• Journal of Embryo Transfer
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• v.21 no.1
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• pp.53-58
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• 2006

This study was conducted to comparing on vitrification of mouse oocytes and embryos using CPS, conventional straws and CPS by evaluating in morphological survival for oocytes, and embryonic cleavages and blastocyst formation for embryos. The morphological survival in vitro after thawing of vitrified oocytes using CPS (75%) and conventional straws (72%) were significantly higher (p<0.05) than that using OPS (68%). The blastocyst formation rates of vitrified embryos using CPS (48.6%) and unfrozen control embryos (56.0%) were significantly higher (p<0.05) than those of conventional straws (43.4%) and OPS (37.7%). The rates of morula formation were also higher to control, CPS, conventional straws and OPS in orderly. These results show that CPS has the advantages of achieving a high survival and safety preservation.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.3
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• pp.223-230
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• 2001

Since self-organizing map (SOM) preserves the topology of ordering in input spaces and trains itself by unsupervised algorithm, it is Llsed in many areas. However, SOM has a shortcoming: structure cannot be easily detcrmined without many trials-and-errors. Structure-adaptive self-orgnizing map (SASOM) which can adapt its structure as well as its weights overcome the shortcoming of self-organizing map: SASOM makes use of structure adaptation capability to place the nodes of prototype vectors into the pattern space accurately so as to make the decision boundmies as close to the class boundaries as possible. In this scheme, the initialization of weights of newly adapted nodes is important. This paper proposes a method which optimizes SASOM with genetic algorithm (GA) to determines the weight vector of newly split node. The leanling algorithm is a hybrid of unsupervised learning method and supervised learning method using LVQ algorithm. This proposed method not only shows higher performance than SASOM in terms of recognition rate and variation, but also preserves the topological order of input patterns well. Experiments with 2D pattern space data and handwritten digit database show that the proposed method is promising.

• Restorative Dentistry and Endodontics
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• v.36 no.1
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• pp.12-18
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• 2011

Objectives: This retrospective study evaluated the therapeutic effects of the intentional replantation (IR) procedure performed on the maxillary and mandibular molars of 35 patients. Materials and Methods: For the subjects, IR was performed due to difficulties in anatomically accessing the lesions and/or close proximity to the thick cortical bone, inferior alveolar nerve, or maxillary sinus, which rendered the ordinary periradicular surgery impossible. The patients'progress was followed for a year and up to 2 years and 4 months. The success of the procedure was evaluated in terms of clinical and radiographic success (%). Results: The results revealed the following: (a) 1 case (3%) of failed tooth extraction during IR; (b) 2 cases (6%) of extraction due to periodontal diseases and inflammatory root resorption; (c) 3 cases (9%) of normally functioning teeth in the oral cavity with minor mobility and apical root resorption, and; (d) 29 cases (82%) of normally functioning teeth without obvious problems. Conclusions: IR was confirmed to be a reliably repeatable, predictable treatment option for those who cannot receive conventional periradicular surgery because of anatomic limitations or patient factors.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.478-478
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• 2021

전 세계적으로 많은 나라들이 기후변화에 적응하기 위해 수자원 관리 전략을 마련하고 있으며, 수자원의 근간이 되는 빗물의 효율적 사용을 위해 우리나라에서도 빗물이용시설이 많이 도입되고 있다. 본 연구에서는 사용자 편의 환경(graphical user interface; GUI)을 갖춘 빗물이용시설의 용량 결정 프로그램(capacity design aid for rainwater harvesting; CARAH)을 개발하여 관련 연구와 업무에 활용성을 높이고자 하였다. CARAH는 저수지 질량 보존식과 python의 pyswarm package에 탑재된 메타 휴리스틱 방법 중 하나인 입자 군집 최적화(particle swarm optimization; PSO) 기법을 연계하여 빗물이용시설의 최적 용량을 짧은 시간에 결정될 수 있도록 개발되었다. 그리고, C#의 Windows Forms Application을 이용하여 사용자 편의 환경을 구현하였다. CARAH의 입력 자료는 모의 기간, 유입량, 목표공급량, 공급보장률이고, 출력 자료는 공급보장률-저류조용량, 목표공급량-실공급량-미달성량, 저류용량-유입량-실공급량이다. 빗물이용시설 계획에 필요한 여러 입력 자료를 쉽게 입력할 수 있도록 구현하였고, 그래프와 표의 형태로 계산된 결과를 화면에 직접 표출함으로써 사용자가 직관적으로 확인할 수 있도록 하였다. 한편, 입·출력 자료를 포함한 분석 결과는 파일로 관리할 수 있도록 기능을 갖추어 수정 및 보완 등의 반복적 활용이 가능하도록 하였다. 개발된 프로그램의 활용성을 검토하기 위해 실제 저류지가 설계된 인천의 청라지구 1공구를 대상으로 적용하였고, 분석 결과의 적절성을 확인하였다. 본 연구에서 개발된 CARAH는 빗물이용시설의 용량 결정에 관한 효율을 높일 수 있는 프로그램이고, 누구나 쉽고 간편하게 사용할 수 있는 프로그램으로서 향후 활용성이 높을 것으로 판단된다.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.34 no.3
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• pp.379-392
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• 2024

With the rapid increase in data, saving storage space and improving the efficiency of data transmission have become critical issues, making the research on the efficiency of data compression technologies increasingly important. Lossless algorithms can precisely restore original data but have limited compression ratios, whereas lossy algorithms provide higher compression rates at the expense of some data loss. There has been active research in data compression using deep learning-based algorithms, especially the autoencoder model. This study proposes a new side-channel analysis data compressor utilizing autoencoders. This compressor achieves higher compression rates than Deflate while maintaining the characteristics of side-channel data. The encoder, using locally connected layers, effectively preserves the temporal characteristics of side-channel data, and the decoder maintains fast decompression times with a multi-layer perceptron. Through correlation power analysis, the proposed compressor has been proven to compress data without losing the characteristics of side-channel data.

• Clinical and Experimental Reproductive Medicine
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• v.36 no.4
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• pp.301-310
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• 2009

Objective: To compare the embryonic development and pregnancy results using sperms retrieved from fresh and frozen-thawed testicular tissue in patients with obstructive (OA) and non-obstructive azoospermia (NOA). Methods: A total two hundred twenty-two cycles of TESE-ICSI were performed in OA and NOA. Sperms were retrieved from fresh and frozen-thawed testicular tissue. ICSI was performed patient's own sperm. Fertilization was assessed 16~18 hrs after ICSI. Embryo development and pregnancy rates were analysed. Results: The fertilization rates were significantly different between OA and NOA patients (75.2% vs. 56.7%, p<0.05), however, embryo development did not differ between the groups (96.9% vs. 98.0%). Likewise, OA and NOA groups had no differences in their clinical pregnancy and delivery rates, 33.9% vs. 36.0% and 28.1% vs. 28.0%, respectively. With regard to sperm retrieved from fresh testicular tissue, fertilization rates were significantly different between the OA and NOA groups (76.4% vs. 52.9%, p<0.05); however, embryo development, clinical pregnancy and delivery rates were not different. For sperm retrieved from thawed testicular tissue, the fertilization rates were significantly different between the two groups (74.7% OA group vs. 65.6% NOA group, p<0.05); however, embryo development, clinical pregnancy and delivery rates were not different. Conclusions: Embryo development and clinical pregnancy did not differ in patients with obstructive and non-obstructive azoospermia, whether sperm retrieved from fresh and thawed testicular tissue were used, although the fertilization rates were different. Therefore, ICSI with sperm retrieved from fresh and thawed testicular tissue could achieve relevant clinical pregnancy results in patients with azoospermia.

• Clinical and Experimental Reproductive Medicine
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• v.36 no.1
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• pp.55-61
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• 2009

Objective: To compare the clinical outcomes of ICSI with sperm retrieved from testicular tissue in patients with obstructive azoospermia (OA) or hypospermatogenesis (HS). Methods: From January 2003 through December 2006, 155 patients with OA (241 cycles) and 28 patients with HS (34 cycles) were included in this study. We compared clinical outcomes of ICSI with testicular sperm such as fertilization rate, implantation rate, clinical pregnancy rate and delivery rate. Data were statistically analyzed using t-test and ${\chi}^2$-test. Results: Testicular spermatozoa could not be retrieved in 1 out of the 21 cycles where fresh testicular sperm extraction in HS patients. Fertilization rate (FR) was significantly higher in OA than HS (75.6 % vs. 62.6%, p<0.001). Cleavage rate (CR) per fertilized zygote was also significantly higher in OA than that in HS (66.8% vs. 54.8% p<0.001). However, there were no significant differences in good embryo rate (GER), clinical pregnancy rate (CPR), implantation rate (IR) and delivery rate (DR). Conclusion: Our results show that testicular sperm of HS does not affect CPR, IR, and DR although it has shown reduced FR and CR.

• Parasites, Hosts and Diseases
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• v.28 no.4
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• pp.241-252
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• 1990

In a basic attempt to develop the prophylactic and therapeutic measures on intestinal giantcystic disease of the Israel carp, C), prinks carpio nudum, the effects of physical and chemical factors on viability or survival of the spores of Thelchcnellus kiteuei were checked in vitro by means of extrusion test on the polar filament. When the fresh spores suspended with 0.45% and 0.9% scdium chloride solution and distilled water were laid at $5^{\circ}C$ and $28^{\circ}C$ for short terms, the extrusion rates increased until the 3rd day, meanwhile when son;e of them were suspended with Tyrode's solution at $-70^{\circ}C$ the rates increased gradually until the 8th day. Viabilities of the spores suspended with 0.9% saline and added antibiotics to the suspension at $5^{\circ}C$ for long terms lasted for 997 days and 1, 256 days (presumed values) at maximum, respectively. The spores suspended with distilled water at $28^{\circ}C$ for long terms survived 152.4 days, but the spores suspended with Tyrode's solution at $-70^{\circ}C$ for long terms showed almost the same viable pattern as early freezing stages up to 780 days. The spores suspended with Tyrode's solution, frozen at $-70^{\circ}C$ and thawed at $5^{\circ}C$, showed the highest rate of extrusion of the polar filament. In the case of frozen spores, the extrusion rates during heating tend to become higher in accordance with the increase of frozen period, and the critical points of 180 day-frozen spores to be killed were generally 78.5 hr. at $60^{\circ}C$, 23.4 hr. at $70^{\circ}C$, 189.1 min. at $80^{\circ}C$ or 10.5 min. at $90^{\circ}C$. The longer the spores were frozen, the more time was needed for the death of spores after thawing; 20 days-17.4 days, 100 days-33.2 days, and 400 days-37.8 days. The longer the spores were frozen, the more time was needed for the death of spores at a conventional when they were dried air drying condition, 540 days-23.5 days, 160 days-21.0 days, and 20 days-14.4 days. On the other hand, the longer the spores were frozen, the more spores were dead rapidly when they were irradiated with 10W UV-ray; 100 days-26.0 hr, 300 days-21.9 hr, and 540 days-13.9 hr. The time needed for killing 200 days-frozen spores by various disinfectants at 1, 000 ppd was 5.2 min. by calcium oxide, 10.4 min. by potassium permanganate, 27.8 min. by malachite green and 14.3 hr. by formalin. Transient inhibitory effects of the extrusion of the polar filament were observed by various antiprotozoal and antifungal agents in the descending order of ketoconazole. metronidasole and dapsone. The above results presume that full drying, followed by spraying CaO and maintaining sunny condition for a few days on the concrete bottoms of knish farm may be an effective method for the prevention of intestinal giant.cystic disease.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.398-399
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• 2001

A fungus. Penicillium sp. PS-113. with high phosphate-solubilizing activities was isolated from soil and tested the viability in POA medium supplemented with various concentrations of Trio in order to develop a dispersing agent for liquid formulation. Moreover, the number of Penicillium sp. PS-113 conidia, stored at $4^{\circ}C$ and $25^{\circ}C$ with Trio(0.1%) and various concentrations of additives($Cu^{++}$ $Mo^{++}$, bio-ceramic, Tween 80, PEG 200. diatomite. SDS), was counted on PDA at the intervals of 2 weeks. As a result, the liquid formulation containing 0.1 %( v/v) Trio was remarkably improved in dispersing ability and the viability of the conidia, and each of the supplements (0,01% $Mo^{++}$, 0.5% bio-ceramic. 1.0% Tween 80, 1.0% PEG 200) was similar to the 0.1% Trio.

• Journal of the Korean Society for Library and Information Science
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• v.46 no.3
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• pp.233-250
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• 2012

The purpose of this study is to assess the development, current states, and problems of MEDLIS document delivery service. With the analysis of MEDLIS transaction data from 2001 to 2011, we identified continuous usage decrease, unbalanced contribution by type of institution, high dependence on back issues, use differences among subfields of medicine, relatively low success rate, and various reasons for failure. Based on the results, recommendations for the maintenance of union catalog database, technical support for search capability enhancements, establishment of back issue archiving policy, user training and publicity, and membership expansion are suggested to promote the service.