• Journal of Chest Surgery
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• v.43 no.5
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• pp.482-489
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• 2010

Background: The purpose of this study was to determine whether hand-measured carotid intima-media thickness (IMT) was a reliable and simple tool that could be used to evaluate the severity of stable coronary artery disease (CAD) with normal high-sensitivity C-reactive protein (CRP). Material and Method: We examined left carotid IMTs in 688 patients with stable CAD and excluded 121 patients with abnormally elevated hs-CRP ($\geq$0.5 mg/dL). We sought to determine the association between risk factors and the severity of stable CAD and carotid IMT in 567 patients who were divided into lower and higher groups based on the median value. Patients underwent a coronary artery angiogram and had at least significant stenosis (>50% of the original luminal diameter involving one or more major coronary artery). Result: Of the 567 patients, 300 (52.9%) were in the lower IMT group and 267 (47.1%) were in the higher IMT group; the median value was 0.76 mm. By multivariable logistic regression analysis, the following groups were different: older age (~49 vs. 70~ years, respectively; OR=6.552), high FBS (~99 vs. 120~ mg/dL; OR=1.713) and severity of CAD (1 vessel vs. 2 vessel disease; OR=1.711, 1 vessel vs. 3 vessel disease; OR=1.714). Conclusion: We conclude that there are correlations between increased carotid IMT and severity of CAD in stable angina patients with normal CRP levels.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.12
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• pp.1865-1870
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• 2014

To synthesize ${\omega}$-3 and ${\omega}$-6 balanced polyunsaturated fatty acid (PUFA) oil mixture, flaxseed oil and sesame oil were mixed and their anti-oxidative and sensory characteristics analyzed. For the fatty acid composition analysis results, the ${\omega}$-3 and ${\omega}$-6 PUFA ratios of the F20S80 oil mixture (flaxseed oil 20% and sesame oil 80% oil mixture) and F10S90 (flaxseed oil 10% and sesame oil 90% oil mixture) were represented as 1 to 10 and 1 to 5 ratio for ${\omega}$-3 and ${\omega}$-6 PUFA content from 4.4% to 42.1% and 8.9% to 39.7%, respectively. Since these were within 1:4~1:10 for healthy functional ${\omega}$-3 and ${\omega}$-6 balanced PUFA oil mixtures, these oil mixtures were healthy functional oil mixtures. To analyze anti-oxidative effects, acid values were analyzed. Samples were stored at room temperature, 70% relative humidity (RH) and $45^{\circ}C$, and 70% RH for 16 weeks. The acid value between F10S90 and S100 stored at $45^{\circ}C$ and 70% RH for 16 weeks were not statistically significant. The sensory characteristics such as oxidative odor and sesame odor and taste were not statistically significant among F20S80, F10S90, and sesame S100. Sensory characteristics between F10S90 and S100 stored at $45^{\circ}C$ and 70% RH for 16 weeks were not statistically significant. In conclusion, the sensory and oxidative characteristics of F10S90 were similar to those of S100. Therefore, F10S90 oil mixture should be used as a ${\omega}$-3 and ${\omega}$-6 balanced PUFA healthy functional oil mixture with high anti-oxidative effects.

• Journal of the Korean Chemical Society
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• v.53 no.5
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• pp.521-529
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• 2009

Molecular structures of the various conformers for the 1,3-dimethoxy-p-tert-butylthiacalix[4] crown-5-ether (3) were optimized by using DFT B3LYP/6 - 31 + G(d,p) and mPW1PW91/6 - 31 + G(d,p) (hybrid HF-DF) calculation methods. We have analyzed the energy differences and structures of eight in/out orientations (cone_oo, cone_oi, pc_oo, pc_io, pc_oi, pc_ii, 13a_oo, 13a_io) of two methoxy groups in three major conformations (cone, partial-cone and 1,3-alternate). The 13a_oo (out-out orientation of the 1,3-alternate conformer) is calculated to be the most stable among eight different conformations of 3, and in accord with the experimental result. The ordering of relative stability resulted from the mPW1PW91/6 - 31 + G(d,p) calculation method is following: 13a_oo > 13a_io$\sim$pc_io$\sim$cone_oo > cone_oi$\sim$pc_oo$\sim$pc_oi > pc_ii.

• Journal of the Microelectronics and Packaging Society
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• v.10 no.4
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• pp.21-27
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• 2003

The copolymers with various composition of methyl methacrylate (MMA), ethyl methacrylate (EMA), methacrylic acid (MA) and hydroxyethyl methacrylate (HEMA) were synthesized for capacitive humidity sensitive materials. The capacitive humidity sensor consisted of a polymethacrylate film coated on both sides with gold electrode. Capacitance versus relative humidity increased with HEMA content in the copolymer. In the case of self-crosslinkable MMA/MA/HEHA= 40/10/10, the average capacitance at 30%RH, 60%RH and 90%RH are 102, 134 and 166 pF, respectively. And also, the hysteresis, temperature cycle and long-term stability were evaluated as a capacitance humidity sensor.

• Journal of the Korean Chemical Society
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• v.45 no.1
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• pp.51-60
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• 2001

One-pot Mannich reaction of substituted hydroxy aromatic compounds with secondary amines in an aprotic solvent has been studied. The results demonstrate that the relative reactivity and regioselectivity of the Mannich reaction depend on the steric hindrance of amines as well as the nucleophilicity of hydroxy aromatic rings.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.1B
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• pp.1-7
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• 2012

Quasi-two dimensional numerical model (GSTARS) was applied to determine the optimal sediment discharge formula for simulating the sedimentologic characteristics of Hyeongsan river. The field measurements have been conducted to obtain the data, such as sediment discharge, bed material, and channel geometry, for model calibration and verification. The sediment discharge formulas, which have been generally used, have been assessed according to the average error, relative error, RMSE, RRMSE, discrepancy ratio and Nash-Sutcliffe efficiency coefficient for bed changes along the thalweg. From the results, Laursen formula(1958) shows the best performance to simulate the long-term bed change of Hyeongsan river.

• Korean Journal of Ichthyology
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• v.10 no.1
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• pp.61-66
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• 1998

The fish fauna and community structure were surveyed at the Naerin Stream of Puk'an River from June 1996 to September 1997. The fishes collected were 36 species, 28 genera belonging to 10 families, in which 16 species were endemic species of Korea. Oncorhynchus mykiss was an exotic fish. The dominant species was Zacco temmincki(relative abundance 42.94%), and subdominant species was Moroco kumgangensis(12.91%). The rare species less than 0.03% of all were Opsariichthys bidens, Squalidus japonicus coreanus, Misgurnus mizolepis, Leiocassis ussuriensis and Siniperca scherzeri. The species diversity, evenness, and dominance index on the fish community were 0.947, 0.609, and 0.218.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.388-392
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• 2015

본 연구에서는 고정하상 직하류부에서 발생하는 국부세굴현상을 분석하기 위해서 이동상 수리실험을 수행하였다. 순환식 유량공급이 가능한 개수로 실험장치에 아크릴로 제작된 사각형 모형을 설치하고 하류에 균일한 입경의 모래를 설치하여 다양한 수리조건과 시간변화에 따른 하상고의 변화를 측정하였다. 그리고 측정된 하상고 자료로부터 시간별 최대세굴심의 크기를 산정하여 분석하였다. 그 결과 세굴심의 상류부 경사는 일정한 값으로 유지되었고, 최대세굴심과 세굴공 길이, 최대세굴심 발생거리는 시간변화에 따라 증가폭이 점차적으로 감소하였다. 또한 세굴심의 시간변화식의 기울기와 경계지점에서의 수심평균 상대난류강도값과의 관계를 분석하였다. 세굴공 내에서는 하상근처에서 후류가 발생하고, 수심방향으로 유속편차가 극심하게 증가하는 분리전단층이 발생하였다. 본 연구에서 분석된 최대세굴심의 시간적 변화양상과 세굴심 내부에서 발생하는 흐름 및 난류강도 분포특성을 보다 면밀히 분석하여 세굴심의 발달에 영향을 미치는 인자를 이용하여 향후 적절한 세굴심의 예측식을 개발할 수 있고, 최대세굴심을 저감할 수 있는 방안을 제안할 수 있다.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.158-158
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• 2016

본 연구에서는 극치 분포의 오른쪽 꼬리 부분 예측 시 안정적인 확률수문량 산정하는 확률분포형과 매개변수 추정 방법을 평가하기 위해 Monte Carlo 모의를 수행하였다. 수문자료의 빈도해석에 적합한 것으로 알려진 generalized extreme value (GEV), Gumbel (GUM), generalized logistic (GLO), gamma3 (GAM3), normal (NOR), log-normal3 (LN3) 총 6개의 확률분포형을 바탕으로 오른쪽 꼬리 부분의 확률수문량 추정 성능을 모의 실험을 통해 평가하고자 한다. 30년 이상 자료를 보유한 기상청 지점의 지속기간별 연최대값 자료를 분석한 결과를 바탕으로 모분포를 GEV분포로 선정하였으며 평균이 1.0, 표준편차 0.5, 왜곡도 계수는 0.5, 1.0, 2.0, 3.0, 4.0이 되도록 가정하였다. 또한 자료 길이에 따른 성능 평가를 위해 표본 크기 20, 50, 100, 150, 200개에 대해 분석을 수행하였다. 위와 같은 가정으로 총 25종류(왜곡도계수 5개 ${\times}$ 표본 크기 5개)의 발생된 모분포에 6가지의 확률분포형과 3가지의 매개변수 추정방법(모멘트법, 최우도법, 확률가중모멘트법)을 조합한 18가지의 모델을 비교 분석해보았다. 평가방법으로는 평균 제곱근 오차(Root Mean Square Error, RMSE), 편의(bias), 평균 상대오차(Mean Relative Difference, MRD), 평균 절대 상대오차(Mean Absolute Relative Difference, MARD)를 사용하여 적용 모델의 성능을 비교 분석하였다.

• Journal of Life Science
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• v.26 no.5
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• pp.603-607
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• 2016

A crude extracellular lipase from solvent-tolerant bacterium Pseudomonas sp. BCNU 106 was highly stable in the broad pH range of 4-10 and at temperature of 37℃. Crude lipase of BCNU 106 exhibited enhanced stability in 25% organic solvents such as xylene (121.85%), hexane (120.35%), octane (120.41 %), toluene (118.14%), chloroform (103.66%) and dodecane (102.94%) and showed excellent stability comparable with the commercial immobilized enzyme. In addition, the stability of BCNU 106 lipase retained above 110% of its enzyme activity in the presence of Cu²⁺, Hg²⁺, Zn²⁺ and Mn²⁺, whereas Fe²⁺ strongly inhibited its stability. The detergents including tween 80, triton X-100 and SDS were positive signals for lipase stability. Because of its stability in multiple organic solvents, cations and surfactants, the Pseudomonas sp. BCNU 106 lipase could be considered as a potential biocatalyst in the industrial chemical processes without using immobilization.