• Journal of Korean Society of Disaster and Security
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• v.16 no.2
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• pp.85-98
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• 2023

Flood is one of the most frequent natural disasters worldwide. In Korea, the probability of urban flooding is greatly increasing due to complex factors such as global warming, an increase in impervious areas, and limitations in expanding water supply facilities in existing urban areas. However, large-scale civil engineering works to prevent urban inundation are socially and economically difficult to obtain national consent. Recently the importance of resilience, which is the ability to return to the original state after a disaster through rapid recovery while preparing for natural disasters to a level that the local community can afford socially and economically, is increasing. Accordingly, various studies on urban resilience have been conducted, but the resilience measurement method related to the lifeline that provides essential services of the city is insufficient. However, among lifelines, road networks are important facilities for the transportation of recovery resources and rapid recovery in the event of a natural disaster, so road networks are a major factor that must be considered when measuring the degree of recovery of a city in the field of natural disasters. Therefore, this study proposes a recovery evaluation method considering the characteristics of resilience and road networks in the urban flooding field and analyzes the effect of road networks on urban resilience.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.25-25
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• 2022

피부 노화는 피부와 피부 지지층 등의 광범위한 퇴행 과정을 말한다. 피부 노화의 원인은 흡연, 공해, 스트레스 등이 있지만, 그 중에서도 자외선(ultra violet, UV) 조사가 가장 큰 요인으로 꼽힌다. 반복적인 자외선 조사에 의해 진행되는 피부노화를 광노화라고 하며 그 가장 큰 특징으로는 콜라겐 섬유와 엘라스틴의 감소로 야기되는 주름을 들 수 있다. 본 연구에서는 제주에서 채집한 바위수국의 추출물 및 분획물의 항산화 및 자외선으로 인한 피부노화 예방(anti-photoaging) 효능을 확인하고, 활성물질을 분리하여 광노화 예방 효능과 그 메커니즘을 확인하였다. 실험에 사용된 바위수국은 범의귀과의 덩굴성 식물로 바위면이나 나무줄기 등에 붙어서 자라며, 한국(제주, 울릉도)과 일본에 분포한다. 바위수국 추출물과 분획물에서 총 페놀 함량. 총 플라보이드 함량, DPPH 및 ABTS 라디칼소거 활성의 항산화 실험 결과, 부탄올과 에틸아세테이트 분획층에서 강력한 항산화 활성이 관찰되었다. 또한 UVA를 조사한 인간 진피 섬유아세포 (human dermal fibroblast, HDF)데 대한 콜라겐 분해효소인 matrix metalloproteinase-1(MMP-1) 생성 억제 활성을 확인한 결과, 부탄올 분획층이 세포 생장 저해 없이 가장 우수한 효능이 확인되었다. 따라서 부탄올 분획층에서 주요 성분 분리 실험을 수행하여 총 4개의 화합물을 분리하였다; Chlorogenic acid (1), Quercetin-3-O-glucosyl-(1-2)-rhamnoside (2), Quercetin-3-O-xylosyl-(1-2)-rhamnoside (3), Quercitrin (4). 분리한 4개의 물질의 MMP-1 생성 억제 활성을 비교한 결과 화합물 2가 세포독성 없이 MMP-1 생성 억제 효능이 우수하였고, 이후 화합물 2의 광노화 예방 효능과 그 메커니즘을 확인하였다. 화합물 2는 MMP-1의 생성을 억제할 뿐만 아니라 procollagen type I의 생성을 증가시켰으며, MMP-1 생성에 관여하는 mitogen-activated protein kinase (MAPK)/activator protein-1 (AP-1) 신호전달경로를 하향 조절하며, 콜라겐 생성과 관련된 Transforming growth factor-β (TGF-β)/Smad 신호전달경로를 상향 조절하여 UVA에 의한 광노화 예방에 효능을 나타내었다. 이러한 결과들을 바탕으로, 바위수국은 항노화(anti-aging) 기능성 화장품 및 이너뷰티 기능성 식품 소재로 개발이 가능할 것으로 기대된다.

• Journal of Life Science
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• v.33 no.11
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• pp.859-867
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• 2023

Lupeol is a type of pentacyclic triterpene that has been reported to have therapeutic effects for treating many diseases; however, its effect on insulin resistance is unclear clear. This study examined the inhibitory effect of lupeol on the serine phosphorylation of insulin receptor substrate-1 in insulin resistance-induced 3T3-L1 adipocytes. 3T3-L1 cells were cultured and treated with tumor necrosis factor-α (TNF-α) for 24 hours to induce insulin resistance. Cells treated with different concentrations of lupeol (15 μM or 30 μM) or 100 nM of rosiglitazone were incubated. Then, lysed cells underwent western blotting. Lupeol exhibited a positive effect on the negative regulator of insulin signaling and inflammation-activated protein kinase caused by TNF-α in adipocytes. Lupeol inhibited the activation of protein tyrosine phosphatase-1B (PTP-1B)-a negative regulator of insulin signaling-and c-Jun N-terminal kinase (JNK); it was also an inhibitor of nuclear factor kappa-B kinase (IKK) and inflammation-activated protein kinases. In addition, Lupeol downregulated serine phosphorylation and upregulated tyrosine phosphorylation in insulin receptor substrate-1. Then, the downregulated phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway was activated, the translocation of glucose transporter type 4 was stimulated to the cell membrane, and intracellular glucose uptake increased in the insulin resistance-induced 3T3-L1 adipocytes. Lupeol may improve TNF-α-induced insulin resistance by downregulating the serine phosphorylation of insulin receptor substrate 1 by inhibiting negative regulators of insulin signaling and inflammation-activated protein kinases in 3T3-L1 adipocytes.

• Korean Journal of Remote Sensing
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• v.39 no.6_3
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• pp.1747-1761
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• 2023

Wetlands, defined as lands periodically inundated or exposed during the year, are crucial for sustaining biodiversity and filtering environmental pollutants. The importance of mapping and monitoring their topographical changes is therefore paramount. This study focuses on the topographical variations at the Incheon River estuary wetland post-restoration, noting a lack of adequate prior measurements. Using a multi-temporal Sentinel-1 dataset from October 2014 to March 2023, we mapped long-term variations in water bodies and detected topographical change anomalies using a pixel-frequency approach. Our analysis, based on 196 Sentinel-1 acquisitions from an ascending orbit, revealed significant topography changes. Since 2020, employing the pixel-frequency technique, we observed area increases of +0.0195, 0.0016, 0.0075, and 0.0163 km² in water level sections at depths of 2-3 m, 1-2 m, 0-1 m, and less than 0 m, respectively. These findings underscore the effectiveness of the wetland restoration efforts in the area.

• Korean Journal of Environment and Ecology
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• v.38 no.1
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• pp.67-78
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• 2024

The term ecosystem services refers to natural ecosystems' benefits to humans. Various models have been developed and applied to quantify ecosystem services. Habitat quality assessment is a widely used leading InVEST ecosystem service model. In Korea, habitat quality assessment is conducted for national parks. For habitat quality assessment, the initial value of habitat quality must be used to assess the sensitivity to threats, which varies depending on the country and application field. Therefore, an expert survey (AHP) was conducted based on previous habitat quality assessments in national parks to adjust the sensitivity, the initial value for the habit quality assessment. As a result of the AHP, 18 items were adjusted, including 10 items, such as natural grassland and unarranged fields, upward and 8 items, such as rivers and ponds, downward. Based on the adjusted sensitivity results, the habitat quality of Bukhansan National Park and Gyeryongsan National Park (urban type), Gyeongju National Park (historic type), Hallyeohaesang National Park (ocean type), and Jirisan National Park and Seoraksan National Park (mountain type) were adjusted. The results of the analysis showed that the habitat quality of urban dry areas and water bodies distributed in the national parks was reflected in the habitat quality assessment. In the future, it will be possible to evaluate the habitat quality of natural parks using this standard.

• Industry Promotion Research
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• v.9 no.2
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• pp.29-35
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• 2024

Recently, the Korean financial market has implemented a ban on unleveraged short selling, and leveraged short selling, which involves selling borrowed securities, is called general short selling. This study sought to come up with improvement measures to revitalize short selling from the perspective of individual investors. Short selling refers to selling stocks you do not own in the stock market, predicting that the stock price of the stock will fall, and borrowing stocks to sell them. Based on the results of this study, the short selling market's growth and improvement plans are as follows. First, a plan must be developed to expand short selling opportunities for individual investors. In the domestic short selling market, including KOSPI and KOSDAQ, foreign and institutional participants account for more than 95% of the market, and individual investors are very small. Therefore, its expansion is inevitable. Second, monitoring and punishment for unfair short selling transactions must be strengthened. Representative improvement measures that can minimize the side effects of short selling include strengthening monitoring of unfair trading and short selling, and raising the level of punishment. In addition, measures must be taken to further increase the level of punishment for short selling related to unfair transactions. Third, the short selling reporting and disclosure system needs to be improved. In the case of Korea, short selling transactions are not yet as active as in developed countries, but there is a need to expand the disclosure system to strengthen market transparency in preparation for future short selling transactions becoming more active. In conclusion, it is reported that if short selling regulations are excessively strengthened, losses may occur in terms of price efficiency and market liquidity, which may ultimately have a negative impact on the market. Therefore, policies related to short selling must be made while taking into account the positive aspects of regulatory effects and the negative impact on the market.

• Industry Promotion Research
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• v.9 no.1
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• pp.159-166
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• 2024

This study studied the life experiences of story grandmother activities on the meaning of a happy life and positive growth for the elderly through phenomenology. This study period was conducted with pre-interviews from March 2021, and research was conducted until July 2022. As for the research method, 9 elderly women were selected as a Colaizzi phenomenological research method suitable for the work of exploring and understanding life as it is, and the following conclusions were drawn. First, the happiness experience of the elderly provides a life that responds to positive changes, gives positive meaning, and actively discovers in a desire-ful life, a comparative life, and a adaptation and coping happy life. Second, the elderly experienced the meaning of life by experiencing the happiness of moments in the self-realized life of the upward · downward theory. Third, the growth of the elderly is a happy change in PERMAS of positive psychology, pursuing life with positive emotions, immersion, and positively related meaning and purpose of life, and growing while looking at life with achievement and strength. Since this study targets elderly women aged 65 or older who are engaged in story grandmother activities, there is a limit to generalizing the research results, so it is suggested to study the growth process of more diverse age groups and various types of volunteer activities in the future.

• Microbiology and Biotechnology Letters
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• v.51 no.4
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• pp.517-525
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• 2023

The emergence and spread of multidrug-resistant Pseudomonas aeruginosa (MRPA) have become a serious problem worldwide. The involvement of metallo-β-lactamases (MBLs) in inducing carbapenem resistance is particularly acute. However, unlike other members of the Enterobacteriaceae genus, new clones of P. aeruginosa are constantly emerging and rapidly replacing previously prevalent dominant clones. Therefore, this study aimed to perform antimicrobial resistance gene analysis, integron gene cassette analysis using DNA sequencing, and plasmid transfer analysis by conjugation to investigate the antimicrobial resistance dynamics of 18 P. aeruginosa strains isolated from various medical samples at a general hospital in Busan from September 2017 to September 2019. All 18 strains showed extensively drug-resistant (XDR) phenotype and were resistant to most antibiotics, except colistin (100%) but were susceptible to aztreonam (22.2%) and ceftazidime (16.6%). Approximately 66.7% of the strains had Class 1 integrons showing various antimicrobial resistances. Notably, IMP-6 ST235 (66.7%), VIM-2 ST357 (16.7%), and IMP-1 ST446(16.7%) were identified. The identification of IMP-1-producing ST446, previously unreported in Korea, is noteworthy considering the emergence and prevalence of another MRPA high-risk clone.

• Journal of Korean Library and Information Science Society
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• v.55 no.1
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• pp.123-143
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• 2024

In this study, we analyzed the trends in staffing changes in academic libraries over the past ten years and surveyed staff working there to assess their perceptions of staffing levels and the current criteria for staffing allocation in academic libraries. We utilized statistical data from academic libraries to analyze staffing changes from 2014 to 2023. The survey was conducted through an online questionnaire targeting library staff, and responses from 216 respondents from 4-year universities and junior colleges were analyzed. The analysis of staffing changes revealed a decrease in the average number of employees in large 4-year universities and junior colleges, with a decrease in regular positions and an increase in non-regular positions. Survey results suggest causes such as declining school-age population and admissions quotas, budget shortages in universities, and structural adjustments. The perception of staff from 4-year universities and junior colleges regarding the criteria for staffing allocation was mainly negative, suggesting improvements such as increasing and refining criteria numbers, specifying standards for full-time librarians, clarifying criteria for compliance, and enhancing enforcement of standards. The results of this study can enhance understanding of staffing situations in academic libraries and serve as fundamental data for improving staffing criteria in the future, based on an understanding of librarians' perceptions on the ground.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.2
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• pp.157-164
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• 2024

In 2020, 24,000 TEU ultra-large container ships began arriving at the Busan New Port. In this study, the wind pressure and hydraulic force acting on the hull were calculated to obtain the horsepower required for the tugboats for safe berthing and unberthing of a 24,000 TEU ultra-large container ship at the Busan New Port. When the wind speed is 10 m/s (20 kts), 13,000 TEU container ships meet the tug horsepower standard of the current Busan port tugboat operation rules, but 16,000 TEU and 24,000 TEU container ships do not satisfy the regulations. Therefore, it was proposed to raise the standards for tugboat use by dividing the size of ships of "G/T 150,000 tons or more," which is the largest vessel under the current tugboat use standards, into two stages. Because 140,000 tons requires 12,100 horsepower, 170,000 tons requires 14,500 horsepower, and 230,000 tons requires 18,000 horsepower, the study proposed 16,000 horsepower for 150,000 to less than 200,000 tons and 18,000 horsepower for 200,000 tons or more for the use of tugboats.