• Journal of Life Science
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• v.32 no.8
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• pp.601-610
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• 2022

P. tenebrifer (PT) belongs to the Diptera order and Stratiomyidae family. Recently, insect industry have been focused as food, animal feed and environmental advantages. γ-aminobutyric acid (GABA) and melatonin have been associated with regulating sleep and depression. GABA is the primary inhibitory neurotransmitter and is synthesized via biotransformation of monosodium glutamate (MSG) to GABA by lactic acid bacteria. In this study, we first used a GABA-enhanced PT extract, wherein GABA was enhanced by feeding MSG to PT. The underlying mechanisms preventing stress and insomnia were investigated in a corticosterone (CORT)-induced endoplasmic reticulum (ER) stress and chronic restraint stress (CRS)-exposed mouse model, as well as in pentobarbital (45 mg/kg)-induced sleep behaviors in mice. In the present study, the GABA peak was detected in high-performance liquid chromatography-evaporative light scattering detector (HPLC-ELSD) analysis and showed in Ptecticus tenebrifer water extract (PTW) but not in non-PTW extract. The results showed that PTW and Ptecticus tenebrifer with 70% ethanol extract (PTE) exerted neuroprotective effects by protecting against CORT-induced downregulation of phosphorylated extracellular signal-regulated kinase 1/2 (ERK1/2) and cAMP-response element binding protein (CREB) expression. In addition, PTW (300 mg/kg) significantly reduced CORT levels in CRS-exposed mice. Furthermore, PTW (100 and 300 mg/kg) significantly reduced sleep latency and increased total sleep duration in pentobarbital (45 mg/kg)-induced sleeping behaviors, which was related to serum melatonin levels. In conclusion, our results suggest that PTW exerts anti-stress and sleep-enhancing effects by regulating serum CORT and melatonin levels.

• Journal of Life Science
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• v.26 no.7
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• pp.772-781
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• 2016

Dung beetle (Catharsius molossus, CA) is a well-known group of insects thanks to their exploitation of animal feces, a behavioral trait with a global impact on earth′s ecosystems. This study was conducted to investigate the effect of CA extract on a high-fat diet in SD rats. Male rats were divided into 5 groups. Animals were fed on a high-fat diet for seven weeks before and dung beetle extract for a month during the administration. Weight gain was decreased in ethanol extract from CA group. Administration of CA extract reduced the organ weight of testis and kidney, and adipose tissue weight. Lipid oxidative stress was evaluated measuring malondialdehyde level in liver. There were no significant differences in groups. Protein oxidative stress was evaluated measuring protein carbonyl content in blood. The protein carbonyl in blood was significantly decreased in ethanol and acetone extracted dung beetle groups (p<0.05). Meanwhile, the protein carbonyl in hepatocyte was not significant among the groups. Fibronectin and laminin by using D-HUVEC cell in vitro were measured by ELISA assay. There was significance in CA extract. The level of IL-10, IL-1β, VEGF, eNOS was evaluated by ELISA. There was significance in IL-10 compared to control (p<0.05). SOD and GPx tended to increase by CA extract. Furthermore, CAT was increased significantly by CA extract (p<0.05). After administration of CA extracts the composition of saturated fatty acid in adipose tissue tend to decrease, while unsaturated fatty acid increases. In conclusion, dung beetle had anti-hyperglycemia effects of oxidative stress and antioxidant activity.

• Asian Journal of Turfgrass Science
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• v.25 no.2
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• pp.125-132
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• 2011

Drought is a major limiting factor in turfgrass management. Turfgrass responses to water deficit depend on the amount and the rate of water loss as well as the duration of the stress condition. This review paper was designed to understand responses such as photosynthesis, canopy spectral reflectance, plant cell, root, hormone and protein alteration when turfgrass got drought stress. Furthermore, mechanisms to recover from drought conditions were reviewed in detail. However, there are still many questions regarding plant adaptation to water deficit. It is not clear that the mechanism by which plants detect water deficit and transfer that signal into adaptive responses. Turfgrass research should focus on the best management practices such as how to enhance the ability of self-defense mechanism through understanding plant responses by environmental stress.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.385-385
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• 2023

우리나라의 경우 여름철에 강우가 집중되는 특성 및 기후변동을 체감하고 있는 현 시점에서 수자원 시스템을 효과적으로 관리하는 것은 점차 중요해지고 있다. 그러나 IPCC의 미래 기후변화 예측 시나리오는 특정 복사강제력에 기반을 하기에 그 자체만으로도 불확실성이 존재하며, 전 지구적 모형을 활용하는 점에서 우리나라 기후변화 예측 정확성이 저하될 가능성이 있다. 장래 수자원 공급의 의사결정 객관성 및 체계를 확보하고 위에 제시된 단점을 보완하기 위하여, 본 연구에서는 Decision-Scaling을 적용하여 댐 이수안전도를 분석하였다. 연구지역은 충주, 용담, 합천, 섬진강댐을 선정하였다. 기후스트레스 시나리오는 총 91개(순위 기반 강우 스트레스 시나리오 13개 및 0℃에서 6℃까지의 7개 온도 스트레스 시나리오)를 1995년부터 2014년까지 관측된 자료를 바탕으로 구축하였다. 수문모형(IHACRES)과 저수지모형(HEC-ResSim)을 결합하여 이수안전도 분석 모형을 개발하였다. 모형의 검정은 과거 댐 유입량과 비교하였으며, 개발된 모형은 매우 높은 정확도(R²≥0.81)를 보여, 과거 사상에 대한 모의가 가능한 것으로 평가 되었다. 본 연구의 결과로 여름철 강우 변동이 온도와 비교하여 용수공급에 더 큰 영향을 주는 것으로 평가 되었다. (i) 강우와 온도가 동시에 변화하는 시나리오와, (ii) 개별적으로 변화하는 시나리오에 대한 이수안전도의 합과 비교하여, (i)의 경우가 이수안전도에 더 큰 영향 주는 것으로 평가되었다. 이러한 결과는 여름철 강수량의 감소와 증가로 인해 각각 물과 에너지가 제한된 실제증발산이 발생한 것으로 사료된다. 본 연구의 결과는 미래를 포함한 기후 스트레스 발생 시 효율적인 댐 관리 및 운영을 위한 의사결정에 활용 될 수 있을 것으로 판단된다.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.8
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• pp.285-291
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• 2013

In this paper, MOS-Capacitor and MOSFET devices with a Low Level Leakage Current of oxide thickness, channel width and length respectively were to investigate the reliability characterizations mechanism of ultra thin gate oxide films. These stress induced leakage current means leakage current caused by stress voltage. The low level leakage current in stress and transient current of thin silicon oxide films during and after low voltage has been studied from strss bias condition respectively. The stress channel currents through an oxide measured during application of constant gate voltage and the transient channel currents through the oxide measured after application of constant gate voltage. The study have been the determination of the physical processes taking place in the oxides during the low level leakage current in stress and transient current by stress bias and the use of the knowledge of the physical processes for driving operation reliability.

• KAPE Magazine
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• s.129
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• pp.10-10
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• 2007

• Magazine of the Korea Concrete Institute
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• v.4 no.4
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• pp.23-39
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• 1992

• KOREAN POULTRY JOURNAL
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• v.44 no.7
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• pp.112-115
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• 2012

• Magazine of the Korea Concrete Institute
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• v.16 no.1 s.78
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• pp.57-64
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• 2004

• Journal of the Korea institute for structural maintenance and inspection
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• v.16 no.1
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• pp.78-88
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• 2012

Although structural concrete is well known for its good economic efficiency, it has limits of structural performance due to the low tensile strength, for which new structural members utilizing various concrete composite materials have been developed. Steel Fiber-Reinforced Concrete(SFRC) has great tensile strength, which is the one of the excellent composite material to complement the weakness of concrete, and it is also considered as a good alternative to prevent the explosive failure of high strength concrete under fire. Also, prestressed concrete members are of great advantages to long span structures and have greater shear strength compared to conventional reinforced concrete members. In this research, thus, a total of 22 direct shear test specimens were fabricated and tested to understand the shear behavior of Steel Fiber-Reinforced Prestressed Concrete(SFR-PSC) members, in which SFRC members combined with prestressing method. Based on the test results, the constitutive equations of shear behavior at crack interfaces were proposed, which provided good estimation on the shear behavior of the SFR-PSC direct shear test specimens.