• Proceedings of the KIEE Conference
• /
• 1999.07b
• /
• pp.674-676
• /
• 1999

At present electrical and electronic technologies is rapidly improved, and they have formed their market widely. New technologies such as traffic signal system, navigation system and unmanned vehicle are connected with transportation field. Among these advanced technologies, the Image Processing Technology has been used for the astro-navigation, medicine, military field and so forth. Recently The Image Processing Technologies are widely applied to traffic enforcement system for signal, speed limit and HOV lane. In this study we developed the advanced enforcement system for over limit(overweight)vehicles using Image Processing System.

• Journal of Korean Medical classics
• /
• v.23 no.3
• /
• pp.13-21
• /
• 2010

"소변불리(小便不利)" "상한론(伤寒论)", "금궤요략(金匮要略)"의 수많은 원문(原文)에 기재되어 있지만 원문(原文)전체에 흩어져 있으며 그에 대한 자세한 해석 또한 논술되어있지 않다. 그리하여 본 논문은 "상한론(伤寒论)"과 "금궤요략(金匮要略)"중의 기재된 소변불리(小便不利)의 원문(原文)만을 체계적으로 정리하여 총결해 놓았다. 우선, 장중경(张仲景)이 말하는 소변불리(小便不利)를 범주화하여 병인, 병기, 치법, 방약의 정리분석을 통해, 소변불리(小便不利)가 단순한 증상만이 아닌 소변(小便)의 정황(情況)을 근거로 진액(津液)소갈의 정도, 방광(膀胱)의 기화(氣化)상태및 치료효과의 반응 등을 포괄한 것임을 주장하였으며, 장중경변치소변불리(张仲景辨治小便不利)의 치료법(治疗法)이 상한육경변증이론연구(伤寒六经辨证理论硏究와 잡병진단치료(杂病诊断治疗)중에 중요한 요소임을 전면적으로 논술하였다. 또한 근대의가(近代醫家)의 의안(醫案)의 문헌연구와 소변불리(小便不利)의 근대임상치료(近代臨床治療) 사례를 근거하여 장중경(张仲景)이 중시하는 인체수액대사(人体水液代谢)와 기화공능(气化功能)이 비뇨기 질병과 합병증으로 인한 소변불리(小便不利)증상 치료의 수준을 높일 수 있으며, 소변불리(小便不利)의 치료과정을 통하여 현대질병치료의 효과를 판단 할 수 있는 기준이 될 뿐만 아니라 그에 따른 예방의학의 충분한 이론근거가 됨을 정리하였다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2000.04a
• /
• pp.934-938
• /
• 2000

인터넷 웹 기반 교수-학습체제는 학습자 위주의 교육환경으로 변화하였고, 웹 환경에서도 학습자에게는 시간과 공간의 제약에서 벗어나 다양한 교육정보를 접할 수 있는 원격교육시스템이 대두하고 있다. 인터넷의 발달은 교육환경에도 많은 변화를 가져오고 있다. 이러한 변화는 인터넷을 이용한 웹기반 원격교육이 여러 분야에서 폭넓게 응용되고 있음을 대변하는 것이라 할 수 있다. 하지만 기존의 원격강의시스템의 경우 교사가 학습할 내용들을 파일형태로 업로드해 놓으면 학습자가 다운로드하여 쓰는 방식이어서 많은 전송비용과 강의내용 구성이 단순한 텍스트 위주의 형태로 구성되어 학습자의 학습효과가 의문시 되었다. 이는 학습자 위주의 자기 주도학습에 많은 어려움을 유발시켰다. 따라서, 본 논문에서는 고등학교 정보산업교과의 [인터넷] 단원에 대한 학습을 체계적으로 언제 어디서나 학습할 수 있도록 이론과 실기강의내용을 웹을 통하여 교육에서 요구되는 음성과 교재 판서의 기능을 웹상에서 구현할 수 있도록 되어 있다. 이런 멀티미디어 자료들이 동기화되어 자기 주도적 학습을 할 수 있는 멀티미디어 원격강의시스템을 구현하였다. 본 연구의 원격강의시스템은 멀티미디어자료 들을 활용한 원격강의시스템이기 때문에 개별화된 교육과 자기 주도적 학습을 통해 시ㆍ공간의 제약을 받지 않고 학습 할 수있는 진정한 원격강의시스템이다.

• Tuberculosis and Respiratory Diseases
• /
• v.45 no.5
• /
• pp.962-974
• /
• 1998

Background: Alteration of p53 tumor suppressor genes is most frequently identified in human neoplasms, including lung carcinoma. It is well known that bcl-2 oncoprotein protects cells from apoptosis. Recent studies have demonstrated that bcl-2 expression is associated with favorable prognosis for patients with non-small cell lung carcinoma. However, the precise biologic role of bcl-2 in the development of these tumors is still obscure. p53 and bcl-2 have important regulatory influence in the apoptotic pathway and thus their relationship is of interest in tumorigenesis, especially lung cancer. Purpose: The author investigated to know the prognostic significance of the expression of p53 and bcl-2 in radically resected non-small cell lung cancer. Method: 84 cases of formalin-fixed paraffin-embedded blocks from resected primary non-small cell lung cancer from 1980 to 1994 at Hanyang University Hospital were available for both clinical follow-up and immunohistochemical staining using monoclonal antibodies for p53 and bcl-2. Results : The histologic classification of the tumor was based on WHO criteria., and the specimens included 45 squamous cell carcinomas(53.6%), 28 adeonocarcinomas(33.3%) and 11 large cell carcinomas(13.1 %). p53 immunoreactivity was noted in 47 cases of 84 cases(56.0%). bcl-2 immunoreactivity was noted in 15 cases of 84 cases(17.9%). The mean survival duration was $64.23{\pm}10.73$ months in bcl-2 positive group and $35.28{\pm}4$. 39 months in bcl-2 negative group. The bcl-2 expression was significantly correlated with survival in radically resected non-small cell lung cancer patients(p=0.03). The mean survival duration was $34.71{\pm}6.12$ months in p53 positive group and $45.35{\pm}6.30$ months in p53 negative group(p=0.21). The p53 expression was not predictive for survival. There was no correlation between combination of the different status of p53 and bcl-2 expression in our study. Conclusions : The interaction and the regulation of new biologic markers, such as those involved in the apoptotic pathway, are complex. bcl-2 overexpression is a good prognostic factor in non-small cell lung cancer and p53 expression is not significantly associated with the prognostic factor in non-small cell lung cancer.

• Journal of Animal Environmental Science
• /
• v.2 no.1
• /
• pp.27-39
• /
• 1996

A survey was conducted for dairy farmer to estimate the optimum number of machine and equipment in 1994. Labor hours, operation costs and operation methods for each dairy processing were investigated and analyzed for the farmers to find the expected numbers of machine and equipment on the basis of the desired farm scale. And also, the estimated models were compared and analyzed with the conventional models which more than half dairy farmers used bucket milker in tie stall barn. Some of the results are as follows : 1. Analysis results of conventional model showed that a dairy farm could raise to 15 heads of dairy cow with family labor of 1.5 men, labor hours of 2, 700 in you and total operation costs of 734 thousand won per head. 2. The result, used in conjunction with minimum operation costs in tie stall barn, showed that 28 dairy cows could be raised by using concentrates feeding by hoppers, water supply by water cups, milking by pipeline milker, and manure cleaning by barn cleaner with total operation costs of 520 thousands won per head. 3. The total operation costs of a loose barn system is higher than those of tie stall barn system to raise about 30 heads. For the loose barn system, the herringbone parlour was used for milking, concentrate feeding by automatic concentrate feeder, water supply by thermal insulation feeder, and manure cleaning by scraper with total operation costs of 582 thousands won per head every year.

• Journal of Gastric Cancer
• /
• v.9 no.4
• /
• pp.193-199
• /
• 2009

Purpose: The aim of this study was to evaluate the clinicopathologic features, treatment outcomes, and prognostic factors of gastric cancer based on 14 years' experience in a single medical center, and to compare treatment outcomes with a previous study. Materials and Methods: We retrospectively studied 2,327 patients who were operated on for gastric cancer between 1993 and 2006 at Korea University Hospital. Results: The resection rate was 92.8% and curative resection was achieved for 1,960 (90.8%) patients. The 5-year survival rate was 70.0% for all patients undergoing resection and 79.2% for patients undergoing curative resection. The 5-year survival rate was 1.5% for unresected cases. Age, tumor size, location of the tumor, gross tumor type, depth of tumor invasion, lymph node involvement, distant metastasis, tumor stage, combined resection, complications, histology, and type of operation each had prognostic significance on univariate analysis. On multivariate analysis, lymph node involvement, depth of invasion, venous invasion, and age were independent prognostic factors. Conclusion: The 5-year survival rate for patients who underwent curative resection was 79.2%. Depth of invasion, lymph node involvement, venous invasion, and age were independent prognostic factors. The fact that tumor stage is the most important prognostic factor after curative resection, increases the importance of early detection.

• Proceedings of the KSCN Conference
• /
• 2003.11a
• /
• pp.1079-1079
• /
• 2003

최근 노인인구의 증가와 함께 식생활의 변화에 의해 사망원인의 변화가 일어나고 있다 한국인의 주요 사망원인 중 뇌혈관 및 심장질환 등 순환기계 질환에 의한 사망이 증가하고 있는 추세이며, 심장순환계 질환의 위험요인인 고혈압의 이환률도 65세 이상 노인에게서 증가하고 있다. 고혈압은 만성질환으로 산화적 스트레스를 증가시키는 질환이므로 본 연구에서는 건강한 노인과 고혈압 노인의 체내 항산화 영양상태를 비교하기 위해 울산지역 50세 이상 노인을 대상으로 하였다. 대조군은 질환이 없거나 골다공증, 위장질환과 같은 기타 질환을 가진 사람 96명이었으며, 고혈압환자군은 고혈압을 가진 모든 질환자 118명이었고, 항산화 영양소 섭취나 혈장내 항산화 영양상태에 영향을 미치는 성별, 연령, 흡연 및 음주상태를 보정하여 비교하였다. 고혈압환자의 평균 유병기간은 6.1년이었으며, 항산화 비타민 섭취량은 비타민 A, retinol, $\beta$-carotene과 비타민 C 섭취량 모두 고혈압 유무에 따른 유의적인 차이가 나타나지 않았으나 고혈압환자의 섭취량이 높은 경향을 보였다. 한국인영양권장량과 비교한 결과 대조군의 비타민 A 섭취는 권장량의 86.2%, 고혈압환자군은 권장량의 103.0%를 섭취하여 고혈압군에서 유의적으로 높았고, 권장량의 75% 이하 섭취자의 비율은 대조군에서 46.9%, 고혈압군에서 41.5%로 조사되었다. 비타민 C 섭취는 대조군에서 권장량의 176.6%, 고혈압군에서는 189.0%로 나타나 질환의 유무에 관계없이 두 군 모두 권장량의 170%이상을 섭취하고 있었으나 권장량의 75% 이하를 섭취하는 사람의 비율이 대조군에서 13.5%, 고혈압군에서 17.0%로 고혈압군에서 높게 나타났다. 혈장 비타민 C의 농도는 대조군 15.3 mg/L, 고혈압환자 15.9mg/L, 혈장 $\beta$-carotene 농도는 대조군 0.21mg/L, 고혈압환자 0.22 mg/L로 나타나 고혈압 유무에 따른 차이가 없었고, 혈장 비타민 A,E 농도 및 총 항산화능력은 대조군에 비해 고혈압환자에게서 유의적으로 높게 나타났다. 또한 혈장 지질과산화물의 농도도 유의적이지는 않지만 고혈압환자에게서 높은 경향이 나타났다. 따라서 고혈압에 따른 항산화 영양상태를 비교한 결과 전반적인 항산화 비타민의 섭취량, 혈중 비타민 농도 및 총 항산화능력이 예상과 달리 대조군 보다 고혈압환자에게서 유의적으로 높게 나타났다. 이런 결과는 질환자들이 자신이 가진 질병의 진전을 막거나 치료의 목적으로 치료제를 복용하고, 식이요법을 실시하고 있기 때문으로 사료되며, 고혈압과 같이 산화적 스트레스가 증가하는 질환의 경우 체내 항산화 체계 반응이 이러한 변화에 효율적으로 대처하기 위한 방향으로 증가되었을 가능성이 있을 것으로 사료된다. 특히, 본 연구의 대상자들의 유병기간이 6.1년으로 비교적 길기 때문에 질환의 진행정도에 따른 항산화 상태를 측정하거나 비교적 질환으로 판정된 직후의 사람들의 대상으로 한 연구 등 더 많은 연구가 필요하다.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.38 no.4
• /
• pp.291-297
• /
• 2018

This study was conducted to investigate the effects of feeding system and NDF levels of TMR on blood metabolites in Holstein heifers. Fifty heifers were assigned to one of five treatments according to feed type and level of NDF: TMR (total mixed ration), CON (concentration + mixed forage), T1 (${\geq}53%$ NDF), T2 (50~53% NDF), and T3 (${\leq}50%$ NDF). Although GLU concentrate was not effected by feed type, increased significantly as the level of NDF decreased. There was no effect on concentrate of blood metabolite related with protein. As the level of NDF decreased, the blood ALB concentration was increased (p<0.05). The concentration of blood CHOL was higher in CON than those of TMR (p<0.05), and increased as the level of NDF decreased. The concentration of blood lipid was higher in CON than those of TMR and increased at lower level of NDF. The concentration of blood ALT were significantly lower in T3 than T1 and T2 (p<0.05). Thus, the results of this study suggest that the feeding system and NDF level may affect the blood metabolite concentration; however, the feed intake and other nutrient levels should also be considered.

• Tuberculosis and Respiratory Diseases
• /
• v.44 no.6
• /
• pp.1285-1295
• /
• 1997

Background : EGFR is one of the initial step in signal transduction pathway about multistep carcinogenesis. It is homologous to oncogene erbB-2 and is the receptor for EGF and TGF alpha. EGFR has important role in the growth and differentiation of tumor cells. So, EGFR in non-small cell lung cancer was examined to search for possible evidence as clinical prognostic factor. Methods : To investigate the role of EGFR in lung cancer, the author performed immunohistochemical stain of EGFR on 57 resected primary non-small cell lung cancer specimens. And the author analyzed the correlation between EGFR expression, clinical parameters, Sand $G_1$ phase fraction and survival. Results : 1) EGFR were detected in 56% of total 57 patients (according to histologic type, squamous cancer 50%, adenocarcinoma 63%, large cell cancer 75%) (according to TNM stage, stage I 64%, stage II 38%, stage III 55%) (according to cellular differentiation, well 50%, moderately 52%, poorly 65%). All differences were insignificant 2) Using the flow cytometric analysis, mean S-phase fraction of EGFR (+) and (-) group were 22.3(${\pm}10.5$)%. 18.0(${\pm}10.9$)% (p>0.05), mean $G_1$-phase fraction of EGFR (+) and (-) group were 68.4(${\pm}11.6$)%, 71.1(${\pm}12.8$)%, (p>0.05) 3) Two-year survival rate of EGFR (+) and (-) group were 53%, 84%, median survival time of EGFR (+) and (-) group were 26, 53 months. (p<0.05, Kaplan-Meier, generalized Wilcox) Conclusion : EGFR immunostaining may be a simple and useful method for survival prediction in non-small cell lung cancer.

• Korean Journal of Construction Engineering and Management
• /
• v.7 no.6
• /
• pp.132-140
• /
• 2006

On December, 1996, Construction Management(CM) was introduced in Korean construction industry due to its managerial efficiency proven in the international construction industries. However, It have had serious problems with many regulations, standards, manuals and details of practices considering its constituents and industry conditions. Especially, there were controversial points in the CM fee estimate; difference between the fee on the owner's view point and that from contractor's that impedes appropriate CM services. Therefore, this paper is to analyze public construction projects into Cm fee calculation such as fee as a percent of construction cost, cost plus fixed fee and contract price, and analyzed what is irrationality and why irrationality is made. So it makes a contribution to a study on standards for paper CM fee calculation.