• Title/Summary/Keyword: 발생빈도값

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Postoperative Complications after Preoperative Chemoradiotherapy Combined with Hyperthermia in Locally Advanced Rectal Cancer (국소 진행성 직장암의 수술전 동시 화학방사선치료와 온열치료병합시 수술후 부작용)

  • Yea, Ji Woon
    • Progress in Medical Physics
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    • v.25 no.2
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    • pp.89-94
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    • 2014
  • We investigated whether regional hyperthermia (HT) increased post-surgical complications in patients with locally advanced rectal cancer treated with preoperative concurrent chemoradiotherapy (CCRT). Between 1996 and 2007, 205 patients treated with preoperative CCRT and curative surgery were evaluable for the analysis of acute and late toxicities. A total dose of 39.6 Gy or 45 Gy was delivered concurrently with one or two cycles of chemotherapy (5-fluorouracil, leucovorin). Eighty-eight patients received regional HT twice a week using an 8-MHz radiofrequency capacitive heating device. Surgery was performed 4~6 weeks after the completion of preoperative CCRT. The median age was 59 years (range, 18~83) and the median follow-up period was 61months (range, 2~191). The 5-year overall survival and complication-free survival rate of all patients was 77.4% and 73.7%, respectively. Early leakage, delayed leakage, anastomotic stricture, fistula, and small bowel obstruction occurred in 1.0%, 2.9%, 1.5%, 5.9%, and 17.1%, respectively. HT did not increase all kinds of complications. The 5-year complication-free survival rate was 71.8% in the non-HT group and 76.3% in the HT group (p=0.293). Regional HT did not increase postoperative complications in patients with locally advanced rectal cancer treated with preoperative CCRT followed by curative surgery.

A Correlation Study of Surveillance Data and ATP Bioluminescence Assay for Verification of Hygienic Status in Major Hotels in Seoul (서울 시내 주요 호텔의 위생실태 조사와 ATP 결과의 상관 분석 연구)

  • Kim, Bo-Yeon;Song, Ha-Young;Park, In-Sook;Kim, Yong-Su;Lee, Yu-Si;Ha, Sang-Do
    • Journal of Food Hygiene and Safety
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    • v.24 no.3
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    • pp.277-284
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    • 2009
  • Currently food-borne disease is being increased at outdoor food services including hotels and restaurants. Speedy and convenient practical monitoring techniques to determine hygienic conditions are needed. This study was designed to verify correlation of direct ATP (Adenosine Tri-Phosphate) examination method using ATP bioluminescence and surveillance with check-list by inspector. Hygienic status of personal hygiene (hands), kitchen utensils (knives, chopping boards, kitchen towels, cap openers, food storage containers, and blade of slice machines), facilities and equipments (refrigerator handles, worktables, and sinks) in five major hotels in Seoul were examined. The result of personal hygiene of hotels was relatively better than other inspection items (46.6 points in personal hygiene, 40.2 points in kitchen utensils, 40.3 points in facilities & equipments). In ATP inspection, kitchen utensils and facilities & equipments were relatively clean comparing with personal hands data ($40.8{\pm}6.77\;RLU/cm^2$). After correlation analysis of surveillance in hygienic status points and ATP value, all results showed negative and high correlation. The surveillance data and ATP results investigating personal hygiene, kitchen utensils and facilities & equipments were highly correlated. The ATP examination method which shows real-time identification could be considered as an appropriate method to alternate current check-list dependent safety management in food services including hotels.

Water Soluble Ionic Components in Precipitation at ChungNam West-Coast Area (충남 서해안지역 강수 중 수용성 이온 성분의 변화특성)

  • 정진도;이천호
    • Journal of Environmental Science International
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    • v.12 no.12
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    • pp.1285-1292
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    • 2003
  • This study was compared each ingredient's local/seasonal change characteristics by analyzing anions and cations, watersoluble ionic components, from the precipitation of Dangjin and Anmyeon-do areas. The samples were collected for 8 months from both spots between the period of April 1, 2002 to November 31, 2002. The precipitation samples were collected continuously through the entire duration of precipitation by using the wet-only automatic samplers. When rain continues to fall over 24 hours or occasionally, we considered those collected from 9 o'clock in the morning for 24 hours as the day's samples. As a method to verify for the reliability of the analyzed data is concerned, we use the ion balance method and the electricity conductance method, was used widely as a way of watching the atmosphere by the WMO(World Meteorological Organization)/GAW (Global Atmosphere Watch). Also, Dangjin and Anmyun-do area confirmed that contains artificial pollutants by analysis of ion concentration data.

Experimental Study on Gasification Characteristic by Using Liquefied Gas Vaporizer with Various Shape (다양한 형상을 갖는 액화가스용 기화기의 기화특성에 관한 실험적 연구)

  • Lee, Y.H.;Eldwin, D;Chung, H.S.;Jeong, H.M.
    • Journal of Power System Engineering
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    • v.11 no.2
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    • pp.5-11
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    • 2007
  • 액화천연가스(LNG : Liquified Natural Gas)는 연료로 사용하기 위하여 기화하는 과정을 거치게 되는데 기화하는 방식에는 해수에 의한 기화와 공기에 의한 기화의 두 가지 방식으로 나뉘게 된다. 해수에 의한 기화는 LNG 인수기지에서 대량의 LNG를 NG로 기화하기 위하여 사용하며, 공기에 의한 기화는 LNG 위성기지에서 사용처에 적합한 온도를 얻기 위해서 일반적으로 많이 사용하고 있는 공기식 기화기를 이용하여 기화를 하는 방식을 취하고 있다. LNG가 NG로 기화하는 과정에서 1kg당 200kcal의 냉열을 외부로 방출하고 있으며, 이러한 냉열의 방출로 인하여 공기식 기화기의 표면에 결빙현상을 발생시킨다. 또한 현재 사용하고 있는 기화기는 $2{\sim}3$개의 기화기를 연결하여 사용하고 있어 그 비용의 손실이 크다고 할 수 있다. 그리하여 본 연구는 최근 사용빈도가 증가하고 있는 공기식 기화기에 관한 것으로 작동유체는 실제 LNG와 특성이 비슷한 초저온 액화가스인 $LN_2$를 사용하였다. 이번 연구에 사용된 변수는 다음과 같다. 첫째, 각각의 기화기의 길이를 4000mm, 6000mm, 8000mm으로 하였고 핀의 type을 finless, 4fin, 8fin으로 하여 적용하였다. 두 번째는 봄, 여름, 가을, 겨울철에 따른 기화기의 성능을 알고자 각각의 계절별 온도와 습도를 적용하였다. 마지막으로 계절별 풍속과 실험을 하는 시간 동안의 유량을 알고자 압력을 1 bar로 적용하였다. 그리하여 이번 연구의 목적으로는 각각의 변수를 통하여 실험을 진행 한 후 vaporizer type과 길이에 대한 최적의 성능을 가지는 기화기에 대한 자료를 제시하고자 한다.기성분은 균주에 따른 약간의 차이가 있었으나 경향은 비슷하게 나타났다. 이상의 결과 알코올 발효 균주에 따른 참다래 와인의 이화학적 품질특성에는 큰 차이가 없었으나 고급알코올함량을 비교하였을 때 Sacch. cerevisiae Wine 3이 와인제조에 가장 적합한 것으로 평가되었다.장 낮은 값을 나타내었으며, 홍국의 함유량이 증가할수록 유의적으로 증가하였다. b값은 CSB가 가장 낮은 값을 나타내었으며, 홍국의 함유량이 증가할수록 유의적으로 증가하였다. 물성측정 결과 경도와 응집성은 각 시료들 간의 유의적인 차이가 나타나지 않았다. 탄력성과 부서짐성은 CSB가 가장 낮았으며, 홍국의 함유량이 증가할수록 증가하였다. 점착성은 SDB1이 가장 낮았으며, 홍국의 함유량이 증가할수록 증가하였다. 관능검사 결과 기공의 균일성은 SDB1이 가장 균일한 것으로 나타났으며, 색은 홍국의 함유량이 증가할수록 높게 나타났다. 경도, 탄력성, 단맛 및 신맛 등은 홍국 함유량이 증가할수록 증가하는 것으로 나타났다. 이취는 SDB1이 가장 적게 나는 것으로 나타났으며, 전반적인 기호도는 SDB1이 가장 높았다. 따라서 홍국을 10% 첨가한 sourdough starter를 3일 동안 발효한 후 반죽에 첨가하여 sourdough bread를 제조할 때 품질이 가장 우수한 제품을 얻을 수 있었다.생수와 여러 물질의 혼합용액의 온도가 장에 끼치는 자극에 차이가 있지 않나 추측되며 이에 관한 추후 연구가 요망된다. 총대장통과시간의 단축은 결장 분절 모두에서 줄어들어 나타났으나 좌측결장 통과시간의 감소 및 이로 인한 이 부위의 통과시간 비율의 저하가 가장 주요하였다. 이러한 결과는 차가운 생수 섭취가 주로 결장 근위부를 자극하는 효과를 발휘하는 것이 아닌가

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Evaluation of Typhoon Hazard Factors using the EST Approach (EST 기법에 의한 태풍의 재해위험인자 평가)

  • Lee, Soon-Cheol;Kim, Jin-Kyoo;Oh, Kyoung-Doo;Jun, Byong-Ho;Hong, Il-Pyo
    • Journal of Korea Water Resources Association
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    • v.38 no.10 s.159
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    • pp.825-839
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    • 2005
  • Application of the EST approach for the simulation of the risk-based typhoon hazard potential is described in this paper. For six selected cities In the Korean peninsula, EST simulations for one hundred years were performed one hundred times using historical typhoon data as a training data set. The analytical results of EST simulations were then post-processed to estimate the means, standard deviations, and ranges of variation for the maximum wind velocities and the daily rainfalls. From the comparison of the averages of the wind velocities for the 100 year recurrence interval typhoons, the wind hazard potential of them was revealed to be highest for Mokpo among the six cities, followed by Busan, Cheju, Inchun, Taegu, and Seoul in descending order For the flood hazard potential associated with a typhoon, Busan was ranked to be the highest hazard potential area, followed by Mokpo, Cheju, Seoul, Inckun, and Taegu. In terms of the overall typhoon hazard potential, cities in the southern coastal regions were identified as being exposed to the most severe typhoon hazard.

Latent mobility pattern analysis of bus passengers with LDA (LDA 기법을 이용한 버스 승객의 잠재적 이동패턴 분석)

  • Cho, Ah;Lee, Kyung Hee;Cho, Wan Sup
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.5
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    • pp.1061-1069
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    • 2015
  • Recently, transportation big data generated in the transportation sector has been widely used in the transportation policies making and efficient system management. Bus passengers' mobility patterns are useful insight for transportation policy maker to optimize bus lines and time intervals in a city. We propose a new methodology to discover mobility patterns by using transportation card data. We first estimate the bus stations where the passengers get-off because the transportation card data don't have the get-off information in most cities. We then applies LDA (Latent Dirichlet Allocation), the most representative topic modeling technique, to discover mobility patterns of bus passengers in Cheong-Ju city. To understand discovered patterns, we construct a data warehouse and perform multi-dimensional analysis by bus-route, region, time-period, and the mobility patterns (get-on/get-off station). In the case of Cheong Ju, we discovered mobility pattern 1 from suburban area to Cheong-Ju terminal, mobility pattern 2 from residential area to commercial area, mobility pattern 3 from school areas to commercial area.

Evaluation of Harbour Tranquility Improvement in Pohang New Port by Detached Breakwater (포항신항 도제 축조에 따른 정온도 개선 효과분석)

  • Ryu, Kyong Ho;Jeong, Weon Mu;Kwon, Jinseong;Chang, Yeon S.;Baek, Won-Dae;Kim, Won Goung
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.32 no.4
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    • pp.230-241
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    • 2020
  • Since the construction of Pohang New Port, the problems of the low harbor tranquility caused by decreasing port operation rate has been continuously reported. In order to improve the harbor tranquility, a detached breakwater (DB) has been constructed outside the outer breakwater of Pohang New Port in 2018~2020. In this study, the effectiveness of the DB was proved by comparing the reduction rates of wave heights that were observed before and after the construction of the DB. First, the observed data were compared with the numerical model results available from a previous study, and the model data showed reasonable agreement with measured data at 3 out of 4 locations inside the port. The discrepancy in one of the locations was because the model could not accurately calculated the effect of wave interference in the inner corner of the port. The observation data showed excellent results that the number of waves that exceeded 0.3 m, the critical value to reach desired harbor tranquility, was significantly reduced after the construction of the DB. In addition, the reduction rate, the ratio of wave heights between outside and inside of the port, was decreased after the DB construction, which proved that properly designed coastal structures such as DB in this study could be effective in improving the port tranquility. The results of this study can be usefully applied for solving problems in similar cases.

Analysis of Water Quality Variation by Lowering of Water Level in Gangjeong-Goryong Weirin Nakdong River (낙동강 강정고령보 수위저하 운영에 따른 수질 변동특성 분석)

  • Park, Dae-Yeon;Park, Hyung-Seok;Kim, Sung-Jin;Chung, Se-Woong
    • Journal of Environmental Impact Assessment
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    • v.28 no.3
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    • pp.245-262
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    • 2019
  • The objectives of this study were to construct a three-dimensional water quality model (EFDC) for the river reach between Chilgok Weir and Gangjeong-Goryong Weir (GGW) located in Nakdong River, and evaluate the effect of hydraulic changes, such as water level and flow velocity, on the control of water quality and algae biomass. After calibration, the model accurately simulated the temporal changes of the upper and lower water temperatures that collected every 10 minutes, and appropriately reproduced changes in organic matter, nitrogen, phosphorus, and cyanobacteria. However, the simulated values were overestimated for the diatoms and green algae cell density, possibly due to the uncertainties of the parameters associated with algae metabolism and the lack of zooplankton predation function in the simulations. As a result of scenario simulation of running the water level of GGW from EL. 19.44 m to EL. 14.90 m (4.54 m drop), Chl-a and algae cell density decreased significantly.In particular,the cyanobacteria on the surface layer, which causes algal bloom, declined by 56.1% in the low water level scenario compared to the existing management level. The results of this study are in agreement with the previous studies that maintenance of critical flow velocity is effective for controlling cyanobacteria, and imply that hydraulic control such as decrease of water level and residence time in GGW is an alternative to limit the overgrowth of algae.

Long-Term Results of 2-Dimensional Radiation Therapy in Patients with Nasopharyngeal Cancer (이차원방사선치료를 시행한 코인두암 환자의 장기 추적 결과 및 예후인자 분석)

  • Lee, Nam-Kwon;Park, Young-Je;Yang, Dae-Sik;Yoon, Won-Sup;Lee, Suk;Kim, Chul-Yong
    • Radiation Oncology Journal
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    • v.28 no.4
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    • pp.193-204
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    • 2010
  • Purpose: To analyze the treatment outcomes, complications, prognostic factors after a long-term follow-up of patients with nasopharyngeal carcinoma treated with radiation therapy (RT) alone or concurrent chemoradiation therapy (CCRT). Materials and Methods: Between December 1981 and December 2006, 190 eligible patients with non-metastatic nasopharyngeal carcinoma were treated at our department with a curative intent. Of these patients, 103 were treated with RT alone and 87 patients received CCRT. The median age was 49 years (range, 8~78 years). The distributions of clinical stage according to the AJCC 6th edition included I: 7 (3.6%), IIA: 8 (4.2%), IIB: 33 (17.4%), III: 82 (43.2%), IVA: 31 (16.3%), IVB: 29 (15.3%). The accumulated radiation doses to the primary tumor ranged from 66.6~87.0 Gy (median, 72 Gy). Treatment outcomes and prognostic factors were retrospectively analyzed. Acute and late toxicities were assessed using the RTOG criteria. Results: A total of 96.8% (184/190) of patients completed the planned treatment. With a mean follow-up of 73 months (range, 2~278 months; median, 52 months), 93 (48.9%) patients had relapses that were local 44 (23.2%), nodal 13 (6.8%), or distant 49 (25.8%). The 5- and 10-year overall survival (OS), disease-free survival (DFS), and disease-specific survival (DSS) rates were 55.6% and 44.5%, 54.8% and 51.3%, in addition to 65.3% and 57.4%, respectively. Multivariate analyses revealed that CCRT, age, gender, and stage were significant prognostic factors for OS. The CCRT and gender were independent prognostic factors for both DFS and DSS. There was no grade 4 or 5 acute toxicity, but grade 3 mucositis and hematologic toxicity were present in 42 patients (22.1%) and 18 patients (9.5%), respectively. During follow-up, grade 3 hearing loss in 9 patients and trismus in 6 patients were reported. Conclusion: The results of our study were in accordance with findings of previous studies and we confirmed that CCRT, low stage, female gender, and young age were related to improvement in OS. However, there are limitations in the locoregional control that can be achieved by CCRT with 20 conventional radiation therapy. This observation has led to further studies on clarifying the efficacy of concurrent chemotherapy by intensity modulated radiation therapy.

Reproductive Ecology of the Silver Pomfret Pampus argenteus on the West Coast of Korea (한국 서해산 병어, Pampus argenteus의 번식생태)

  • Chung, Ee-Yung;Bae, Joo-Seung;Kang, Hee-Woong;Lee, Hwang-Bok;Lee, Ki-Young
    • Development and Reproduction
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    • v.12 no.2
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    • pp.169-181
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    • 2008
  • Reproductive ecology of the silver pomfret, Pampus argenteus were investigated by histological observations and morphometric data. Samples were collected by the stow net at the coastal area of Jaun-Do, Muan-gun, Korea, from January to December, 2006. P. argenteus is dioecious, the ovary is composed of many ovarian lobules, showing a pair of saccular structure, and the testis is composed of many seminiferous lobules, showing a pair of lobular structure. From February (growing stage) to September (after spawning), monthly changes in the gonadosomatic index, hepatosomatic index, and condition factor in females and males showed similar patterns with the gonad developmental phases. Judging from the results of their indice, it is assumed that spawning in females and males occur from May to July. The reproductive cycle can be classified into five successive stages in females: early growing stage (February to March), late growing stage (March to April), mature stage (March to July), ripe and spent stage (May to July), and recovery and resting stage (July to February); in males, the cycle can be divided into four successive stages: growing stage (February to April), mature stage (March to June), ripe and spent stage (May to July), and recovery and resting stage (July to February). According to the frequency distributions of egg diameters in the breeding season, P. argenteus is presumed to be spring-summer spawning species and polycyclic species to spawn 2 times or more during one spawning season. Number of total eggs in absolute fecundity were proportional to body length and body weight, respectively. Number of total eggs in absolute fecundity per body weight were also proportional to the body length, but if the increase of body weight considerably increased, rather total eggs in relative fecundity decreased with the increase of body weight. Percentage of first sexual maturity of P. argenteus were over 50% in females and males of 12.1 to 15.0 cm in body length, and 100% for fishes over 18.1 cm in length. Therefore, both sexes were regarded to be sexually mature at one year of age.

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