• Title/Summary/Keyword: 상호작용 기능

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Actin Affinities of Recombinant α-Tropomyosins That Residues 276 or 277 in the Carboxyl Terminal Region are Individually Substituted to a Cysteine Residue (α-트로포마이오신의 276 또는 277 아미노산 잔기가 단일 시스테인 잔기로 치환된 돌연변이 트로포마이오신의 액틴친화력)

  • Kim, Don-Kyu;Cho, Young-Joon
    • Journal of Life Science
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    • v.19 no.5
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    • pp.573-580
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    • 2009
  • It has been previously reported that the carboxyl terminal residues 276 and 277 of ${\alpha}$-tropomyosin are important for actin affinity. In order to investigate actin affinities of these two residues of skeletal (HA) and smooth (QT) muscle ${\alpha}$-tropomyosins, a series of mutant tropomyosins were constructed in which residues at either 276 or 277 were individually replaced with a cysteine residue for chemical modification. These mutants were overexpressed in E. coli as unacetylated and Ala-Ser (AS) dipeptide fusion forms. While actin affinities of unacetylated tropomyosins were considerably low, those of AS/TMs were remarkably higher than those of corresponding unacetylated tropomyosins. However, actin affinities of AS/TM24 (QC) and AS/TM29 (HC) were dramatically lower than those of other AS/TMs and were close to those of unacetylated tropomyosins. In addition, actin affinities of unacetylated TM24 (QC) and TM29 (HC) failed to be restored in the presence of troponin, unlike unacetylated TM10 (HA) and TM23 (CA). These results indicated that the presence of a cysteine residue at 277 caused a drastic decrease in actin affinity, and also that the residue 277 is important for actin affinity of ${\alpha}$-tropomyosin. Since TM23 (CA) showed high actin affinity, it may serve as a valuable tool for chemical modification studies for investigating the interaction of the carboxyl terminal residues of ${\alpha}$-tropomyosin with actin and/or troponin.

An Analysis of the Effect on Using Digital Exhibition of Archives (아카이브의 디지털 전시 활용효과 분석)

  • Choi, Seok-Hyun;Park, Hyun-Suk;Kim, Myoung-Hun;Jeon, Tae-Il
    • Journal of Korean Society of Archives and Records Management
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    • v.13 no.1
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    • pp.7-33
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    • 2013
  • Recently, the development of information technology (IT) continues to promote the digitalization of archives (valuable records) and has therefore, affected archiving centers. This digitalization is shown to these archiving centers by taking advantages of various digital exhibitions. This study aims to consider why it is necessary to use digital exhibitions in archiving centers. In order to examine the needs of digital exhibitions, this study focuses on some ideas and important roles in digital exhibitions and research cases of online exhibitions applied with digital technology. Consequently, this study derives some values from them. Digital exhibitions held online continuously provide the following; first, a great amount of information about the archives by using hyperlink; second, the ability to recreate the attractive contents of digitalized archives by utilizing virtual reality, which makes the users greatly interested; the third and final thing online digital exhibitions provide is the storytelling it provides, which also serves as an avenue for people to communicate with one another. These processes of communication are also reflected in the story. In addition, they can help publicize not only the archiving center, but also the local community as it promotes cultural and tourism resources.

A systematic Review on the Effects of Occupational Reminiscence Therapy in Dementia Offered National Long Term Care Insurance (국내 장기요양보험서비스를 제공 받는 치매 환자 대상 작업 중심 회상치료 효과에 대한 체계적 고찰)

  • Jung, Hae-In
    • Therapeutic Science for Rehabilitation
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    • v.3 no.1
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    • pp.31-37
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    • 2014
  • Objective : The purpose of this study was to look at a systematic review on the effects of occupational reminiscence therapy in Dementia offered National Long term care Insurance. Through this comprehensive study, we have to compare the studies. Methods : We systematically examined papers published in journal from 2009 to 2013, using KERIS. Main words to examine are Dementia, Long term care service, Day care center, reminiscence therapy, occupational centered, etc. Results : 6 studies were selected, All of them were occupational reminiscence therapy. Reminiscence therapy can be devided into communication centered reminiscence therapy and occupational reminiscence therapy. The results demonstrated that the intervention significantly affected the maintenance cognitive skills and reminiscence skills, decreased depression, behavioral changes, improvement of communication and interaction skills and quality of life etc. of elderly people with dementia (p<.05). Conclusions : If occupational therapists can obtain knowledge and make a program for occupational reminiscence therapy, research in this field will be further developed. In the future study, the use of occupational reminiscence therapy applied to a variety of interventions and majority of patients is needed on occupational therapy.

A Study on the Transnational Identity of Diaspora and Diversity (디아스포라의 초국적 정체성과 다양성에 관한 고찰)

  • Yim, Young-Eon;Kim, Han-Soo
    • Korea and Global Affairs
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    • v.1 no.2
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    • pp.109-128
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    • 2017
  • The purpose of this study is to consider the appearance of the global generation transnational identity and forming process, existence aspect, functional role, and on the actuating mechanism, and etc. The results about the transnational identity of Diaspora and diversity are as follows. First, as to the transnational identity, the emigrants had been being determined by the relation with the accreditation and how type had been deal with one's decision about the self-identify. Second, the individual experience of the emigrant, interaction, and unstable status political support etc. various factors were combined and the diversity of the Diaspora identity showed. Third, the identity concept had been performing the function in the more expanded meaning called the nation and nation through the continuous meaning expansion than the individual as the national ideology. Fourth, the transnational identity of Korean-Chinese was specialized into the nation identity, double identity, and 'the identity of the third' etc. Fifth, the transnational identity of the Nikkei-Brazilian appeared for Japanese identity, Brazilian identity, and Nikkeijin identity etc. in Japan. In conclusion, the Transnational identity of the Diaspora is reproducing the identity of the emigrant, it suggests through the differentiation in the settlement and exclusion.

The Effects of Merchandise Display on Distributor's Merchandise Selection -Focused on Multi-Level Marketing Company- (상품진열이 중간의 상품선택에 미치는 영향 -다단계 판매회사의 생필품 매장들 중심으로-)

  • Ahn, Gill-Sang;Yoon, Tae-Joong
    • Journal of Distribution Research
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    • v.10 no.1
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    • pp.33-57
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    • 2005
  • After 1990's, many multi-level marketing companies lave been introduced in Korea. These MLM companies operate their stores as same way as general retailing stores. The major characteristics of these MLM companys' store is that their main customers are distributors who sell the purchased merchandise to another customers. Many studies about merchandise display in general retailing stores were reported. But, there was less research about merchandise display in these special type stores such as MLM companys' stores. This paper investigates the effects of merchandise display on distributor's merchandise selection in channel flow of multi-level marketing company. For this purpose, we formulated four hypotheses about display variance in quantity, height, location, and related merchandise to analyze the effect of merchandise display methods in MLM companys' stores. The experiment had been proceeded in three stores in a MLM company for 6 weeks and the sales data were collected by POS. The methods to analyze the data were used ANOVA and T-test. Findings of this study are as follows; First, there was no effect to store sale by the interaction effect between merchandise display method and scale of store. Second, scale of store affected considerably the volume of sales of each store according to main effect analysis. Third, display variance in quantity, height, and location did not affect store sale. In the related merchandise display, however, sale in all store was increased. Fourth, in additional analysis considering merchandise display only, display variance in both height and location affected their sale in large scale store. Based on the above results, we may predict merchandise display can affect sale in MLM companys' store as well as general retailing stores. Therefore if MLM company has large scale store, it should consider merchandise display methods in its stores.

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LFH: Low-Cost and Fast Handoff Scheme in Proxy Mobile IPv6 Networks with Multicasting Support (프록시 모바일 IPv6 네트워크에서 멀티캐스팅을 지원하는 저비용의 빠른 이동성관리 기법)

  • Kim, Eunhwa;Jeong, Jongpil
    • KIPS Transactions on Computer and Communication Systems
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    • v.2 no.6
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    • pp.265-278
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    • 2013
  • With the recent advancements in various wireless communication technologies, the importance of mobile multicasting is coming to the fore, in an effort to use network resources more efficiently. In the past, when various mobile IP-based multicast techniques were proposed, the focus was put on the costs needed for network delivery for providing multicast services, as well as on minimizing the multicast handover delay. For techniques using MIPv6 (Mobile IPv6), a host-based mobility management protocol, however, it is fundamentally difficult to resolve the problems of handover delay and tunnel convergence. To resolve these problems, a network-based mobility management protocol called PMIPv6 (Proxy Mobile IPv6) was standardized. Although performance is improved in PMIPv6 over MIPv6, it still suffers from the problems of handover delay and tunnel convergence. In this paper, to overcome these limitations, a technique called LFH (Low-cost and Fast Handoff) is proposed for fast and low-cost mobility management with multicasting support in PMIPv6 networks. To reduce the interactions between the complex multicast routing protocol and the multicast messages, a simplified proxy method called MLD (Multicast Listener Discovery) is implemented and modified. Furthermore, a TCR (Tunnel Combination and Reconstruction) algorithm was used in the multicast handover procedure within the LMA (Local Mobility Anchor) domain, as well as in the multicast handover procedure between domains, in order to overcome the problem of tunnel convergence. As a result, it was found that LFH has reduced multicast delay compared to other types of multicast techniques, and that it requires lower costs as well.

P2P Streaming Method for QoS-sensitive Multimedia Multicast Applications (QoS에 민감한 멀티미디어 멀티캐스트 응용을 위한 P2P 스트리밍 기법)

  • Park, Seung-Chul
    • The Journal of the Korea Contents Association
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    • v.10 no.9
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    • pp.68-78
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    • 2010
  • As the IP multicast function is very slowly deployed in Internet due to its scalability problem and inter-domain interoperability problem, interest in the P2P(Peer-to-Peer) streaming technologies for the realtime multimedia multicast applications such as IPTV is highly growing. This paper proposes a P2P streaming method for the QoS-sensitive multimedia multicast applications such as highly-interactive personal IPTV and video conferences. The proposed P2P streaming method allows an application to construct a reliable streaming tree in which a proper number of backup peers are placed according to its reliability requirement. The reliable streaming tree reduces the reconnection delay, occurred in the case of a normal and/or abnormal peer leave, so as to minimize the loss of streaming data. In the proposed P2P streaming method, the join delay of a peer called startup delay is also substantially reduced because the bandwidth and end-to-end delay information of every peer kept in a distributed way allows the target peer for a joining peer to be able to be quickly determined. Moreover, the proposed method's peer admission control mechanism based on the bandwidth and end-to-end delay enables the delay-bounded streaming services to be provided for its corresponding applications.

Neural Basis Involved in the Interference Effects During Dual Task: Interaction Between Calculation and Memory Retrieval (이중과제 수행시의 간섭효과에 수반되는 신경기반: 산술연산과 기억인출간의 상호작용)

  • Lee, Byeong-Taek;Lee, Kyoung-Min
    • Korean Journal of Cognitive Science
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    • v.18 no.2
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    • pp.159-178
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    • 2007
  • Lee & Kang (2002) showed that simultaneous phonological rehearsal significantly delayed the performance of multiplication but not subtraction, whereas holding an image in the memory delayed subtraction but not multiplication. This result indicated that arithmetic function is related to working memory in a subsystem-specific manner. The aim of the current study was to examine the neural correlates of previous finding using fMRI. For this goal, dual task conditions that required suppression or no suppression were manipulated. In general, several areas were more activated in the interference conditions than in the less interference conditions, although both conditions were dual condition. More important finding is that the specific areas activated in the phonological suppression rendition were right inferior frontal gyrus, left angular, and inferior parietal lobule, while the areas activated in the other condition were mainly in the right superior temporal gyrus and anterior cingulate gyrus. Furthermore, the areas activated in the phonological or visual less suppression condition were right medial frontal gyrus, left middle frontal gyrus, and bilateral medial frontal gyri, anterior cingulate cortices, and parahippocampal gyri, respectively. These results revealed that sharing the processing code invokes interference, and its neural basis.

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A study to contribute to a philosophy of nursing education in Korea (한국 간호교육의 이념 정립을 위한 기초조사)

  • Ha Y.S;Han Y.B
    • The Korean Nurse
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    • v.15 no.6 s.86
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    • pp.42-60
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    • 1976
  • 1.행동특성별 제언 1 기본 지식면 첫째, 간호원리, 법칙에 관한 지식을 갖게 한다. 둘째, 간호학의 용어, 기호, 단어 및 개념에 대한 지식을 갖게 한다. 셋째, 간호원리, 의견, 활동을 검증하고 판단하는 기준에 관한 지식을 갖게 한다. 넷째, 간호현상의 과정, 경향, 원인, 순서에 관한 지식을 갖게 한다. 다섯째, 간호문제 요구를 처리하는데 필요한 수단 형식, 체제, 용법에 관한 지식을 갖게 한다. 여섯째, 학설에 관한 지식을 갖게 한다. 일곱째, 간호학 분야에서의 특수한 문제나 현상을 다루는데 쓰이는 탐구방법에 관한 지식을 갖게 한다. 여덟째, 간호 문제나 자료의 분류에 관한 지식을 갖게 한다. 아홉째, 특수한 사실의 성질, 특징, 정확성에 관한 지식을 갖게 한다. 제언 2 이해능력면 첫째, 간호문제를 창조적으로 해결하고 연구, 발전 시킬 수 있는 능력을 기른다. 둘째 간호현상을 정확하게 추리하고 검증하여 결론을 추출하며 진술하는 능력을 기른다. 셋째, 간호문제를 해석하고 자료를 재정리, 재배열, 또한 새로운 견지에서 해설하는 능력을 기른다. 넷째, 관찰된 간호현상을 설문화 또는 도표화 하는 능력을 기른다. 제언 3 태도면 첫째, 정서적 안정감을 유지하면서 환자와의 인간 관계를 원만하게 유지할 수 있는 태도를 기른다. 둘째, 확신을 갖고 간호활동에 임하는 태도를 기른다. 셋째, 한국사회가 필요로 하는 간호원의 역할을 스스로 감지 적응하고 간호활동 개선에 이바지하는 태도를 기른다. 넷째, 약품을 신중히 다루는 태도를 기른다. 다섯째, 새로운 직을 배워 개척하고자 하는 의욕을 갖게 한다. 제언 4 기능면 첫째, 환자를 이해하고 안정시킬 수 있는 능력을 갖게 한다. 둘째, 간호를 포괄적으로 수행할 수 있는 능력을 기른다. 셋째, 간호문제를 창의적으로 처리할 수 있는 능력을 기른다. 넷째, 새로운 간호지식이나 기술에 대해서 자율적으로 연수, 학습할 수 있는 능력을 기른다. 다섯째, 간호 문제에 대한 흥미와 호기심을 갖게 한다. 여섯째, 병실기구를 과학적이고 합리적으로 관리하는 기능을 기른다. 일곱째, 의료(진료)기구를 조작할 수 있는 능력을 기른다. 제언5 비판능력면 첫째, 간호문제나 현상 방법에 있어서 그 가치를 논리적 또는 주관적 기준에 의해 자료를 평가하는 능력을 기른다. 둘째, 일반적인 이론, 학설, 표준 사실에 입각해서 자료를 평가할 수 있는 능력을 기른다. 제언 6 분석능력면 첫째, 요소 및 부분들간의 관련과 상호작용 또는 인간관계를 관찰하고 분석할 수 있는 능력을 기른다. 둘째, 복잡한 간호문제를 부문별, 요소별로 분석하는 능력을 기른다. 셋째, 자료의 형태, 구조, 형식의 특징과 조직을 분석하는 능력을 기른다. 제언 7 종합 능력면 첫째, 간호계획 절차를 창안할 수 있는 능력을 기른다. 둘째, 자기의 생각을 효율적으로 전달하는 능력을 기른다. 셋째, 특수한 간호 현상이나 기본적 명제에서 어떤 추상적 관계를 연역해 낼 수 있는 능력을 기른다. 제언 8 응용능력면 첫째, 간호문제를 해결하는데 실제로 응용 할 수 있는 교육을 시킨다. 둘째, 간호이론을 구체적인 상황에 효율적으로 응용할 수 있는 능력을 기른다. 셋째, 지역사회의 특성에 알맞은 간호기술이나 간호절차를 창안할 수 있는 능력을 기른다. 넷째, 간호방법을 모색하고 이용하는 능력을 기른다. 다섯째, 조사를 통해 합리적이고 논리적인 결론을 내릴 수 있는 능력을 기른다.

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Exploring the Meaning of Outdoor Play Spaces Perceived by Young Children and Early Childhood Teachers (유아와 교사가 인식하는 유아교육기관 바깥놀이 공간의 의미 탐색)

  • Kwon, Sun-Young;Jung, Ji-Hyun;Park, Sun-Mi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.1
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    • pp.85-94
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    • 2017
  • This study researched the meaning of the outdoor play spaces used by young children, as perceived by them and their teachers. For this purpose, indirect observation, nonformal interviews during the activity of young children and in-depth interviews with teachers were conducted in 3 kindergartens and 1 day care center which operate various programs. As a result, outdoor play spaces were recognized as a psychological space, expanded space and sequential space for the relationships of young children. Meanwhile, early childhood teachers perceived them as a functional space, expanded space and restricted space of the children's daily lives. It was recognized that outdoor play spaces provided the children with good and unstructured environments to reorganize their own daily pattern through expanded play and the chance to naturally form peer relationships. This suggests that the space configuration which is most suitable for child centered development is one that is formed within and by their daily lives, rather than the standardized configuration of outdoor play spaces.