• Journal of Genetic Medicine
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• v.5 no.2
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• pp.125-130
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• 2008

Propose: To analyze the indications and cytogenetic results of midtrimester amniocentesis. Material and Methods: This study reviewed 2,523 cases of midtrimester prenatal genetic amniocentesis performed at MizMedi Hospital between January 2000 and December 2007. Results: The most frequent indication for midtrimester amniocentesis was advanced maternal age (45.9%), followed by positive serum markers (29.9%). Chromosomal aberrations were diagnosed in 110 cases (4.4%), for which numerical aberration accounted for 38 cases (34.5%), structural aberration accounted for 65 cases (59.1%), and mosaicism accounted for 7 cases (6.4%). Among the autosomal aberrations, there were 20 cases of trisomy 21 and 8 cases of trisomy 18. With respect to structural aberrations, there were 14 cases of reciprocal translocation and 8 cases of robertsonian translocation. The frequencies of chromosomal aberrations according to the indication were highest in individuals with a family history of chromosome abnormality 14.0% (8/57) followed by previous congenital anomaly 5.9% (2/34). Conclusion: Midtrimester amniocentesis is an effective tool for prenatal diagnosis. Indications such as advanced maternal age, maternal serum markers, and ultrasound are important for predicting abnormal fetal karyotypes.

• Childhood Kidney Diseases
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• v.7 no.2
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• pp.189-196
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• 2003

Purpose : Ureteral duplication is a common urologic anomaly and early diagnosis may prevent irreversible renal damage. We thus aimed to evaluate the benefits of prenatal sonography in early detection. Methods : We retrospectively studied 55 children with duplicated systems who were admitted to Severance Hospital, Yonsei University, Seoul, Korea from January 1998 to July 2003. Results : The mean age at diagnosis was 2.3 years old. 89% of the children had complete duplicated ureter. 47% of the children visited the hospital with an initial complaint of abnormal prenatal sonographic findings. Among these patients, 70.8% had DMSA defects. The mean differential renal function(DRF) in the DMSA scan was 48.2% in the group diagnosed prenatally. In the postnatally-diagnosed group, DMSA defects were found in 67.7% patients and the mean DRF was 45.5%. Conclusion : In comparison with the past studies, the mean age at diagnosis is becoming younger, and the proportion of abnormal prenatal sonography as an initial complaint larger. Other clinical manifestations were similar. The difference of the renal damage between the prenatally diagnosed group and the postnatally diagnosed group was not statistically significant. A multi-center study may help to prove the importance of prenatal sonography in early diagnosis and treatment of ureteral duplication. (J Korean Soc Pediatr Nephrol 2003;7:189-196)

• The Journal of Korean Academic Society of Nursing Education
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• v.19 no.4
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• pp.675-683
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• 2013

Purpose: Nineteen articles were analyzed to gather opinions and nursing implications about NIPT recently launched. Methods: Nineteen articles were selected from EBSCO (eBook business collection), Google Scholar, and two Korean academic d-bases with key words 'prenatal screening testing', 'prenatal genetic diagnostic testing', NIPT or 'cell free DNA (cfDNA)'. Authors developed a framework for analyzing the 19 articles including opinions and suggestions for future implications. Results: Eleven articles written by the first author affiliated with medicine or genetics, viewed NIPT as promising because of safety, accuracy, early detectability and cost effectiveness. Articles written by journalists or authors affiliated with history and ethics were concerned with the possible risk of ELSI (ethical, legal, social issues), erratic interpretation of test results, and lack of genetic counseling service. Conclusion: With consideration of Korean clinical, and legal circumstances, not only pregnant women and families but also health professionals must prepare for clinical NIPT implications including updating prenatal genetic testing, counseling services, protecting ELSI and amulticultural team approach.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.8
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• pp.3897-3906
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• 2013

The purpose of this study was to identify the rate and influencing factors on antepartum depression in pregnant women. A self-administered questionnaire-based study was performed in 160 pregnant women who visited outpatient clinics or attended special lectures of the general hospital in D metropolitan city. All participants were interviewed using the Korean version of Edinburgh Postnatal Depression Scale(EPDS). The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and stepwise multiple regression. On the results, the mean score of antepartum depression was $7.80{\pm}4.86$ scores(0-30 scores). The percentage of all participants for EPDS scale were 56.3% with normal level, 20.6% with a boundary line and 23.1% with serious level. Influencing factors on antepartum depression were accounted for 36.7% of the total variance which consisted of perceived health status, pregnancy stress and self esteem. The results indicate that these variables should be considered in preventing depression of pregnant women.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.1177-1179
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• 2012

최근 전력 수요가 지속적으로 증가함에 따라서, 전력 수급을 관리하는 EMS 에 대한 관심이 높아지고 있다. 전력 수급을 안정적으로 관리하기 위해서는 전력 계통의 상태변화에 따라 급전원에게 실시간 알람을 발생시켜주는 알람 시스템이 반드시 필요하다. 그러나 기존 EMS 의 알람 시스템은 알람 인지자의 역할을 고려하지 않고 알람 발생 여부를 알려주고 인지함으로써 보안상의 문제점을 가지고 있다. 본 논문에서는 RBAC 기반의 EMS 알람 시스템을 제안한다. 제안된 시스템을 통해 EMS 의 알람 시스템은 허가된 급전원에게만 알람 발생 여부를 알려주고 알람을 수신한 급전원이 직접 알람을 인지하도록 한다. 또한, 수신한 급전원이 원거리에 위치할 경우, 근거리 급전원에게 알람의 인지를 위임함으로써 알람 시스템의 보안을 강화한다.

• Childhood Kidney Diseases
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• v.6 no.2
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• pp.178-187
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• 2002

Purpose : The detection of hydronephrosis(HN) with antenatal ultrasonography was first reported in the 1970s. Prenatal HN is diagnosed with an incidence of 1:100 to 1:500 on antenatal screening. Recently, the purpose of antenatal screening has changed from simple detection to selection for specific diagnosis-based management. this study is to evaluate the usefulness of antenatal sonography for HN and to investigate the differential causes of HN and their clinical outcomes. Patients and methods : 11,783 live neonates with prenatal ultrasonographic examination at Ajou University School of Medicine, from Sep. 1994 to Aug. 2001 were analyzed. Results and conclusion : Hydronephrosis (>10 mm) was detected in 119 (1.0%) cases antenatally and among these, 91 were proved to have HN postnatally Males were three times more affected than females. Additional imaging studies revealed that ureteropelvic junction obstruction was the most common postnatal diagnosis (47%), followed by multicystic dysplastic kidney, vesicoureteral junction obstruction and vesicoureteral reflux. During 20 months' follow-up(3 to 72 months), 58(48%) renal units showed spontaneous resolution and surgical interventions were necessary in 10 (7.4%) of postnatally confirmed hydronephrotic renal units.

• 가정의 벗
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• v.34 no.11 s.399
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• pp.26-26
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• 2001

• KOREAN POULTRY JOURNAL
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• s.18
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• pp.112-114
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• 1971

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.271-284
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• 2016

This study was carried out to evaluate the efficacy of CBT for perinatal depression through systematic literature review and meta-analysis. The following databases were used to search the literature: CINAHL, PubMed, EMBASE, Koreamed, Library of Korean Congress, KISS, and Korean Academic Publication Database. Keywords included 'perinatal depression,' 'pregnant women,' and 'cognitive behavioral therapy,' and the evaluated articles were published up to May 2016. Using the R program, the effect size of perinatal depression and anxiety were calculated by random-effects model. The heterogeneity of the effect size was analyzed by data moderator analysis using the meta-ANOVA. Furthermore, the funnel plot, Egger's regression test, fail-safe N, trim-and-fill test, and publication bias analysis were conducted and used to verify the results. Out of the 180 selected articles, 16 clinical trial studies were meta-analyzed. Each articles were evaluated for the risk of bias by the checklist of SIGN; the overall risk of bias was low. The effect size of CBT for perinatal depression was Hedges' g=-0.55 (95% CI: -0.76~-0.33), which was a moderate level, while for anxiety reduction, Hedges' g=-0.20 (95% CI: -0.48~-0.08) and it was not statistically significant. Heterogeneity or risk of publication bias were low. This meta-analytic study found that CBT is moderately effective in reducing perinatal depression in pregnant women.

• RED RIBBON
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• s.63
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• pp.24-25
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• 2005

2005년 1월 30일 뉴욕타임즈는 미국에서의 에이즈 수직감염률이 거의 소멸되어 간다고 보고 했다. 1990년대에는 일년에 약 2,000건이 발생하던 것이 2003년도에는 약 200건이 발생하였으며 그 발생률은 더욱 낮아지리라고 예상하고 있다. 이렇게 수직감염률이 낮아진 이유는 대중의 에이즈에 대한 인식(awareness)이 향상되면서 자발적으로 에이즈 검사를 받고, 산전 진찰을 철저히 받고 있기 때문이라고 설명하고 있다. 최근 미국의 에이즈 역학에서 중요한 점은 가임기에 있는 여성, 특히 흑인여성들 사이에서의 에이즈 발생률이 가장 높다는 점인데, 이는 이들이 산전진찰을 통하여 에이즈 검사를 통한 진단을 받는 비율이 높고, 이러한 이유로 인하여 수직감염률은 반대로 낮아지는 양상을 보이는 것이 아닌가 유추할 수 있다.