• Title/Summary/Keyword: 만성 손상

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A method of background noise removal of Raman spectra for classification of liver disease (간 질병 분류를 위한 라만 스펙트럼의 배경 잡음 제거 방법)

  • Park, Aaron;Baek, Sung-June
    • Smart Media Journal
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    • v.2 no.2
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    • pp.33-38
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    • 2013
  • In this paper, we investigated baseline estimation methods for remove background noise using Raman spectra from acute alcohol liver injury and acute ethanol-induced chronic liver fibrosis. Far the baseline estimation, we applied first derivative, linear programming and rolling ball method. Optimal input parameter of each method were determined by the training rate of MAP (maximum a posteriori probability) classifier. According to the experimental results, classification results baseline estimation with the rolling ball algorithm gave about 89.4%, which is very promising results for classification of acute alcohol liver injury and acute ethanol-induced chronic liver fibrosis. From these results, to determined the appropriate methods and parameters of baseline estimation impact on classification performance was confirmed.

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Studies on the Effect of the Extract of Eugenia Flos on Gastritis and Gastric Lesion (급만성 위염 및 위손상에 관한 정향 추출물의 효과)

  • 정기화;이은방
    • Journal of Food Hygiene and Safety
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    • v.7 no.2
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    • pp.83-89
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    • 1992
  • This study was perfonned to investigate effectiveness eness on the gastritis and gastric lesion with the methanol extract of the flower buds of Eugenio caryophyllata. The extract was fractionated with hexane, chIorofonn, ethyl acetate, butanol, followed by bioassay Oil antigastritis. The ethyl acetate and the buthanol fraction reduced significantly HCI.ethanol induced gastric lesion at the dose of 165 and 215 mg/kg, p.o., respectively. These results may indicate that remarkably.effective are ethyl acetate and butanol fractions in HCI-ethanol induced gastric lesion. Howeever, the fractions didn't exhibit any inhibition of gastric secretion and acid output. The buthanol fraction reduced significantly the acetic acid induced ulcer at a daily dose of 215 mg/Kg, p.o., given for 10 days. These result showed considerable inhibit of acetic acid induced ulcer without inhibition of indomethacin induced gastric lesion. The methanol extract showed low acute toxicity with minimum lethal dose of more than 3000 mg/kg, p.o. in mice. In conclusion, Eugenia F10s exhibited antigastric activity which might be attributable to inhibition of gastric secretion. It is indicated that activie component may be present in the buthanol fraction.

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Diagnosis of Lateral Ankle Ligament Injury in the Evaluation of Chronic Lateral Ankle Instability (만성 외측 발목 불안정과 발목 인대 손상의 진단)

  • Ji Young Jeon
    • Journal of the Korean Society of Radiology
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    • v.82 no.6
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    • pp.1402-1412
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    • 2021
  • Chronic lateral ankle instability (CLAI) is a major complication of acute ankle sprain that can cause discomfort in both daily and sports activities and may lead to degenerative changes in the ankle joint as the long-term sequelae. The precise cause of CLAI remains debatable and is most probably multifactorial. However, identifying chronic lateral ankle ligament injury is critical in determining the primary etiology and formulating an appropriate treatment plan. This review discusses the features and effectiveness of various imaging techniques in diagnosing chronic lateral ankle ligament injury.

The Spinal Flexibility and Response Time of Erector Spinae Muscle Following Stabilization Exercise (만성 요통 환자에서 척추 유연성과 허리 근육 반응속도 분석)

  • Sung, Paul S.
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.6 no.1
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    • pp.35-49
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    • 2000
  • 허리 근육손상은 기대치 못한 상황에서 신체의 적절한 반응이 지연될 경우 근육 염좌와 같은 상해나 요통으로 연결된다. 이 연구는 척추 안정 운동 후 척추의 유연성과 척추 근육의 반응 속도를 만성 요통 환자와 정상인을 대상으로 비교 연구 하였다. 만성 요통 환자 군은 척추 안정 운동을 4주간 20회 시행하였으며 이와 비슷한 특성을 가진 대조군을 비교하였다. 신체 유연성은 환자가 앉은 자세에서 척추를 축으로 신체의 회전 정도를 측정하였다. 척추 반응 속도 측정은 환자가 선 자세에서 두 손으로 판을 들고있는 동안 정구공이 1.8 m (6.4 N)에서 낙하시 좌, 우측 척추 근육의 반응 속도를 Wavelet 분석으로 측정하였다. 연구 결과 척추 안정 운동을 행한 만성 요통 환자군의 신체 유연성과 척추 근육 반응 속도가 통계적으로 유의하게 증가하였다. 척추 유연성은 만성 요통 환자 군에서 131.0cm에서 척추안정 운동후 144.1cm으로 증가하였다 (p<0.05). 척추 근육 반응 속도는 척추 안정 운동을 행한 만성 요통 환자 군에서 90.00msec에서 68.55msec로 (p<0.05), 정상 군에서는 86.28msec에서 75.64msec로 (p>0.05) 단축되었다. 척추 안정 운동은 근, 신경 조직의 반응속도를 증가시키며 특히 만성 요통 환자에서 척추의 안정성을 회복시킨다. 특히 척추의 안정성 증가는 기대치 못한 상황에서 선체의 적절한 반응의 속도를 회복시키며 결과적으로 허리 손상을 예방 할 수 있다. 물리치료학에서 근 골격 신경계의 반응 속도측정을 위한 연구로 Wavelet 분석과 같은 첨단장비를 통한 운동 치료의 질에 관한 연구의 도입이 필요하다. 또한 구체적인 치료적 운동결과의 측정을 통해 물리 치료의 효과성과 효율성을 높이기 위한 생체 의학적 연구가 요망된다.

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Arthroscopic Management in Chronic Osteomyelitis (만성 골수염의 내시경적 처치 - 증례 보고 2예 -)

  • Lee Beom Koo;Eom Gi Serk;Ki Yong Chul;Cho Hyun Yee
    • Journal of the Korean Arthroscopy Society
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    • v.6 no.2
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    • pp.192-194
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    • 2002
  • The goal of surgery of chronic osteomyelitis is removal of dead bone and achieving a viable and vascular environment. During saucerization, the sequestrum could be checked and resected completely. But it can causes vascular injury by massive soft tissue dissection in saucerization of chronic osteomyelitis. Recently, we experienced medulloscopy in the treatment of chronic osteomyelitis and it is possible for us to visualize the sequestrum, to do complete resection of dead bone and to reduce vascular injury during operation.

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A Convergence Study in the Severity-adjusted Mortality Ratio on inpatients with multiple chronic conditions (복합만성질환 입원환자의 중증도 보정 사망비에 대한 융복합 연구)

  • Seo, Young-Suk;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.13 no.12
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    • pp.245-257
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    • 2015
  • This study was to develop the predictive model for severity-adjusted mortality of inpatients with multiple chronic conditions and analyse the factors on the variation of hospital standardized mortality ratio(HSMR) to propose the plan to reduce the variation. We collect the data "Korean National Hospital Discharge In-depth Injury Survey" from 2008 to 2010 and select the final 110,700 objects of study who have chronic diseases for principal diagnosis and who are over the age of 30 with more than 2 chronic diseases including principal diagnosis. We designed a severity-adjusted mortality predictive model with using data-mining methods (logistic regression analysis, decision tree and neural network method). In this study, we used the predictive model for severity-adjusted mortality ratio by the decision tree using Elixhauser comorbidity index. As the result of the hospital standardized mortality ratio(HSMR) of inpatients with multiple chronic conditions, there were statistically significant differences in HSMR by the insurance type, bed number of hospital, and the location of hospital. We should find the method based on the result of this study to manage mortality ratio of inpatients with multiple chronic conditions efficiently as the national level. So we should make an effort to increase the quality of medical treatment for inpatients with multiple chronic diseases and to reduce growing medical expenses.