
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• pp.625-641
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• 2015

Recent research shows that emotion is closely related to memory and learning. Although a growing number of educators have high interest in affective aspects of learning processes and outcomes, there are few studies to investigate systematically instructional strategies and learning environments based on learners' emotion. Despite the efforts to understand the role of emotion and to facilitate positive emotion for meaningful learning in face-to-face and online environments, it is still a challenging issue to measure emotion in a valid and reliable way. To implement emotion-based education, it is essential to overcome the limitation of self-report surveys on emotion, which rely on the memory of learners. The current study surveyed emotion measurement tools, which are recently developed in education and other domains, in terms of self-report, neurophysiology, and behavioral responses. This study also discussed how emotion measurement tools can be used in authentic learning and teaching situations. Particularly, this study focused on cutting-edge technologies that would enable educators to collect and analyze learners' emotion easily in real-world contexts. This study will contribute to the research about the role of emotion in education and the design of adaptive learning environments that consider the change of learners' emotion.

• Korean Journal of Agricultural and Forest Meteorology
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• v.15 no.3
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• pp.145-152
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• 2013

This study aimed to investigate the growth and physiological characters of Liriodendron tulipifera seedlings in responses to two different levels of elevated air temperature and $CO_2$ concentration. The seedlings were grown in environment-controlled growth chambers with two combinations of air temperature and $CO_2$ conditions: (1) $22^{\circ}C$ + ambient $CO_2$ $380{\mu}mol\;mol^{-1}$ and (2) $27^{\circ}C$ + $770{\mu}mol\;mol^{-1}$. Physiological characters such as growth, photosynthesis, and water use efficiency, were monitored for 85 days. The seedlings under the elevated treatment showed a greater amount of growth in tree height, compared with those under the control. Regarding the characteristics of assimilatory organs, the elevated treatment resulted in a greater amount of total leaf area, leaf unfolding, and dry weight per leaf area. No significant differences were found in photosynthesis capacity between the two treatments. The increase in water use efficiency with increased intercellular $CO_2$ partial pressure appeared overall lower in the seedling under the elevated treatment, compared with those under the control. The total leaf area of the seedlings under the elevated treatment was larger than that under the control, indicating a higher amount of photosynthesis. In addition, an increase of root growth was noted under the elevated treatment. A resistance mechanism of water stress may be attributed to a higher amount of organ growth as well as the tree height under the elevated treatment than the control.

• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.3
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• pp.383-390
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• 2001

It is a relatively common clinical experience to see a impacted maxillary central incisor Most often, the central incisor is impacted labially. The labial impaction has been indicated as the most difficult to manage. The labial impactions have been found to be associated with mucogingival recession, reduced attached gingiva and periodontal pockets. For the successful treatment, clinicians should avoid loss of attached gingiva in surgical exposure. The most common methods of uncovering labially impacted maxillary anterior teeth are gingivectomy, apically positioned flap and closed eruption technique. If gingivectomy will not leave enough attached gingiva, then an apically positioned flap may be the treatment of choice. If the tooth is impacted in the middle of the alveolus or high in the vestibule near the nasal spine, the closed eruption technique may be the treatment of choice. Closed eruption technique was used in one case, apically positioned flap was used in two case. As the result in two cases of impacted maxillary central incisor, apically positioned flap provide the adequate width of attached gingiva. In case of impacted maxillary central incisor, through the clinical and radiologic examination to select correct surgical operation for reduce the complications.

• Korean journal of applied entomology
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• v.61 no.1
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• pp.129-142
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• 2022

Nutrition dictates nearly all biological processes and determines Darwinian fitness in all living organisms, including insects. Research on insect nutrition has a long history in the field of insect physiology and the importance of understanding insect nutrition has become increasingly apparent with the growing need for producing insects as food and feed. Nevertheless, it is only in recent years that we have witnessed a major breakthrough in our knowledge of insect nutrition. The multivariate, interactive, and dynamic nature of nutrition has long hampered our complete understanding of insect nutrition. However, the challenge posed by such nutritional complexity has been overcome with the advent of the Nutritional Geometry, which is an integrative and multidimensional framework that enabled us to model complex interactions between multiple nutrients. In this review, we introduce the basic concepts and principles of the Nutritional Geometry and describe how this innovative framework has revolutionized the field of insect nutrition and has placed nutrition in the centre of the interface between physiology, ecology, and evolution. We close this review by discussing potentially fertile research areas that can benefit tremendously from the application of this powerful nutritional paradigm in the future.