• Journal of Advanced Marine Engineering and Technology
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• v.32 no.5
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• pp.684-690
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• 2008

In most engineering applications related with the heat conduction phenomena, a conventional Fourier heat conduction equation has been successfully applied and it has supplied quite reasonable results. However, it is well known that the Fourier heat conduction equation is failed in the application to the extremely small space and short time, in other words, a nano-scale system and a pico-second time. In this study, non-Fourier effect was evaluated in the heat conduction by considering the concept of a phase lag model. The results show the existence of a heat wave, which means that the heat is transferred with a finite speed while an infinite speed of heat transfer is assumed in the conventional Fourier heat conduction. In addition, the copper and the gold are tested to evaluate the phase lag time between the heat flux and the temperature gradient. The results show that the gold has the heat wave speed faster than that of the copper consistent with the prediction based on an actual experiment.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.1661-1664
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• 2013

본 연구는 만성 뇌졸중 환자 5 명을 대상으로 상지 운동(Affected hand의 주먹 쥐기/펴기운동)시 참가자의 운동의지와 운동 수행의 유무에 따라 차이가 있을 것을 가정하고, 운동 수행 및 운동의지가 존재하는 Active movement와 운동 수행을 하지만 운동의지가 없는 Passive movement, 운동 수행은 없지만 운동의지가 있는 Motor Imagery(MI)의 세가지 task에 따른 뇌파의 연결성을 비교하고자 한다. 이 때 EEG 영역 간의 연결성을 보기 위한 분석 방식 중 하나인 Phase locking value(PLV)를 통해 각 task 간의 차이를 비교 및 분석했다. 운동 수행은 동일하지만 운동의지 유무에 따른 차이는 Passive movement가 전반적으로 뇌 영역간 연결이 감소하고 Active movement가 motor task 시작 후 375ms를 기점으로 급격히 증가함을 보이는 데에서 발견할 수 있었으며, 운동 수행 유무에 따른 차이는 687.5ms 이후 Active movement에 비해 MI에서 뇌 영역 간 연결 수가 확연히 감소하는 데에서 큰 차이를 나타내었다. 이에 따라 본 연구에서는 만성 뇌졸중 환자의 상지운동 시의 motor task에 따른 EEG 영역간의 연결성을 토대로 운동의지 검출이 가능성이 있음을 밝혔다.

• The Transactions of the Korean Institute of Power Electronics
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• v.10 no.4
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• pp.323-330
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• 2005

In order to increase reliability and reduce system cost, this paper studies particularly applicable method for sensorless PM BLDCM drive system. The waveform of the motor internal voltages(or back emf) contains a fundamental and higher order frequency harmonics. Therefore the third harmonic component is extracted from the stator phase voltage. The resulting third harmonic signal keeps a constant phase relationship with the rotor flux for any motor speed and load condition, and is practically free of noise that can be introduced by the inverter switching, making this a robust sensing method. In addition, a simple starting method and a speed estimation approach are also proposed. Some experimental results are Provided to demonstrate the validity of the proposed control method.

• The Korean Journal of Food And Nutrition
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• v.14 no.6
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• pp.568-572
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• 2001

To screen antioxidative and whitening effects of some medicinal plants, 70% ethanol extracts were tested for their electron donating abilities to DPPH ( ${\alpha}$, ${\alpha}$-diphenyl- ${\beta}$-picrylhydrazyl) and inhibitory activities against lipid peroxidation, and tyrosinase inhibition in vitro. The electron donating activities of 70% ethanol extracts at the concentration of 100 $\mu\textrm{g}$/ml were in the order of Forsythiae fructus > Polyporaceae > Glycyrrhizae radix > Schizandrae fructus > Ramulus mori > Carthami semen. The order was Forsythiae fructus > Carthami semen > Schizandrae fructus > Polyporaceae > Glycyrrhizae radix when tested at 10 $\mu\textrm{g}$/ml, indicating that the activities depend on the concentration. The electron donating activities of Forsythiae fructus and Carthami semen at the concentration of 1 $\mu\textrm{g}$/ml were 37% and 31% respectively. Lipid peroxidation inhibitory activities were in the order of Artemisia messerschimidtiana > Glycyrrhizae uadix > Rehmaniae radix > Ramulus mori. Tyrosinase inhibitory activities were in the order of Ramulus mori > Artemisia messerschimidtiana > Oyster mushroom. The results suggest that Forsythiae fructus, Artemisia messerschimidtiana and Ramulus mori could be used as materials for anti-skin aging functional cosmetics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.429-439
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• 2020

This study examined the effect size of virtual reality programs on the upper extremity function of stroke patients through a meta-analysis. Databases, such as the Research Information Sharing Service, the Korean Studies Information Service System, the National Library of Korea, the Korean Citation Index, and the National Digital Science Library, were used. Previous articles were surveyed for virtual reality programs between January 2010 and June 2019. A meta-analysis was performed by selecting the final 14 studies based on the PICO standard. The RoB and RoBANS tools were used as quality assessment tools for randomized and non-randomized control trials, respectively. The CMA 3.0 program was used to calculate the effect size of each study. Sub-group analysis, meta-regression analysis, and publication bias were performed. The total effect size of the virtual reality programs on the upper extremity function was Hedges's g=0.390 (95% CI: 0.192~0.587) (p<.05). The virtual reality program positively affects the upper extremity function of stroke patients. Therefore, the development of various virtual reality programs and industry-academia cooperation technology for stroke patients is required in accordance with the fourth industry. Randomized control trials and detailed upper extremity function studies for virtual reality programs will be needed in follow-up studies.

• Journal of Society of Preventive Korean Medicine
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• v.28 no.2
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• pp.131-150
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• 2024

Objectives : The aim of this study was to perform network analysis and analysis using the K-HERB database on inflammatory bowel disease (IBD), to verify the similarity between the derived networks and existing prescriptions, and to explore the possibility of developing new IBD prescriptions preliminarily. Methods : We conducted a comprehensive literature search on July 6, 2024, utilizing databases such as ScienceON, RISS, and OASIS. Clinical studies assessing the efficacy of herbal medicine in treating Crohn's disease and ulcerative colitis were identified and compiled into a structured database. This dataset, which included related prescriptions and herbal formulations, was subsequently analyzed using NetMiner 4 for centrality and Louvain clustering analyses. We then compared the networks derived from the K-HERB database with existing therapeutic prescriptions to assess their similarity. Results : A total of 24 prescriptions and 66 herbs were identified across the surveyed studies on IBD. Paeoniae Radix Alba(白芍藥) emerged as the most frequently utilized herb for both Crohn's disease and ulcerative colitis. Prominent herb combinations included Paeoniae Radix Alba-Angelicae Sinensis Radix (白芍藥-當歸), Angelicae Sinensis Radix-Coptidis Rhizoma (當歸-黃連), and Coptidis Rhizoma-Scutellariae Radix (黃連-黃芩) for ulcerative colitis. Centrality analysis revealed that Poria cocos (茯苓) and Paeoniae Radix Alba (白芍藥) had high centrality in the Crohn's disease, while Angelicae Sinensis Radix (當歸) and Paeoniae Radix Alba (白芍藥) had high centrality in the ulcerative colitis, indicating their prominent roles within the networks. Cohesion analysis resulted in 7 networks for Crohn's disease and 16 networks for ulcerative colitis. After excluding networks with a single herb, three networks related to Crohn's disease and two related to ulcerative colitis were examined using the K-HERB database. Among the 14 derived prescriptions for Crohn's disease and seven for ulcerative colitis, all except Oryeong-san (五苓散) were non-traditional in the context of IBD treatment. Conclusion : This preliminary study may provide a basis for the understanding and application of herbal prescriptions for IBD based on network analysis and the K-HERB database.

• The Korea Journal of Herbology
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• v.37 no.5
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• pp.89-96
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• 2022

Objectives : This research was performed to analyze the components in the different parts of Lythrum salicaria L. and to compare which parts of L. salicaria L. are appropriate for food development. Methods : L. salicaria L. was extracted in 20% EtOH at 100 ℃ for 4 hours. Cytotoxicity was investigated in 3T3-L1 cells after treatment of 10-500 ㎍/ml L. salicaria L. for 24 hours. Total polyphenol content (TPC) was estimated using 1 N Folin-ciocateu reagent. 2,2-Diphenyl-1-picryhydrazyl (DPPH) radical scavenging activity was estimated using DPPH reagent and gallic acid. The chemical composition was analyzed by high-performance liquid chromatography (HPLC). 1) Results : The half maximal inhibitory concentration (IC50) in the extracts of the whole plant, aerial parts, and root parts was 350 ㎍/ml, over 500 ㎍/ml, and 150 ㎍/ml, respectively. The TPC in the extracts of the whole plant, aerial parts, and root parts was 527.1 mg/g, 422.6 mg/g, and 781.1 mg/g, respectively. The averages of vitexin contents in the aerial parts, and root parts were 256.7 ± 154.9 ㎍/g and 266.1 ± 63.2 ㎍/g, respectively. The averages of TPC in the leaves, roots, flower stalks and stems were 224.0 ± 53.7 tannin acid (TA) mg/g, 221.8 ± 70.2 TA mg/g, 249.8 ± 34.4 TA mg/g, and 67.7±8.9 TA mg/g, respectively. The averages of DPPH radical scavenging activity in the leaves, roots, flower stalks, and stems were 282.01 ± 43.3 gallic acid equivalent (GAE) 𝜇mole/g, 260.16 ± 44.1 GAE 𝜇mole/g, 288.0 ± 9.3 GAE 𝜇mole/g, and 97.6 ± 10.7 GAE 𝜇mole/g, respectively. Conclusions : There were no significant differences in the content of components or antioxidant activity in the aerial parts compared to those in the whole plant of L. salicaria L. Furthermore, the root parts had low extract yield, cytotoxicity, and quality control problems, therefore our results suggest that the use of the aerial part of L. salicaria L. would be the most appropriate for food development.

• Journal of Nutrition and Health
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• v.49 no.1
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• pp.18-27
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• 2016

Purpose: Our previous study demonstrated the hypoglycemic effects of mulberry (Morus alba L.) leaf and the underlying mechanisms. Here we explored the potency of mulberry twigs (TW) and root barks (RB) in postprandial hypoglycemic effects in vitro and in vivo. Methods: The major components of TW and RB were determined by high performance liquid chromatography (HPLC). Alpha-glucosidase inhibition and glucose/fructose uptake inhibition in Caco-2 cells were determined for TW, RB, and their major components, followed by an oral sugar tolerance test (OSTT) in streptozotocin-induced diabetic rats. Male Wistar rats were fed a high-fat diet for 2 weeks and then a single dose of streptozotocin (35 mg/kg B.W) was administered by intraperitoneal injection. Rats with fasting blood glucose levels above 126 mg/dL were randomly divided into 5 groups (n = 8/group) for the following treatments by gavage for 4 weeks: vehicle (normal control and diabetic control), 200 mg/kg B.W of TW or RB or 100 mg/kg B.W of oxyresveratrol (OXY). Results: OXY and mulberroside A were identified as the major components of TW and OXY, mongolicin, and kuwanon H for RB. A significant inhibitory activity on ${\alpha}-glucosidase$ was found for TW, RB, and OXY (p = 0.0099). There was a dose-dependent inhibition of TW and RB on the intestinal sugar uptakes in Caco-2 cells, showing a greater impact on fructose compared to glucose. The OSTT showed that TW and RB significantly delayed time to maximal concentration (p = 0.0088) and decreased maximal concentration (p = 0.0043) compared to the control group. Conclusion: These results suggest that TW and RB may have a postprandial hypoglycemic effect, particularly in the case of high fructose or sucrose intake. OXY was suggested as a contributor to the hypoglycemic effect of TW and RB. Further studies are needed for the systemic effect of TW and RB in circulation.

• Korean Journal of Ichthyology
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• v.19 no.4
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• pp.365-370
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• 2007

Two species, Psettina tosana and Pseudorhombus oculocirris, were collected firstly off the Saryang Island, South Sea of Korea. P. tosana is clearly distinguished from its related species, P. gigantea and P. iijimae, in having 9~10 pectoral fin rays, fewer number of lateral line scales, colorless snout region, and no gill rakers on the upper limb of gill arch. P. oculocirris much differs from P. pentophthalmus in having flattish and free rays of anterior dorsal fin, lots of scales in the lateral line, and tubular anterior nostril with flap on ocular side only.

• Journal of the Korean Society for Precision Engineering
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• v.20 no.11
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• pp.171-179
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• 2003

This paper presents a rehabilitation exercise system which utilizes a 6 DOF robot as a motion generator. This system was proposed for a stroke patient or a patient who has hemiplegia. A master-slave system was designed to exercise either paralysis or abnormal limb by using normal limb motion. The study on the human body was applied to calculate the motion range of elbows and shoulders. In addition, a force-torque sensor was applied to the slave robot to estimate the rehabilitation extent of the patient. Therefore, the stability of the rehabilitation robot could be improved. By using the rehabilitation robot. the patients could exercise by themselves without assistance. In conclusion, the proposed system was verified by computer simulations and system experiment.