• Title/Summary/Keyword: 모체효과

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SNP-based and pedigree-based estimation of heritability and maternal effect for body weight traits in an F2 intercross between Landrace and Jeju native black pigs (제주재래흑돼지와 랜드레이스 F2 교배축군의 생체중에 대한 유전체와 가계도 기반의 유전력 및 모체효과 추정)

  • Park, Hee-Bok;Han, Sang-Hyun;Lee, Jae-Bong;Kim, Sang-Geum;Kang, Yong-Jun;Shin, Hyun-Sook;Shin, Sang-Min;Kim, Ji-Hyang;Son, Jun-Kyu;Baek, Kwang-Soo;Cho, Sang-Rae;Cho, In-Cheol
    • Journal of Embryo Transfer
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    • v.31 no.3
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    • pp.243-247
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    • 2016
  • Growth traits, such as body weight, directly influence productivity and economic efficiency in the swine industry. In this study, we estimate heritability for body weight traits usinginformation from pedigree and genome-wide single nucleotide polymorphism (SNP) chip data. Four body weight phenotypes were measured in 1,105 $F_2$ progeny from an intercross between Landrace and Jeju native black pigs. All experimental animals were subjected to genotypic analysis using PorcineSNP60K BeadChip platform, and 39,992 autosomal SNP markers filtered by quality control criteria were used to construct genomic relationship matrix for heritability estimation. Restricted maximum likelihood estimates of heritability were obtained using both genomic- and pedigree- relationship matrix in a linear mixed model. The heritability estimates using SNP information were smaller (0.36-0.55) than those which were estimated using pedigree information (0.62-0.97). To investigate effect of common environment, such as maternal effect, on heritability estimation, we included maternal effect as an additional random effect term in the linear mixed model analysis. We detected substantial proportions of phenotypic variance components were explained by maternal effect. And the heritability estimates using both pedigree and SNP information were decreased. Therefore, heritability estimates must be interpreted cautiously when there are obvious common environmental variance components.

Time Trends in Estimates of Genetic Parameters in a Population of Layer Breeders (난용종계 집단에서의 선발에 의한 유전모수 변화 양상)

  • 최연호;오봉국
    • Korean Journal of Poultry Science
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    • v.17 no.4
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    • pp.255-268
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    • 1990
  • This study was carried out to investigate the time-trends of genetic parameters of the dosed flock population which selected for improving egg production. Data for two layer pure lines, Line-W (Single Comb White Leghorn) and Line-B (brown layer) which have been maintained at the Mani Breeding Farm were collected from 1980 to 1985 during 5 generations. The effective number of parents per generation ranged from 148 to 366 in Line-W and 85 to 355 in Line-B, and the cumulative expected inbreeding coefficients during 5 generations of selection were 15% and 1.6%. So inbreeding could not be considered a critical factor on estimating the genetic parameters, heritabilities and genetic correlations Heritabilities of EN 300 and EN 400, primary two selected traits were significantly decreased during 5 generations but the estimates of the other 03its not showed the consistent decreasing pattern significantly. No time trends of probable consequence were evident in the genetic correlation coefficients of the traits studied. The reason for that situation was attributed to the fact that selection was conducted for multiple objectives and the relative importance of selection for the studied traits were not consistent by generations.

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The chemical speciation and analysis of trace elements in sediment with neutron activation analytical method(NAA) and atomic mass spectrometry (중성자 방사화분석법과 원자질량분석법을 이용한 침전물 시료속에 존재하는 미량원소들의 화학종 분류 및 분석)

  • Nam, Sang-Ho;Kim, Jae-Jin;Chung, Yong-Sam;Kim, Sun-Ha
    • Analytical Science and Technology
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    • v.16 no.5
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    • pp.358-367
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    • 2003
  • In this research, first of all, the analytical methods for the determination of major elements in sediment have been developed with ICP-MS (Inductively Coupled Plasma Mass Spectrometry). The analytical results of major elements (Al, Ca, K, Fe, Mg) with Cool ICP-MS were much better than those with normal ICP-MS. The analytical results were compared with those of NAA (Neutron Activation Analysis). NAA were a little superior to ICP-MS for the determination of major elements in sediment as a non-destructive trace analytical method. The analytical methods for the determination of minor elements (Cr, Ce, U, Co, Pb, As, Se) have been also developed with ICP-MS. The analytical results by standard calibration curve with ICP-MS were not accurate due to the matrix interferences. Thus, the internal standard method was applied, then the analytical results for minor elements with ICP-MS were greatly improved. The analytical results obtained by ICP-MS were compared with those obtained by NAA. It showed that the two analytical methods have great capabilities for the determination of minor elements in sediments. Accordingly, the NAA will play an important role in analysis of environment sample with complex matrix. ICP-MS also will play an important role because it has a great capability for the determination of Pb that could not be determined by NAA.

Development Toxicity Evaluation (랫드에서 표준 및 사료제한 시험에 의한 fluoroquinolone 항균제 DW-116의 발생독성평가)

  • 김종춘;윤효인;이희복;한상섭;정문구
    • Journal of Life Science
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    • v.11 no.5
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    • pp.447-456
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    • 2001
  • We have recently demonstrated that the fluoroquinolone antibacterial DW-116 caused a significant developmental toxicity in rats. The present study was conducted to determine whether the development toxicity induced by DW-116 treatment was the result of malnutrition fro reduced food intake or the direct effects of test chemical on conceptuses. The test chemical was administered by gavage to pregnant rats from gestational days 6 through 16 at dose levels of 0 and 500 mg/kg/day. A pair-feeding study was also performed in which the pregnant rats received the same amount of diet consumed by the DW-116-treated pregnant rats. All dams were subjected to caesarean section on day 20 of gestation and their fetuses were examined for examined for external, visceral, and skeletal abnormalities. In this treatment group, the maternal toxicities included increased abnormal clinical signs, decreased maternal body weight, suppressed body weight gain during treatment and posttreatment periods, and reduced food intake. The significant developmental toxicities included increased fetal deaths, decreased live fetuses, reduced fetal body weight and placental weight, increased incidence of fetal abnormalities, and increased fetal ossification delay. In this pair-fed group, however, slight maternal toxicities including decreased body weight and suppressed body weight gain during treatment period were observed in comparison with the control group, and minimal development toxicities including reduced fetal and placental weights and increased fetal ossification delay were found. The number of fetal deaths and live fetuses, and the incidences of malformed fetuses and litters with affected fetuses were comparable to the control values. Based on the results, it could be concluded that the development toxicity observed in the treatment group is attributable to the direct effects of Dw-116 treatment, but not to the maternal malnutrition from reduced food consumption during pregnancy.

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Performance Analysis of MC/DS-CDMA System with Smart Antenna (기지국용 스마트 안테나를 적용한 MC/DS-CDMA 시스템의 성능분석)

  • 박인규;김백현;신승훈;곽경섭
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.4B
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    • pp.291-297
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    • 2002
  • Due to the increasing demand for high data multimedia service, there has been progressing study of adaptive smart antenna to increase both the performance and capacity using limited wireless resource. IS-95 scheme in the origin of cdma2000 of IMT-2000 standard uses signals of spreading and Walsh-Orthogonal Modulation in reverse link. But, in the case of reverse lint there exists difficulty in synchronous of signals transmitted from users. Therefore, orthogonality between users is not satisfied. So, asynchronous MC-CDMA scheme may yield low performance. In this paper, MC/DS-CDMA scheme to reverse link transmission in adaptive array antenna environment is proposed for spreading the S/P-converted data streams using a given spreading code. Due to frequency diversity effect, simulation results show that the proposed system provides improved BER performance and narrow band interference supple psi on.

A Study on the variations of mechanical and electrical property of epoxy composites due to boiling absorption (비등흡수에 의한 에폭시 복합재료의 기계적 특성 및 전기적 특성 변화에 관한 연구)

  • 이덕진;신성권;김재환
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.14 no.1
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    • pp.53-58
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    • 2000
  • In this paper, the variable mechanical strength and dielectric breakdown strength of epoxy composites were measured at boiling absorption condition in order to observe the influences of moisture in out door use. Also, in order to improve water resistance of matrix resin, IPN(interpenetrating polymer network) method which had been already reported, was introduced and the influence was investigated. As Adding filter(SiO2) classified by o[phr], 50[phr] and 100[phr] to two kinds of matrix resin, six kinds of specimens were manufactured. As a result, it was confirmed that the moisture absorption rate was increased and mechanical strength and dielectric breakdown strength were degraded with boiling time and filler content increasing. On the other hand, it was confirmed that moisture absorption rates were decreased and the degrading rates of mechanical strength and dielectric breakdown strength were lowered according to improvement of adhesion strength in case of IPN specimens.

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C-and Fe-(Beewax.Polyethylene) PTC Thermistors (C- 및 Fe-(Beewax.Polyethylene) 정특성 감온소자)

  • Lee, Jong-Hyeon;Son, Byeong-Gi;Lee, Jong-Deok
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.13 no.4
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    • pp.6-11
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    • 1976
  • The carbon (the iron) -beewax.polyethylene thermistors have been prepared by heating the well ground mixture of carbon (iron), beewax and polyethylene at 16$0^{\circ}C$ for one hour and by cooling it under pressure of 12kgw/cm2. The resistivity for the former (the latter) increased from 102$\Omega$.cm (104$\Omega$.cw) to 1010$\Omega$.cm(1010$\Omega$.cm) as temperature changed from 2$0^{\circ}C$ to 9$0^{\circ}C$. The resistivity, 102$\Omega$.cm at room temperature for the former, was lower by order Q( two than that for the papostor made by the earlier reporter. The reproducibility, which has been an important Problem for this type of thermistors to be industrialized, was improved by introducing pressure in cooling procedure for both carbon and iron thermistors.

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An Experimental Study on the Flexural Behavior of Pre-loaded RC Beams Strengthened with CFRP-Rod (선하중(先荷重)을 받은 RC보의 CFRP-Rod 휨보강 효과에 대한 실험적 연구)

  • Ye, Sang-Min;Chun, Woo-Chul;Kang, Joo-Won;Park, Sung-Moo
    • Journal of Korean Association for Spatial Structures
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    • v.7 no.1 s.23
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    • pp.79-85
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    • 2007
  • Steel plate bonding method with epoxy is common applied to repair and strengthen RC structures, but Steel is apt to corrode quickly, hard to manufacture and heavy. To overcome these defects, it is carried out research on strengthening RC structures with FRP(Fibre Reinforced Polyrner/Plastic) FRP is generally used in the shape of Plate or Sheet, but it has weak point such as premature failure, difficult work. To cope with these problem, NSMR(Near Surface Mounted Reinforcement) which uses CFRP in the shape of Rod is proposed and carried out active research on strengthening effect of variables such as quantity, anchorage length and space of CFRP-Rod. Strengthening with CFRP-Rod is carried out under loading to some degree in fact, and so the amount of pre-loading is selected as variable in this research. The amount of pre-loading is chosen in proportion to nominal strength of non-strengthened specimen with CFRP-Rod.

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Improvement in Fatigue Durability of RC Beams Strengthened with Carbon Fiber Sheets (탄소섬유시트로 보강된 RC 보의 피로내구성 향상에 관한 연구)

  • Park, Jeong-Yong;Kim, Seong-Do;Jo, Baik-Soon;Kim, In-Tae;Cheung, Jin-Hwan
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.10 no.6
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    • pp.205-212
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    • 2006
  • In recent investigations, reinforced concrete beams strengthened with Carbon Fiber Sheets (CFS) subjected to fatigue loading were reported to be failed at the ends of CFS by its debonding. U-shaped CFS were attached to both ends of the CFS when fatigue tests on strengthened beams were conducted to delay and/or prevent fatigue failures of adhesive interface. The experimental parameters of this study were the usage of anchorage at the ends of CFS, the number of CFS layers, and the applied load levels of 60%~90% of the static ultimate load obtained from the static tests. The failure modes and the load cycle-deflection relations were observed and discussed from the experimental results. Those results also showed that the U-shaped anchoring system changes the fatigue failure modes and influences greatly on the fatigue capacity of the strengthened beams.

An Experimental of RC Beams Strengthened with Pultruded Glass Fiber and Steel strip (통기성 유리섬유-강판 인발성형 스트립으로 보강된 RC보의 실험적 거동분석)

  • Kim, Woonhak;Kang, Seokwon
    • Journal of the Society of Disaster Information
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    • v.9 no.3
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    • pp.315-323
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    • 2013
  • Recently, FRB is being used more as reinforcement of RC beam thanks to its material advantages in construction industry. The external attachment reinforcement of FRP is a construction method with advantages such as high strength, stiffness, excellent durability and construction practicability, despite of its weight. However, the reinforcement has a disadvantage to cause damage on permanent structure as its structure is water-tight by low water permeability reinforcement, preventing water from draining outside. The study attempted flexural failure test for GP of which material properties are equally same as the existing FRP and that with permeability, shows good binding with the concrete structure, durable performance and durability, comparably analyzing the improvement of durability and ductility according to changes of fiber contents of composite strip.