• Journal of IKEEE
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• v.23 no.2
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• pp.739-742
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• 2019

In this paper, we propose enhanced DAP(Dose Area Product). The development of enhanced DAP proposed in this paper has optimized the area dose meter that was developed previously. The development of enhanced DAP performed Optimized design of charge integrator and ADC circuit, optimization of line transceiver for RS-485 communication, optimization of display circuit, and optimization of PC-based control program for interlocking and aging. As a result of evaluating the performance of the proposed system in an accredited testing laboratory, Radiation dose dependence and Radiation quality dependence were measured to be 4.2%, which is below ${\pm}15%$ of international standard. Energy range/Tube voltage was confirmed in the range of 30~150kV. The sensitivity difference between sensor field and sensor field area dose sensitivity was measured to be 4.3%, and it was confirmed that it operates normally under ${\pm}15%$ of international standard. In order to measure the reproducibility of the area dosimeter, it was confirmed that it was 0% and it was operated normally at less than 2% of IEC60580 recommendation. Digital resolution was confirmed to be a minimum unit of $0.01{\mu}Gy{\cdot}m^2$ within the error range for the reference dose per hour.

• Korean Journal of Environmental Biology
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• v.37 no.1
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• pp.72-81
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• 2019

Bisphenol A (BPA), a representative endocrine disrupting chemicals, has adverse effects on growth, development and reproduction in aquatic organisms. The object of this study was to investigate the modulation of antioxidant enzyme-coding genes using quantitative real time RT-PCR (qRT-PCR), enzyme activity and total protein content, to understand oxidative stress responses after exposure to BPA for 48 h in brackish water flea Diaphanosoma celebensis. The BPA ($3mg\;L^{-1}$) significantly upregulated the expression of Cu/Zn-SOD, Mn-SOD, and catalase (CAT) mRNA. Three GST isoforms (GST-kappa, GST-mu, and GST-theta) mRNA levels significantly increased at the rate of $0.12mg\;L^{-1}$ of BPA. In particular, GST-mu showed the highest expression level, indicating its key role in antioxidant response to BPA. SOD activity was induced with a concentration-dependent manner, and total protein contents was reduced. These findings indicate that BPA can induce oxidative stress in this species, and these antioxidants may be involved in cellular protection against BPA exposure. This study will provide a better understanding of molecular mode of action of BPA toxicity in aquatic organisms.

• Clean Technology
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• v.25 no.3
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• pp.238-244
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• 2019

In this study, the ignition characteristics of petroleum-based aviation fuel (Jet A-1), bio aviation fuel (Bio-6308), and blended aviation fuel (50:50, v:v) were analyzed in accordance with change of temperature and pressure. The ignition delay time of each aviation fuel was measured by combustion research unit (CRU) and the compositions of the fuels were analyzed by GC/MS and GC/FID for qualitative and quantitative results. From the results, it was confirmed that the ignition delay times of all aviation fuels were shortened with increasing temperature and pressure. In particular, the effect of temperature was larger than the effect of pressure. Also, the ignition delay time of Jet A-1 was the longest at all measurement conditions, and it was judged that this result is because of the structurally stable characteristics of the benzyl radical generated during the oxidation reaction of the aromatic compound (about 22.48%) in Jet A-1. Also, it was confirmed that Jet A-1 had no section where the degree of shortening of ignition delay time was decreased by increasing temperature, which was because the benzyl radical inhibits the response that can affect the negative temperature coefficient (NTC). The ignition characteristics of blended aviation fuel (50:50, v:v) showed a similar tendency to those of Jet A-1, rather than to those of Bio-6308, so that the blended aviation fuel (50:50, v:v) can be applied to the existing system without any change.

• Korean Chemical Engineering Research
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• v.59 no.4
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• pp.514-520
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• 2021

A drug delivery system (DDS) based on nanoparticles has been used as a mediator to improve the efficacy of a drug by controlling the amount of drug released and delivering it to a target place. Chitosan, which is non-toxic and biodegradable, has good biocompatibility and excellent adsorption, so it can be used as a drug delivery vehicle. Valine, the essential amino acids, helps muscle growth and tissue recovery, and along with other amino acids. It lowers blood sugar levels and increases growth hormone production. In this study, Valine was adsorbed on magnetic chitosan which is capable of drug absorption, and Fe₃O₄-Valine CNPs was prepared through cross-linking with TPP (Tripolyphosphate). And then absorption and release trends of valine were investigated with the Fe₃O₄-Valine CNPs. Fe₃O₄, which has relatively high stability, is used to make the drug carrier magnetic so that the drug can be delivered to a target place. At optimal conditions, the absorption and release tendency of Fe₃O₄-Valine CNP was confirmed by analyzing by UV-Vis through the Ninhydrin test which is the color reaction of amino acids and by measuring the size of the particles, it was confirmed that it is suitable as a drug carrier.

• Journal of Life Science
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• v.31 no.1
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• pp.83-89
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• 2021

Uu-ilys, an i-type lysozyme from spoon worm (Urechis unicinctus), is an innate immune factor that plays an important role in the defense against pathogens. It also possesses non-enzymatic antibacterial activity. Thus, there is a possibility to develop an antimicrobial model peptide from Uu-ilys. In this study, we report the design, production, and antibacterial activity of an Uu-ilys analog that exhibits antibacterial activity. The Uu-ilys structure was fragmented according to its secondary structures to predict the regions with antimicrobial activity using antimicrobial peptide (AMP) prediction tools from different AMP databases. A peptide containing the C-terminal fragment was predicted to exert antimicrobial activity. The chosen fragment was designated as an Uu-ilys analog containing the C-terminal fragment, Uu-ilys-CF. To examine the possibility of developing an AMP using the sequence of Uu-ilys-CF, recombinant fusion protein (TrxA-Uu-ilys-CF) was produced in an expression system that was heterologous. The produced fusion protein was cleaved after methionine leaving Uu-ilys-CF free from the fusion protein. This was then isolated through high performance liquid chromatography and reverse phase column, CapCell-Pak C18. The antibacterial activity of Uu-ilys-CF against different microbial strains (four gram-positive, six gram-negative, and one fungal strain) were assessed through the ultrasensitive radial diffusion assay (URDA). Among the bacterial strains tested, Salmonella enterica was the most susceptible. While the fungal strain tested was not susceptible to Uu-ilys-CF, broad spectrum antibacterial activity was observed.

• Journal of the Korea Organic Resources Recycling Association
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• v.28 no.4
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• pp.23-33
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• 2020

Marine algae(Macro algae) are easily bio-degradable, and by-products are available as feed and fertilizer. The biomass of marine algae has higher CO2 absorption capacity than the wood system, and is highly valuable in use due to its fast growth speed and wide cultivation area without special cost for raw material production. In 2018, Marine algae production was 1,722,486ton, such as Saccharina japonica, Undaria pinnatifida and Porphyra tenera, the large amounts of by-products have been generated in the food processing facilities for commercialization. In this study, Saccharina japonica, Undaria pinnatifida were collected in the south coast region and Porphyra tenera was collected in the west coast region. The theoretical methane potential and biochemical methane potential(BMP) were analyzed, and Modified Gompertz model and Parallel first order kinetics model were adopted for the interpretation of the cumulative methane production curves. The theoretical methane potential of Saccharina japonica, Undaria pinnatifida and Porphyra tenera were 0.393, 0.373 and 0.435 N㎥/kg-VS, respectively. BMP obtained by the Modified gompertz model 0.226, 0.227, and 0.241 N㎥/kg-VS for Saccharina japonica, Undaria pinnatifida and Porphyra tenera, respectively. And BMP obtained by the Parallel first order kinetics model were 0.220, 0.243, and 0.240 N㎥/kg-VS for Saccharina japonica, Undaria pinnatifida and Porphyra tenera, respectively.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.40 no.6
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• pp.571-581
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• 2020

Vegetation affects water level change and flow resistance in rivers and impacts waterway ecosystems as a whole. Therefore, it is important to have accurate information about the species, shape, and size of any river vegetation. However, it is not easy to collect full vegetation data on-site, so recent studies have attempted to obtain large amounts of vegetation data using terrestrial laser scanning (TLS). Also, due to the complex shape of vegetation, it is not easy to obtain accurate information about the canopy area, and there are limitations due to a complex range of variables. Therefore, the physical structure of vegetation was analyzed in this study by reconfiguring high-resolution point cloud data collected through 3-dimensional terrestrial laser scanning (3D TLS) in a voxel. Each physical structure was analyzed under three different conditions: a simple vegetation formation without leaves, a complete formation with leaves, and a patch-scale vegetation formation. In the raw data, the outlier and unnecessary data were filtered and removed by Statistical Outlier Removal (SOR), resulting in 17%, 26%, and 25% of data being removed, respectively. Also, vegetation volume by voxel size was reconfigured from post-processed point clouds and compared with vegetation volume; the analysis showed that the margin of error was 8%, 25%, and 63% for each condition, respectively. The larger the size of the target sample, the larger the error. The vegetation surface looked visually similar when resizing the voxel; however, the volume of the entire vegetation was susceptible to error.

• Journal of the Korean Geotechnical Society
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• v.37 no.2
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• pp.5-17
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• 2021

The Moon has been an attractive planet as an outpost for deep space exploration since He-3 and water ice which can be used as energy resources were discovered. In-Situ Resource Utilization (ISRU) construction material fabrication method is required for sustainable space planet exploration. In this paper, the possibility of microwave sintering technology for construction material fabrication was evaluated using lunar regolith that can be easily collected from the Moon surface. Experimental assessment of the influence factors on microwave sintering was conducted using a hybrid sintering system for efficient processing. The heat distribution in the furnace was observed using thermal paper that is coated with a material formulated to change color when exposed to heat. Based on this result, sintered cylindrical KLS-1s with a diameter of 1 cm and a height of 2 cm were fabricated. Densities were measured for the sintered KLS-1s under rotating turntable conditions that have an effect of microwave dispersion. The more dielectrics were arranged, the more microwaves were dispersed reducing the heat concentration, and thus a uniformity of sintered KLS-1s was enhanced.

• Applied Chemistry for Engineering
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• v.22 no.5
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• pp.562-565
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• 2011

In this study, we developed a bioprocess using Clostridium ljungdahlii as a biological catalyst to produce bio-ethanol, and the effect of pH on microbial growth and ethanol production was investigated. From the results of fermentation at various initial pH condition without pH control, pH of fermentation broth decreased to 4.5 within 24 h due to accumulation of by-product acetic acid and both microbial growth and ethanol production were stopped. The experimental result of initial pH 8 showed the highest microbial growth and ethanol production (0.53 g/L), since the pH drop was relatively slow. From the experiment of pH 7 maintained fermentation using pH controllable bioreactor, the maximum cell dry weight of 1.65 g/L and the maximum ethanol concentration of 1.43 g/L were obtained within 24 h. In conclusion, the C. ljungdahlii growth was enhanced by pH maintenance of neutral range, and the ethanol production was also enhanced based on the growth-associated ethanol production characteristics of C. ljungdahlii.

• Journal of the Korean Applied Science and Technology
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• v.38 no.1
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• pp.241-262
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• 2021

This paper reviewed the necessity of a information and communication technology (ICT)-based smart livestock system as a development strategy for the animal life industry in the future. It also predicted the trends of livestock and animal food until 2050, 30 years later. Worldwide, livestock raising and consumption of animal food are rapidly changing in response to population growth, aging, reduction of agriculture population, urbanization, and income growth. Climate change can change the environment and livestock's productivity and reproductive efficiencies. Livestock production can lead to increased greenhouse gas emissions, land degradation, water pollution, animal welfare, and human health problems. To solve these issues, there is a need for a preemptive future response strategy to respond to climate change, improve productivity, animal welfare, and nutritional quality of animal foods, and prevent animal diseases using ICT-based smart livestock system fused with the 4th industrial revolution in various aspects of the animal life industry. The animal life industry of the future needs to integrate automation to improve sustainability and production efficiency. In the digital age, intelligent precision animal feeding with IoT (internet of things) and big data, ICT-based smart livestock system can collect, process, and analyze data from various sources in the animal life industry. It is composed of a digital system that can precisely remote control environmental parameters inside and outside the animal husbandry. The ICT-based smart livestock system can also be used for monitoring animal behavior and welfare, and feeding management of livestock using sensing technology for remote control through the Internet and mobile phones. It can be helpful in the collection, storage, retrieval, and dissemination of a wide range of information that farmers need. It can provide new information services to farmers.