• Title/Summary/Keyword: 비약물 치료

Search Result 543, Processing Time 0.031 seconds

Management of Weight Gain and Obesity Associated With Antipsychotics (항정신병약물 사용과 연관된 체중 증가와 비만의 관리)

  • Lee, Na-Hyun;Lee, Jae-Chang
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.29 no.2
    • /
    • pp.86-94
    • /
    • 2021
  • Objectives : The risk of weight gain is high when using antipsychotic drugs, and the prevalence of obesity in people with mental illness is high. Obesity management in psychiatric patients is important because obesity causes various complications and lowers treatment adherence and quality of life. Methods : In this review, we summarized the management strategies for obesity that can occur when using antipsychotic drugs through a web search. Results : Evaluate obesity-related risk factors and related indicators from the beginning of treatment, and conduct regular monitoring. If an antipsychotic drug is used and obesity is induced, a change to a drug with a low metabolic risk may be attempted. Sufficient interventions are also needed on the need to manage obesity, a healthy diet, and exercises in patients and their families. If weight loss is not achieved and obesity-related complications are associated, the use of anti-obesity drugs may be considered. Pharmacological treatment approaches should be carefully considered. Conclusions : Non-pharmacological and pharmacological therapies can be applied to manage weight gain and obesity caused by the use of antipsychotic drugs. When using anti-obesity drugs, the characteristics of mental disorders, drug safety, and drug interactions should be considered.

The Effect of Nonpharmacologic Interventions on Behavioral and Psychological Symptoms of Dementia : A Meta-Analysis (치매환자의 행동심리증상에 비약물적 중재가 미치는 효과 - 메타분석)

  • Kwon, Mi-Hwa;Lee, Jae-Shin
    • The Journal of the Korea Contents Association
    • /
    • v.17 no.6
    • /
    • pp.540-550
    • /
    • 2017
  • To investigate a variety of nonpharmacologic interventions have confirmed what the symptoms and effects, mainly interventions by acting on behavioral and psychological symptoms of dementia was conducted a meta-analysis. Data were collected from online search engines using search words from domestic and foreign article database. The researcher independently and among the pre-post experimental studies published from January 2000 to June 2016, recalled applying for the elderly with dementia presents the effect of treatment group and the control group RCT in this study were included in the study. The results of this meta-analysis showed that, effect size of the nonpharmacologic interventions of total -0.33, occupational therapy - 0.26, multi-sensory stimulation intervention -0.65 was significant beneficial effects to elderly with dementia(p<.05). According to interventions as a major affected the symptoms associated with behavioral problems, mainly aggression, memory-related problem behavior in the home-based program. Also, reminiscence therapy and occupational therapy is generally apathy, multi-sensory stimulation and music therapy was confirmed that there was a major change in behavior anxiety or agitation. The results of this study confirmed that various nonpharmacologic interventions were effective on behavioral psychological symptoms of dementia patients and confirmed the main symptoms of intervention.

비만치료제 개발의 접근 방법

  • 박명환
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 2001.04a
    • /
    • pp.33-42
    • /
    • 2001
  • 최근 수년간 에너지 섭취와 소비의 균형을 유지하는 것과 깨지는 것에 대한 생리적 기전에 대하여 많은 것이 알려졌다. 비만 만연의 사회적 문제점, 치료해야할 필요성, 음식섭취와 에너지 항상성의 조절 기전, 이와 관련된 물질과 수용체의 기능과 가치, 잠재력 있는 조절인자의 대상에 대하여 기술하였다. 비만은 여러 생리과정의 총화이므로 신체의 즉각적, 장기적 에너지 수요를 원활하게 조절하는 다양한 분자신호전달체계에 각각 작용하는 물질을 찾아 함께 사용하도록 하는 것이 새로운 비만치료제를 개발하는 전략이다.

  • PDF

Non-Pharmacological Interventions for Behavioral and Psychological Symptoms of Neurocognitive Disorder (신경인지장애의 정신행동증상에 대한 비약물학적 개입)

  • Hyun Kim;Kang Joon Lee
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.31 no.1
    • /
    • pp.1-9
    • /
    • 2023
  • Patients with neurocognitive disorder show behavioral psychological symptoms such as agitation, aggression, depression, and wandering, as well as cognitive decline, which puts a considerable burden on patients and their families. For the treatment of behavioral psychological symptoms, patient-centered, non-pharmacological treatment should be used as a first line approach. This paper describes non-pharmacological interventions to manage and treat behavioral psychological symptoms in patients with neurocognitive disorder. In order to control behavioral psychological symptoms such as agitation, depression, apathy, insomnia, and wandering, it is important to identify and evaluate factors such as environmental changes and drugs, and then solve such problems. Non-pharmacological interventions include reassurance, encourage, distraction, and environmental change. It is necessary to understand behavior from a patient's point of view and to approach the patient's needs and abilities appropriately. Reminiscence therapy, music therapy, aroma therapy, multisensory stimulation therapy, exercise therapy, light therapy, massage therapy, cognitive intervention therapy, and pet therapy are used as non-pharmacological interventions, and these approaches are known to improve symptoms such as depression, apathy, agitation, aggression, anxiety, wandering, and insomnia. However, the quality of the evidence base for non-pharmacological approaches is generally lower than for pharmacological treatments. Therefore, more extensive and accurate effectiveness verification studies are needed in the future.

Current Knowledge on Fatigue in Advanced Cancer Patients (진행된 암환자에서 피로의 최신지견)

  • Kim, Jung-Hyun;Choi, Youn-Seon
    • Journal of Hospice and Palliative Care
    • /
    • v.11 no.4
    • /
    • pp.175-180
    • /
    • 2008
  • 진행된 암환자에서 피로는 70% 이상이 경험하게 되는 흔한 증상이며 삶의 질을 저하시키는 주된 요인이다. 피로에 대한 선별검사는 "피곤하거나 지친감이 있나요?"라는 단순한 질문으로 가능하며 이미 개발된 평가도구를 사용하여 평가할 수 있다. 동반 질환이나 피로의 원인을 알기 위한 병력청취와 검사실 검사가 필요할 수 있으며 결과에 따라 가역적 인자를 치료하는 과정이 우선되어야 한다. 적절한 약물치료를 시행하여 증상을 호전시킬 수 있으며 이중 methylphenidate는 암 연관 피로를 호전시키고 마약성 진통제에 의한 진정에 효과가 입증되었다. 환자의 여명에 따라 부신 피질 호르몬제도 사용할 수 있고, 운동 및 환자의 교육과 영양관리 또한 중요하다.

  • PDF

NEW DRUG THERAPY IN CHILD AND ADOLESCENT PSYCHIATRY ATYPICAL ANTIPSYCHOTICS (소아청소년 정신과 영역에서의 새로운 약물치료 ; 비정형 항정신병약물)

  • Bahn, Geon-Ho
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • v.14 no.1
    • /
    • pp.26-35
    • /
    • 2003
  • Conventional antipsychotics are commonly used to treat children and adolescents suffered from schizophrenia to other neuropsychiatric conditions. Regrettably, studies for typical antipsychotics report high rates of sedation, orthostatic hypotension, and extrapyramidal side effects. Over the past few years, atypical antipsychotics have been prescribed for use in adults with psychotic symptoms. Child psychiatrists have begun using these drugs to children and adolescents hoping safe and better alternatives to the conventional antipsychotics. However, there is not enough short-term and almost no long-term data about atypical antipsychotics for pediatric patients. Therefore, the purpose of this article is to review what is known about the use of the atypical antipsychotics in young patients. To do so, an appropriate approach to the use of these drugs in child and adolescent patients my be offered.

  • PDF

의학 - HIV 치료의 최신지견

  • Bang, Ji-Hwan
    • RED RIBBON
    • /
    • s.82
    • /
    • pp.20-21
    • /
    • 2009
  • 강력한 항레트로바이러스 치로(highly active antiretroviral therapy, HAART)의 도입으로 HIV 감영인의 기대여명(life expectancy)이 비감염인과 큰 차이가 나지 않을 정도로 향상된 것은 널리 알려진 사실이다. 하지만 평생 동안 약물을 복용해야 하며, 이에 따른 약물 부작용, 약제 내성, 경제적 손실, 불편함 등이 문제가 되고 있으며, 이를 극복하기 위한 다양한 치료법에 대한 연구가 진행 중이다. 이 글에서는 최근 발표되거나 진행 중인 새로운 치료 방법에 대해 간단히 알아보고자 한다.

  • PDF

Biofeedback Treatment for Insomnia (불면증의 바이오피드백 치료)

  • Koo, Moon-Sun;Yu, Bum-Hee
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.14 no.1
    • /
    • pp.18-24
    • /
    • 2006
  • Insomnia is associated with numerous psychiatric and physical conditions, and hyperarousal is known to play an important role in the development of insomnia. There are a lot of limitations to use hypnotic medications for the treatment of insomnia. As psychological factors can greatly affect the development and progress of insomnia, several non-pharmacological treatment methods have been used for insomnia. Biofeedback is effective in the treatment of insomnia and its treatment effect lasts considerably long. Biofeedback together with relaxation techniques can reduce levels of arousal in insomnia patients so that they are effective for induction and maintenance of sleep. In conclusion, biofeedback treatment seems to be very helpful for insomnia patients who show high levels of arousal and have limitations in the use of hypnotic medications.

  • PDF

Delirium Management: Diagnosis, Assessment, and Treatment in Palliative Care (섬망의 돌봄: 완화의료 영역에서의 진단, 평가 및 치료)

  • Seo, Min Seok;Lee, Yong Joo
    • Journal of Hospice and Palliative Care
    • /
    • v.19 no.3
    • /
    • pp.201-210
    • /
    • 2016
  • Delirium is a common symptom in patients with terminal cancer. The prevalence increases in the dying phase. Delirium causes negative effects on quality of life for both patients and their families, and is associated with higher mortality. However, some studies reported that it tends to remain unrecognized in palliative care setting. That may be related with difficulties to distinguish the symptom from others with overlapping characteristics such as depression and dementia, and a lack of knowledge regarding assessment and diagnostic tools. We suggest that accurate recognition with validated tools and early diagnosis of the symptom should be highly prioritized in delirium management in palliative care setting. After diagnosing delirium, it is important to identify and address reversible precipitants such as medication, dehydration, and infection. Non-pharmacological interventions including comfortable environment for the patient and family education are also essential in the management strategy. If such interventions prove ineffective or insufficient to control hyperactive symptoms, pharmacologic interventions with antipsychotics and benzodiazepine can be considered. Until now, low levels of haloperidol remains the standard treatment despite a lack of evidence. Atypical antipsychotics such as olanzapine, quetiapine and risperidone reportedly have similar efficacy with a stronger sedating property and less adverse effect compared to haloperidol. Currently, delirium medications that can be used in palliative care setting require more clinical trials, and thus, clinical guidelines are not sufficiently available. We suggest that it is warranted to develop clinical guidelines based on well-designed clinical studies for palliative care patients.