• Parasites, Hosts and Diseases
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• v.23 no.1
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• pp.111-122
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• 1985

The present study was performed to observe the ultrastructure of the integument of adult Paragonimus westermani. Dogs experimentally infected with 60 metacercariae of F. westermani were autopsied 4 months after the infection. Adult p. westermani were extracted from the dogs and the fine structure was studied by means of scanning and transmission electron microscope. The findings are as follows: 1. Scanning electron microscopic findings showed that the spines and the papillae are distributed at whole body surface but the well developed spines or papaillae are shown around the oral sucker and ventral sucker. 2. At the end of the body, excretory pore was found, the shape was irregular. 3. Transmission electron microscopic findings showed that plasma membrane, tegument, basal lamina, connective tissue, circular muscle layer, longitudinal muscle layer. nerve axon and tegumental cell were observed. 4. In higher magnification, plasma membrance and bar-shaped granules were found at the outer surface of the tegument.

• Neonatal Medicine
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• v.16 no.2
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• pp.221-233
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• 2009

Purpose: Erythropoietin (EPO) has neuroprotective effects in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma, and excitotoxicity. Current studies have demonstrated the neuroprotective effects of EPO, but limited data are available for the neonatal periods. Here in we investigated whether recombinant human EPO (rHuEPO) can protect the developing rat brain from HI injury via modulation of NMDA receptors. Methods: In an in vitro model, embryonic cortical neuronal cell cultures from Sprague-Dawley (SD) rats at 19-days gestation were established. The cultured cells were divided into five groups: normoxia (N), hypoxia (H), and 1, 10, and 100 IU/mL rHuEPO-treated (H+E1, H+ E10, and H+E100) groups. To estimate cell viability and growth, a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay was done. In an in vivo model, left carotid artery ligation was performed on 7-day-old SD rat pups. The animals were divided into six groups; normoxia control (NC), normoxia Sham-operated (NS), hypoxia-ischemia only (H), hypoxia-ischemia+vehicle (HV), hypoxia-ischemia+rHuEPO before a HI injury (HE-B), and hypoxia-ischemia+rHuEPO after a HI injury (HE-A). The morphologic changes following brain injuries were noted using hematoxylin and eosin (H/E) staining. Real-time PCR using primers of subunits of NMDA receptors (NR1, NR2A, NR2B, NR2C and NR2D) mRNA were performed. Results: Cell viability in the H group was decreased to less than 60% of that in the N group. In the H+E1 and H+E10 groups, cell viability was increased to >80% of the N group, but cell viability in the H+E100 group did not recover. The percentage of the left hemisphere area compared the to the right hemisphere area were 98.9% in the NC group, 99.1% in the NS group, 57.1% in the H group, 57.0% in the HV group, 87.6% in the HE-B group, and 91.6% in the HE-A group. Real-time PCR analysis of the expressions of subunits of NMDA receptors mRNAs in the in vitro and in vivo neonatal HI brain injuries generally revealed that the expression in the H group was decreased compared to the N group and the expressions in the rHuEPO-treated groups was increased compared to the H group. Conclusion: rHuEPO has neuroprotective property in perinatal HI brain injury via modulation of N-methyl-D-aspartate receptors.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.17 no.3
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• pp.138-148
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• 2005

Dynamic response of floating structures such as floating body and floating bridges subject to wave load is to be calculated in frequency domain. Added mass coefficient, damping coefficient and wave exciting force are obtained numerically from frequency domain formulation of linear potential theory and boundary element method for a floating body which is partially submerged into water and subjected to wave force. Next, the equation of motion for the dynamic behavior of a floating structure which is supported by the floating bodies and modeled with finite elements is written in frequency domain. hker a hemisphere is analyzed and compared with the published references as examples of floating bodies, the hydrodynamic coefficients for a pontoon type floating body which supports a floating bridge are determined. The dynamic response of the floating bridge subject to design wave load can be solved using the coefficients obtained for the pontoons and the results are plotted in the frequency domain. It can be seen from the example analysis that although the peak frequency of the incoming wave spectrum is near the natural frequency of the bridge, the response of the bridge is not amplified due to the effect that the peak frequency of wave exciting force is away from the natural frequency of the bridge.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.7
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• pp.779-784
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• 2014

This study provided the analytical model describing the friction-induced noise in the ball joint system under the edge loading condition. The frictional and conformal contact kinematics between the spherical bearing and the hemispherical socket was derived and the dynamic equations of the perturbed motion were established. The numerical results revealed that the bending modes of the ball joint system can become unstable due to friction, and the axial load and contact stiffness strongly influenced the dynamic instability. In contrast, the tilting angle of the socket was not found to significantly contribute to the dynamic instability of the ball joint.

• Journal of the Mineralogical Society of Korea
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• v.24 no.2
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• pp.111-118
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• 2011

Hydrated halloysite was formed by the low temperature alteration of trachytic tuff in onion-like spherical or curly platy forms. The Si content was higher than that of ideal kaolin minerals, indicating the possible presence of amorphous materials. The high Fe content is responsible for the platy morphology of halloysite. The leached ions precipitated as halloysite filling the interparticle pores, while trachytic glass was replaced by Si-rich amorphous materials in an hemispherical form, which was further evolved into spherical halloysite. Halloysite is one of the major alteration products of the volcanic ash in Ulleung Island underwent intense trachytic volcanism.

• The Korean Journal of Zoology
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• v.20 no.2
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• pp.109-122
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• 1977

Ultraviolet irradiation of the vegetal hemisphere of the fertilized frog egg prior to first cleavage resulted in alterations in neural morphogenesis. The sensitivity to UV irradiation dropped drastically at the point of 2/3 time lapse between fertilization and the appearance of the first cleavage furrow. Scannining electron micrographs revealed a decrease in size of the cells on the surface of the irradiated embryos. However, ectoderm exchange frafts indicated that the ectoderm of the irradiated embryo retains its capaciiy to form a completely normal neural morphology and epidermal surface. These facts were interpreted in terms of a decrease in the capacity for invagination during gastrulation, and subsequent primary embryonic induction.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.11
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• pp.914-921
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• 2017

The experimental research on a high-altitude environment simulation of space launch vehicle is important for securing independent technologies with launching space vehicles and completing missions. This study selected an altitude of 65 km for the experiment environment where it exceeded Mach number of 6 after the launch of Korean Space Launch Vehicle(KSLV-II). Shock tunnel was used to replicate the flight condition. After flow establishment, in order to confirm aerodynamic characteristics and normal and oblique shockwaves, the flow verification was carried out by measuring stagnation pressure and heat flux of a forebody model, and shockwave stand-off distance of a hemispherical model. In addition, a shock-free technique to recover free-stream condition has been developed and verified. From the results of the three verification tests, it was confirmed that the flow was replicated with the error of about ${\pm}3%$. The error between the slope angle of inclined shockwave of the scaled down transition section model using the shock-free shape and the slope angle of the horizontal plate model, and between the theoretical and the experimental value of the static pressure of the model were confirmed to be 2% and 1%, respectively. As a result, the efficiency of the shockwave cancellation technique has been verified.

• Progress in Medical Physics
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• v.9 no.2
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• pp.95-104
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• 1998

The dynamic properties of the 3rd-order neuron of the retina was investigated by using conventional intracellular recording techniques. Experiments were performed in the superfused retina-eyecup preparation of the channel catfish, Ictalurus punctatus. The cornea, iris, lens, and vitreous were removed by absorption with Kimwipe tissue under the dissection microscope thereby exposing the retina in a hemi -eyecup. The electrical signal was amplified by electrometer, viewed on oscilloscope. Regular signals from the cells were recorded on a penwriter and stored by data recorder and computer. Full-field, spot or annular light stimuli were generated on a computer monitor and focused onto the retina. Baclofen hyperpolarized the dark membrane potential, suppressed sustained component and enhanced transient component of the ON-sustained cell with a large transient component, but did not affect the surround antagonism of the cell. Baclofen selectively suppressed responses evoked by moving bar light stimuli on the ON-OFF transient cell. The results suggest that transient cells have directional selectivity in the inner retina. These dynamic properties of amacrine and ganglion cells were modulated by baclofen. Therefore, it is presumed that there is baclofen-induced directional selectivity in ON-OFF transient cells in the catfish retina.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.1
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• pp.23-32
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• 2016

Various studies have been conducted for drag reduction of a high-speed vehicle by injecting counterflow jet from its nose cone. In this study, in order to obtain baseline data and key parameters for drag reduction method, the counterflow jet study of the USA is reviewed and summarized. The nose cone shapes of each study are hemisphere cylinder, truncated cone, and reentry capsule, and their test conditions are summarized accordingly. Key parameters for drag reduction are jet mach number, mass flow rate, and pressure ratio. Even though drag reduction effects show various results according to given test conditions, it is found that the drag reduction effect reaches up to 40~50%.

• The Journal of the Acoustical Society of Korea
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• v.33 no.1
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• pp.10-20
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• 2014

To study the water-entry impact noise, on-board experiment using a small launcher firing various objects was performed in the Yellow Sea. As the launcher fires a cylindrical object from the ship vertically, generated noise is measured with a hydrophone on the starboard of Chung-hae, Marine surveyor. Three types of cylindrical objects, which have noses of flat-faced, conical, and hemisphere, were used during the experiment. The measured noise exhibits a time-dependency which can be divided into three phases: (1) initial impact phase, (2) open cavity flow phase, (3) cavity collapse and bubble oscillation phase. In most cases, the waveform of bubble oscillation phase is dominant rather than that of initial impact phase. Pinch-off time, where a cavity begins to collapse, occurs at 0.18 ~ 0.2 second and the average lasting time of bubble was 0.9 ~ 1.3 second. The energy of water-entry impact noise is focused in the frequency region lower than 100 Hz, and the generated noise is influenced by the nose shapes, object mass, and launching velocity. As a result, energy spectral density on the bubble frequency is higher in the order of flat-faced, conical, hemisphere nose, and the increase of initial energy raises the energy spectral density on the bubble frequency in the cylinder body of same shape. Finally, we compare the measurements with the simulated signals and spectrum based on the bubble explosion physics, and obtain satisfactory agreements between them.