• Proceedings of the Korean Society of Applied Pharmacology
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• 1997.04a
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• pp.85-85
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• 1997

스트레스가 유발된 랫드의 대뇌에서 Vasopressin-catecholamine pathway의 활성도를 알아보기 위해 면역화학염색법으로 vasopressin 호르몬의 분비와 catecholamine의 생성변화를 tyrosine hydroxylase (TH) 효소의 발현변화로 규명하고, arginine vasopressin (AVP)과 V1 vasopressin receptor의 유전자 발현변화를 in situ hybridization 방법을 이용하여 살펴보았다. 수컷 SD rat를 7시간동안 stress cage에 넣어 16$\pm$1$^{\circ}C$의 물에 수침구속 스트레스를 준 후 대조군과 함께 관류고정하여 brain을 적출하였다. Brain의 hypothalamus 부위를 중심으로하여 동결절편하여 면역조직화학 염색과 in situ hybridization을 시행하였다. TH 면역조직화학 염색에서 대뇌의 줄무늬체 부위의 꼬리조가비핵에서와 시상하부 부위의 내측등쪽시상하부와 흑색질부위에서 스트레스군이 대조군에 비해 TH 면역염색성이 증가되어 관찰되었으나 시상하부 부위의 시삭위핵, 뇌실주위핵, 뇌실옆핵에서는 두 군간의 큰 면역염색성의 차이는 보이지 않았다. AVP 면역조직화학 염색에서는 시삭위핵에 많은 수의 AVP 양성 신경세포체들이 밀집되어 있으며 뇌실옆핵에서는 스트레스군에서 AVP 면역염색성이 약간 증가되어 관찰되었으나 신경섬유의 분포양상은 비슷하였다. 중간융기에서는 모두 강한 염색성의 신경섬유들이 관찰되어 두 군간에 큰 차이는 없었다. AVP 유전자에 대한 in situ hybridization 결과 시삭위핵의 신경세포에서 AVP mRNA 양성반응을 관찰할 수 있었으나 다른 시상하부핵에서는 관찰할 수 없었으며, V1 vasopressin receptor에 대한 in situ hybridization 결과는 두 군의 대뇌에서 모두 양성반응을 관찰할 수 없었으며 V1 vasopressin receptor 유전자의 조직별 발현정도와 스트레스에 의한 발현량 조절을 관찰할 필요가 있다고 사료된다.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.833-841
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• 2008

Recently, the upheaval generation in the road which is under service had been reported. Due to the upheaval generation, total 4 lanes were forced to curtail to 3 lanes, and traffic was delayed. In normal situation of cut-slopes in korea, that condition is hard to detect since most cut-slopes contain discontinuous material, that is rock. Common collapses in rock-slopes is wedge failure, plane failure and toppling failure which is all individual mechanism of discontinuous rock mass. In contrast, such upheaval in the road in front of cut-slope can be generated only when circular movement is triggered within the cut-slope. In this sense, rock-slopes barely show any kind of movement in the road locates at the front of them. Numerical analysis is general method in simulation of slope displacement and evaluation of safety. However, numerical analysis programs which are related with rock-slopes are not able to simulate such upheaval movement because that programs are based on discontinuous modeling mechanism. In addition, although numerical analysis programs which are based on FEM/FDM and thus utilize continuous modeling mechanism are able to simulate circular movement and upheaval situation, they have weakness in reflecting discontinuities of rock-slope itself. In this study, detailed in-site investigation and numerical analysis based on in-site condition were performed in order to expect upheaval movement in the road. In this procedure, the FLAC program which uses continuous modeling method was utilized, and new approach reflecting discontinuity developed toward the road with a ubiquitous joint model was tried to derive reliable analysis result.

• The Journal of Engineering Geology
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• v.21 no.2
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• pp.117-124
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• 2011

Soil deformations such as settlement, heaving and lateral flow have frequently happened on marine reclaimed soft grounds due to embankment filling or banking. The electrical resistivity survey was applied to investigate on ground surface such soil deformation without disturbance of ground. A test embankment was performed to assess soil deformation in marine reclaimed soft grounds, where was located at Sihwa area in western coast of Korean peninsula. The soft ground was composed of clayey sediments. After embankment filling, the boundary of soil deformation affected by the filling could be investigated with application of the electrical resistivity survey. The result of electric resistivity survey shows that the extent of deformation is about 5 m laterally to the southern direction of embankment and about 5~6 m vertically in depth, which is about 1-1.2 times of embankment height. This shows that the electric resistivity survey can be applied to interpret the ground deformation in a soft ground region.

• Journal of the Korean Wood Science and Technology
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• v.24 no.2
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• pp.61-70
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• 1996

침엽수재(針葉樹材)(Radiata pine, Pinus radiata)MDF와 활엽수재(闊葉樹材)(Rubber wood, Hevea brasiliensis)MDF 각 1종을 대상으로 MDF를 제조하기 전 원료(原料) 섬유(纖維)의 미세(微細) 구조(構造) 및 내부결합력 시험 후 MDF의 파괴면(破壞面)에서 섬유표면(纖維表面)에 접착제(接着劑)가 도포(塗布)된 형태를 주사전자현미경(走査電子顯微鏡)으로 관찰하였다. 원료 섬유는 침(針) 활엽수재(闊葉樹材) 모두 fiber twisting 및 shrinkage fold 등이 관찰되었다. 침엽수재(針葉樹材)의 경우는 유연벽공부(有緣壁孔部)에서 유연벽공(有緣壁孔)이 없는 부분에 비하여 shrinkage fold의 발생 빈도가 낮고 표면(表面) 박리(剝離)는 가도관(假導管) 중 벽공이 없는 부분에서 관찰되었다. 활엽수재(闊葉樹材) 목섬유(木纖維)는 침엽수재(針葉樹材)와 마찬가지로 shrinkage fold가 관찰되었으나 표면(表面) 박리(剝離)는 거의 관찰되지 않았다. 활엽수(闊葉樹) 섬유(纖維)에서는 벽공의 유무에 따른 shrinkage fold의 차이(差異)가 거의 관찰되지 않았는데 이는 목섬유(木纖維)가 침엽수(針葉樹) 가도관(假導管)보다 작은 단벽공(單壁孔)을 갖기 때문으로 생각된다. 또 방사유세포(放射柔細胞)와 가도관(假導管) 및 목섬유(木纖維)의 박리(剝離) 부분(部分)에는 융기부(隆起部)가 관찰되었다. 내부결합력 시험후 나타난 파괴면을 통하여 접착제 분포를 관찰한 결과 거의 모든 섬유(纖維)들이 접착제(接着劑)로 둘러싸여 있었으며 섬유(纖維)간 접착형태(接着形態)도 매우 다양하였다. 침활엽수재(針闊葉樹材)간에 강도(强度)의 차이는 있었지만 파괴(破壞) 형태(形態)는 큰 차이를 나타내지 않았다. 즉 침활엽수(針闊葉樹) 모두 접착층(接着層)이 아닌 섬유(纖維)에서 파괴(破壞)가 발생하였으며 섬유에서 박리(剝離)된, 세포벽(細胞壁)의 일부가 다른 섬유(纖維)의 표면(表面)에 남아있는 형태와 섬유(纖維) 표면(表面)에서 떨어져 나간 형태로 관찰되었다. 세포 구성이 단순한 침엽수(針葉樹) MDF에 비하여 유세포(柔細胞)와 도관(導管) 및 목섬유(木纖維)의 파편들이 활엽수(闊葉樹) MDF에서는 다양(多樣)하게 분포하였다.

• The Journal of Engineering Geology
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• v.15 no.4 s.42
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• pp.475-486
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• 2005

According to the inference results of formation process of the tectonic lineament, totally four events of subsidence including two events after upheaval of granite body and two events after sedimentation of unconsolidated sedimentary layer formed the macroscopic tensional lineament. The subsidence was occurred by tensional stress oriented ENE-WSW direction and compressional stress oriented NNW-SSE direction. The deeper distribution of tuff and unconsolidated sedimentary layer as much as 70-140m and that of granite as much as 50-500m at Hamdeok and Shinheung than those of the eastern and the western area around Hamdeok and Shinheong is due to the Hamdeok-Pyoseon Graben by three events of differential subsidence from Hamdeok to Pyoseon including Shinheung.

• Journal of Korea Water Resources Association
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• v.46 no.2
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• pp.139-153
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• 2013

For analyzing shallow-water flows over the uneven bottom, the HLLL scheme and the divergence form for bed slope source term (DFB) technique, respectively were applied to the flux gradient and the bottom gradient source terms in a finite-volume model for the shallow water equations. And also the model incorporated the volume/free-surface relationship (VFR) to consider the partially submerged cells (PSC). It was identified that a simpler version of the weighted surface-depth gradient method in the MUSCL was equivalent to the original one in the accuracy for 1D steady flows. It was verified that the flux gradient term and the bottom gradient source term were well-balanced exactly by the VFR for the 1D PSC. The VFR for the triangular PSC settled the problem which the governing equations were not well-balanced by the DFB technique for the 2D PSC. There were good agreements in simulations and experiments for 2D dam-break flows over a triangular sill and a round bump. In addition, the partial dam-break flow was successfully simulated for flooding of roughnesses in an irregular bottom as well as a sloping one. Therefore, this model is expected to be applied to the real river with uneven topography.

• Journal of the Korean Society for Railway
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• v.10 no.5
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• pp.576-581
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• 2007

The purpose of this study is to investigate changes in the forearm-muscle fatigue of a train driver operating the MasCon by using EMG (electromyogram) measurement technique. Train drivers usually use their forearm 4hours/day for normal operation. Accordingly, few different EMG signals of deltoid, biceps brachii, brachioradialis, flexor carpi ulnaris muscle of upper extremity have been measured and analyzed. The raw EMG Signals have been converted into median frequency using spectrum analysis. As the result, 80% of 10 subjects (real train drivers) showed that median frequency value of all four muscles has been reduced after 30 minutes of train operation. This results demonstrated that operating MasCon for 30 minutes could induce muscle fatigue.

• Journal of Korean Tunnelling and Underground Space Association
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• v.23 no.2
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• pp.107-118
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• 2021

Due to the acceleration of road construction, the number and extension of tunnels are increasing every year. A lot of research has been done on the collapse of tunnels, but research on the invert heaving is insufficient. Therefore, in this study, a sensitivity analysis was performed using a geotechnical general-purpose program to analyze the effect of the invert curvature of a tunnel excavated on the soft ground. As a result, it was quantitatively confirmed that the stability of a tunnel was increased as the curvature of the tunnel invert was increased so that the safety factor was calculated to be large regardless of the ground conditions and the thickness of the support. In addition, it was confirmed that the stability of the tunnel was increased by reducing the convergence of the tunnel and the maximum bending stress supported by shotcrete. Therefore, when a tunnel is excavated on soft ground, it is believed that applying a curvature to the invert will increase the stability of the tunnel.

• Journal of the Korean Geotechnical Society
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• v.38 no.11
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• pp.107-118
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• 2022

The social need for stable hydrogen storage technologies that respond to the increasing demand for hydrogen energy is increasing. Among them, underground hydrogen storage is recognized as the most economical and reasonable storage method because of its vast hydrogen storage capacity. In Korea, low-depth hydrogen storage using artificial protective structures is being considered. Further, establishing corresponding safety standards and ground stability evaluation is becoming essential. This study evaluated the hydro-mechanical behavior of the ground during a hydrogen gas leak from a low-depth underground hydrogen storage facility through the HM coupled analysis model. The predictive reliability of the simulation model was verified through benchmark experiments. A parameter study was performed using a metamodel to analyze the sensitivity of factors affecting the surface uplift caused by the upward infiltration of high-pressure hydrogen gas. Accordingly, it was confirmed that the elastic modulus of the ground was the largest. The simulation results are considered to be valuable primary data for evaluating the complex analysis of hydrogen gas explosions as well as hydrogen gas leaks in the future.

• Journal of The Geomorphological Association of Korea
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• v.17 no.2
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• pp.1-13
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• 2010

The technique of mountain ordering developed by Yamada(1999) has been tested to two small islands (Namhaedo: 301km², Geojedo: 378km²). The results and experiences above were extended and applied to the whole area of the southern part of Korean Peninsula. Three areas such as Seorak-Taebaek Mountains, Jiri-Deogyu Mountains, and Youngnam Alps are identified as the highest, 5th order mountains. 10 areas are classified as the 4th order and 87 areas as the 3rd order. It is suggested that the 5th order mountains are related to the axis of uplift and the 4th and 3rd order mountains have the same direction (NE-SW) as that of the secondary mountain systems in the Korean Peninsula. The logarithmic values of number, area, and relative altitude of the ordered mountains have the linear relationship with the order, as the laws of stream order. The several mountains which are not included in the existing mountain systems could be identified among the ordered mountains, and those mountains could be used as the basis to understand the geological structure of the Korean Peninsula. Most of the National Parks and the Provincial Parks are distributed on the 3rd, 4th, 5th order mountains. It is especially confirmed that the Songnisan National Park take a role to link the Seorak-Taebaek Mountains and Jiri-Deogyu Mountains as a important ecological axis. Therefore, it would be validated that the technique of mountain ordering has the practical values as well as the geomorphological significances.