• Title/Summary/Keyword: 미숙

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An Experimental Study of Radioprotective Effect of Ginseng Alkaloid Fraction on Cellular Damage (방사선 세포 손상에 대한 인삼 Alkaloid 분획의 보호 효과에 관한 실험적 연구)

  • Yoo, Seong-Yul;Cho, Chul-Koo;Kim, Mi-Sook;Yoo, Hyung-Jun;Kim, Seong-Ho;Kim, Tae-Hwan
    • Journal of Radiation Protection and Research
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    • v.22 no.3
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    • pp.195-205
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    • 1997
  • This paper is to assess the effect of Adaptagen as a radioprotector in which main component is alkaloid fraction of ginseng. Evaluation was made in vitro and in vivo study with NIGP(S) mouse by the measurement of regeneration of jejunal crypt cell and micronucleus assay to analyze radioprotective effect of ginseng alkaloid fraction in comparison with that of water fraction after whole body irradiation. The results were as follows, 1. The degree of radiation damage of mouse jejunal crypt cell was diminished in both of alkaloid and water fraction groups compared to control group but more in alkaloid fraction group than water fraction group. Regeneration of mouse jejunal crypt cell was higher both in alkaloid and water fraction groups than control group. 3. In vitro study, frequency of micronucleus was diminished in tendency for the treated groups than control group but statistically insignificant. 4. In vitro study, frequency of micronucleus was diminished in both alkaloid and water fraction groups compared to control group but more in alkaloid fraction group than water fraction group.

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Prognostic Significance of Fascin Expression in Stage I Non-small Cell Lung Cancer (수술 절제를 시행받은 제1기 비소세포폐암 환자에서의 Fascin 발현과 예후)

  • Roh, Mee-Sook;Um, Su-Jung;Choi, Youngmin;Kim, Ki-Nam;Choi, Pil Jo;Lee, Soo-Keol;Son, Choonhee;Yang, Dookyung
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.2
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    • pp.105-109
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    • 2008
  • Background: Fascin is an actin-bundling protein that plays an important role in cellular motility. Fascin is normally expressed in the neuronal and mesenchymal cells and its expression is low or absent in the epithelia. However, an overexpression of fascin has been linked to the invasive behavior of some neoplasms such as breast, stomach and ovarian tumors. In this study, we evaluated the expression of fascin and its prognostic significance in stage I non-small cell lung cancer (NSCLC). Methods: Immunohistochemical staining for fascin was performed on the paraffin-embeded tissue sections of 81 cases of resected NSCLC. Staining of more than 5% of the tumor cells was recorded as positive immunoreactivity. Results: Fascin expression was seen in 73% (59/81) of the cases and this was more frequently seen in squamous cell carcinoma than in adenocarcinoma (93% vs 42%). There were no significant correlations of fascin immunoreactivity with tumor recurrence and overall survival. Conclusion: The expression rate of fascin was relatively high in NSCLC, but this was without prognostic significance. The exact clinical role of fascin should be defined through further investigations.

The comparative study on changes in job satisfaction and turnover intention according to the convergence mediating factors and the level of emotional labor in dental hygienists (치과위생사의 감정노동수준과 매개변수 융합에 따른 직무만족 및 이직의도 변화 비교 연구)

  • Choi, Mi-sook;Ji, Dong-ha
    • Journal of the Korea Convergence Society
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    • v.6 no.6
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    • pp.27-34
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    • 2015
  • Abstract The purpose of this study is to analyze the changes in job satisfaction and turnover intention according to the level of Emotional labor and the mediating effect in dental hygienists. Higher levels of emotional labor resulted in lower levels of job satisfaction, as well as higher levels of turnover intention. We used the logistic regression analysis to compare change of job satisfaction, turnover intention according to the level of emotional labor. In logistic regression analyses, social support was the largest mediating factor between emotional labor and job satisfaction and the odds(Likely to with low job satisfaction) was down by 16% after adjustment for supervisor, colleague. In case of turnover intention, largest mediating factor were drinking, physical condition, supervisor, colleague and the odds(Likely to with high turnover intention) was down by 52% after adjustment for mediating factors. The results of this study were as follows. Emotional labor was negatively impact on job satisfaction and turnover intention. To increase the job satisfaction and lower the turnover intention, it is necessary to do more efforts to improve social support(supervisor and colleague) and management personal factor(drinking, physical condition) for the dental hygienists should be made to reduce such negative effects.

Analyzing the Effect of Changes in the Benchmark Policy Interest Rate Using a Term Structure Model (이자율 기간구조를 이용한 정책금리 변경의 효과 분석)

  • Song, Joonhyuk
    • KDI Journal of Economic Policy
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    • v.31 no.2
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    • pp.15-45
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    • 2009
  • This paper estimates the term structure of interest rates with the setup of 3-factor no arbitrage model and investigates the trend of term premia and the effectiveness of changes in policy interest rates. The term premia are found to be high in a three-year medium term objective, which can be interpreted as reflecting the recognition of investors who expect a higher uncertainty in real activities for the coming three years than for a longer term. Then, in order to look into the effect of policy interest rates after the recent change of benchmark interest rate, this paper analyzes the effects of the changes in short-term interest rates of the financial market on the yield curve of the bond market at time of change. Empirical results show that the discrepancy between call rate, short-term rate in money market, and instantaneous short rate, short-term rate in the bond market, is found to be significantly widened, comparing to the periods before the change in benchmark interest rate. It is not easy to conclude clearly for now whether such a widening gap is caused by the lack of experiences with managing new benchmark interest rate or is just an exceptional case due to the recent turmoil in the global financial market. However, monetary policy needs to be operated in a manner that could reduce the gap to enhance its effectiveness.

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Effect of Fermentation Temperature on Quality Characteristics of Apple Wine (발효온도가 사과와인 품질 특성에 미치는 영향)

  • Kwak, Han Sub;Seo, Jae Soon;Bae, Haejung;Lee, Hwajong;Lee, Youngseung;Jeong, Yoonhwa;Kim, Misook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.1
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    • pp.155-159
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    • 2016
  • The objective of this study was to investigate the effect of fermentation temperature on quality characteristics of apple wine. Apple wine mashes were fermented in 15, 20, and $25^{\circ}C$ water bathes for 9 days. The pH levels of all samples were below 4 from 24 h of fermentation until the end. Total acidities of 0.05% acetic acid solution were 7.8, 7.4, and 7.0% in the 15, 20, and $25^{\circ}C$ fermented samples, respectively. The evaporation of esters generated by combining alcohol and organic acids might be the reason for lower total acidity for high temperature fermentation. Alcohol contents of the 20 and $25^{\circ}C$ fermented samples were 6.5 and 6.6% (v/v), respectively, whereas that of the $15^{\circ}C$ fermented sample was 5.6% (v/v) and significantly lower than the others (P<0.05). Methanol contents were 0.68, 0.82, and 1.69 mg/L in the 15, 20, and $25^{\circ}C$ fermented samples, respectively. Fermentation at higher temperatures generated higher methanol content in apple wine. On the other hand, acetaldehyde contents were 3.43, 2.39, and 1.02 mg/L in the 15, 20, and $25^{\circ}C$ fermented samples, respectively, due to the lower boiling point of acetaldehyde ($20.2^{\circ}C$). Based on the results, a fermentation temperature of $20{\sim}25^{\circ}C$ is effective for apple wine fermentation.

A Study on the Perception of Elementary School Students and their Parents on Internet Ethics(Focusing on the Influences of the Parents on the Internet Usage of their Children) (초등학생과 학부모의 인터넷 윤리의식에 관한 연구 (부모가 자녀의 인터넷 이용에 미치는 영향을 중심으로))

  • Kang, Sung-Hee
    • Journal of The Korean Association of Information Education
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    • v.12 no.2
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    • pp.213-222
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    • 2008
  • The information society based on Internet has positive effects to provide us with abundance and comfort as well as enhancement of quality of life. But it also has negative effects which bring about more serious social problems than real life. These negative effects of the cyber space are especially critical to elementary school students who do not have good judgment capability and clear concept on cyber space. To solve these problems, we have to let them have ethical sense to respond to the dysfunctions of Internet. We need to enforce Internet ethics education at home and in school so that they can behave as responsible and moral behaviors in this information society. Because the most of the elementary school students usually use Internet at home, the role of their parents can be particularly important factor in Internet ethics education. The purpose of this paper was to identify the current status of the consciousness on Internet ethics of the elementary school students who are the creators of new culture on Internet and their parents who make great influence on their education, and to study what influence the consciousness on the Internet ethics of parents has made on the Internet usage of their children. Through this study, we try to provide the desirable direction for Internet ethics of elementary school students.

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The Clinical Study on Bee Venom Acupuncture Treatment of Patient with Thoracolumbar Compression Fracture (봉약침(蜂藥鍼) 치료(治療)를 병행(竝行)한 흉(胸)·요추압박골절(腰椎壓迫骨折) 환자(患者)의 임상적(臨床的) 고찰(考察))

  • Lee, Seong-no;Hong, Seo-young;Byun, Im-jeung;Ahn, Koang-hyun;Kwon, Soon-jung;Song, Won-sub;Kang, Mi-suk;Song, Ho-sueb;Kim, Kee-hyun
    • Journal of Acupuncture Research
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    • v.19 no.6
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    • pp.35-48
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    • 2002
  • Objective : The study was performed to evaluate the effect of treatment for thoracolumbar compression fracture by using Bee Venom Acupuncture that is well known for anti-inflammatory and analgesic effect. Methods : We investigated 39 cases of patient with thoracolumbar compression fracture. The patients with thoracolumbar compression fracture were treated at the department of acupuncture & moxibustion of Kyung-Won University Oriental Hospital from 1st January 2001 to 30th August 2002. We selected for two groups. One group was treated by Bee Venom Acupuncture therapy(Bee Venom Acupuncture Group : BAG), the other group was treated by Filiform Acupuncture therapy(None Bee Venom Acupuncture Group : NBAG). Results : 1. The distribution showed female predominance in sex and 70's predominance in age. The largest group was "accidental fall" and the next was "lifting heavy objects" in causes, and within 2 weeks in the duration of disease 2. In the duration of admission, the largest group was within 4 weeks. In regard to level of injury, T12 was found to be most predominant, followed in turn by L1, L2, L5. In regard to grade of clinical symptoms, Grade III was most predominant, followed by Grade II, Grade IV. 3. In the results of treatment, 87.5% were above "Good" in BAG and 47.8% in NBAG. 4. In the result of treatment due to the grade of clinical symptoms, BAG was more excellent than NBAG on the whols grade. 5. In the result of treatment due to duration of admission, the duration of admission was not in proportion to the results of treatment. 6. In the change of lumber flexion, the improvement above $80^{\circ}$ was 50% in BAG and 21.7% in NBAG 7. In the stability of treatment, the BAG and NBAG did't show any detrimental change in GOT, GPT, r-GTP, BUN, creatinine. Conclusions : In the treatment of thoracolumbar compression fracture, the Bee Venom Acupuncture can be regarded as more effective treatment than Filiform Acupuncture in the clinical practice. This is expected to be available for clinical use.

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A Comparative Study on the Growth & Developmental Status of Premature and Full Term Infants During the First 3Years (미숙아와 정상아의 영유아기 성장발달상태 비교연구)

  • 박영애
    • Journal of Korean Academy of Nursing
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    • v.15 no.3
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    • pp.62-73
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    • 1985
  • The problems of growth & development due to maladjustment are gradually increasing while need for the treatment of children's diseases is decreasing. The level of developmental deficiency or delay correlates with neonatal birth weight and also with gestational age, i.e. degrees of prematurity. There-fore, developmental defects and potential risk factors' are more Common in premature infants than in full term infants. The purpose of this study is to define the difference in the growth at developmental status between premature and full term infants, and to define the relation between the developmental status and the physical growth during the first 3 years' Data were collected from January 10, 1985 to April 6, 1985 at 3 hospitals including St. Mary's Hospital, and through home visiting. The subjects of this study consisted of 79 Premature infants (G.A. <37wks. & B.W. <2.5kg) and 94 full term infants (G.A.≥37 wks. & B.W.≥2.5kg). The study method used was a questionnaire, anthropometric assessment and DDST for normative data of growth & development. The collected data were analyzed using descriptive statistics, chi-square test and t-test. The results of the study were as follows: Hypothesis: 1 : That the prematures will differ from the full term infants in the physical growth status during the first 3 years was partially supported (p<0.02) : The prematures reached up the full term infants in the physical growth status in the first 6 months. And, the first hypothesis was supported (P<0.01) : There are more cases which is below‘the Korean children's physical. growth standards’in prematures than in full term infants. Hypothesis 2 : That the prematures will differ from the full term infants in the developmental status during the first 3 years was supported (P< 0.001);‘Normal’developmental status due to DDST was less in prematures than in full term infants. And, the second hypothesis was Partially supported (P<0.02) : The developmental status of the pre-matures was different from that of the full term infants within the first 3 months by analysis of passed items in DDST, Hypothesis 3 : That the prematures' developmental status will relate to their physical growth during the first 3 years was supported (P<0.001) : If the prematures' developmental status is in delayed status, then, their physical growth status is also in delayed status. This study shows that the prematures differed significantly from the full term infants in the growth at developmental status during their infancy. This means that the nurse can foster the growth & development of the prematures by supportive care during their infancy. Further longitudinal study is needed to verify these findings for the environmental factors.

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The Influence of Family Support Degree on the Depression of the Elderly in a Rural Area (일부(一部) 농촌노인(農村老人)이 지각한 가족지지(家族支持)가 우울에 미치는 영향(影響))

  • Kim, Mi-Suk;Kim, Ki-Soon;Park, Jong;Cho, Yong-Rae;Kim, Yang-Ok
    • Journal of agricultural medicine and community health
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    • v.24 no.1
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    • pp.115-129
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    • 1999
  • To find the influence of family support degree on the depression of the elderly in a rural area, a questionnaire survey was made toward 163 persons who were more than 65 years old and living in a township at Chollanamdo province from January 1st to February 20th, 1998. The major findings are as follows : 1. By simple analysis significantly associated variables with depression score were residence, adequacy of pocket money, health consciousness, drinking alcohol, smoking, score of activity of daily living(ADL), score of instrumental activities of daily living(IADL), and degree of family support among female respondents(p<0.05). 2. To find the influence of family support on the depression score excluding other associated variables, multiple regression analysis was made and it was found that family support was associated significantly with affective, somatic, psychomotor and psychological domain of depression score among male, and somatic, psychomotor and psychological domain among female(p<0.05). The above finding suggest that family support degree is an important factor to be associated with the depression of the elderly in the rural area. So to deal with the depression of rural elderly, how to make close relation among family members must be considered.

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A Study on Exercise Intervention for Improving Physical Activity for the Disabled: From the Perspective of Convergence Device (장애인 신체활동 증가를 위한 운동중재에 관한 연구: 융합형 디바이스 활용 관점에서)

  • Kang, Sunyoung
    • Convergence Security Journal
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    • v.19 no.5
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    • pp.85-90
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    • 2019
  • The purpose of this study is to analyze the trend of exercise intervention applying various devices to increase the physical activity of the disabled, and to suggest the exercise intervention using converged devices that meet the needs of the times due to the increase of elderly people with disabilities. Exercise intervention using converged devices applicable to the disabled is divided into two types: first, exercise intervention using virtual reality-based gamification, and second, exercise intervention based on wearable devices of wearable or body-attached such as bands and watches. For exercise intervention using converged devices that can be enjoyed by the elderly with disability, minimize of environmental limitations, and easy to personalize, there is a need for configuration requirements such as easy operation and simple rules of operation, easy device installation and wearing, a trainer who can complement immature device utilization. In order to maintain and improve the daily living performance of the elderly with disabilities who experience a significant decrease in their cognitive and physical functions, it is necessary to use a physical activity game that can be experienced and can be interested in everyday life or a variety of devices to increase the amount of physical activity.