• Journal of radiological science and technology
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• v.47 no.1
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• pp.1-6
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• 2024

In Recent years, there has been a noticeable increase in the global incidence of breast cancer, with approximately 2.3 million cases of female breast cancer reported worldwide in 2020. Numerous studies are currently underway to enhance the accuracy of breast cancer diagnosis through the development of digital mammography detectors. This study aims to create Monte Carlo simulation-based mammographic anti-scatter grids and investigate their utility in evaluating the performance of digital mammography detector. Two types of mammographic anti-scatter grids, MAM-CP and Senographe 600T HF, were created using Monte Carlo simulation software (MCNPX 2.7.0), with grid ratios of 3.7 : 1 and 5 : 1, respectively. The grid physical characteristics (sensitivity, exposure factor, contrast improvement ratio) were calculated based on the KS C IEC60627 in the simulations using two X-ray qualities, RQA-M2 (28 kVp) and MW4 (35 kVp). As the X-ray tube voltage increased from 28 kVp to 35 kVp, sensitivity and exposure factor exhibited a decreasing trend, while contrast improvement ratio demonstrated an increasing trend. With an increase in grid ratio from 3.7 : 1 to 5 : 1, all physical characteristics showed an upward trend. Our results were consistent with a previous study that conducted measurements of physical properties using a real phantom. However, the pattern of change in the contrast improvement ratio with X-ray tube voltage differed from the previous study.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2002.06a
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• pp.89-104
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• 2002

유전체연구사업단은 국내에서 발병 및 사망빈도가 가장 높은 위암과 간암의 퇴치를 목적으로 국가적 특목전략사업으로 연구를 추진하고 있다. 이와 별도로 보건복지부에서는 22개의 중요 질병별 유전체 연구센터를 전국적으로 추진하고 있다. 따라서, 연구가 성공적으로 진행되면 각 연구소에서 독자적으로 개발하여 제공하는 생명정보의 양은 거의 무한에 이를 것이다. 그러나 생명정보는 환자진료에 도움을 주기 위해서는 궁극적으로 임상정보와 함께 유기적으로 통합되어야 한다. 임상정보와의 통합을 위해서는 의료기관의 진료정보와 연구소의 생명정보가 연계되어 엄밀한 임상실험이 추가적으로 실시되어야 한다. 뿐만 아니라 생명정보학의 발전을 위해서는 연구대상의 임상정보가 공유되어야 한다. 유전체정보를 이용하는 생명정보학(Bioinformatics)은 각 국가마다 전략사업으로 간주하여 막대한 투자가 이루어지는 새로운 분야이다. 현재 선진국에서 개발 사용 중인 시스템의 연간 사용료가 고가이므로 국내 도입은 거의 불가능하거나 또는 매우 비효율적이다. 유전체 또는 생명정보의 임상활용 및 생명정보연구를 위한 임상정보 공유를 위해서는 우선 다음의 사항이 개발되어야 한다. 1) 다음과 같은 개별환자의 정보를 각 의료기관에서 제공 받아 저장 활용한다. - 진찰 및 임상소견, 수술기록, 경과기록, 검사결과 (임상병리, 해부병리, 방사선 등), - 영상정보 (X-ray, CT, MRI, 초음파, 전자현미경, 그래픽 등), - 환자개인기록(병력, 과거력, 가족력, 알러지 등), - 예방접종 기록 2) 각 연구소에서 첨단기술을 이용하여 개발되는 생명정보를 임상에 활용하기 위해서는 유전체연구센타와 병원간에 임상정보와 유전체 분석정보의 공유가 필수적으로 발생하게 됨으로, 유전체 정보와 임상정보의 통합은 미래 의료환경에 필수기능이 될 것이다. 3) 각 생명공학 연구소에서 사용하는 첨단 분석 장비와 생명공학 정보시스템의 자동 연계가 필요하다. 현재 국내에는 전국적인 초고속정보망이 가동되어 웹을 기반으로 하는 생명정보의 공유는 기술적으로 문제가 될 수 없으나 임상정보의 유전체연구에 그리고 유전체연구정보의 임상활용은 다양한 문제를 내포하고 있다. 이에 영상을 포함한 환자정보의 유전체연구센터와 병원정보시스템과의 효율적인 연계통합 운영을 위해 국내에서는 초기 도입단계에 있는 국제적인 보건의료정보의 표준인 Health Level 7 (textural information 공유), DICOM (image 및 wave 공유), 관련 ISO표준, WHO의 ICD9/10 (질병분류), LOINC (검사 및 관련용어), SNOMED International (의학용어) 등을 활용하여야 한다.

• Journal of the Korean Society of Radiology
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• v.13 no.5
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• pp.819-824
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• 2019

In this study, we proposed a method for identifying isotopes generated from high-energy proton $^{nat}Pb$(p,xn) nuclear reactions through the difference of gamma rays generated through nuclear reactions using different proton energies. The experiment was performed by using a high energy proton generated from a 100 MeV proton linear accelerator of the Korea Atomic Energy Research Institute. Gamma rays generated by various nuclides generated through proton nuclear reactions were measured using a gamma-ray spectroscopy system composed of HPGe detectors. Gamma-ray standard sources were used for accurate energy calibration and efficiency measurements of HPGe gamma-ray detectors. For the proposed method, 100 and 60 MeV proton energy beams were used for the same natural lead samples. This method was found to be very effective in identifying nuclides produced by comparing gamma rays generated from the same sample with each other. The results of this study are expected to be very effective in obtaining other proton nuclear reaction results in the future.

• Journal of the Korean Society of Radiology
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• v.13 no.5
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• pp.713-720
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• 2019

The purpose of this study was to propose a new measurement method for accurate measurement of vessel diameter in computed tomography angiography(CTA). CTA test was performed after non-ionic iodine contrast agent was flowed at a constant rate to self-maded perfusion phantom. After obtaining raw data, images were reconstructed with multi-planar reconstruction(MPR) and maximal intensity projection(MIP). Diameters of vascular models were measured for each technique. Relative and conventional measurements were then compared. The mean diameter of the vascular model was closer to the actual measurement when relative measurement was used compared to that when conventional measurement was used both in MPR and MIP. Relative measurements of MPR and MIP were closer to actual measurement than those of conventional measurement (34% VS, 24%, p<0.05). The relative measurement method proposed in this study was closer to the actual measurement than the conventional measurement method. However, both test methods were still larger than actual results. Therefore, further study of relative measurement method is needed using this study as basic data.

• Journal of the Korean Society of Radiology
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• v.16 no.5
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• pp.545-551
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• 2022

This study analyzed the correlation between stress measurements calculated through HRV signals and thyroid function test items. 181 healthy adults without disease who visited Clinic K were the subjects of this study. Stress resistance (SR) and stress index (SI) were calculated using the acquired HRV signal, and TSH, Free T4, and T3 were used as thyroid function test items. For the measured values, the relationship between each item was statistically analyzed through Pearson correlation analysis. From the results, it was confirmed that Free T4 and SR had a positive correlation (r=0.18) and a negative correlation with SI (r=-0.16). Through this, it was confirmed that there is a significant relationship between thyroid function and HRV signal.

• Journal of the Korean Society of Radiology
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• v.12 no.1
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• pp.93-100
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• 2018

The fractional anisotropy value of the brain white matter region was analyzed by Tract-Based Spatial Statics(TBSS) method after acquiring the diffusion tensor image to identify the presence or absence of brain white matter damage to smoking in male. As a result, smokers showed lower fractional anisotropy than non-smokers in all areas but fractional anisotropy values were not statistically significant. the fractional anisotropy value, on the other hand, was statistically significant only for the right choroid plexus. In other words smoking, although, does not significantly affect the micro structural changes of brain white matter, it affects the choroid plexus area.

• Journal of Digestive Cancer Research
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• v.4 no.1
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• pp.21-28
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• 2016

Hepatocellular carcinoma (HCC) is rather unique. Most of HCC patients have underlying chronic liver diseases with or without cirrhosis and the prognosis of HCC depends on the liver function, as well as the tumor extent. Non-invasive diagnosis of HCC can be made with certain risk factors and specific imaging findings (e.g. hypervascularity). Patients with HCC can receive surgical resection, radiotherapy, and systemic chemotherapy as other solid malignancies. HCC has more treatment options such as liver transplantation, transarterial chemoembolization (TACE) and radiofrequency ablation (RFA). A variety of practice guidelines for HCC has been published by many academic societies. Different healthcare systems and availability of resources also affect the practice guidelines; therefore, practice guidelines have similarities and dissimilarities. Herein, we review the current status of practice guidelines for HCC and future perspectives for the improvement of guidelines are also discussed.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.761-766
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• 2023

In this paper, TI was measured to classify the presence or absence of mild left ventricular diastolic dysfunction. Of the total 306 data, 206 were used as training data and 100 were used as test data, and the machine learning models used for classification used SVM and KNN. As a result, it was confirmed that SVM showed relatively higher accuracy than KNN and was more useful in diagnosing the presence of left ventricular diastolic dysfunction. In future research, it is expected that classification performance can be further improved by adding various indicators that evaluate not only TI but also cardiac function and securing more data. Furthermore, it is expected to be used as basic data to predict and classify other diseases and solve the problem of insufficient medical manpower compared to the increasing number of tests.

• Journal of the Korean Society of Radiology
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• v.16 no.7
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• pp.975-984
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• 2022

Since a linear transducer has an area of interest equal to the length of the transducer, the area of interest can be expanded using the virtual convex function installed in the device.However, it was thought that the change in the direction of the ultrasonic sound velocity according to the change in the visual area of interest would affect the image quality, so this was objectively confirmed. For this study, image evaluation and SNR·CNR of the phantom for ultrasound quality control were measured. As a result, in the phantom image evaluation, both images were able to identify structures in functional resolution, grayscale, and dynamic range. However, it was confirmed that the standard image was excellent in the reproducibility of the size and shape of the structure. As a result of SNR·CNR evaluation, SNR·CNR of most trapezoidal images was low, except for structures at specific locations. In addition, through the statistical analysis graph, it was further confirmed that the SNR and CNR for each depth decreased as the size of the cystic structure decreased. Through this study, it was confirmed that the use of the function has the advantage of providing a wide visual area of interest, but it has an effect on the image quality. Therefore, when using the virtual convex function, it is judged that the examiner should use it in an appropriate situation and conduct various studies to acquire high-quality images and to improve the understanding and proficiency of the equipment.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.605-611
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• 2019

The purpose of this study is to manufacture a multi-function device (MFD) which can be applied to various types of weight-bearing view of the lower leg, and to compare the results with the images from the existing weight-bearing platforms (WBPs), thereby suggesting a clinical utilization. The MFD was manufactured, by considering the minimum adjustable heights of the platform for weight-bearing foot/ankle, platform for hindfoot alignment view, and X-ray tube of the X-ray device. A foot/ankle phantom was used to take the images of weight-bearing lateral foot in MFD and WBPs to compare the resolutions of the X-ray images using a quick modulation transfer function (MTF) program. Between both the images taken from the MFD and WBPs, there was no statistically significant difference found in the mean cycles per pixel (C/P) and the lines per image height (LPH) of the 50%-Contrast Spatial Frequency (MTF50), and 10-90% of Maximum Energy Rise Distance (10-90%), where p>0.05. The MFD is suggested for its clinical trial as a useful positioning device that can secure the patient's safety and manifoldly perform various inspections. Also, the recommendation of the positioning device as a policy can activate dedicated manufacturers, while also improving the quality of medical services.