• Title/Summary/Keyword: 모델 이해

Search Result 2,808, Processing Time 0.032 seconds

Differences in fecal and cecal microbiota in C57BL/6J mice fed normal and high fat diet (고지방 식이 조절에 따른 C57BL/6J 마우스의 분변과 맹장에서 나타나는 미생물생태 차이)

  • Lee, Sunwoo;Vineet, Singh;Unno, Tatsuya
    • Journal of Applied Biological Chemistry
    • /
    • v.64 no.4
    • /
    • pp.399-405
    • /
    • 2021
  • A number of studies have been conducted to prevent obesity due to the worldwide increasing rate of obesity and its adverse effects on our health. Recently, a relationship between obesity and gut microbiome has been reported. Fecal and cecal microbiota are generally targeted for examining the gut microbiome during dietary interventions. There is, however, no common understanding on which microbiota and how results elucidated from the data would differ. In this study, we conducted dietary induced obesity study and compared fecal and cecal microbiota affected by dietary interventions. Normal Diet and high fat diet were fed to 6 weeks old mice for 12 weeks, and 16 S rRNA genes amplified from fecal and cecal DNA were sequenced using MiSeq. Our results show that the 𝛼-diversity showed significant differences between the dietary interventions as well as cecal and fecal microbiota. The difference in the taxonomic compositions between cecal and fecal microbiota had become clearer at the family and genus level. At the genus level, Faecalibaculum and Lactobacillus were more abundant in the cecal and fecal microbiota, respectively. In general dietary intervention studies, dietary effects are more significant than type difference. However, the microbiota analysis results should be interpreted carefully, considering both diet and samples (feces/caecum).

Educational Support Activities of Private Organizations to Alleviate the Educational Gap: Focusing on Teach For America in USA and Dream Touch For All in Korea (교육 격차 해소를 위한 민간단체의 교육지원 활동: 미국의 Teach For America와 한국의 Dream Touch For All을 중심으로)

  • Min, Yunkyung;Park, Keunah;Lee, Hae-Nee
    • Korean Journal of Comparative Education
    • /
    • v.28 no.6
    • /
    • pp.85-109
    • /
    • 2018
  • This paper aims to compare the two groups of TFA in U.S. and Dream Touch For All in Korea established with the same goals: 1) goal and core value, 2) qualification and training of teachers, and 3) educational performance. As a result of the analysis, the two groups showed that they focused on the role of teachers to improve the academic achievement of the underprivileged under the goal of solving the inequality of education. However, while TFA in the United States was able to function within public education, Korea's Dream Touch For All played a complementary role in public education. In the case of the United States, it appears to be a 'quasi-open' teacher training system that allows teachers from alternative teacher groups such as TFA to be accepted, while in Korea it shows the character of 'closed teacher training system' to be. For this reason, the two groups showed differences in core value, teacher training, and operating program, and as a result, they also set different educational models.

The Problem of the Repression and the Unconscious in Delueze and Guattari's schizo-analysis (들뢰즈, 가타리의 분열분석에서억압과 무의식의 문제)

  • Yon, Hyo-Sook
    • Journal of Korean Philosophical Society
    • /
    • no.121
    • /
    • pp.93-121
    • /
    • 2018
  • Deleuze and Guattari criticise in Anti-Oedipus theory of desire of Freud and Lacan as the idealist conception of desire as lack(fantasy) and try to search for a possibility of materialistic theory of desire. They criticise that Freud and Lacan trap the desire into the model of oedipal model and cut the flux of Libido of desire. This paper looks out for the different reason for the interpretation between psychoanalysis and schizoanalysis about the desire into the difference of interpretation about the 'repression' and 'the unconscious'. From this first of all, it examines the aspect of repression in Freud and Lacan, and it searchs for the meaning of distinction between 'psychic repression' and 'social repression' according to the interpretation in Deleuze and Guattari. Secondly, Freud and Lacan understand the unconscious as the region drived out by the defense mechanism of the mind activity, or the dimension of the unconscious structured like language. On the contrary, Deleuze and Guattari approach entirely differently interpretation about the unconscious. This paper analyzesespecially the unconscious of orphan, the unconscious productive and the unconscious molecular in the midst of manifold and new interpretation about the unconscious. In conclusion, it shows that the problem of desire and inhibition completely differently can be considered according to the new interpretation about the unconscious. It tries to serarch for the practical adaptability of schizoanalysis in Deleuze and Guattari on the real society.

A Study on Management and Present-Condition of Invasive Alien Species (외래식물 분포 및 관리방안)

  • Park, Sang-Heon;Lee, Hae-Seung
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.19 no.11
    • /
    • pp.488-496
    • /
    • 2018
  • This study examined the Gangwon Province's current implementation of its elimination of invasive plants and explored a plan to effectively manage invasive plants. The percentage of the distribution of the plants was 39.6% for riverside areas, 23.3% for roadside areas, 12.4% for roadside & riverside areas, and 4.6% for areas around farm land and river banks. To ensure the systematic management of invasive plants, the current study suggests a) developing an invasive plants monitoring and management system; b) reinvigorating the participation of residents, private organizations, and military posts; c) planting of native replacement plants and the conversion of the locations as attractions, and d) nurturing the project for using invasive plants. For policy directions to be pursued based on the results of the study, the following are suggested: a) improving laws and systems regarding invasive plants, b) developing a cooperative system for managing invasive plants, c) implementing the training of civilian professionals, d) implementing the elimination of invasive plants, e) developing replacement plants for cities and counties, f) fostering industries that tap into invasive plants, and g) using the Han River Water System Management Fund for funding and greater efficiency.

A Review on Disaster Response through Critical Discourse Analysis of Newspaper Articles - Focused on the November 2017 Pohang Earthquake (신문기사의 비판적 담론분석을 통한 재난대응에 대한 고찰 - 2017년 11월 '포항지진'을 중심으로)

  • Lee, Yeseul;Jeon, HyeSook;Lee, Kwonmin;Min, Baehyun;Choi, Yong-Sang
    • Journal of the Society of Disaster Information
    • /
    • v.15 no.2
    • /
    • pp.223-238
    • /
    • 2019
  • Purpose: This study aims at exploring implications of discourse and social practice produced by various stakeholders in politics, economy and society to provide useful material for effective disaster response in South Korea. Method: Applying the Critical Discourse Analysis model of Fairclough, this study analyzes the newspaper articles of three domestic press companies mainly about the November 2017 Pohang earthquake. Results: As a result, first, the three media companies point out the low effectiveness of disaster response manuals and evacuation training. Second, strengthening shelter services and expanding support for the victims are important for recovery from the earthquake. Third, to prevent the future damages, they suggest the implementation efforts to improve the seismic design and short message service based disaster alert system. Conclusion: Based on the findings, this study suggests to improve the practicality and effectiveness of disaster prevention measures, establish an organic and integrated disaster response system, emphasize the roles and participation of citizens, check the responsibility of experts, and make the media to form sound discourse on disaster response.

Effects of Open Innovation on Export Performance: Moderation of Innovation Speed (개방형 혁신이 수출성과에 미치는 영향: 혁신속도의 조절효과를 중심으로)

  • Roh, Taewoo;Park, Kwangmin;Seo, Jeongeun;Kim, Gyunhwan;Kim, Hwayoung;Kang, Minah
    • Journal of Digital Convergence
    • /
    • v.16 no.12
    • /
    • pp.207-215
    • /
    • 2018
  • This study started from the point that the most important SMEs in the economic growth engine of Korea are prepared to grow through innovation. This study focuses on the fact that existing studies have focused on the open innovation of SMEs has been continued since the external knowledge search became an important concept, but mainly focused on the enterprise performance. The purpose of this study is to examine the moderating effect of innovation speed focusing on exports to Korean SMEs. The hypothesis suggests the depth and breadth of external knowledge search, which is the two methods of open innovation emphasized in the previous studies, and then shows the innovation speed on export performance as a moderating effect. Robust regression analysis was used for the analysis and the sample used for the analysis was valid 1,357 SMEs data. The hypothesis test for the moderation effect was performed by comparing the F-values between models. The proposed hypothesis was adopted and the moderation effect was verified.

A proposal for the classification of Korean taste terms (한국어의 '맛 어휘' 분류 체계)

  • Kim, Hyeong Min
    • 기호학연구
    • /
    • no.56
    • /
    • pp.7-44
    • /
    • 2018
  • The objective of this paper is to propose a classification of Korean taste terms, especially Korean taste adjectives, from the perspective of cognitive science. The classification of Korean taste terms is here grounded in the definition of 'taste sense', 'flavor' and 'taste' which is usually employed in disciplines of cognitive science. There have been a large number of domestic researches in field of taste terms. Accordingly, a lot of research findings on the classification of taste terms have steadily been released showing the differences among researchers. These different classifications are largely based on the fact that researchers have applied their subjective criteria rather than their objective in order to categorize taste terms. According to previous studies, it is well-known that, in everyday usage, the term 'taste' covers a much wider range of qualities than those perceived through the taste receptor cells alone. In addition, we take it for granted that as much as 80~90% of taste comes from olfactory modality. It is also important to note that the texture and temperature of food, the color of food, the sounds of food, and atmospheric cues have an essential effect on taste perception. Many scientists have already pointed out that taste evaluations are influenced by a number of individual and sociocultural factors. Eating and tasting are important parts of our everyday life, so that linguistic approaches to taste perception seem to be of great significance. We can assume that a classification of taste terms from the perspective of cognitive sciences may shed light on the perceptive mechanism through which we perceive taste. It should be noted that this paper is an advanced work prepared for the follow-up study which will try to make a geometric model of word field 'taste terms' existing or probably existing in the mental lexicon of human beings.

Validation of Sea Surface Wind Estimated from KOMPSAT-5 Backscattering Coefficient Data (KOMPSAT-5 후방산란계수 자료로 산출된 해상풍 검증)

  • Jang, Jae-Cheol;Park, Kyung-Ae;Yang, Dochul
    • Korean Journal of Remote Sensing
    • /
    • v.34 no.6_3
    • /
    • pp.1383-1398
    • /
    • 2018
  • Sea surface wind is one of the most fundamental variables for understanding diverse marine phenomena. Although scatterometers have produced global wind field data since the early 1990's, the data has been used limitedly in oceanic applications due to it slow spatial resolution, especially at coastal regions. Synthetic Aperture Radar (SAR) is capable to produce high resolution wind field data. KOMPSAT-5 is the first Korean satellite equipped with X-band SAR instrument and is able to retrieve the sea surface wind. This study presents the validation results of sea surface wind derived from the KOMPSAT-5 backscattering coefficient data for the first time. We collected 18 KOMPSAT-5 ES mode data to produce a matchup database collocated with buoy stations. In order to calculate the accurate wind speed, we preprocessed the SAR data, including land masking, speckle noise reduction, and ship detection, and converted the in-situ wind to 10-m neutral wind as reference wind data using Liu-Katsaros-Businger (LKB) model. The sea surface winds based on XMOD2 show root-mean-square errors of about $2.41-2.74m\;s^{-1}$ depending on backscattering coefficient conversion equations. In-depth analyses on the wind speed errors derived from KOMPSAT-5 backscattering coefficient data reveal the existence of diverse potential error factors such as image quality related to range ambiguity, discrete and discontinuous distribution of incidence angle, change in marine atmospheric environment, impacts on atmospheric gravity waves, ocean wave spectrum, and internal wave.

Aged Doraji (Platycodon grandiflorum) Ameliorates Cyclophosphamide-Induced Immunosuppression in Mice (Cyclophosphamide에 의해 유도된 면역저하 마우스 모델에서 홍도라지 추출물의 면역 기능 조절 효과)

  • Choi, Ji-Hye;Lee, Eun Byeol;Park, Yang-Gyu;Lee, Hye Kyung;Jang, Hwan Hee;Choe, Jeongsook;Hwang, Kyung-A;Park, Shin Young;Hwang, In Guk;Hong, Ha Cheol;Lee, Hae-Jeung;Jeong, Hyun Cheol;Kim, Hyun-Ju;Lee, Sung Hyen
    • Korean Journal of Pharmacognosy
    • /
    • v.50 no.3
    • /
    • pp.219-225
    • /
    • 2019
  • This study was done to examine immunomodulative effects of aged doraji (AD) in the immune-suppressed mice induced by cyclophosphamide. The immune-stimulating effects of ethanol AD extract in in vivo at 75 and 150 mg/kg body weight (BW) for AD and 2AD groups were evaluated and compared to the normal doraji group (2ND, 150 mg/kg BW) treated with a doraji without aging process. After the 10 days of oral supplement, body and immune related organ weights, serum immunoglobulin G (IgG) and cytokines levels, splenocytes proliferation rate, and splenic NK cell activity were measured as immune-related biomarkers. Body weight and serum IgG level increased in the 2AD group. But, the serum Th2 cytokine (IL-6, $TNF-{\alpha}$) levels were lower in the AD and 2AD groups, respectively. Splenic T cell and B cell proliferation and NK cell activity increased in the doraji groups and the significant increases were found only in the 2AD group. Thus, the aged doraji extract may affect body weight, serum IgG level, splenocytes proliferation, and splenic NK cell activity, and normalize the Th2 cytokine levels in the immune-suppressed mice. The results suggest that the aged doraji improves effectively immune system rather than the normal one.

Development Status of Technology Demonstration Model for Staged Combustion Cycle Engine (다단연소사이클 엔진 기술검증시제 개발 현황)

  • Kim, Chaehyoung;Lee, Jungho;Woo, Seongphil;So, Younseok;Yi, SeungJae;Lee, Kwang-Jin;Cho, Namkyung;Han, Yeoungmin;Kim, Jin-han
    • Journal of the Korean Society of Propulsion Engineers
    • /
    • v.23 no.4
    • /
    • pp.104-111
    • /
    • 2019
  • Staged combustion cycle engines exhibit higher combustion performance compared with open cycle engines with a gas generator. An advanced research of the staged combustion cycle engine is going on for the next program following the KSLV-II program. Various experiments have been carried out for the technology demonstration model, TDM0A and TDM0B. The experiments on the combustion performance are aimed to understand the engine start condition and combustion characteristics. They also aim to develop the oxidizer-rich pre-burner and the combustor of the staged combustion cycle engine. The engine-shaped model, TDM1A is fabricated based on the experimental data. The combustion experiment of the TDM1A shows that the combustion pressure of the combustor is approximately 91 bar and the turbine rotation is approximately 28,00 rpm. The result is stable and satisfies the development requirements. The present paper reports on the development process and characteristics of engine models from TDM0A to TDM1A.