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Effect of Water Extracts from Phellinus linteus on Lipid Composition and Antioxidative System in Rats Fed High Fat High Cholesterol Diet (상황버섯(Phellinus linteus) 추출물이 고지방.고콜레스테롤 식이 흰쥐의 지질조성 및 항산화계에 미치는 영향)

  • Song, Won-Young;Sung, Byoung-Hun;Kang, Sin-Kwon;Choi, Jeong-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.1
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    • pp.71-77
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    • 2010
  • The purpose of the present study was to examine the effect of water extracts from Phellinus linteus on lipid composition and antioxidative system in rats fed high fat high cholesterol diet. Rats were divided into four experimental groups which are composed of normal diet group, high fat high cholesterol diet group, high fat high cholesterol diet with 50 mg/kg b.w water extracts from Phellinus linteus supplemented group (PA group), high fat high cholesterol diet with 100 mg/kg b.w water extracts from Phellinus linteus supplemented group (PB group). The serum TG and cholesterol contents of the water extracts from Phellinus linteus supplemented groups (PA and PB groups) were decreased compared to the high fat high cholesterol diet group. The serum HDL-cholesterol contents of the water extracts from Phellinus linteus supplemented groups were increased compared to the high fat high cholesterol diet group. The serum LDL-cholesterol and AI of the water extracts from Phellinus linteus supplemented groups were significantly decreased compared to the high fat high cholesterol diet group. Supplementation of water extracts from Phellinus linteus groups (PA and PB groups) resulted in increased activities of superoxide dismutase. Hepatic glutathione peroxidase (GSH-px) were increased compared to the high fat high cholesterol diet group. TBARS values in liver and plasma were reduced in water extracts from Phellinus linteus supplemented groups. These result suggest that supplementation of water extracts from Phellinus linteus may have a pronounced impact on lipid composition and antioxidative system in the rats fed high fat high cholesterol diet.

Effect of Young Barley Leaf on Lipid Contents and Hepatic Lipid-Regulating Enzyme Activities in Mice Fed High-Fat Diet (보리순이 고지방을 급여한 마우스의 지질 함량과 간조직의 지질대사 관련 효소활성에 미치는 영향)

  • Yang, Eun-Ju;Cho, Young-Sook;Choi, Myung-Sook;Woo, Myoung-Nam;Kim, Myung-Joo;Shon, Mi-Yae;Lee, Mi-Kyung
    • Journal of Nutrition and Health
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    • v.42 no.1
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    • pp.14-22
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    • 2009
  • This study was conducted to investigate the effects of powdered young barley leaf and its water extract on body weight and lipid metabolism in high-fat fed mice. Male mice were divided into normal group, high-fat (HF) group, high-fat group supplemented with powdered young barley leaf (HF-YBL) and high-fat group supplemented with water extract of the powdered young barley leaf (HF-WYBL). The powdered young barley leaf or its water extract was added to a standard diet based on 1% dried young barley leaf (1 g YBL/100 diet and 0.28 g WYBL/100 g diet) for 8 weeks. Supplementation of YBL and WYBL significantly reduced body weight and epididymal adipose tissue weight in high-fat fed mice. Food intake and daily energy intake were significantly lower in the YBL group than in the HF group. After 8 weeks, plasma triglyceride and cholesterol concentrations were significantly higher in the HF group than in the Normal group; however, both YBL and WYBL significantly lowered those of the high-fat fed mice. The ratio of HDL-cholesterol/total cholesterol of the YBL and WYBL groups were significantly elevated compared to that of HF group. Both YBL and WYBL significantly increased fecal excretion of triglyceride in high-fat fed mice, whereas they did not affect fecal cholesterol concentration. The triglyceride levels of liver, adipose tissue and heart were significantly lower in the YBL and WYBL groups than in the HF group. Supplementation of WYBL also lowered the kidney triglyceride and heart cholesterol concentrations compared to those of HF group. Hepatic lipid regulating enzyme activities, fatty acid synthase, HMG-CoA reductase and acyl-coenzyme A: cholesterol acyltransferase, were significantly lower in the YBL and WYBL groups than in the HF group. Accordingly, these results suggest that YBL and WYBL improve plasma and organ lipid levels partly by increasing fecal lipid excretion and inhibiting fatty acid and cholesterol biosynthesis in the liver.

Effects of Baked Garlic Powder on Lipid Metabolism in Rats Fed a High-Fat/High-Cholesterol Diet (구운 마늘 분말이 고지방-고콜레스테롤 식이를 급여한 흰쥐의 체내 지질대사에 미치는 효과)

  • Lee, Oun-Ju;Lee, Jae-Joon;Lee, Myung-Yul;Lee, Hyun-Joo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.1
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    • pp.49-56
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    • 2012
  • This study examined the effects of baked garlic powder on the lipid metabolism in rats fed a high-fat/highcholesterol diet for 4 weeks to induce hyperlipidemia. Male Sprague-Dawley rats were assigned to four groups according to the dietary fat, cholesterol and baked garlic powder levels. The experimental groups were normal diet group (N), a high-fat/high-cholesterol diet group (C), a high-fat/high-cholesterol diet with 1.5% baked garlic powder group (GPL) and a high-fat/high-cholesterol diet with 3% baked garlic powder group (GPH). The body weight gain, food intake and food efficiency ratio were similar in the experimental groups. The epididymal adipose tissues weight of the C group was higher than that of the N group, whereas those of the groups fed baked garlic powder were decreased gradually. The ALT and ALP activities were similar in the C groups, but the serum AST and LDH activities elevated by a high-fat/high-cholesterol diet were decreased significantly by feeding a 3% baked garlic powder diet. The serum triglyceride, total cholesterol and LDL-cholesterol levels as well as the atherogenic index and cardiac risk factor tended to decrease in the groups fed baked garlic powder than the C group, whereas the serum HDL-cholesterol level was lower in the C group and remarkably in groups fed baked garlic powder than the control group. The total cholesterol level in the liver and mesenteric adipose tissue and the triglyceride level in epididymal tissue were lower in the groups fed baked garlic powder than the C group. These results suggest that baked garlic powder reduces the serum lipid components and improves the lipid metabolism in hyperlipidemic rats induced with a high-fat/high-cholesterol diet.

Effects of Raising System on the Reproductive and Weaning Performances in Replacing Gilts (후보모돈의 실내.외 사육방식이 번식 및 이유성적에 미치는 영향)

  • Kim, G.W.;Ok, Y.S.;Kim, S.E.
    • Journal of Animal Environmental Science
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    • v.15 no.1
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    • pp.1-8
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    • 2009
  • This study was conducted to analyze the effects of sow breeding environment on the reproduction in the first litter in a large-sized hog farm, located in Dangjin-gun, Chungnam from July 1st, 2007 to June 30th, 2008 and provide basic information to improve the sow productivity in a family farming sows. The results obtained were as follows; 1. The gestation periods were proved to be similar without significant differences between indoor and outdoor breeding grounds, The average of farrowing rate was 91.91%, and 92.54% farrowing rate of out-door ground breeding sows was slightly greater than 91.57% of group-housed sows, but there was no significance between two groups. 2. The average of total litter size and the number of born alive per litter were 9.81 and 9.02, respectively. The number of total number was 0.98 and the number of born alive per litter was 1.18 in the outdoor-ground breeding sows, which was significantly greater than group-housed sows(p<0.001). 3. The number(rate) of piglets stillborn was 0.22(2.10%) from the outdoor-ground breeding sows was significantly greater, compared with 0.33(3.53%) from group-housed sows(p<0.01). The number of piglets culled was 0.23(2.27%) and 0.26(2.77%), in the out-door ground breeding sows and in group-housed sows, respectively and it was not significantly similar between two groups. And, the number of mummies was 0.21(2.1%) and 0.28(2.29%), in the out-door ground breeding sows and in group-housed sows, respectively, which showed no significance. 4. The weaning number in the playground breeding sows was 9.48 and it was significantly greater than that in the group-housed sows(p<0.001). The average of weaned age was observed to be 22.91 days. The weaned age in the out-door ground breeding sows was 22.39 days, and it was significantly smaller than that in group-housed sows(p<0.001). The breeding rate for the weaning of pigs was satisfactory as 96.82%, but there was no significant difference between two groups.

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Anti-Obesity and Hypolipidemic Activity of Taro Powder in Mice Fed with High Fat and Cholesterol Diets (고지방 식이를 섭취한 마우스에서 토란분말의 비만억제 및 지질저하 효과)

  • Moon, Ji-Hye;Sung, Jee-Hye;Choi, In-Wook;Kim, Yoon-Sook
    • Korean Journal of Food Science and Technology
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    • v.42 no.5
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    • pp.620-626
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    • 2010
  • This study was conducted to investigate the effects of taro powder on body weight and lipid metabolism in high fat and cholesterol fed mice. C57BL6 mice were divided into four groups; normal (normal) diet group, a high fat and cholesterol (HF) diet group, and high fat and cholesterol diet groups with 20% taro powder (HF-taro 20%) and 30% taro powder (HF-taro 30%). After 8 weeks, body weight in the HF group increased to 175% of the normal group, while those of HF-taro 20% and HF-taro 30% group decreased by 12.5 and 14% compared to the HF group. The HF-taro 20% and HF-taro 30% groups had significantly reduced epididymal adipose tissue weight. Plasma triglyceride, total cholesterol, and LDL-cholesterol concentrations were significantly higher in the HF group than those in the normal group, while their amounts were significantly diminished in the HF- taro 20% and HF- taro 30% groups. Furthermore, the leptin and insulin concentrations in blood plasma decreased significantly in the HF-taro 20% and HF-taro 30% groups. Accumulation of triglycerides and cholesterol in the liver was significantly inhibited in the HF- taro 20% and HF-taro 30% groups through liver weights, a blood analysis, and histological findings. These results suggest that taro powder may be an effective material for anti-obesity by reducing plasma triglyceride and cholesterol levels.

Hypolipidemic Effect of Onion Peel Extract in Rats Exposed to Cigarette Smoke Extract with a High-Fat Diet (고지방식이를 섭취한 흡연 흰쥐모델에서 양파껍질 추출물의 혈액지질 대사 개선 효과)

  • Kim, Juyeon;Noh, Sang Kyu
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.2
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    • pp.161-166
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    • 2016
  • This study was designed to investigate whether or not onion peel extract can lower blood lipid levels in rats exposed to cigarette smoke (CS) extract with a high-fat diet. Initially, male Sprague-Dawley rats were housed individually in a stainless steel, wire-bottomed cage with free access to AIN-93G diet. Rats were weight-matched and assigned to the following five groups: 1) control rats (CT) fed standard AIN-93G diet alone, 2) control rats exposed to CS extract (CT+CS), 3) high-fat group (HF) fed standard AIN-93 diet supplemented with 3% lard and 0.2% cholesterol, 4) high-fat group exposed to CS extract (HF+CS) fed standard AIN-93 diet supplemented with 3% lard and 0.2% cholesterol plus CS extract, and 5) high-fat plus onion peel (OP) extract group exposed to CS extract (HF+CS+OP) fed standard AIN-93 diet supplemented with 3% lard, 0.2% cholesterol, and onion peel extract (20 mg/17 g diet) plus CS extract. Using this feeding protocol, all animals completely consumed their respective diets throughout the 6 week duration. Blood was collected via the orbital sinus at weeks 0, 3, and 6, following overnight food deprivation. OP extract feeding resulted in significant reductions in blood triglyceride, total cholesterol, and non-HDL-cholesterol. Further, serum activities of aspartate transaminase and alanine transaminase were significantly reduced by OP extract at 6 weeks. These results provide clear evidence that onion peel extract has a profound inhibitory effect on blood lipids in rats exposed to CS extract. These findings suggest that OP extract can be used as an effective means in alleviating the serum lipid concentration after CS exposure.

A Study on the Hangul Banggakbon Novels in the Harvard-Yenching Library (미국 하버드옌칭도서관 소장 한글 방각본 소설 연구)

  • Lee, Hye-Eun;Yoo, Choon-Dong
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.24 no.2
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    • pp.113-128
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    • 2013
  • This study targets ten titles of Hangul banggakbon novels in the Harvard Yenching Library to examine the bibliography, system, and characteristics. Among the ten titles, gyeongpanbon Guunmong, Leehaeryongjeon, Chunhyangjeon, Janggyeongjeon, two titles of Sodaeseongjeon, Honggildongjeon, anseongpanbon Yangpungunjeon, and two titles of wanpanbon Hwaryongdo have been found in Korea, too. However, gyeongpanbon Chunhyangjeon, 30 jangbon of Hyogyosingan(孝橋新刊), and wanpanbon Hwaryongdo seogyeseopobon are the ones that can be hardly found in Korea, and the library has possessed it there so far. With the two titles of Hangul banggakbon novels, it will be needed to reexamine the aspects of publishing Hangul banggakbon novels afterwards. Hangul banggakbon novels that Harvard-Yenching Library has now are mostly the ones that can be easily found in Korea, too. It is because the data started to be collected from the 1950's. In comparison with the materials in England, Russia, or Japan in the early 1890's, there are no rare books that cannot be found in Korea. The reason for this may be found from this.

Study on Police-led National Response against CBRN Terror by Strengthening the Standing Cooperation System of the Interagencies (다부처 상설 협력체계 구축을 통한 경찰주도 국가 화생방 테러대응 발전방안)

  • Cha, Jang-Hyeon;Kang, Taeho;Kim, Daesoo;Lee, Hochan
    • Korean Security Journal
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    • no.59
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    • pp.217-242
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    • 2019
  • Nowadays, Terrorism has become bloodier. Unlike the past, the recent terrorism has been indiscriminate in the purpose of mass- killing. Given this aspect, the threat of a CBRN attack is the biggest one to modern society. Notably, the possibility of terrorist attacks in Korea by international terrorist groups such as ISIL is higher than ever in consideration of its allusion; crusades and the devil's allied forces. To overcome these circumstances, various measures have been taken for counter terrorism at the state level including anti-terrorist legislation. Under the anti-terrorist act, police have to lead relevant inter agencies when it comes to the CBRN terror. At first glance, current countermeasures would work well. However, in order to respond quickly, the standing cooperations system of related departments need to be set up. In this sense, this article proposed a coagulatory body that could not only consider institutional-oriented organizational restructuring and response but also integrate and operate functions of various specialized institutions. It also stressed that the council should move toward a consultative body of information gathering, distribution and working- level consultation. With this cooperation system, counter-terrorism agencies can respond rapidly, stop wasting their effort and assets by about 30%. Also, they could design the atypical aspect of terrorism into standardized.

Anteroinferior Capsulolabral Complex Repair Using Antegrade Suture Passer - Technical Note - (Antegrade Suture Passer를 이용한 전하방 관절낭-관절와순 복합체의 복원술 - 수술 술기 -)

  • Seo, Hyuk-Jun;Cho, Chul-Hyun;Lee, Si-Wook
    • Journal of the Korean Arthroscopy Society
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    • v.17 no.1
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    • pp.95-99
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    • 2013
  • We introduce arthroscopic Bankart repair technique using antegrade suture passer that can effectively restore detached anteroinferior capsulolabral complex for shoulder anterior instability. After diagnostic arthroscopy is performed using posterior, anteroinferior and anterosuperior portals, we confirm Bankart lesion and perform debridement and decortications of anteroinferior glenoid edge and neck. Suture anchor is inserted through anteroinferior portal at 2 mm medial side of glenoid edge (4:30 direction). Scorpion$^{TM}$ loaded suture is directly advanced to detached and retracted anteroinferior capsulolabral complex and the suture is passed at 10~15 mm medial side of detached anteroinferior capsulolabral complex (5:30 direction). The suture is retrieved by Scorpion's hook and then is tied using samsung medical center (SMC) sliding knot technique. Then suture anchors are serially inserted (2:30, 3:30) and capsulolabral complex repair is performed using suture hook and suttle-relay technique. This technique that can obtain anatomical restoration of anteroinferior glenohumeral ligament with proper tension is useful technique to reduce postoperative recurrence and makes it possible for less experienced surgeons.

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A Study on the Correlation between the Volume of Indoor Space and the Measured Concentration of Indoor Radon (실내 체적과 라돈 농도와의 상관관계 연구)

  • Kang, Sung-A;Han, Dong-Hyun;Kim, Chong-Yeal
    • Journal of Radiation Protection and Research
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    • v.32 no.3
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    • pp.97-104
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    • 2007
  • The corelation between the indoor volume and the measured radon concentration has been analyzed by comparing the radon concentration and the indoor volume of apartment rooms in Jeonju City. We also measured the annual exposure dose based on the variation in indoor radon concentration over time. To do this, we took 8 larger rooms and 8 smaller rooms of apartment, respectively, as a sample. The average volume of the larger rooms and that of the smaller rooms were $31.59\;m^3$ and $16.82\;m^3$, respectively. The average radon concentration of the larger rooms and that of the smaller rooms turned out to be $71.73\;Bq/m^3$ and $108.51\;Eq/m^3$, respectively. indicating that indoor volume is in inverse proportion to the radon concentration, i.e., the bigger the ratio of the surface area/volume, the higher the indoor radon concentration. From the measurement of the variation in indoor radon concentration over time fur a single day, the average intraday radon concentration variation was found to be about $46.8\;Bq/m^3$. The highest level of concentration ($114.5\;Bq/m^3$) was measured between 8 and 10 AM and the lowest level of concentration ($67.7\;Bq/m^3$) between 2 and 4 PM. The annual exposure dose turned out to be in the range of 0.3 mSv/yr to 2.16 mSv/yr, showing that the dose in some apartments exceeded 1.3 mSv/yr, the numerical value presented by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR).