• Title/Summary/Keyword: 무작위 실험연구

Search Result 616, Processing Time 0.03 seconds

Prediction of Wave Breaking Using Machine Learning Open Source Platform (머신러닝 오픈소스 플랫폼을 활용한 쇄파 예측)

  • Lee, Kwang-Ho;Kim, Tag-Gyeom;Kim, Do-Sam
    • Journal of Korean Society of Coastal and Ocean Engineers
    • /
    • v.32 no.4
    • /
    • pp.262-272
    • /
    • 2020
  • A large number of studies on wave breaking have been carried out, and many experimental data have been documented. Moreover, on the basis of various experimental data set, many empirical or semi-empirical formulas based primarily on regression analysis have been proposed to quantitatively estimate wave breaking for engineering applications. However, wave breaking has an inherent variability, which imply that a linear statistical approach such as linear regression analysis might be inadequate. This study presents an alternative nonlinear method using an neural network, one of the machine learning methods, to estimate breaking wave height and breaking depth. The neural network is modeled using Tensorflow, a machine learning open source platform distributed by Google. The neural network is trained by randomly selecting the collected experimental data, and the trained neural network is evaluated using data not used for learning process. The results for wave breaking height and depth predicted by fully trained neural network are more accurate than those obtained by existing empirical formulas. These results show that neural network is an useful tool for the prediction of wave breaking.

Opuntia humifusa Supplementation Reduces Fat Weight by Increasing PPAR-γ and PGC-1α Protein Expression in the Skeletal Muscle of Rats (손바닥선인장 보충이 고지방식이 흰쥐 골격근의 PPAR-γ 와 PGC-1α 단백질 발현 증가에 미치는 영향)

  • Kwon, Daekeun;Kang, Junyong;Kim, Jaeseung;Song, Youngju
    • Journal of Life Science
    • /
    • v.24 no.1
    • /
    • pp.67-73
    • /
    • 2014
  • This study was conducted to investigate the effects of supplementation with Opuntia humifusa on the expression of peroxisome proliferator-activated receptor-delta (PPAR-${\delta}$), peroxisome proliferator-activated receptor-gamma (PPAR-${\gamma}$) and peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-$1{\alpha}$) in the skeletal muscle of rats fed a high-fat diet. Sixteen Sprague-Dawley male rats at 6 weeks of age were randomly divided into 2 groups: a control diet group (CG, n=8) and an experimental diet group (EG, n=8). The rats were fed a high-fat diet (CG) or a high-fat diet supplemented with 5% O. humifusa (EG) for 8 weeks. The results showed that the abdominal fat pad and epididymal fat pad weights were significantly lower in the EG than in the CG (p<0.01). In the blood, serum glucose, triglycerides, and total cholesterol in the EG group were lower than in the CG (p<0.01). The expression of PPAR-${\gamma}$ and PGC-$1{\alpha}$ protein in the skeletal muscle of the EG was increased compared with that of the CG (p<0.05). These results indicate that 8 weeks of O. humifusa supplementation lowers serum glucose and triglyceride levels and suppresses weight gain by reducing fat weight through an increase in the expression of PPAR-${\gamma}$ and PGC-$1{\alpha}$ in the muscle tissue of rats.

Comparative study on the apical sealing ability according to the obturation techniques (근관충전방법에 따른 치근단부 폐쇄능에 대한 비교연구)

  • Hwang, Ho-Keel;Park, Sun-Hee;Lee, Yeon-Jae
    • Restorative Dentistry and Endodontics
    • /
    • v.27 no.3
    • /
    • pp.290-298
    • /
    • 2002
  • 3차원적으로 잘 충전된 근관은 치근단 누출과 재감염을 방지하며, 조직이 잘 치유될 수 있는 생물학적 환경을 제공해준다. 이 때문에 근관계의 완전한 충전은 근관치료의 중요한 목표 중의 하나이다. 본 연구의 목적은 4가지 방법으로 근관충전 후 디지털 방사선 사진을 촬영하여 근관충전의 질을 평가하고 투명표본을 제작하여 색소침투범위를 측정함으로써, 근관충전방법에 따른 치근단부 폐쇄능을 비교 평가하고자 하는 것이다. 직선형의 단근관을 갖는 80개의 전치를 선택하여 ProFile$^{\circledR}$ 니켈-티타늄 회전식 기구를 사용하여 근관을 성형한 후 무작위로 20개씩 4군으로 나누었다. 사용된 근관충전법은 다음과 같다:MicroSeal$^{\circledR}$(Group A), Thermafil$^{\circledR}$(Group B), Continuous wave 충전법(Group C), 측방가압충전법(Group D), 각 군에서 10개 치아는 Sealapex를, 나머지 10개 치아는 AH26$^{\circledR}$을 충전용 시멘트로 사용하였다. 근관충전이 끝난 치아는 충전의 질과 길이를 평가하기 위해, 근원심과 협설방향으로 디지털 방사선 사진을 이용하여 촬영하였다. 각 치아의 치근단부 2mm를 제외한 나머지 부위는 두겹의 nail varnish를 바르고, 2% methlylene blue용액에 48시간동안 침잠시켰다. 흐르는 물에 깨끗이 세척한 후, 투명치아를 만들었다. 선상의 색소침투를 관찰하고 치관측 최대깊이를 입체현미경하에서 40배율로 평가하여 다음과 같은 결과를 얻었다. 1. 충전방법에 따른 근단부 폐쇄효과를 비교시, 실험군 모두 비교적 양호한 근단부 폐쇄효과를 보였고 통계학적으로 유의성이 없었다. 2. 충전용 시멘트에 따른 근단부 폐쇄효과를 비교시, AH26$^{\circledR}$을 사용한 군에서 Sealapex를 사용한 군보다 더 적은 색소침 투를 나타냈다(p<0.05). MicroSeal$^{\circledR}$을 이용한 실험 1군내에서 AH26$^{\circledR}$을 사용하였을 때 미세누출이 더 적었고(p<0.05), 다른 군내에서는 통계학적으로 유의성이 없었다. 3. 근단부 충전상태에 따른 미세누출 비교시, 저충전, 과충전과 색소침투간에는 상관관계가 없었다. 4.충전방법에 따른 근단부 충전상태 평가시, Thermafil$^{\circledR}$을 이용한 실험 2군에서 과충전이 많이 나타났다(p<0.05). 이상의 결과로, 기존의 측방가압법 및 여러 열가소성 충전법이 유사한 근단부 폐쇄효과를 나타낸 바, 방법에 따른 술자의 숙련도, 충전시간, 재근관치료의 편이성 등을 고려하여 근관충전방법을 선택하는 것이 합리적일 것이라고 사료된다.

Effects of Korean Computer-Based Cognitive Rehabilitation Program(CoTras) on Frontal-Executive Functions in Patients with Traumatic Brain Injury (한국형 전산화 인지재활프로그램(CoTras)이 외상성 뇌손상 환자의 전두엽-집행기능에 미치는 영향)

  • Han, Seung-Hyup;Jo, Eun-Ju;Noh, Dong-hee;Kam, Kyung-Yoon
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.16 no.5
    • /
    • pp.3344-3352
    • /
    • 2015
  • The purpose of this study is to investigate the effects of Korean computer-based cognitive rehabilitation program (CoTras) on frontal-executive functions in patients with traumatic brain injury (TBI). This study was performed at C hospital in Changwon, Gyeongsangnam-do, Korea from August 2013 to March 2014. Ten patients with TBI were randomly divided into two groups. The experimental group had been given CoTras once a day, five times a week for four weeks, whereas the control group had performed self-cognitive training under the same conditions. To verify the effect of intervention, the following executive function measures were used: Korean Montreal Cognitive Assessment (K-MoCA), Executive Clock Drawing Test (ECDT), Trail Making Test (TMT), Rey-Complex Figure Test (RCFT). Intervention group showed significant increase in K-MoCA, TMT, RCFT-delayed recall (p<.05). However, control group showed no significant change in any test. There was significant difference of changed scores (post test-pre test) between two groups in K-MoCA, TMT and RCFT-delayed recall (p<.05). This study showed that CoTras is effective to improve frontal-executive functions in patients with traumatic brain injury.

Effect of Green Tea and Coffee Drinking after Meal on the Postprandial Fall of Blood Pressure in Elderly Person with Postprandial Hypotension (식후저혈압 노인에서 식후의 녹차와 커피 섭취가 혈압하강에 미치는 효과)

  • Son, Jung Tae
    • 한국노년학
    • /
    • v.36 no.4
    • /
    • pp.1141-1155
    • /
    • 2016
  • The purpose of this study was to compare the preventive effects of green tea and coffee drinking on postprandial hypotension in the elderly. A total of 30 women ($81.2{\pm}6.8years$) who had experience of postprandial hypotension participated 3 interventions by random order allocation. During the experimental interventions, each participant had a cup of instant coffee (60mg caffeine), or green tea (15.8mg caffeine) after lunch, and control group had only their lunch. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured with 15 minute interval from 30 minutes before the meal to 120 minutes after the meal. The preprandial SBP and DBP were not significantly different between three groups. Postprandial SBP reduction measured at the 1 hour after meal was significantly smaller in coffee group compared to the control group, whereas green tea group was not ($-15.1{\pm}17.9mmHg$ vs $-13.4{\pm}22.4mmHg$ vs. $-4.1{\pm}18.6mmHg$ for control, green tea, and coffee group, respectively, p=.032). Likewise, DBP decrement at the 1 hour after meal was significantly smaller in coffee than control group ($-12.8{\pm}13.0mmHg$ vs $-6.9{\pm}16.6mmHg$ vs $-0.8{\pm}13.4mmHg$ respectively, p=.033). The HR response of the three groups were not significantly different throughout the intervention. Coffee drinking was potentially beneficial for preventing postprandial hypotension and resultant falling event.

Effect of Oral Motor Facilitation Technique on Oral Motor Function in Stroke Patients (구강운동촉진기술(Oral Motor Facilitation Technique)이 뇌졸중 환자의 구강운동기능에 미치는 효과)

  • Son, Yeong Soo;Min, Kyoung Chul;Woo, Hee-Soon
    • Therapeutic Science for Rehabilitation
    • /
    • v.12 no.4
    • /
    • pp.135-151
    • /
    • 2023
  • Objective : This study was conducted to confirm the effect of the oral motor facilitation technique (OMFT) on oral motor function in stroke patients. Methods : This study was conducted on 72 stroke patients with dysphagia were included. Thirty-six patients were randomly assigned to the experimental and control groups were randomly classified into 36 patients each using a random table, and a two-group pre-post test was designed. The experimental group underwent OMFT, and the control group underwent traditional dysphagia therapy for 30 min, once a day, 5 times a week for 4 weeks, for a total of 20 sessions. The Comprehensive Orofacial Function Scale (COFFS) was used to evaluate oral motor function. Repeated-measures analysis of variance (ANOVA) was performed to confirm the effect of the period, and an independent t-test was performed to analyze the difference in change between the two groups. Results : Total COFFS scores improved in both groups. The experimental group showed significant changes in mandibular and lip movements, cheek blows, and tongue movements. In addition, there were significant differences depending on the intervention period in terms of masticatory distribution, food spillage, swallowing of solid and liquid foods, and voice changes. There were significant differences in the mandibular opening and closing categories between the two groups. Conclusion : OMFT is effective in improving oral motor function in stroke patients with dysphagia and can be used as basic evidence in clinical practice.

Effects of Aroma Neck and Shoulder Massage and Red LED irradiation on cutaneous microcirculation in the neck area (아로마 목·어깨 마사지와 Red LED 조사가 목 피부 미세혈류에 미치는 영향)

  • Yang Yang;Seunghee Bae
    • Journal of the Korean Applied Science and Technology
    • /
    • v.41 no.2
    • /
    • pp.393-405
    • /
    • 2024
  • This study investigates the effects of aroma neck and shoulder massage and Red LED irradiation on cutaneous microcirculation in the neck area. In this study, 30 women aged 20 to 60 were randomly assigned to three experimental groups. Group A (n=10) received Red LED irradiation after aroma neck and shoulder massage, while Group B (n=10) rested for 15 minutes after aroma neck and shoulder massage. Group C (n=10) only received Red LED irradiation. The results showed significant main effects of time between the baseline and post-treatment measurements in Groups A and B (F = 29.883, p < 0.001, 𝜂2 = 0.624), however, the main effects of the groups were not significant (F = 0.202, p = 0.659, 𝜂2 = 0.011), but there was a significant interaction between group and time (F = 8.452, p = 0.001, 𝜂2 = 0.320). There were no significant statistical differences in cutaneous microcirculation in the neck area after treatment in Group C (p > 0.05, Cohen's d = 0.202). In conclusion, Red LED treatment demonstrates limited effects on cutaneous microcirculation in the neck area, differentiating with the results of Groups A and B. Specifically, the combined effect of aroma neck and shoulder massage and Red LED treatment in Group A was not significant.

Evaluation of Leather Meal and Meat and Bone Meal as the Fish Meal Replacer in Israeli Carp Diets (잉어사료에 있어서 피혁분과 육골분의 어분대체원으로서의 평가)

  • 배승철;장혜경;김경희
    • Journal of Aquaculture
    • /
    • v.10 no.2
    • /
    • pp.153-161
    • /
    • 1997
  • This study was conducted to evaluate the possible utilization and the replacing range of leather meal (LM) or meat and bone meal (MBM) as a fish meal replacer for the dietary animal protein source of growing israeli carp, Cyprinus carpio. Five different diets were formulated on isonitrigenous and isocaloric basis of 38.5% curde protein and 15.3 KJ/g diet. Percentage of the graded levels of replacement of white fish meal (WFM) by LM/MBM on the basis of crude protein were at follows : diet 1, 100% WFM (control) ; diet 2, 75% WFM+25% LM ; diet 3, 50% LM ; diet 4, 75% WFM+25% MBM ; diet 5, 50 WFM+50% MBM and LM or MBM, and approximately 64.5% of plant protein. After one week of conditioning period, fish averaging 10g were divided into five groups and fed one of the experimental diets for 12 weeks. In the first and the second 4 weeks of feeding trials, there were no significant differences in weight gain between two groups of fish fed diet 1 (control) and 2 (P>0.05), while fish fed diet 3, 4 and 5 had a significantly lower body weight gain than fish fed diet 1 (P<0.05). In contrast to those two periods, all diet groups were not significantly different compared to diet 1 in body weight gain during the third 4 weeks of feeding trial (P<0.05). These results indicated that LM and MBM could be used as a fishmeal replacer up to 50% in growing israeli carp.

  • PDF

The effect of balance improvement on balance training with visual feedback and somatosensory (시각 되먹임을 이용한 균형 훈련과 체성감각을 이용한 균형훈련이 균형 향상에 미치는 영향)

  • Lee, Jun-cheol
    • The Journal of the Convergence on Culture Technology
    • /
    • v.6 no.4
    • /
    • pp.677-684
    • /
    • 2020
  • Our country is already in the aging corner and fall down is the elderly personal, social and economic problems are causing. therefore, executed this study for inquiring into an athletic effect for the balance ability increase that was a main variable of an fall down. The purpose of this study, to find the effect of balance training using visual feedback and somatosensory. Experimental group divided the three groups, objects measured balance ability of each experimental groups before experiment, the balance exercise group used visual feedback by Nintendo Wii(company - model), the balance exercise group used visual and TOGU, the balance exercise group used blind and TOGU. 4 experimental of each groups measured MFT and EMG value after training. having rest time, 4 experimental of each groups measured MFT and EMG value after training used balance pad. MFT - visual feedback with somatosensory training is most efficient but, indifferent both balance training with visual feedback and balance training with somatosensory. EMG - training with somatosensory is more efficient than training with visual feedback. Conclusion : in the process of improving equilibrium ability of patient who is lack of balance ability, somatosensory training is effective to correct different of left, right and frequency of left, right. visual feedback is the most effective way to improve dynamic balance sensory, so parallel of these two practice is thought to be the most effective.

The Influence of Cranial Cervical Ganglion Block in Beagle Dogs with Normal Intraocular Pressure (비글견에서 앞쪽목신경절 차단술이 정상 안압에 미치는 영향)

  • Park, Woo-Dae;Bae, Chun-Sik;Kim, Hwi-Yool
    • Journal of Life Science
    • /
    • v.17 no.11
    • /
    • pp.1472-1476
    • /
    • 2007
  • This study was performed to observe changes of the intraocular pressure following cranial cervical ganglion block with the four different concentrations of lidocaine in beagle dogs with the normal intraocular pressure. We performed by the crossover test in ten beagle dogs divided into four groups, which were 2%, 1%, 0.5% and 0.25% lidocaine group. All experimental dogs received each four times cranial cervical ganglion block using 2 ml of lidocaine with the four different concentrations. The blocks were separately done at a week intervals in random order. Horner#s syndrome was observed in all groups. The intraocular pressure in the blocked side was significantly increased to 5 min in the 1% lidocaine group compared to the baseline (p<0.05). The intraocular pressure of 2% and 1% lidocaine groups were decreased between 25 and 45 min following cranial cervical ganglion block, while those of 0.5% and 0.25% lidocaine groups were unchanged. In conclusion, these results suggest that cranial cervical ganglion block affect on the change of intraocular pressure and 0.5% and 0.25% lidocaine are inadequate concentrations for the change of intraocular pressure in the dog with normal intraocular pressure.