• Journal of Preventive Medicine and Public Health
• /
• v.35 no.2
• /
• pp.129-135
• /
• 2002

Objective : The primary objective of this study was to estimate the prevalence of HBsAg-positives in the late 1990's among Korean adults. In addition, we evaluated the association of age, a residential area, a vaccination rate, a family history of chronic liver diseases and a past history of acute liver disease with the seropositivity of HBsAg, and estimated the prevalence of chronic HBV infection by follow-up for 6 month or more. Methods : A total of 10 areas, six metropolitan and four small cities, were selected. In each cities, one health screening center was selected for recruitment of study subjects. The study subjects were enrolled from a general health examination program that is provided by medical insurance companies. Questionnaires on various risk factors were administered to the study subjects. Sera was drawn and tested for HBsAg by radioimmunoassay. HBeAg and ALT were also tested for those of HBsAg positive. The HBsAg positives was retest for HBsAg 6 months later Results : Among the study subjects (n= 1816), the seroprevalence of HBsAg was 5.5% (95% CI=4.5%-6.6%), 7.4% in men (95% CI=5.8-9.4) and 3.6% in women (95% CI=2.5-5.0). A past history of acute liver disease and a family history of chronic liver diseases was shown to be risk factors for HBsAg positivity. Among the 31 HBsAg-positives, negative seroconversion rate was estimated to be 3.2%, Thus, prevalence of chronic HBV infection was estimated to be 5.3% (95% CI=3.7-6.6). Conclusion : In this study, the HBsAg seroprevalence rate was lower than that of the other studies in 1980's, particularly in young adult and women. Considering the public health importance of liver cancer and chronic liver diseases, the further effort is needed to prevent and reduce the HBV infection.

• Proceedings of the Korean Information Science Society Conference
• /
• 2012.06a
• /
• pp.197-199
• /
• 2012

최근에 우리 사회는 불규칙적인 식습관, 부족한 운동, 과도한 스트레스 등으로 만성질환 및 성인병 환자가 늘어나는 심각성이 날로 커지고 있다. 성인병의 심각성은 40대 이상에서 크게 대두 되었던 과거와 달리, 최근에는 20대를 넘어서서 10대 청소년에게까지 성인병을 앓고 있는 환자들이 날로 많아지고 있다. 세계적으로 IT가 크게 발달함에 따라 병원과 환자가 서로 만나지 않아도 24시간 소통이 되는 u-Healthcare 시스템이 크게 대두되고 있다. 이에 따라서 환자 개개인과 주치의가 시 공간에 제약받지 않고 상호 긴밀하게 진료, 검사 및 피드백이 가능하게 된다. 본 연구진은 u-Healthcare 시스템에 부합하고 스마트 폰을 이용하여 만성질환자를 관리할 수 있는 u-DailyCare 시스템을 설계하고 구현하였다. 스마트 폰 사용자로부터 얻어진 생체 정보 데이터 및 행위 데이터들을 수집하여 서버에 보내면, 주치의는 종합된 전체적인 데이터를 실시간으로 확인하여 환자의 상태를 검토 및 진단하여 피드백을 준다. 본 논문에서는 u-DailyCare 시스템의 설계 및 구현과정을 설명할 것이다.

• Child Health Nursing Research
• /
• v.24 no.1
• /
• pp.101-108
• /
• 2018

Purpose: This study aimed to identify the effects of the mother-medical staff partnership on mothers' condition management ability for children with chronic allergic diseases. Methods: A total of 109 Korean mothers caring for a child with a chronic allergic diseases, identified according to the allergic march, such as food allergy, atopic dermatitis, allergic rhinitis, and allergic asthma, were recruited from the pediatric department of a general hospital in Seoul through convenience sampling. Data were collected using structured self-reported questionnaires from August 1, 2017 to October 31, 2017. and analyzed by descriptive statistics and multiple regression using SPSS version 22.0. Results: The Mother-medical staff partnership had a statistically significant effect on mothers' condition management ability for children with chronic allergic diseases (p<.05). Among the general characteristics, satisfaction with nursing services had a statistically significant effect on mothers' condition management ability (p<.05). Conclusion: In conclusion, strategies to support children with chronic allergic diseases, as well as their caregivers, should consider the mother-medical staff partnership as part of a family-centered approach.

• Information and Communications Magazine
• /
• v.29 no.10
• /
• pp.66-73
• /
• 2012

전 세계적으로 노령인구가 급격히 증가하면서 만성질환자도 급증하고 있는 추세이다. 또한, 고도화된 현대사회와 과도한 업무, 서양화된 식습관, 그리고 운동부족은 젊은 층에서의 성인병 및 만성질환 증가를 부추기고 있다. 만성질환의 증가는 의료비 증가로 이어지고 결국은 국가재정 부담으로 돌아가게 된다. 만성질환자의 대부분은 지속적인 생체정보 측정과 이를 통한 관리가 필수적인데 매번 병원을 방문해 관리하는 것은 현실적으로나 비용적인 측면으로나 무리가 있는 것이 사실이다. 이러한 문제를 해결하고 언제 어디서나 시간과 공간에 구애받지 않고 생체정보를 원격에서 측정하고 관리 받을 수 있도록 하는 것이 U-헬스케어 서비스이다. U-헬스케어 서비스는 전통적인 의료 서비스에 정보통신 기술을 접목한 형태로 고령인구 및 만성질환자의 지속적인 관리를 위해 현재 주목 받고 있는 기술이다. U-헬스케어 서비스의 가장 중요하면서도 기본적인 요소는 원격지 사용자의 생체정보를 측정하고 수집할 수 있는 원격 생체정보 모니터링 기술이다. 이를 위해서는 다양한 종류의 생체정보 측정기기가 필요한데 장비나 시스템 간 통신 인터페이스의 상호 호환성이 매우 중요하다. 본 논문에서는 원격 생체정보 모니터링을 위한 표준 기술인 IEEE 11073 PHD를 소개하고 현재 IEEE 11073 PHD 표준에서 명시하고 있지 않은 보안 문제점과 필요 기술들을 분석하고자 한다. 또한, IEEE 11073 PHD에서 IEEE 11073-20601 표준 프로토콜을 이용한 사용자 인증 구조를 제안한다.

• Journal of Korean Biological Nursing Science
• /
• v.25 no.4
• /
• pp.229-242
• /
• 2023

Purpose: The electronic frailty index (eFI), which is derived from electronic health records, has been recommended as screening tool for frailty due to its accessibility and ease of use. The objective of this systematic review was to identify the prevalence of frailty assessed by the eFI and its influence on health outcomes in older adults with chronic diseases. Methods: We searched PubMed, Embase, Web of Science, CINAHL, SCOPUS, Cochrane, Google search, and nursing journals in Korean from January 2016 to December 2022. Results: Twelve studies were analyzed. The eFI score, based on routine clinical data, was associated with adverse health outcomes. The most frequent outcome studied was mortality, and the eFI was associated with increased mortality in nine studies. Other outcomes studied included hospitalization, length of stay, readmission, and institutionalization in relation to hospital care usage, and cardiovascular events, stroke, GI bleeding, falls, and instrumental activities of daily life as health conditions. Conclusion: Early identification of frailty in older adults with chronic diseases can decrease the burden of disease and adverse health outcomes. The eFI has a good discriminative capacity to identify frail older adults with chronic diseases.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2013.11a
• /
• pp.417-420
• /
• 2013

고혈압과 당뇨와 같은 만성질환은 장기적인 관리가 필요하다. 최근 주목받고 있는 폐쇄형 SNS 시스템 설계를 통해서 동일한 질병을 가지고 있는 그룹간의 커뮤니케이션을 활성화하여 자유로운 게시글을 통해서 환자 맞춤형 건강정보를 발굴하고 공유하는 시스템을 안드로이드 어플리케이션을 통해서 구현하였다. 본 서비스를 통해서 건강정보 공유 서비스 연구가 활성화될 것으로 기대한다.

• Journal of agricultural medicine and community health
• /
• v.44 no.4
• /
• pp.165-184
• /
• 2019

Objectives: The purpose of this study was to identify and compare the difference and related factors with general characteristic and health behaviors, a experience of diagnosis and treatment of chronic diseases between rural and urban among elderly in Korea. Methods: We used the data of Community Health Survey 2017 which were collected by the Korean Center for Disease Control and Prevention. The study population comprised 67,835 elderly peopled aged 65 years or older who participated in the survey. The chi-square test, univariate and multivariate logistic regression analysis were used to analyze data. Results: We identified many significant difference of health behaviors, an experience of diagnosis and treatment with chronic diseases between rural and urban. Compared to urban elderly, the odds ratios (ORs) (95% confidence interval) of rural elderly were 1.136 (1.092-1.183) for diagnosis of diabetes, 1.278 (1.278-1.386) for diagnosis of dyslipidemia, 0.940 (0.904-0.977) for diagnosis of arthritis, 0.785(0.736-0.837) for treatment of arthritis, 1.159 (1.116-1.203) for diagnosis of cataracts, and 1.285(1.200-1.375) for treatment of cataracts. In the experience of diagnosis and treatment of chronic diseases, various variables were derived as contributing factors for each disease. Especially, there were statistically significant difference in the experience of diabetes diagnosis, arthritis diagnosis, cataract diagnosis and dyslipidemia except for hypertension diagnosis (p <0.01) between urban and rural elderly. There were statistically significant differences in the experience of treatment for arthritis and cataract (p <0.01), but there was no significant difference in the experience of treatment for hypertension, diabetes, dyslipidemia between urban and rural elderly. Conclusion: Therefore, it would be necessary to implement a strategic health management project for diseases that showed significant experience of chronic diseases with diagnosis and treatment, reflecting the related factors of the elderly chronic diseases among the urban and rural areas.

• Journal of the Korean Applied Science and Technology
• /
• v.41 no.2
• /
• pp.459-471
• /
• 2024

In modern society, where tension and stress are ubiquitous, individuals often experience psychological imbalances. These stressors not only affect mental well-being but also manifest physically, through the skin. Consequently, a new term psychodermatology combining psychiatry and dermatology, has emerged, garnerning attention and research focus. In this study, we aimed to develop materials improving chronic skin conditions caused by stress by utilizing a compound of Cucurbita moschata, Paeonia japonica, and Prunus cerasus known to alleviate skin disorders. We sought to develop and validate the efficacy of materials alleviating chronic skin conditions induced by stress in keratinocytes..Therefore, in this study we analyzed the effects of a complex extract using Cucurbita moschata, Paeonia japonica, and Prunus cerasus on HaCaT keratinocyte cells to understand how it influences them. The complex extract on HaCaT keratinocyte cells showed a concentration-dependent decrease in the expression levels of TNF-α, IL-1β, IL-6, MDC, and TARC at concentrations of 12.5, 25, 50 and 100 ㎍/mL. Particularly noteworthy was the efficacy observed in inhibiting IL-1β, with a reduction of over 40% at a concentration of 100 ㎍/mL. Additionally, the production levels of AQP-3, HA, and filaggrin exhibited a significant concentration-dependent increase. The protein expression of p-ERK, p-JNK, and p-p38, which were elevated by TNF-α/IFN-γ, was significantly decreased with the treatment of the complex extract. These findings suggest that the compound extract may be utilized as a material for treating and preventing skin conditions, potentially mitigating the adverse effects of the mutual relationship between skin disorders and stress.

• Journal of Life Science
• /
• v.24 no.11
• /
• pp.1238-1243
• /
• 2014

Mesenchymal stem cells (MSCs) have been widely used as cellular therapeutic agents. They have their own characteristic stemness, and thus, they can be used in the treatment of many chronic diseases and in anticancer therapy. MSC therapy has many advantages over chemical therapy. MSC therapy is based on self or homogeneous origin; as such, it is expected to be effective in the treatment of various diseases. In addition, microRNAs in particular have been studied for their structure and function, and they are also expected to prove effective for use as therapeutic agents in cancer or chronic diseases. MicroRNAs are largely associated with metabolism and homeostasis. Therefore, over- or under-expression of microRNAs leads to chronic diseases. Conversely, effective control of the expression of specific microRNAs reduces the risk of many chronic diseases. However, there have been no reports thus far on the synergistic effects of MSCs and microRNAs. Therefore, in this study, we examined the relationship between MSCs and microRNAs using placenta-derived MSCs (PDSCs), bone marrow-derived MSCs (BM-MSCs), and fibroblast (WI-38) cells. We studied the expression of some microRNAs in MSCs and compared the expression in each cell line and cell passage. As a result, we found that the expression of microRNA-34a was higher in PDSCs than in BM-MSCs and that the expression of microRNA-27a, 33a, 33b, and 211 was higher in BM-MSCs than in PDSCs. Therefore, we expect that each MSC line will be used as cell therapy, considering its expressed functional microRNA.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.3
• /
• pp.485-492
• /
• 2017

This study was conducted to identify the preservice teacher's health perception and health promoting behavior, and attitudes towards children with asthma, as well as to examine the relationship between these variables and the influencing factors. The participants were 329 third and fourth grade students from the national university of education in G city. The data were analyzed using Pearson correlation coefficients, t-test, ANOVA, Scheffe test, and multiple regression with SPSS/WIN 23.0. The score for the participants' health perception was 2.85 out of a possible 4, health promoting behavior about 2.49 out of a possible 4, and their score for attitude towards asthma was 3.67 points of a possible 5. The health perception and health promoting behavior showed a positive correlation with the attitudes about child with asthma. Interpersonal relations and health perception and grade had a significant influence on the attitudes about child with asthma. These variables accounted for 12.2% of the attitudes about child with asthma. The results highlight the need for intervention strategies to enhance the health promoting behavior and health perception.