• Title/Summary/Keyword: 병원산업

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Identification of Chrysanthemum Genetic Resources Resistant to Chrysanthemum Stunt Viroid (CSVd) (국화왜화바이로드 저항성 국화 유전자원 선발)

  • Park, S.K.;Choi, S.Y;Kwack, Y.B.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.22 no.1
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    • pp.131-142
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    • 2020
  • Chrysnathemum stunt viroid (CSVd), a small, single-stranded, infectious RNA, has caused a severe problem in chrysanthemum in the world. In Korea, since CSVd was firstly observed in 1997, the disease has been spread throughout the whole country rapidly. In spite of the seriousness, few methods for control of CSVd have been known without prevention. The use of resistant cultivars is one of the most efficient approaches for overcoming CSVd disease in chrysanthemum cultivation. This study was carried out to identify chrysanthemum genetic resources for the resistance to chrysanthemum stunt viroid (CSVd). A total of 192 commercial cultivars including 167 spray and 25 standard chrysanthemum were screened with CSVd through grafting inoculation method. In most of the inoculated cultivars, typical disease symptoms, stunting of plant height, reduced flower size, and flower color bleaching, were induced. Several cultivars, however, were symptomless or showed delay in symptom expression. Of 192 chrysanthemum cultivars, two cultivars with less than 5% of the average reduction rate of plant height, 'Chiwerel' and 'Jeongheungdaesin', were rated as resistant. And six cultivars less than 20% inculding 'Inga' were rated as moderate resistant. The remaining 184 cultivars with a high level of reduction were rated as susceptible. We expect that these genetic resources can be used in crossbreeding programs for developing CSVd resistant cultivars of chrysanthemum.

Enhanced Antibacterial Activity of Sodium Hypochlorite under Acidic pH Condition (산성 pH 조건에서 차아염소산나트륨의 항균 활성 향상)

  • Son, Hyeon-Bin;Bae, Won-Bin;Jhee, Kwang-Hwan
    • Microbiology and Biotechnology Letters
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    • v.50 no.2
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    • pp.211-217
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    • 2022
  • Sodium hypochlorite (NaClO) is a disinfectant widely used in hospitals and food industries because of its antimicrobial activity against not only bacteria but also fungi and virus. The antibacterial activity of NaClO lies in the maintenance of a stable hypochlorous acid (HClO) concentration, which is regulated by pH of the solution. HClO can easily penetrate bacterial cell membrane due to its chemical neutrality and the antibacterial activity of NaClO is thought to depend on the concentration of HClO in solution rather than hypochlorite ions (ClO-). In this study, we investigated the antibacterial activity of NaClO according to pH adjustment by means of time kill test and assays of Reactive Oxygen Species (ROS) and adenosine triphosphate (ATP) concentration changes before and after NaClO treatment. We also investigated that the degree of cell wall destruction through field emission scanning electron microscopy (FE-SEM). Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) exposed to 5 ppm NaClO at pH 5 exhibited 99.9% mortality. ROS production at pH 5 was 48% higher than that produced at pH 7. In addition, the ATP concentration in E. coli and S. aureus exposed to pH 5 decreased by 94% and 91%, respectively. As a result of FE-SEM, it was confirmed that the cell wall was destroyed in the bacteria by exposing to pH 5 NaClO. Taken together, our results indicate that the antibacterial activity of 5 ppm NaClO can be improved simply by adjusting the pH.

Evaluation of 3D Printing Filaments for Radiation Shielding using High Density Polyethylene and Bismuth (고밀도 폴리에틸렌과 비스무트를 이용한 3D 프린팅용 방사선 복합필라멘트 개발 및 차폐능력 평가)

  • Park, Ki-Seok;Kim, Dong-Hyun
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.233-240
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    • 2022
  • Research on the presence or absence of radiation shielding for FDM-type filaments has recently begun to be studied, but filaments with shielding capabilities are not sold in Korea, and not studies yet. Therefore, in this research, we will use HDPE (High Density Polyethylene) as a base material, select bismuth as a reinforcing material to manufacture a composite filament, evaluate the shielding ability, and provide basic data for the development of a radiation shielding composite material using 3D printing.A filament is produced by mixing Bismuth with an effective atomic number 83 with HDPE of PE series and adjusting the content of Bismuth to 20% wt, 30% wt, 40% wt. Compounded filaments were evaluated for their physical properties and shielding capabilities by ASTM evaluation methods. As the bismuth content increases, the density, weight, and tensile strength increase, and the shielding capacity is confirmed to be excellent. As a result of the radiation shielding capacity evaluation, it was confirmed that HDPE (80%) + Bi (20%) showed a shielding rate of 82% at 60 kV and a shielding rate of up to 94% or more at 40% bismuth content. In this study, we confirmed that it was possible to produce a radiation shield that is lighter than the metal particle-containing filaments. Furthermore, that have been shield radiation by using HDPE + Bi filaments, and radiation in the medical and radiation industries. The possibility of using it as a shielding complex was confirmed.

A study on the change in the perception of funeral culture among the elderly (노인의 장례문화 인식변화에 대한 연구)

  • Song, Hyeon-Dong;Kim, Seol-Hee;Kim, Kwang-Hwan;Ku, Jin-Hee
    • Journal of Digital Convergence
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    • v.20 no.5
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    • pp.671-680
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    • 2022
  • The purpose of this study is to suggest the direction of the funeral culture industry suitable for the age of longevity and well-aging through a study on changes in the perception of funeral culture among the elderly. The survey of this paper was conducted by Gallup Korea, and the survey method was a 1:1 individual interview using a structured questionnaire. The survey was conducted from October 1 to October 25, 2021, targeting 127 elderly people over the age of 65 living in Seoul, Incheon, and Gyeonggi-do. The number of valid subjects was 110, and the sampling method used was allocation by sex/age/income level/religion. As a result of the study, as for the change in the perception of funeral culture among the elderly, women preferred cremation to men (p=0.034). It was investigated that the level of income (p=0.004) and religious status (p=0.020) had an effect on funerals while alive. According to the presence or absence of thoughts about death, there was a significant difference in the membership of the mutual aid product (p=0.008) and the intention to return to a religious organization (p=0.004) when a memorial service was held. The results of this study are expected to be usefully utilized in presenting the direction and policy of the funeral culture industry suitable for the age of well-aging in the future.

Social Network Analysis of Long-term Standby Demand for Special Transportation (특별교통수단 장기대기수요에 대한 사회 연결망 분석)

  • Park, So-Yeon;Jin, Min-Ha;Kang, Won-Sik;Park, Dae-Yeong;Kim, Keun-Wook
    • Journal of Digital Convergence
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    • v.19 no.5
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    • pp.93-103
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    • 2021
  • The special means of transportation introduced to improve the mobility of the transportation vulnerable met the number of legal standards in 2016, but lack of development in terms of quality, such as the existence of long waiting times. In order to streamline the operation of special means of transportation, long-term standby traffic, which is the top 25% of the wait time, was extracted from the Daegu Metropolitan Government's special transportation history data, and spatial autocorrelation analysis and social network analysis were conducted. As a result of the analysis, the correlation between the average waiting time of special transportation users and the space was high. As a result of the analysis of internal degree centrality, the peak time zone is mainly visited by general hospitals, while the off-peak time zone shows high long-term waiting demand for visits by lawmakers. The analysis of external degree centrality showed that residential-based traffic demand was high in both peak and off-peak hours. The results of this study are considered to contribute to the improvement of the quality of the operation of special transportation means, and the academic implications and limitations of the study are also presented.

Correlation and Spatial Analysis between the number of Confirmed Cases of the COVID-19 and Traffic Volume based on Taxi Movement Data (택시 이동 데이터 기반 COVID-19 확진자 수와 교통량 간의 상관관계 및 공간분석)

  • Jeon, Seung Bae;Kim, Geon;Jeong, Myeong-hun
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.39 no.6
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    • pp.609-618
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    • 2021
  • The spread and damage of COVID-19 are putting significant pressure on the world, including Korea. Most countries place restrictions on movement and gathering to minimize contact between citizens and these policies have brought new changes to social patterns. This study generated traffic volume data on the scale of a road network using taxi movement data collected in the early stages of the COVID-19 third pandemic to analyze the impact of COVID-19 on movement patterns. After that, correlation analysis was performed with the data of confirmed cases in Daegu Metropolitan City and Local Moran's I was applied to analyze the effect of spatial characteristics. As a result, in terms of the overall road network, the number of confirmed cases showed a negative correlation with taxi driving and at least -0.615. It was confirmed that citizens' movement anxiety was reflected as the number of confirmed cases increased. The commercial and industrial areas in the center of the city confirmed the cold spot with a negative correlation and low-low local Mona's I. However, the road network around medical institutions such as hospitals and spaces with spatial characteristics such as residential complexes was high-high. In the future, this analysis could be used for preventive measures for policymakers due to COVID-19.

Biochemical Properties and Application of Bacteriocins Derived from Genus Bacillus (Bacillus속 세균 유래 박테리오신의 특성과 응용)

  • Ji-Young Lee;Dae-Ook Kang
    • Journal of Life Science
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    • v.33 no.1
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    • pp.91-101
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    • 2023
  • Bacteriocins are antimicrobial peptides synthesized on ribosomes, produced by bacteria, that inhibit the growth of similar or closely related bacterial strains. Since the discovery of nisin, many bacteriocins with unique structures and various modes of antibacterial activity have been described, and genes encoding production, secretion, and immunity have been reported. Nisin is one of the bacteriocins applied in cheese, liquid eggs, sauces and canned foods. Many of the bacteriocins of the genus Bacillus belong to lantibiotics, which are modified peptides after translation. Other genus Bacillus also produce many non-lantibiotic bacteriocins. Bacteriocins of the genus Bacillus are sometimes becoming more important because of their broader antibacterial spectrum. Bacteriocins are considered attractive compounds in the food and pharmaceutical industries to prevent food spoilage and growth of pathogenic bacteria. Bacteriocins can be used as biological preservatives in a variety of ways in the food system. Biopreservation refers to extending shelf life and improving safety of foods using microorganisms and/or their metabolites. The demand for new antimicrobial compounds has generated great interest in new technologies that can improve food microbiological safety. Applications of bacteriocins are expanding from food to human health. Today, many researchers are shifting their interest in bacteriocins from food preservation to the treatment of bacteria that cause infections and antibiotic-resistant diseases. This exciting new era in bacteriocin research will undoubtedly lead to new inventions and new applications. In this review, we summarize the various properties and applications of bacteriocins produced by the genus Bacillus.

It Was Possible to Reduce the Pain of the Victims of Humidifier Disinfectant (가습기살균제 피해자의 아픔을 줄일 수 있었다)

  • Kim, Pangyi;Choi, Yoon-Hyeong;Park, YeongChul;Park, Tae-Hyun;Leem, JongHan
    • Journal of Environmental Health Sciences
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    • v.48 no.1
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    • pp.1-8
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    • 2022
  • Objectives: The purpose of this study is to reveal the circumstances under which the cases of harm to health caused by humidifier disinfectant were neglected and show the points where the number of victims and the degree of damage could have been reduced. In addition, it attempts to describe how damage management proceeded immediately after the incident and actually exacerbated the damage. Finally, it explores the unfortunate aspects of the recent trial. By doing so, it attempts to take this as an opportunity to consider whether a tragic event such as the humidifier disinfectant incident could occur in the future. Methods: This study collected and analyzed data on chemical material characteristics related to humidifier disinfectants, data on health effect characteristics, data on related laws and regulations from the Ministry of Environment, data related to the damage investigation by the Korea Environmental Industry and Technology Institute, and current contents. Results: The lack of related systems and laws is the area where the greatest responsibility for the cause of the humidifier disinfectant disaster falls, so it is difficult for the government to escape this responsibility. Establishing a dedicated department to identify the prevalence of certain diseases within the functions of the Health Insurance Review and Assessment Service to monitor health can greatly contribute to the prevention and management of diseases through early detection and management of group outbreaks caused by harmful factors. Humidifier disinfectant damage relief should have been expanded earlier beyond HDLI (humidifier disinfectant lung injury) to include non-specific diseases such as asthma, pneumonia, and interstitial pneumonia. The scope of relief benefits should have also been expanded earlier to include the payment of disability benefits. Fortunately, with the 2020 revision of the Special Act, the conditions for estimating causal relations were eased and individual screening systems such as health impact assessment were reorganized along with the introduction of a rapid screening system. Conclusions: The management system for chemical substances in a country is clearly of paramount importance, and the ministry in charge must have a response system in case of damage to health effects. Administration that looks at the victims' situation from their point of view is needed, and technical countermeasures are required to quickly recognize the prevalence of certain diseases.

Development of Functional Halogenated Phenylpyrrole Derivatives (기능성 할로겐화 페닐피롤 )

  • Min-Hee Jung;Hee Jeong Kong;Young-Ok Kim;Jin-Ho Lee
    • Journal of Life Science
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    • v.33 no.10
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    • pp.842-850
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    • 2023
  • Pyrrolnitrin, pyrrolomycin, and pyoluteorin are functional halogenated phenylpyrrole derivatives (HPDs) derived from microorganisms with diverse antimicrobial activities. Pyrrolnitrin is a secondary metabolite produced from L-tryptophan through four-step reactions in Pseudomonas fluorescens, Burkholderia cepacia, Serratia plymuthica, etc. It is currently used for the treatment of superficial dermatophytic fungal infections, has high antagonistic activities against soil-borne and foliar fungal infections, and has many industrial applications. Since pyrrolnitrin is easily decomposed by light, it is difficult to widely use it outdoors. As an alternative, fludioxonil, a synthetically produced non-systemic surface fungicide that is structurally similar and has excellent light stability, has been commercialized for seed and foliar treatment of plants. However, due to its high toxicity to aquatic organisms and adverse effects in human cell lines, many countries have established maximum residue levels and strictly control its levels. Pyrrolomycin and pyoluteorin, which have antibiotic/antibiofilm activity against Gram-positive bacteria and high anti-oomycete activity against the plant pathogen Pythium ultimum, respectively, were isolated and identified from microorganisms. This review summarizes the biosynthesis and production of natural pyrrolnitrin derived from bacteria and the characteristics of synthetic fludioxonil and other natural phenylpyrrole derivatives among the HPDs. We expect that a plethora of highly effective, novel HPDs that are safe for humans and environments will be developed through the generation of an HPD library by microbial biosynthesis and chemical synthesis.

Analysis of Mediating Effect of Skin Care Self-Management in the Relationship between Self-Efficacy and Business Performance of Skin Care Workers' Grit (피부미용 종사자의 그릿이 자기효능과 직무성과에 미치는 영향: 자기관리의 매개효과 분석)

  • Gyu-Rang Kim
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.6
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    • pp.1506-1520
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    • 2023
  • The purpose of this study was to analyze the mediating effect of self-management in the relationship between the grit of skin care workers and its impact on self-efficacy and job performance. Research participants were 344 workers at skin care shop and hospitals in Seoul and Gyeonggi province, and data were collected through a structured questionnaire. The collected data were analyzed through descriptive statistics, confirmatory factor analysis(CFA), correlation analysis, structural equation model, and mediation effect analysis using bootstrapping method using SPSS, AMOS 26.0 Statistical programs. The conclusions drawn through a series of research procedures are as follows. First, the grit of skin care workers showed a significant positive(+) influence on self-management, self-efficacy, and job performance. Second, Self-management of skin care workers showed a significant positive(+) relationship with self-efficacy and job performance. Third, self-management of skin care workers was found to have a mediating effect in the relationship between grit and job performance. Therefore, it is judged that there is an urgent need to apply human resources management and education programs that can increase self-management, self-efficacy, and job performance through cultivating the grit of beauty industry workers.