• Food Science and Preservation
• /
• v.13 no.6
• /
• pp.774-782
• /
• 2006

This study investigated the hepatoprotective effects of an ethanol extract of lotus root (LRE) on alcohol-induced liver damage in rat. Sprague-Dawley rae weighing $100{\sim}150g$, were divided into 6 groups: basal diet group (BD), alcohol (35% 10 mL/kg/day) teated stoup (ET), LRE 200 mg/kg/day teated group (BD-LREL). LRE 400 mg/kg/day treated group (BD-LREH), LRE 200 mg/kg/day and alcohol treated group (ET-LREL), and LRE 400 3mg/kg/day and alcohol teated group (ET-LREH). After the administration, rats were sacrificed to get serum and liver to analyze antioxidant enzyme activity, glutathione and lipid peroxide contents. The body weight gain and feed efficiency ratio were decreased by alcohol administration, however, were gradually increased to a little lower level than the basal diet group by the combined administration of alcohol and LRE. The serum alanine aminotransferase (ALT), asparate aminotransferase (AST) and alkaline phosphatase (ALP) activities that were elevated by alcohol were significantly decreased by LRE administration. It was also observed that thiobarbituric acid reactive substances (TBARS) content, xanthine oxidase (XO), superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px) activities in liver that were increased by alcohol, were markedly decreased in the combined alcohol and LRE administered groups as compared with the alcohol administrated group. These effect of LRE within the alcohol groups were in a dose-dependent manner. The glutathione (GSH) content in liver was decreased by alcohol administration, however, increased after administering LRE. Teken together, these result suggest that ethanol extract of lotus root may have a possible protective effect on liver function in hepatotoxicity-induced rat by alcohol administration.

• Phonetics and Speech Sciences
• /
• v.12 no.1
• /
• pp.33-42
• /
• 2020

This study identified the substitution of /u/ for /o/ (e.g., pyəllo [pyəllu]) in Korean based on the speech corpus as a function of grammar items. Korean /o/ and /u/ share the vowel feature [+rounded], but are distinguished in terms of tongue height. However, researchers have reported that the merger of Korean /o/ and /u/ is in progress, making them indistinguishable. Thus, in this study, the frequency of the phonetic manifestation /u/ of the underlying form of /o/ for each grammar item was calculated in The Korean Corpus of Spontaneous Speech (Seoul Corpus 2015) which is a large corpus from a total of 40 speakers from Seoul or Gyeonggi-do. It was then confirmed that linking endings, particles, and adverbs ending with /o/ in the word-final position were substituted for /u/ approximately 50% of the stimuli, whereas, in nominal items, they were replaced at a frequency of less than 5%. The high rates of substitution were the special particle "-do[du]" (59.6%) and the linking ending "-go[gu]" (43.5%) among high-frequency items. Observing Korean pronunciation in real life provides deep insight into its theoretical implications in terms of speech recognition.

• Journal of Korea Society of Industrial Information Systems
• /
• v.25 no.6
• /
• pp.33-45
• /
• 2020

This paper aims to look at the perspective that the latest cutting-edge technologies are predicting individual diseases in the actual medical environment in a situation where various types of wearable devices are rapidly increasing and used in the healthcare domain. Through the process of collecting, processing, and transmitting data by merging clinical data, genetic data, and life log data through a user-participating wearable device, it presents the process of connecting the learning model and the feedback model in the environment of the Deep Neural Network. In the case of the actual field that has undergone clinical trial procedures of medical IT occurring in such a high-tech medical field, the effect of a specific gene caused by metabolic syndrome on the disease is measured, and clinical information and life log data are merged to process different heterogeneous data. That is, it proves the objective suitability and certainty of the deep neural network of heterogeneous data, and through this, the performance evaluation according to the noise in the actual deep learning environment is performed. In the case of the automatic encoder, we proved that the accuracy and predicted value varying per 1,000 EPOCH are linearly changed several times with the increasing value of the variable.

• Food Science and Preservation
• /
• v.21 no.5
• /
• pp.747-756
• /
• 2014

The objective of this study was to examine the effects of vitamin C on the formation of aflatoxin $B_1$ ($AFB_1$)-DNA adduct and $AFB_1$-induing cellular oxidative damage in rat livers treated with radiation and $AFB_1$. Six-week-old male Sprague-Dawley rats were randomly divided into five groups: the control group, the $AFB_1$-treated group, the group treated with $AFB_1$ and vitamin C, the group treated with X-ray and $AFB_1$, and the group treated with X-ray and $AFB_1$ with vitamin C. On the first day of the experiment, only one dose of X-rays was exposed to the entire liver at 1,500 cGy. Next, vitamin C was injected at 10 mg/kg body weight via intraperitoneal injection, followed an hour later by the administration of 0.4 mg/kg of $AFB_1$ via intraperitoneal injection. These treatments were administered every three days for 15 days. On the 16th day, the animals were sacrificed. The $AFB_1$ contents of the rat sera were determined via indirect competitive ELISA. In the quantitative analysis of $AFB_1$ in the rat sera via ELISA, $5.17{\pm}0.34ng/mL$ of $AFB_1$ was detected in the $AFB_1$-treated groups, but the amount decreased more significantly to $3.23{\pm}0.76ng/mL$ in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. The effect of vitamin C on $AFB_1$-DNA adduct formation was determined via ELISA. The values of $AFB_1$-DNA adduct formation were $9.38{\pm}0.41ng/mL$ in the $AFB_1$-treated groups, but the amount decreased more significantly to $5.28{\pm}0.32ng/mL$ in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. Immunohistochemistry revealed that the accumulation of the $AFB_1$ was not observed in the normal liver tissue (G1). The $AFB_1$-positive materials were observed in the central vein and the portal vein of the liver tissue from the $AFB_1$(G2) treatment or the X-ray and $AFB_1$(G4) co-treatment, but the $AFB_1$-positive materials were observed weakly in the group treated with vitamin C (G3 and G5). These results indicate that vitamin C had ameliorating effects on the $AFB_1$ accumulation of liver tissue.

• Journal of the Korean Institute of Telematics and Electronics S
• /
• v.35S no.11
• /
• pp.106-115
• /
• 1998

The performance of morphological image segmentation heavily depends on a proper selection of markers. In this paper, we propose a marker incubator where only a catchment basin that has grown sufficiently large through flooding simulation is registered as a marker. Marker incubator does following things at each flooding level; growing defined marker regions, finding new marker regions, and postponing irrelevant regions to be examined at the next level. The examination for a region to be a valid marker is performed by two size-oriented criterions that are derived from the structuring element size of a morphological filter. The simulation result shows that the image segmentation with the proposed marker incubator achieves the comparable image quality to Wang's method in a less number of markers even without region merging. Additionally, since the proposed method also performs better in terms of image quality and information for transmission, it is well suited for region-based image coding.

• Tunnel and Underground Space
• /
• v.14 no.6 s.53
• /
• pp.399-410
• /
• 2004

The utilization of AS(Artificial Intelligence) and Database could be considered as an useful access for the application of underground information from the point of a geotechnical methodology. Its detailed usage has been recently studied in many fields of geo-sciences. In this paper, the target of usage is on controlling the injection of grout which more scientific access is needed in the grouting that has been used a major method in many engineering application. As the proposals for this problem it is suggested the methodology consisting of a fuzzy-neural hybrid system and a database. The database was firstly constructed for parameters dynamically varied according to the conditions of rock mass during the injection of grout. And then the conceptional model for the fuzzy-neural hybrid system was investigated fer optimally finding the controlling range of the grout valve. The investigated model applied to four cases, and it is found that the controlling range of the grout valve was reasonably deduced corresponding to the mechanical phenomena occurred by the injection of grout. Consequently, the algorithm organizing the fuzzy-neural hybrid system and the database as a system can be considered as a tool for controlling the injection condition of grout.

• Childhood Kidney Diseases
• /
• v.6 no.1
• /
• pp.114-119
• /
• 2002

Takayasu's arteritis(TA) is a chronic idiopathic vasculitis mainly involving the aorta and its main branches, such as brachiocephalic, carotid, subclavian, vertebral and renal arteries, as well as coronary and pulmonary arteries The clinical features usually reflect limb or organ ischemia resulting from gradual stenosis of involved arteries. We experienced a case of idiopathic Takayasu's arteritis with negative tuberculin test involving multiple main branch arteries at active stage without pulse. We treated this patient with combined therapy of steroid and azathioprine, with remission of disease activity. (J Korean Soc Pediatr Nephrol 2002 ;6 : 114-9)

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.21 no.12
• /
• pp.2318-2324
• /
• 2017

Quantum cryptography, which is emerging as a next generation password, is being studied by quantum cryptographic transfer protocols and quantum secret communication. Quantum key transfer protocol can be used in combination with the modern password because of the inefficiency of the use of the password, or the use of OTP(one time password). In this paper an algorithm for direct communication by means of direct cryptographic communications rather than quantum keys. The method of implementing quantum secure direct community was adopted using 2-channel methods using Einstein gravity field. Two channels were designed to adopt a quantum secret communication protocol that applies time delay between 2-channels of channel to apply time difference between 2-channels. The proposed time delay effect reflects the time delay by reflecting the gravitational lensing phenomenon. Gravity generator with centrifugal acceleration is incorporated in the viscometer, and the time delay using this implies the correlation between the variance of the metametry.

• Journal of Digital Contents Society
• /
• v.19 no.9
• /
• pp.1727-1737
• /
• 2018

In this paper, we propose a system to detect spatial structures in land cover maps and to detect time-series spatial structure changes. At first, the proposed system detects patches in a certain area at different times and calculates their measures to analyse spatial structure patterns of the area. Then the system conducts patch mapping among the detected time-series patches and decides 6 types of patch changes such as keeping, creating, disappearing, splitting, merging, and changing in a mixed way. Also, the system stores the patch-based spatial structure patterns of time-series land cover maps in binary form to extract changes. This demonstrated that the proposed change detection system can be used as a basis for planning the reconstruction of the urban spatial structure by measuring the degree of urban sprawl.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2008.04a
• /
• pp.37-40
• /
• 2008

Many engineers find the way of improving the old building's structural behavior in the remodeling project which is performed using artificial openings for merging two houses. This test was performed to verify the characteristics of coupling beams according to the shape of the openings. One of test specimen has rectangle shape and the other was made by the circle shaped opening and one has coupling member only as slabs. Additionally, three specimens which have openings have 23% ratio in opening area to total wall area. Consequently, solid type which have no opening area shows shear failure. In the case of CW-RBS which have rectangular shaped opening, cracks are developed in coupling beam significantly. And CW-CS which has circular opening failed in shear showing development of diagonal cracks at wall toes and wall mid-height. It is thought that degradation of the wall strength is under the control of the opening shape and coupling beam-wall connection area.