• Journal of the Korea Convergence Society
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• v.10 no.11
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• pp.209-215
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• 2019

The most important personal health care in digital health care is a very important issue mainly for chronic diseases. Therefore, it is important to develop a simple wearable device for real-time health management. Existing blood pressure estimation wearable devices use PPG characteristics to analyze PTT and propose blood pressure estimation algorithms. However, the influencing factors of the algorithm such as the reproducibility of PPG, whether to apply various PTTs, and variables generated from the physical differences of the measurers are actually very complex. Therefore, in this study, the correlation between PTT, SBP, and DBP was analyzed, and it was designed to use PPG sensors for device miniaturization. The blood pressure estimation algorithm took into account differences in PPG, heart rate, and personal variables.

• Journal of Convergence for Information Technology
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• v.7 no.2
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• pp.83-90
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• 2017

To launch the product recently attached to IoT consumer electronics, smart phones and healthcare products around the large companies is a trend that is growing interest in the IoT. However, the country's small business environment is what the environmental improvement process that is easily accessible to the small business environment because the IoT technologies are difficult to apply the IoT technologies than any other country environment than desperate situation. In this paper, we propose a service operating model to improve production efficiency when the fusion manufacturing process is currently operating in the country SMEs and IoT technology. Proposed model using the manufacturing product information and sensor / dabayiseu information in the entire manufacturing process has as its object to utilize the IoT technology. Performance evaluation, the proposed model is more efficient than the previous model and 23.1% of the manufacturing process. In addition, it is increasing the manufacturing process was reduced by 17.3%, the average processing time as compared to the previous model. Finally, the personnel cost to be used in the manufacturing process was found to be an average decrease of 19.8% than previous model.

• The Journal of Korean Institute of Information Technology
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• v.17 no.12
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• pp.21-28
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• 2019

Side effects of drugs mean harmful and unintended effects resulting from drugs used to prevent, diagnose, or treat diseases. These side effects can lead to patients' death and are the main causes of drug developmental failures. Thus, various methods have been tried to identify side effects. These can be divided into biological and systems biology approaches. In this study, we use systems biology approach and focus on using various phenotypic information in addition to the chemical structure and target proteins. First, we collect datasets that are used in this study, and calculate similarities individually. Second, we generate a set of features using the similarities for each drug-side effect pair. Finally, we confirm the results by AUC(Area Under the ROC Curve), and showed the significance of this study through a comparison experiment.

• Geophysics and Geophysical Exploration
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• v.25 no.1
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• pp.1-13
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• 2022

For surveying shallow gas reservoirs in the Pohang basin, we proposed a seismic exploration method applicable to the transition zone in which land and marine areas are connected. We designed the seismic acquisition geometry considering both environments. We installed land nodal receivers on the ground and employed vibroseis and airgun sources in both land and marine areas. For seismic exploration in the transition zone, specific acquisition and processing techniques are required to ensure precise matching of reflectors at the boundary between the onshore and offshore regions. To enhance the continuity of reflection events on the seismic section, we performed amplitude and phase corrections with respect to the source types and applied a static correction. Following these processing steps, we obtained a seismic section showing connected reflectors around the boundary in the transition zone. We anticipate that our proposed seismic exploration method can also be used for fault detection in the transition zone.

• Health Policy and Management
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• v.34 no.3
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• pp.238-248
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• 2024

The recent coronavirus disease 2019 pandemic has accelerated market growth by promoting opportunities and advancements in drug development and vaccine manufacturing. Despite the rapid expansion of the global bio market, South Korea's bio market holds a relatively small share. To address this, the government is implementing various strategies, including the establishment of bio clusters, to foster innovation and growth in the bio industry. This study focuses on Korea's HongNeung bio cluster and conducts a comparative analysis with the Boston Bio Cluster in the United States and the Biopolis in Singapore. By examining the development history, structure, and success factors of these clusters through three categories-infrastructure, internal components, and policies and systems-commonalities and differences among the clusters are analyzed. Subsequently, development strategies for the HongNeung bio cluster are proposed. For the HongNeung bio cluster to grow into a leading bio cluster, strong government support, expansion of innovative infrastructure, talent acquisition, and the implementation of customized policies such as strategic partnerships are necessary. Additionally, the establishment of active collaboration and exchange systems with overseas bio clusters is required.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.2
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• pp.81-90
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• 2013

During the past decade, many changes and attempts have been tried and are continued developing new technologies in the computing area. The brick wall in computing area, especially power wall, changes computing paradigm from computing hardwares including processor and system architecture to programming environment and application usage. The high performance computing (HPC) area, especially, has been experienced catastrophic changes, and it is now considered as a key to the national competitiveness. In the late 2000's, many leading countries rushed to develop Exascale supercomputing systems, and as a results tens of PetaFLOPS system are prevalent now. In Korea, ICT is well developed and Korea is considered as a one of leading countries in the world, but not for supercomputing area. In this paper, we describe architecture design of MAHA supercomputing system which is aimed to develop 300 TeraFLOPS system for bio-informatics applications like human genome analysis and protein-protein docking. MAHA supercomputing system is consists of four major parts - computing hardware, file system, system software and bio-applications. MAHA supercomputing system is designed to utilize heterogeneous computing accelerators (co-processors like GPGPUs and MICs) to get more performance/$, performance/area, and performance/power. To provide high speed data movement and large capacity, MAHA file system is designed to have asymmetric cluster architecture, and consists of metadata server, data server, and client file system on top of SSD and MAID storage servers. MAHA system softwares are designed to provide user-friendliness and easy-to-use based on integrated system management component - like Bio Workflow management, Integrated Cluster management and Heterogeneous Resource management. MAHA supercomputing system was first installed in Dec., 2011. The theoretical performance of MAHA system was 50 TeraFLOPS and measured performance of 30.3 TeraFLOPS with 32 computing nodes. MAHA system will be upgraded to have 100 TeraFLOPS performance at Jan., 2013.

• Korean Journal of Microbiology
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• v.49 no.3
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• pp.245-252
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• 2013

Pseudomonas aeruginosa and Acinetobacter baumannii are significant opportunistic pathogens in hospitals and are resistant to most antibiotics. Multidrug-resistant P. aeruginosa (MDRPA) and A. baumannii (MDRAB) cause severe human nosocomial infections and are more difficult to treat than methicillin-resistant Staphylococcus aureus (MRSA). Bifidobacteria are among of the most beneficial probiotics and have been widely studied for their antimicrobial activities. The present study explored the antimicrobial activity of Bifidobacterium sp. isolated from healthy Koreans against MDRPA and MDRAB. The antimicrobial activity of the isolates against MDRPA and MDRAB, which are resistant to ciprofloxacin, tobramycin, gentamicin, meropenem, and ceftazidime, was determined by modified broth microdilution methods using absorbance. Among all tested bifidobacteria isolates (nine B. adolescentis, three B. longum, and two B. pseudocatenulatum), the culture supernatant of B. pseudocatenulatum SPM1309 showed a strong growth inhibitory effect against MDRPA and MDRAB. No change in the turbidity of the mixture was observed during incubation, and its inhibitory effect occurred through bacteriostastic action. Moreover, the antibacterial activity was observed in the fraction with molecular weights <10 kDa of bifidobacteria culture supernatant, and the active fraction was heat-stable because it maintained its activity when heated at $70^{\circ}C$ for 10 min. The results suggest that this Bifidobacterium strain could have potential applications for alternative therapy in MDRPA and MDRAB infections.

• Tuberculosis and Respiratory Diseases
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• v.56 no.2
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• pp.203-209
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• 2004

Background : Methotrexate (MTX) has been used to treat a wide range of malignant and benign diseases including osteosarcoma, advanced stage non-Hodgkin's lymphoma, psoriasis, severe rheumatoid arthritis, sarcoidosis, and Wegener's granulomatosis. MTX-induced lung injury occurs in up to 10% of treated patients. Although both acute and chronic presentations have been described, typical manifestation of MTX-induced lung injury is subacute with symptoms usually developing within several months after starting therapy. Nonspecific interstitial pneumonia (NSIP) is the most common histopathologic manifestation of MTX-induced lung disease, while bronchiolitis obliterans organizing pneumonia (BOOP) and diffuse alveolar damage (DAD) are less common. Granuloma formation is reported in 34.7%. In Korea, Two reports of MTX pneumonitis have been published. The one presented with NSIP and the other with DAD. We recently experienced a case of MTX pneumonitis with presentation of hypersensitivity pneumonitis.

• Fire Science and Engineering
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• v.28 no.1
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• pp.37-43
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• 2014

The high predictive performance of fire detector models is essentially needed to assure the reliability of fire and evacuation modeling in the process of Performance-Based fire safety Design (PBD). The main objective of the present study is to measure input information in order to predictive the accurate activation time of fixed temperature heat detectors adopted in Fire Dynamics Simulator (FDS) as a representative fire model. To end this, Fire Detector Evaluator (FDE) which could be measured the device properties of detector was used, and the spot-type fixed temperature heat detectors of two thermistor types and one bimetal type were considered as research objectors. Activation temperature and Response Time Index (RTI) of detectors required for the fire modeling were measured, and then the RTI was measured for ceiling jet flow and vertical jet flow in consideration of the install location of detectors. The results of fire modeling using measured device properties were compared and validated with the experimental results of full-scale compartment fires. It was confirmed that, in result, the numerically predicted activation time of detector showed reasonable agreement with the measured activation time.

• The Journal of the Korea Contents Association
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• v.12 no.9
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• pp.194-201
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• 2012

The expansion of media is in close connection with the expansion of awareness. The invention of characters enabled mankind to cross over time and space. Machines led to the development of body functions and electricity led to the expansion of space and time. Computers are the extension of the human brain and the advent of the internet led to the expansion of relationships. Even at this moment, media is unremittingly progressing like a spread of a mutant virus, and has resulted in fusion and complex phenomena such as convergence and hybrid media. Transmedia is a compound word formed by the word "Trans" which means traverse, transcend, penetrate or change, and the word "Media" and has the meaning "media which transcends media" which embraces all of modern day media. However, unlike other fusion or complex media, it is different in that it is not a combination of technologies but a combination of technology and emotion. Thus, transmedia should be recognized as a form of media that carries a significant meaning from the user experience aspect as it must simultaneously satisfy both "emotional awareness", which appeals to the human emotion, and "conscious awareness" of mankind, which arises out of the digital technology considered to be important in the smart-era society. This study first examines the concept of transmedia, and then examines the role of user experience design which triggers conscious thinking and strategies for emotional marketing. This study aims to be recognized as a matter for consideration with respect to the development stage for the establishment of a steady communication relationship between developers and designers, as well as communication with users.