• Journal of Navigation and Port Research
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• v.26 no.1
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• pp.137-145
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• 2002

Water flow simulations for environmental problems often require local detailed analyses for better understanding and accurate prediction of the fate of pollutant in water bodies. This study deals with the development and application of a two-dimensional flow an dispersion model to the coastal water area to find out possible changes due to the wide port development plan. As far as the spatial discretization is concerned, the finite element method is attractive because of its flexibility and ability to naturally treat complex coastal geometries. The model uses finite element theory and the Galerkin weighted-residual approach as its basis. Developed model is applied to the Busan New harbor Construction site. Results from the model were compared with the measured water level and flows in four stations. The flow pattern by the model shows to be similar to the observed data away from the construction site where the flow is not affected. From the simulation results, it is concluded that the model may be useful for numerous other studies for planning and management purposes, especially flow and pollution dispersion in the coastal water bodies where the flow is so complicated.

• The KIPS Transactions:PartD
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• v.10D no.1
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• pp.85-100
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• 2003

Today's computing system has expanded its application to business trade and distributed work transactions using the Internet. As the demand for more flexible, adaptable, extensible, and robust web-based enterprise, these application development has been gradually expanded based on reusable, independent, and portable components. Component Based Development (CBD) works by developing and evolving software from selected reusable software components and then assembling them within appropriate software architecture. However, it requires an increase in cost to build new components as well as the necessary effort to develop of the business requirement these components. Standardized component models are required as well from the perspective of systems in order to support rapid and exact component information transmission on the web. In this paper, we describe the e-Business Component Development with agent for rapid application development on the web that correspond to the demands of users in the business domain. We design and implement the specifications of e-business components by combining these demands. In order to improve the agent register and retrieval, we propose the intelligent search and register agents, which can conduct more precise searching and specializing for components. The system enables the locating of user's frequently used components through an agent involving register and retrieval, as well as rapid procedures for registers The e-BCOS (e-Business Component System) is the agent system for the user to register distributed components and to search for components Information. The e-BCOS increases reusability through the e-business component development of distributed components in the business domain. For the share and delivery, specification with XML is acceptable to user's variable order e-BCOS Includes the effective investment, timeliness, reliability, efficiency, and maintenance effort by with agent.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.27 no.5
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• pp.304-314
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• 2015

We have reviewed the current status of coastal vulnerability index(CVI) to be guided into an appropriate CVI development for Korean coast and applied a methodology into the east coast of Korea to quantify coastal vulnerability by future sea_level rise. The CVIs reviewed includes USGS CVI, sea_level rise CVI, compound CVI, and multi scale CVI. The USGS CVI, expressed into the external forcing of sea_level rise, wave and tide, and adaptive capacity of morphology, erosion and slope, is adopted here for CVI quantification. The range of CVI is 1.826~22.361 with a mean of 7.085 for present condition and increases into 2.887~30.619 with a mean of 12.361 for the year of 2100(1 m sea_level rise). The index "VERY HIGH" is currently 8.57% of the coast and occupies 35.56% in 2100. The pattern of CVI change by sea_level rise is different to different local areas, and Gangneung, Yangyang and Goseong show the highest increase. The land use pattern in the "VERY HIGH" index is dominated by both human system of housing complex, road, cropland, etc, and natural system of sand, wetland, forestry, etc., which suggests existing land utilization should be reframed in the era of climate change. Though CVI approach is highly efficient to deal with a large set of climate scenarios entailed in climate impact assessment due to uncertainties, we also propose three_level assessment for the application of CVI methodology in the site specific adaptation such as first screening assessment by CVI, second scoping assessment by impact model, and final risk quantification with the result of impact model.

• Development and Reproduction
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• v.13 no.4
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• pp.297-303
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• 2009

Implantation of blastocyst into the uterine endometrium is established by the existence of histologically and functionally prepared uterine endometrium. Doc-1, an oral cancer suppressor gene, is expressed under the control of steroid hormones and has been suggested as a proliferation regulator of endometrial cells. However, the role is not much clear and in this study we examined the expression modulation of Doc-1 in decidualizing cells in vitro. In vitro decidualization was performed in endometrial stroma cells using progesterone and estrogen. Until 24 hr after decidual induction the proliferation of stroma cell was significantly increased but decreased after then. On the other hand, most of the cells differentiated into decidual cell after 48 hr of induction. The Doc-1 protein was co-localized in a specific deciudal cells and colocalization rate was increased in a parallel manner with the induction time. Based on these results, it is suggested that Doc-1 expression is under the control of both steroid hormones and decidual signals, and Doc-1 protein is involved in suppression of the proliferation of decidualizing cells.

• Cartoon and Animation Studies
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• s.43
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• pp.387-433
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• 2016

The ability to develop curriculums is a crucial factor in evaluating the expertise of a teacher who teaches culture & art education. Establishing a one-year plan for classes is an effort to create a well-designed curriculum for the year and also to foresee the big picture of classes in the corresponding year. A curriculum should not be composed of merely educational content or a series of knowledge and skills. It should be well-designed, based on principles of a coherent plan. This study examines organizational principles on which common curriculums are based on and looks at how a curriculum can be designed, especially for cartoon & animation classes, as part of Culture & Art education, and which factors should be considered in planning. In the process of forming such a curriculum, these steps should be followed: considering educational standards for cartoon animation classes; determining the learning experience, organizing the learning experience; and, lastly, evaluating the level of learning. In addition, effective teaching strategies that reflect the characteristics of a class on cartoon animation should be formulated. This study suggests actual examples of an effective annual curriculum for cartoon animation classes based on all the factors presented above.

• Tunnel and Underground Space
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• v.29 no.6
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• pp.468-479
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• 2019

It is essential to comprehend coupled hydro-mechanical behavior to utilize subsurface for the recent demand for underground space usage. In this study, we developed a new simulator for numerical simulation as a tool for researching to consider the various domestic field and subsurface conditions. To develop the new module, we combined OpenGeoSys, one of the scientific software package that handles fluid mechanics (H), thermodynamics (T), and rock and soil mechanics (M) in the subsurface with FLAC3D, one of the commercial software for geotechnical engineering problems reinforced. In this simulator development, we design OpenGeoSys as a master and FLAC3D as a slave via a file-based sequential coupling. We have chosen Terzaghi's consolidation problem related to single-phase fluid flow at a saturated condition as a benchmark model to verify the proposed module. The comparative results between the analytical solution and numerical analysis showed a good agreement.

• Journal of Korean Society of Transportation
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• v.25 no.2 s.95
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• pp.17-26
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• 2007

Because the prime objective of the current preemption methods at signalized intersections near highway-railroad grade crossings(IHRGCs) is to clear the crossing, secondary objectives such as safe pedestrian crossing time and minimized delay often are given less consideration or are ignored completely during the preemption. Under certain circumstances state-of-the-practice traffic signal preemption strategies may cause serious pedestrian safety and efficiency problems at IHRGCs. An improved transition preemption strategy(ITPS) that is specifically designed to improve intersection performance while maintaining or improving the current level of safety was developed by Cho and Rilett. Even if the new transition preemption strategy improved both the safety and efficiency of IHRGCs, the performance of the strategy is affected by train speed. Understanding the impact of this factor is essential in order to implement ITPS. In this paper, the effects of train speed were analyzed using a VISSIM simulation model which was calibrated to field conditions. It was concluded that the delay is affected more by train speed than the transitional preemption strategy and the safety of the intersection is not affected by train speed once an advanced preemption warning time(APWT) is equal to or greater than 90 seconds.

• Journal of Life Science
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• v.18 no.6
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• pp.814-825
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• 2008

Ascochlorin (ASC) is prenyl-phenol compound that was isolated from the fungus Ascochyta viciae. ASC reduces serum cholesterol and triglyceride levels, and suppresses hypertension, tumor development, ameliorates type I and II diabetes. Here, to better understand the mechanisms by which ASC regulates physiological or pathological events and induces responses in the pharmacological treatment of inflammation, we performed differential analysis of the proteome of the mouse macrophage RAW264.7 cells in response to ASC. In this study, we used a proteomic analysis of LPS-induced RAW264.7 cells treated by ASC, to identify proteins potentially involved in inflammatory processes. The RAW264.7 cell proteomes with and without treatment with ASC were compared using two-dimensional electrophoresis (2-D SDS-PAGE), matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF-MS) and bioinformatics. The largest differences in expression were observed for the calreticulin (4-fold decrease), ${\beta}-actin$ (4-fold decrease) and vimentin (1.5-fold decrease). In addition, rabaptin was increased 3-fold in RAW264.7 cells treated with ASC. The expression of some selected proteins was confirmed by RT-PCR analysis.

• Tunnel and Underground Space
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• v.11 no.3
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• pp.257-269
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• 2001

Numerical simulation is performed to understand the structural behavior of an underground radwaste repository, assumed to be located at the depth of 500 m, in a granitic rock mats, in which a fault intersects the roof of the repository cavern. Two dimensional universal distinct element code, UDEC is used in the analysis. The numerical model includes a granitic rock mass, a canister with PWR spent fuels surrounded by the compacted bentonite inside the deposition hole, and the mixed bentonite backfilled in the rest of the space within the repository cavern. The structural behavior of three different cases, each case with a fault of an angle of $33^{\circ},\;45^{\circ},\;and\;58^{\circ}$ passing through the cavern roof-wall intersection, has been compared. And then fro the case with the $45^{\circ}$ fault, the hydro-mechanical, thermo-mechanical, and thermo-hydro-mechanical interaction behavior have been studied. The effect of the time-dependent decaying heat, from the radioactive materials in PWR spent fuels, on the repository and its surroundings has been studied. The groundwater table is assumed to be located 10m below the ground surface, and a steady state flow algorithm is used.

• Korean Journal of Microbiology
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• v.52 no.3
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• pp.365-374
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• 2016

In high-latitude regions, temperature has risen ($0.6^{\circ}C$ per decade) and this leads to the increase in microbial degradability against soil organic carbon (SOC). Furthermore, the decomposed SOC is converted into green-house gases ($CO_2$ and $CH_4$) and their release could further increase the rate of climate change. Thus, understanding the microbial diversity and their functions linked with SOC degradation in soil-thawing model is necessary. In this study, we divided tundra soil from Council, Alaska into two depth regions (30-40 cm and 50-60 cm of depth, designated as SPF and PF, respectively) and incubated that for 108 days at $0^{\circ}C$. A total of 111,804 reads were obtained through a pyrosequencing-based metagenomic study during the microcosm experiments, and 574-1,128 of bacterial operational taxonomic units (OTUs) and 30-57 of archaeal OTUs were observed. Taxonomic analysis showed that the distribution of bacterial taxa was significantly different between two samples. In detail, the relative abundance of phyla Actinobacteria and Firmicutes largely increased in SPF and PF soil, respectively, while phyla Crenarchaeota was increased in both soil samples. Weight measurement and gel permeation chromatography of the SOC extracts demonstrated that polymerization of humic acids, main component of SOC, occurred during the microcosm experiments. Taken together our results indicate that these bacterial and archaeal phyla could play a key function in SOC degradation and utilization in cold tundra soil.