• Radiation Oncology Journal
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• v.24 no.4
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• pp.272-279
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• 2006

$\underline{Purpose}$: This study investigated the influence of irradiation and cisplatin on PrxI & PrxII expression and on their survival rates (SR) in SK-N-BE2C and Rat2 cell lines. $\underline{Materials\;and\;Methods}$: The amount of PrxI & PrxII production with or without N-acetyl-L-cysteine (NAC) pretreatment was studied using a western blot after 20 Gy irradiation to determine the degree of inhibition of ROS accumulation. In addition, the amount of PrxI & PrxII production after cisplatin and after combination with cisplatin and 20 Gy irradiation was studied. The SRs of the cell lines in SK-N-BE2C and Rat 2 cells, applied with 20 Gy irradiation only, with various concentrations of cisplatin and with the combination of both, were studied. The 20 Gy irradiation-only group and the combination group were each subdivided according to NAC pretreatment, and corresponding SRs were observed at 2, 6, 12 and 48 hours after treatment. $\underline{Results}$: Compared with the control group, the amount of PrxI in SK-N-BE2C increased up to 60 minutes after irradiation and slightly increased after irradiation with NAC pretreatment 60 minutes. It did not increase in Rat2 after irradiation regardless of NAC pretreatment. PrxII in SK-N-BE2C and Rat2 was not increased after irradiation regardless of NAC pretreatment. The amounts of PrxI and PrxII in SK-N-BE2C and Rat2 were not increased either with the cisplatin-only treatment or the combination treatment with cisplatin and irradiation. SRs of irradiation group with or without NAC pretreatment and the combination group with or without NAC pretreatment were compared with each other in SK-N-BE2C and Rat2. SR was significantly high for the group with increased amount of PrxI, NAC pretreatment and lower the cisplatin concentration. SR of the group in SK-N-BE2C which had irradiation with NAC pretreatment tended to be slightly higher than the group who had irradiation without NAC pretreatment. SR of the group in Rat2 which had irradiation with NAC pretreatment was significantly higher than that the group which had irradiation without NAC pretreatment. Compared to the combination group, the irradiation-only group revealed statistically significant SR decrease with the maximal difference at 12 hours. However, at 48 hours the SR of the combination group was significantly lower than the irradiation-only group. $\underline{Conclusion}$: PrxI is suggested to be an antioxidant enzyme because the amount of PrxI was increased by irradiation but decreased pretreatment NAC, a known antioxidants. Furthermore, cisplatin may inhibit PrxI production which may lead to increase cytotoxicity of irradiation. The expression of PrxI may play an important role in cytotoxicity mechanism caused by irradiation and cisplatin.

• Journal of radiological science and technology
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• v.39 no.2
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• pp.157-161
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• 2016

The purpose of this study is that in measures the acoustic propagate characteristics and temperature sensitivity of ultrasound tissue mimicking phantom(TM phantom). TM phantom manufacture according to the International Electronical Committee(IEC) guidelines for acoustic propagate characteristics of soft tissue. TM phantom was observed to have the image brightness and the image depth penetration decreases changes convergence which was the subject of ultrasound image characteristics in accordance with an external temperature that the change is reduced in temperature below $22^{\circ}C$. This study provide a basis t o create another TM Phantom and TM Phantom has been determined that it is appropriate for use in more than $22^{\circ}C$.

• 대한두경부종양학회:학술대회논문집
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• 1990.11a
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• pp.26.1-26.1
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• 1990

• Proceedings of the KWS Conference
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• 2001.10a
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• pp.242-246
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• 2001

• 전기의세계
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• v.28 no.1
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• pp.5-14
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• 1979

비파괴검사방법에는 여러가지가 있는데 과거에는 주로 방사건 유도시험이 주역을 이루어 왔다고 볼수 있다. 그런데 최근에는 초음파를 이용한 탐상장치의 성능이 향상하였고 초음파를 이용하지 않으면 검사할수 없는 대상물의 검사가 필요하게 되었다는 점에 의하여 초음파의 이용이 상당히 급속하게 확대되어 그 응용범위도 수도관에서 원자연료까지 이루게 되었다. 그러나 방사선 투과식 시험에서는 검출곤란한 균열을 검출할 수 있는 기술적 특성및 고가인 소모품이 필요치 않고 또한 검사속도도 빠르다는 경제성에 주목하여 방사투과시험이 가능한 대상물에 대해서도 이용하게끔 되었다. 초음파에 의한 비파괴시험을 이용목적에 따라 분류하면 탐상과 계측으로 대별할 수 있다. 이하 이들의 각종방법에 대하여 순차적으로 그 개요를 설명하겠다.

• Journal of radiological science and technology
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• v.26 no.3
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• pp.19-24
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• 2003

We carried out studies on development and characteristic of ultrasound brast training biopsy phantom. the major finding were of follow ; (1) C type TMM was shown good homogeneity, brightness and attenuation as like human soft tissue. (2) $TiO_2$ 4.10%w/v TMM was shown good homogeneous echo texture and propagated speed as like the human Tissue. (3) $TiO_2$ type TMM was appeared lower brightness and higher penetration rate than C type TMM. Therefor, Breast TM phantom and target material TMM will be useful $TiO_2$ 4.10 %w/v TMM and C 2.09 %w/v TMM.

• Journal of Power System Engineering
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• v.13 no.5
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• pp.95-102
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• 2009

A steam generator (boiler) in thermal power plants, consisting of more than 30,000 parts and components, can lead to the plant shutdown with damage to even the small part of the components; esp., like weld failures on boiler tubes. Consequently it is greatly demanded to improve the quality of the weld on the boiler tube for the stable operation of the power plants. Because of the feature of the welding, which is done past by melting the work pieces and adding a filler material that cools to become a strong coalescence, there is a great possibility that weld failures take place. As a result, it is regulated to make a non-destructive testing, like radiography test, to detect defects and flaws in the weld. The current film radiography test provides a lower image quality exceeding 2.0% of a basic quality level for a penetrameter, it is very likely to fail to detect micro defect. As a result, the prevention for the boiler tube failure has not been made effectively. In this study, computed radiography technology has been applied as a digital radiography test to the boiler tube weld, and Se-75 radiation source was used to improve the image quality, instead of Ir-192 source. As a result of this study, it is proven to save the time and cost for test and to enhance the quality level of penetrameter penetrating image, which enables to upgrade the quality of radiography test to the boiler tube weld.

• Journal of Conservation Science
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• v.30 no.1
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• pp.81-93
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• 2014

As the Seated Iron Buddha Statues, Vairocana Buddha of Dopiansa Temple in Cheolwon, Nosana Buddha of Samhwasa Temple in Donghae and Sakyamuni of Mangisa Temple in Pyeongtaek were made during Unified Silla to Koryo Dynasty. These are damaged degradation which are crack, break-out, peel off and various pollutant. As a result of deterioration evaluation using radiography, crack, gap, break-out, pore space and restoration material are confirmed inside in the Buddha Statues. Based on iron strength, the Buddha Statues will be maintain current state as long as a high external impact is not applied. Also, iron core and nails used for fixing of internal and external framework were observed in the Buddha Statues. According to prominent line of surface, embossed inscription, hands cast separately and combined, the Buddha Statues were made by using division casting.

• Journal of the Korean Society of Radiology
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• v.17 no.1
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• pp.107-114
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• 2023

X-ray fluorescence analysis has been widely used in the field of science and industry because it gives information about elements and their concentrations without destruction of samples. To increase analysis accuracy of fluorescence generated by photons of the transmission-type X-ray tube for mixture and compound samples would be recommend to have strong energy near 10 keV and 20 keV simultaneously. Tungsten of 9.65 keV and molybdenum of 17.48 keV were considered as targets with dual deposition structure for obtaining two strong characteristic X-rays, and the transmission-type X-ray tube was analyzed using Geant4 Monte Carlo simulation. The W-Mo structure resulted in strong characteristic X-ray near 10 keV and 20 keV simultaneously. A structure with Mo-W multilayers of 5 ㎛ thick also gave optimal spectrum. Various material combination and thickness optimization for the dual-structured target can give X-ray spectrum with strong characteristic X-ray of specific energies.

• Radiation Oncology Journal
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• v.17 no.3
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• pp.230-237
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• 1999

Purpose : To elucidate the effects of pentoxifylline and diltiazem on the late response of the salivary glands of the rat after irradiation. Materials and Methods : Sixteen Sprague-Dawley rats were divided into 4 groups : (a) irradiation alone (b) irradiation with pentixifylline (PTX) (c) irradiation with diltiazem (DTZ) (d) irradiation with both PTX and DTZ. Irradiation was given in a single fraction of 16 Gy using 4 MV photon energy through an anterior port encompassing the left side of the salivary gland leaving the right side of salivary gland as a control. PTX, 20 mg/kg and/or DTZ, 50 mg/kg were infused intraperitoneally before irradiation, Two rats from each group were sacrificed on the 10th week and the rest was sacrificed on the 16th week after irradiation. Histopathologic examinations were undertaken for each section and the proportion of vacuolated cells out of the total number of cells under light microscopic fields was calculated. The statistical significance in the difference of the proportion of the vacuolated cells among the experimental groups was evaluated by a $x^2$-test. Results : Irradiated salivary glands of the 10th week group revealed markedly increased number of vacuolated cells compared to those of unirradiated control. The proportion of vacuolated cells was significantly reduced in both the PTX group (p value=0.001) and the combined PTX and DTX group compared to those of irradiation alone group. The DTZ alone group did not reveal the significant reduction of vacuolated cells compared to those of irradiation alone group (p value, >0.05). The 16th week groups revealed similar findings to those of the 10th week group, but the degree of chronic inflammatory cell infiltrates and interstitial fibrosis was increased and the number of acinar cells was reduced compared to those of the 10th week group. Conclusions : PTX significantly reduced the late radiation response of salivary glands, but DTZ did not reduce the same degree as PTX did. Taking the positive results of this study into consideration, it seems reasonable to apply PTX into the clinical trial for the head and neck irradiation to reduce the late radiation sequelae of salivary glands in the near future. At the same time the further experiment to clarify the subcellar mechni는 involved in PTX should be preceded.