• Journal of Microbiology and Biotechnology
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• v.22 no.12
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• pp.1790-1794
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• 2012

Recently, it has been suggested that $p27^{Kip1}$, the cell cycle regulatory protein, plays a pivotal role in the progression of normal differentiation in murine embryonic stem (mES) cells. In the current study, we investigated the role of $p27^{Kip1}$ in the regulation of differentiation and apoptotic induction using Western blotting, quantitative real-time RT-PCR, and small interfering RNA (siRNA) assays and confocal laser scanning microscopic analysis of H9 human ES (hES) cells and H9-derived embryoid bodies (EBs) grown for 10 ($EB_{10}$) and 20 days ($EB_{20}$). Our results demonstrate that the proteins $p27^{Kip1}$ and cyclin D3 are strongly associated with cellular differentiation, and, for the first time, show that up-regulation of $p27^{Kip1}$ protects hES cells from inducing differentiation-associated and caspase 3-dependent apoptosis.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.9 s.339
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• pp.73-80
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• 2005

The Turbo decoders based on Log-MAP decoding algorithm inherently requires large amount of memory and intensive complexity of hardware due to iterative decoding, despite of excellent decoding efficiency. To decrease the large amount of memory and reduce hardware complexity, the result of previous research. And this paper design the Turbo decoder applicable to the 3G W-CDMA systems. Through the result of previous research, we decided 5-bits for the received data 6-bits for a priori information, and 7-bits for the quantization state metrics. The error correction term for $MAX^{*}$ operation which is the main function of Log-MAP decoding algorithm is implemented with very small hardware overhead. The proposed Turbo decoder is synthesized in $0.35\mu$m Hynix CMOS technology. The synthesized result for the Turbo decoder shows that it supports a maximum 9Mbps data rate, and a BER of $10^{-6}$ is achieved(Eb/No=1.0dB, 5 iterations, and the interleaver size $\geq$ 2000).

• Journal of Korea Multimedia Society
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• v.9 no.6
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• pp.728-734
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• 2006

Carrier interferometry code is considered as a promising scheme that provides significant performance improvement via frequency diversity effect. Space-time coding is commonly employed to achieve a performance gain through space diversity. The combination of these techniques and forward error correction coding will lead to enhanced system capacity and performance. This paper presents a low-density parity check (LDPC) coded space-time orthogonal frequency division multiplexing (OFDM) transmission scheme with carrier interferometry code for high-capacity and high-performance mobile multimedia communications. Computer simulations demonstrate that the proposed mobile multimedia transmission system offers a considerable performance improvement of approximately 9dB in terms of Eb/No in the Rayleigh fading channel with relatively low delay spread, in comparison with space-time OFDM. Performance gains are further increased, comparing with traditional OFDM systems.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.2
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• pp.175-180
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• 2002

In this paper, the system performace with the convolution rode using a Viterbi decoding and the one tap LMS(Least Meam Square) equalizer applied to the OFDM(Orthogonal Frequency Division Multiplexing) system, is analyzed through computer simulation. DMRS(Digital Microwave Radio System)is modeled as Rummler fading channel. In Simulation result, we known that the coding system improved about 3.6dB~10.5dB when BER is 10 $^3$and b is 0.1~0.2 in case of 16QAM(Qurdrature Amplitude Modulation). Also, we known that was improved about 19.7dB when the b is 0.1 and was demanded about 10.5dB when the b is 0.2 in case of 64QAM. we known that the soft decision improved about 2~0.9dB when the b is 0.1~0.2 in case of 16QAM and about 3.3~7.8dB in case of 64QAM. In the equalizer system, efficiency improved from the case of that Eb/No is more than 13dB.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.12
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• pp.1300-1310
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• 2003

In this paper, the performance of a multicarrier CDMA system using adaptive modulation and adaptive subchannel allocation scheme is analyzed in Rayleigh fading channel. The proposed adaptive modulator consists of modulation schemes using QPSK 16 QAM, 64 QAM and 256 QAM and constellations are pointed by Gray code. In addition, the threshold of the analysis is average E$\_$b//N$\_$o/ when the BER is 1 %. In the multicarrier system with adaptive subchannel allocation scheme, each DS waveform of user is transmitted over the K subchannels with the biggest fading among L subchannels. In case of the proposed system, total 4 subchannels are used and data are transmitted over 2 subchannels with the biggest fading, which results in the threshold of each channels is 5.2 dB, 9 dB, 13.2 dB and 8.4 dB, 12.2 dB, 16.3 dB. In the case of proposed system, the BER of 10$\^$-3/ is satisfied if average E$\_$b//N$\_$o/ is 8.1 dB. This is increased performance of 12.9 dB in comparison with conventional system. The BPS according to average channel is needed average E$\_$b//N$\_$o/ of about 15 dB in 7 bit. In the case of subchannel error, the BER of 10$\^$-3/ is 13.6 dB and is declined about 5.5 dB.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.9C
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• pp.721-728
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• 2010

CAMC (constant amplitude multi-code) has a better performance of error correction in iterative decoding than SPCPC (single parity check product code). CAMC benefits from a processing gain since it belongs to a spread spectrum signal. We show that the processing gain enhances the performance of CAMC. Additional correction of bit errors is achieved in the de-spreading of iteratively decoded signal. If the number of errors which survived the iterative decoding is less than or equal to ($\sqrt{N}/2-1$), all of the bit errors are removed after the de-spreading. We also propose a stopping criterion in the iterative decoding, which is based on the histogram of EI (extrinsic information). The initial values of EI are randomly distributed, and then they converge to ($-E_{max}$) or ($+E_{max}$) over the iterations. The strength of the convergence reflects how successfully error correction process is performed. Experimental results show that the proposed method achieves a gain of 0.2 dB in Eb/No.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.9
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• pp.47-54
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• 2004

The previous works for WLAN system based on OFDM is mainly individual study for independent frequency offset or symbol synchronization. In this paper, the performance of IEEE 802.11a WLAN(Wireless Local Area Network) system in the realistic indoor multipath channel models is analyzed with frequency offset compensation and channel estimation methods. For the performance analysis of the WLAN system indoor Rayleigh multipath channels are adopted, and the BER(Bit Error Rate) of WLAN system is calculated with y2 code-rate 16-QAM based on standard specification. From the simulation results, the difference of required Eb/No for BER of 10-3 is 1-2dB between the channel estimation and frequency offset compensation, and perfect channel estimation and no frequency offset.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.12
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• pp.1352-1370
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• 2010

In this paper, we investigated the shadow area of radio programs which are currently being broadcast via FM 102.5 MHz in Jeollabuk-do consisting of 6 cities and 8-guns. The field strength data of FM 102.5 MHz was used with criterion of shadow area. As a result, the field strength of the eastern mountainous area in Jeollabuk-do was very low. We also measured, compared and analyzed the field strength of 102.5 MHz(TBN-Jeonju), 100.7 MHz(KBS) and 99.1 MHz (MBC) in Jeollabuk-do. Based on the field strength data, we tried to find what correlation exists and how much influence is between difference of antenna output power and solution of shadow area. In result, enhancement of antenna output power is not solution in terms of reducing the shadow Area of 102.5 MHz(TBN-Jeonju). In addition, we measured, compared and analyzed the field strength of 102.5 MHz(TBN-Jeonju) and 106.9 MHz(EBS). In fact, the relay stations with 104.1 MHz, 104.9 MHz, 105.3 MHz and 107.5 MHz of EBS FM has a number of FM relay stations in the eastern mountainous area of Jeollabuk-do. As a result, we confirmed that EBS almost did not have shadow area in the eastern mountainous area of Jeollabuk-do based on the field strength data. As in the case of EBS and KBS, we suggest installing TBN-Jeonju FM relay station with the best solution to reducing the shadow area to extend the audible range of TBN-Jeonju.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.9
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• pp.67-74
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• 2016

This paper presents a novel multiple orthogonal subcarrier modulation based UHF band RFID communication system. In tag-to-reader communication, the demonstration system can deliver 1.6 Mbps through four subcarriers. To improve data rate while suppressing increase in circuit complexity, tag employs square-waves as the subcarriers and uses individual load modulators for each subcarrier. By using multiple orthogonal subcarrier based modulation, proposed communication system can be operated under existing UHF band RFID regulation. In reader, an OFDM demodulator is used. Since the tag backscatters the reader's CW carrier, carrier frequency offset compensation is not necessary in reader demodulator. Experimental results show that the demonstration system achieves a bit error rate of 10-5 at an Eb/N0 of 10.8 dB.

• Journal of Embryo Transfer
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• v.16 no.3
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• pp.193-201
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• 2001

This study was designed to examine the factors affecting in fertilization and development of embryos in vitro, and to examine whether zone drilling by laser irradiation can improve the hatching rate of IVF embryos from DNA marker-proved Hanwoo. DNA markers related to marbling score were identified using DNA fingerprinting with Ml3 probe and restriction enzyme Hae III. Oocytes were aspirated from immature ovarian follicles using a combined method of rectal ovarian-palpation and transvaginal ultrasound-guidance(6.5MHz) under local anesthesia. The aspirated oocytes were washed twice with fresh D-PBS containing 5% FBS and were rewashed 4 to 5 times with TCM-199 containing 5% FBS. A morphological grade of I to IV was assigned to each oocyte. Data were analyzed using the GLM procedure of SAS. Sperm separation methods did not have any significant effect on cleavage or developmental abilities of IVF embryos. Significantly(P<0.05) higher cleavage rate was observed in embryos from GI(60.0%, 3/5), GII(69.2%, 18/26) and GIII(62.1%, 59/95) compared to embryos from GIV oocytes(36.2%, 25/69). And the developmental rate to blastocyst stage was higher(P<0.05) in embryos from GI(33.3%, 1/3) and GII oocytes(38.9%, 7/18) than those from GIII(16.9%,10/59) and GIV oocytes(4.0%, 1/25). There was no significant difference in development of IVF embryos to blastocyst by media for in vitro culture. Proportion of hatched blastocyst was significantly(P<0.05) higher in embryos received zona drilling by laser than those of non-drilled.