• Title/Summary/Keyword: 발암성

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Use of $^{18}F$-FDG PET/CT in Second Primary Cancer (이차성 원발암에서의 $^{18}F$-FDG PET/CT의 이용)

  • Choi, Joon-Young;Kim, Byung-Tae
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.3
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    • pp.185-193
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    • 2007

  • This review focuses on the use of $^{18}F-FDG$ PET/CT to evaluate second primary cancers. The emergence of a second primary cancer is an important prognostic factor in cancer patients. The early detection of a second primary cancer and the appropriate treatment are essential for reducing the morbidity and mortality associated with these tumors. Integrated $^{18}F-FDG$ PET/CT, which can provide both the metabolic and anatomic information of a cancer, has been shown to have a better accuracy in oncology than either CT or conventional PET. The whole body coverage and high sensitivity of $^{18}F-FDG$ PET/CT along with its ability to provide both metabolic and anatomic information of a cancer make it suitable for evaluating a second primary cancer in oncology. Whole body $^{18}F-FDG$ PET/CT is useful for screening second primary cancers with a high sensitivity and good positive predictive value. In order to rule out the presence of a second primary cancer or an unexpected metastasis, further diagnostic work-up is essential when abnormal findings indicative of a second primary cancer are found on the PET/CT images. PET/CT is better in detecting a second primary tumor than conventional PET.

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Temporal and Spacial Variation of PAHs and Their Dry Deposition in Seoul (서울 도심 및 배경지역에서 PAHs의 시ㆍ공간적 분포와 건식 침적 특성)

  • 이지이;김용표;이승묵
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2003.11a
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    • pp.339-340
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    • 2003

  • 최근 들어서 환경유해물질이 인체에 미치는 영향에 대한 관심이 커지고 있다. 특히 환경 중에 존재하는 발암성 물질에 대한 연구가 활발히 진행되면서 이들 물질이 인체에 미치는 위해성이 밝혀지고 있다. 다환방향족탄화수소(Polycyclic Aromatic Hydrocarbons, PAHs) 는 환경에 존재하는 중요한 발암물질이자 돌연변이 유도체이다. PAHs는 화석연료의 불완전 연소 등에 의해 발생되고, 대표적인 오염원으로는 석탄 연소, 자동차, 가정 난방 등이 있다. (중략)

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Effect of Several Endocrine Disrupting Compound on Mammary Gland Carcinogenesis in c-Ha-ras-trasgenic Rats

  • Han, Bum-Sup
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2001.09a
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    • pp.13-15
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    • 2001

  • 발암성시험연구에 사용되고 있는 형질전환 동물들은 랫드와 마우스 등이 있는데, 그 중 c-Ha-ras proto-oncogene 마우스 (ras H2 mice), v-Ha-ras 형질전환 마우스 (Tg.AC mice), pim-1 형질전환 마우스 및 p53 knockout 마우스 등이 발암유발물질에 감수성이 높아 현재 중기발암성시험에 이용되고 있다. (중략)

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