• Title/Summary/Keyword: 류마티스

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A Study on Depression and Activity of Daily Living in Patients with Rheumatoid Arthritis by Gender (성별에 따른 류마티스 관절염 환자의 우울과 일상활동정도)

  • Yoo, Kyung Hee
    • Journal of muscle and joint health
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    • v.20 no.2
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    • pp.131-140
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    • 2013
  • Purpose: The purpose of this study was to investigate depression and activity of daily living of patients with rheumatoid arthritis by their gender. Methods: The subjects for this study were 184 patients registered in S University Hospital. and the period of data collection was from May 1, 2012 to August 20, 2012. The data were analyzed with t-test, ANOVA, Mann-Whitney U test, Kruskal-Wallis H test, and Pearson's correlation. Results: For depression, there were significant differences by marriage and religion in male patients and by education in female patients. For activity of daily living, there were significant differences by marriage, age and education in female patients. Depression was negatively correlated with activity of daily living in patients with rheumatoid arthritis. Conclusion: Managing depression and activity of daily living were important for both male and female patients with rheumatoid arthritis. To promote the quality of life of patients with rheumatoid arthritis, nursing intervention strategies must be developed for decreasing depression or improving their activity of daily living.

Usage of T Cell Receptor Repertoire is Restricted in Synovial Lymphocytes in Rheumatoid Arthritis (류마티스양 관절염 환자 활막 T 세포의 T 세포수용체 β쇄 분석)

  • Kwon, Dae-ho;Lee, Soo-Kon;Kim, Se-Jong;Choi, In-Hong
    • IMMUNE NETWORK
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    • v.1 no.1
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    • pp.70-76
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    • 2001
  • Background: Rheumatoid arthritis is an autoimmune disease characterized by a chronic inflammatory process, primarily involving the synovial membrane of peripheral j oints, where T cell activation is found. To address the superantigen stimulation in rheumatoid arthritis, T cell clonality and the expression of activation markers were analyzed. Methods: To detect TCRB V usage, inverse PCR and sequencing were done. Monoclonal antibodies were used for flow cytometric analysis of TCRBV8 or TCRBV5. As results, a restricted usage of TCRBV3 gene was detected in synovial lymphocytes from one rheumatoid arthritis patient. However, preferential usage for TCRB V8, which may be one indicator for stimulation by staphylococcal superantigen, was not obvious although general activation of T cells was found as high DR+ percentage in synovial T cells. These data show specific antigen rather than superantigen might involve the pathogenesis of rheumatoid arthritis.

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Learned Helplessness to Predict Regular Physical Activity among Individuals with Rheumatoid Arthritis (학습된 무력감이 류마티스관절염 대상자의 규칙적 운동에 미치는 영향)

  • Boo, Sunjoo;Oh, Hyunjin
    • Journal of muscle and joint health
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    • v.24 no.2
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    • pp.150-158
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    • 2017
  • Purpose: Regular physical activity is beneficial in reducing disease activity and morbidity in patients with rheumatoid arthritis (RA). The purposes of this study were to examine the levels of regular physical activity and learned helplessness and to identify factors influencing in participation in regular physical activity in RA patients. Methods: This cross-sectional study was conducted with 210 RA patients in a university-affiliated hospital. Participants completed a questionnaire including demographic and disease-related characteristics, physical activity and learned helplessness. Data were analyzed with descriptive statistics, $x^2$ tests, t-tests, and multivariate logistic regression analyses. Results: About 23% of RA patients engaged in at least 30 minutes of regular physical activity per week. Patients with being older (OR=1.09, 95%CI=1.03~1.14), no employment status (OR=0.17, 95% CI=0.07~0.42), and lower levels of learned helplessness (OR=0.58, 95% CI=0.34~0.96) had significantly higher chance of engaging in regular physical activity. Conclusion: In developing nursing interventions to promote regular physical activity in RA patients, their learned helplessness should be considered.

The Relationship among the degrees of pain coping strategies, Pain and Depression of patients with Rheumatoid Arthritis (류마티스 관절염 환자의 통증대처, 통증 및 우울정도의 관계)

  • Park, Gyung;Choi, Soon-Hee
    • Journal of muscle and joint health
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    • v.5 no.2
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    • pp.253-264
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    • 1998
  • This study has done for the purpose of investigation among the degrees of pain coping strategies, pain, and depression of patients with rheumatoid arthritis. The subjects of this study were 214 patients diagnosed with rheumatoid arthritis. The data were collected from september 4 to 16, 1995 by questionnaires. The data were analysed by the use of frequency, t-test, Pearson Correlation Coefficients, ANOVA, and Duncan test. The results Were as follows ; 1. The mean score of pain was 213.5(range : 4-390) and that of depression was 21.4 (range : 1-50). The mean score of passive pain coping strategies was 30.2(range : 11-48) and that of active pain coping strategies was 18.6(range : 7-33) 2. The passive pain coping degree showed a positive correlation with the pain degree (r=.475, p=.0001) and the active pain coping degree showed a inversive correlation with that(r= -.296, p=.0001). The passive pain coping degree showed a positive correlation with the depression degree (r=.425, p=.0001) and the active pain coping degree showed a inversive correlation with that(r=-.299, p=.0001). The pain degree showed a positive correlation with the depression degree(r=.374, p=.0001).

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