• Proceedings of the SCSK Conference
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• 1996.07a
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• pp.33-51
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• 1996

화장품의 변질요인은 크게 물리적 또는 화학적 변화에 의한 요인과 미생물오염으로 인한 각종 문제점으로 대별될 수 있다. 이 중에서 미생물 오염문제는 제품의 상품가치에 미치는 영향 뿐만 아니라 지속적인 사용에 의한 피부의 위생적 측면때문에 그 중요성에 대한 인식이 높아지고 있다. 따라서, 제품개발시는 화장품 처방중의 영양성분의 배합, pH, 유화형태, 방부제의 혼합, 분배계수 및 그 안정성을 고려하여야 함은 물론이고 처방중의 모든 원료의 각각에 대한 항균능 및 피부자극여부를 사전에 미리 조사하여 각 제품별로 적당한 방부체계를 선택하는 것은 매우 중요한일이다. 독성실험방법에 있어서 in vivo 실험에 대체할 수 있는 새로운 in vitro 실험방법 수립 즉, 동물실험을 하지 않고 in vitro 실험결과로부터 in vivo 결과를 예측할 수 있도록 새로운 in vitro 실험체계의 가능성을 실험하였다. 4종의 cell line중 transformed mouse fibroblast L929가 본 실험에서 사용하기에 배양상의 용이성과 안정성, 재현성의 관점에서 가장 알맞은 cell line이었다. transformed mouse fibroblast L929를 사용한 NR$_{50}$ assay와 Draize score간의 regression coefficient ${\gamma}$값은 0.91이었다. 혈청은 시험물질의 세포에 대한 민감성에 영향을 주었다. 따라서, modified serum-free method를 이용함으로써 regression coefficient가 증가된 즉, 상관성 및 재현성이 높은 결과를 얻을 수 있었다. 이러한 기술은 독성실험에 실험동물을 사용하지 않고 in vivo test에 대체 할 수 있고, 또한 화학물질에 대한 prescreening으로 이용할 수 있을 것으로 판단된다.원과 섭식장소, 수중생물의 경우는 특히 수온, 수량 영양원등이다.(중략). 본 연구의 접근방법으로는 ASRS의 개념적인 Reference Model을 수립하고 이 Reference Model에 대한 Formal Model로 DEVS(Discrete Event System Specification)을 이용하여 시스템을 Modeling하였다. 이의 Computer Simulation을 위하여 DEVS형식론 환경에서의 Simulation Language인 DEVSim ++ⓒ를 이용하여 시스템을 구현하였다.. 실형 결과로는 먼저 선형 상미분방정식의 예로 mass-damper-spring system, 비선형 상미분방정식의 예로는 van der Pol 방정식, 연립 상미분방정식의 예로는 mixing tank problem 등을 보였으며, 그의 공학에서 일어나는 여러 가지 문제들도 다루었다.화물에 대한 방어력이 증가되어 나타난 결과로 여겨지며, 또한 혈청중의 ALT, ALP 및 LDH활성을 유의성있게 감소시키므로서 감잎 phenolic compounds가 에탄올에 의한 간세포 손상에 대한 해독 및 보호작용이 있는 것으로 사료된다.반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경우는 홍삼으로 가공되면서 발생하는 경우가 있고, 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$ elements)로 가정한다. 즉, [+wh] 의미의 겹의문사는 동일한 구성요 소를 지닌 병렬적 합성어([$[W1]_{XO-}$ $[W1]_{XO}$ ]

• Journal of the Korean GEO-environmental Society
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• v.20 no.2
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• pp.69-79
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• 2019

The coastal area forms various sedimentary layers according to the environmental conditions such as the topography and geological features of the upper region of the river, ocean currents, and river mouth. Therefore, identifying the characteristics of the marine clay deposited in the coastal area plays a key role in the investigation of the formation of soft ground. In general, alluvial grounds are formed by a variety of factors such as changes in topography and natural environment, they have very diverse qualities depending on the deposited region or sedimentation conditions. The most important thing for the construction of social infrastructures in soft ground areas is economical and efficient treatment of soft ground. In this study, the author collected data from diverse laboratory and field tests on five areas in western and southern offshore with relatively high reliability, and then statistically analyzed them, thereby presenting standard constants for construction design. Correlation between design parameters such as over consolidation ratio, preconsolidation pressure was analyzed using linear and non-linear regression analyses. Also, proposed distribution characteristics of design parameters in consideration of each region's uncertainty through statistical analyses such as normality verification, outlier removal.

• Journal of the Korean Geotechnical Society
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• v.35 no.4
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• pp.15-26
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• 2019

The stability of the gravity quay wall against earthquakes is evaluated on the basis of the allowable displacement of the wall. To estimate the displacement caused by external forces, empirical equations based on the Newmark sliding block method or numerical analysis are widely used. In numerical analysis, it is possible to analyze precisely a complicated site and structure, but difficult to set the appropriate parameters and environments; there are limitations in obtaining reliable results, depending on one's level of expertise. The Newmark method, with only seismic motions, is widely used because it is simpler than numerical simulations when estimating permanent displacement. However, the empirical equations do not have any parameters for the response characteristics and sliding block of the structure, and sliding blocks being assumed as rigid bodies does not consider the nonlinear behavior of the soil and interaction with the structure. Therefore, in order to evaluate the seismic stability of the gravity quay wall, a newly-developed empirical equation is needed to overcome the above-mentioned limitations. In this study, numerical simulations are performed to analyze the response characteristics of the backfill of the structure, and to propose an optimal method of calculating the active area. For this purpose, finite element analyses were performed to analyze the response characteristics, and stress-strain relationships for various seismic motions. As a result, the response characteristics, sliding block, and failure surface of the backfill vary depending on the input seismic motions.

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.142-152
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• 2019

This study aimed to explore the association between obesity index and heart rate variability (HRV) in college-aged male smokers. A total of 85 male college students (> 10 cigarettes per day for at least 3 years) were participated in this study. According to a standardized protocol, body mass index (BMI), percent body fat (%BF), waist circumference (WC), and waist-to-hip ratio (WHR) were taken as obesity indices. Resting r-r interval was monitored for HRV analysis as an indicator of cardiac autonomic regulation. Compared with low WHR subjects, high WHR subjects had significantly lower values of rMSSD, pNN50, HF, and SD1, suggesting decreased parasympathetic activity. No such differences in LF/HF ratio were found between the WHR-based subgroups. Bivariate correlation analysis showed that obesity indices of WC, WHR, and %BF were significantly associated with rMSSD, pNN50, HF, and SD1, with a tendency for correlation coefficient to be higher with WHR than with WC or %BF. No significant association was found between BMI and HRV parameters indicative of parasympathetic activity. This study suggest that central obesity is significantly associated with decrease in parasympathetic activation, independent of BMI as an indicator of obesity, in male college smokers.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.2
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• pp.93-101
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• 2019

The objective of this study is to develop a model which can predict the seismic performance of the slope relatively accurately and efficiently by using artificial neural network(ANN) technique. The quantification of such the seismic performance of the slope is not easy task due to the randomness and the uncertainty of the earthquake input and slope model. Under these circumstances, probabilistic seismic fragility analyses of slope have been carried out by several researchers, and a closed-form equation for slope seismic performance was proposed through a multiple linear regression analysis. However, a traditional statistical linear regression analysis has shown a limit that cannot accurately represent the nonlinearistic relationship between the slope of various conditions and seismic performance. In order to overcome these problems, in this study, we attempted to apply the ANN to generate prediction models of the seismic performance of the slope. The validity of the derived model was verified by comparing this with the conventional multi-linear and multi-nonlinear regression models. As a result, the models obtained through the ANN basically showed excellent performance in predicting the seismic performance of the slope, compared to the models obtained by the statistical regression analyses of the previous study.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.30 no.6
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• pp.270-285
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• 2018

The behavior of wave-induced pore water pressure inside the rubble mound and seabed, and the resultant structure failure are investigated, which are used in design of the composite breakwater representing the coastal and harbor structures. Numerical simulation techniques have been widely used to assess these behaviors through linear and nonlinear methods in many researches. While the combination of strongly nonlinear analytical method and turbulence model have not been applied yet, which can simulate these characteristics more accurately. In this study, olaFlow model considering the wave-breaking and turbulent phenomena is applied through VOF and LES methods, which gives more exact solution by using the multiphase flow analytical method. The verification of olaFlow model is demonstrated by comparing the experimental and numerical results for the interactions of regular waves-seabed and regular waves-composite breakwater-seabed. The characteristics of the spatial distributions of horizontal wave pressure, excess-pore-water pressure, mean flow velocity and mean vorticity on the upright caisson, and inside the rubble mound and seabed are discussed, as well as the relation between the mean distribution of vorticity size and mean turbulent kinetic energy. And the stability of composite breakwater are also discussed.

• MARITIME LAW REVIEW
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• v.29 no.2
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• pp.115-144
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• 2017

The impact of the global financial crisis, which began in the United States in 2007, had a major impact on the domestic shipping and shipbuilding industries. In this regard, the domestic shipyard has established an order-taking strategy in several ways as an alternative to lowering the amount of construction of commercial vessels due to deterioration of the shipping industry, and selected industrial sector was the offshore plant sector. However, the domestic shipyard has under performed the offshore plant in order to just increase sales and secure work without any risk analysis for EPC contracts. As a result, the shipyard has been charged more than the initial contract price with the offshore plant contractor, or the shipyard has become a legal issue requiring payment of liquidated damages due to delays in delivery of the product. The main legal disputes are caused by the thorough risk analysis and the inexperience of process control that can occur during offshore plant construction. and In particular, there is no sufficient review of the unequivocal provisions in the contract as an element of risk management. There is no human resource to review these contractual clauses. Therefore, this study identifies the existence of specific risks that could lead to delays in offshore plant construction, and examined the existence of any unequivocal clauses in contracts for offshore plant construction. and also discussed how the toxic clause applies to the actual parties and how the concrete risk factors in the construction contracts are transferred and expressed by referring to the interviews with the project manager of the domestic shipyard and the previous research. As a result, This paper examined the legal liability of the contracting parties regarding delayed delivery of the products due to the offshore plant construction contract. And to improve the domestic shipbuilding industry.

• Journal of the Korean Geotechnical Society
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• v.36 no.12
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• pp.77-86
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• 2020

In this study, the importance of implied strength correction for shallow depths at a region of moderate to low seismicity with primary focus on its effect upon site natural period and mean period of the ground motion is investigated. In addition to the most commonly used Modified Kondner-Zelasko (MKZ) model, this paper uses a quadratic/hyperbolic (GQ/H) model that can capture the stress - strain response at large strains as well as small strain stiffness dependence. A total of six site profiles by downhole tests are used and 1D site response analyses are performed using three input motions with contrasting mean periods. The difference between non-corrected and corrected analyses is conditional on the site period as well as mean ground motion period. The effect of periods is analyzed by correlating them with the effective peak ground acceleration, maximum shear strains and amplification factors. The comparative study reveals that the difference is more prominent in soft sites with long site periods. Insignificant differences are observed when soil profiles are subjected to ground motion with very short mean period.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.5
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• pp.9-16
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• 2020

A CFRP sheet has been applied as a structural reinforcement in the field, and various studies are conducted to evaluate the effect of CFRP sheets on reinforced concrete. Although many experiments were performed from previous studies, there are still limitations to analyze structural behaviors with various parameters in experiments directly. This study shows the FEA on structural behaviors of RC beams reinforced with CFRP sheets using ABAQUS software. To simulate debonding failure of CFRP sheets which is a major failure mode of RC beam with CFRP sheets, a cohesive element was applied between the bottom surface of RC beam and CFRP sheets. Both quasi-static method and 2-D symmetric FE model technique were performed to solve nonlinear problems. Results obtained from the FE models show good agreements with experimental results. It was found that reinforcement level of CFRP sheets is closely related to structural behavior of reinforced concrete including maximum strength, initial stiffness and deflection at failure. Also, as over-reinforcement of CFRP sheets could give rise to the brittle failure of RCstructure using CFRP sheets, an appropriate measure should be required when installing CFRP sheets in the structure.

• Journal of Internet Computing and Services
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• v.23 no.4
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• pp.21-33
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• 2022

Recently, the recommender system has been widely used in various fields such as movies, music, online shopping, and social media, and in the meantime, the recommender model has been developed from correlation analysis through the Apriori model, which can be said to be the first-generation model in the recommender system field. In 2005, many models have been proposed, including deep learning-based models, which are receiving a lot of attention within the recommender model. The recommender model can be classified into a collaborative filtering method, a content-based method, and a hybrid method that uses these two methods integrally. However, these basic methods are gradually losing their status as methodologies in the field as they fail to adapt to internal and external changing factors such as the rapidly changing user-item interaction and the development of big data. On the other hand, the importance of deep learning methodologies in recommender systems is increasing because of its advantages such as nonlinear transformation, representation learning, sequence modeling, and flexibility. In this paper, among deep learning methodologies, RNN, CNN, and GAN-based models suitable for sequential modeling that can accurately and flexibly analyze user-item interactions are classified, compared, and analyzed.