• The Journal of Internal Korean Medicine
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• v.45 no.2
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• pp.270-277
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• 2024

Objectives: This study identified the effects of Korean medicine treatment on a patient with alcohol-associated cirrhosis. Methods: A 50-year-old male with alcohol-associated cirrhosis was treated with Cheongganhaeju-tang from 10 November 2023 to 18 January 2024 to reduce fatigue, dyspepsia, anorexia, and weight loss and to improve laboratory findings, such as liver enzymes. We observed changes in the patient's symptoms and laboratory findings during a treatment period of approximately 2 months. Results: With Cheongganhaeju-tang treatment, serum levels of liver enzymes remained stable, clinical symptoms improved, and alcohol cravings decreased. Conclusion: This case points to Cheongganhaeju-tang as a therapeutic option to manage alcohol-associated cirrhosis.

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.4
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• pp.167-167
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• 2021

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.4
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• pp.168-168
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• 2021

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.3
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• pp.246-256
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• 2009

Purpose: To report the effect of oriental medicine on 2 patients with secondary amenorrhea diagnosed as hypothalamic-pituitary failure. Methods: The patients who had secondary amenorrhea were treated with the oriental medical treatments such as herbal medication, herbal acupuncture and moxibustion therapy, and so forth. Results: After the oriental medical treatments, the patients could have their periods again, their menstrual condition was improved. Conclusion: This case report shows that the oriental medical therapy is effective for treating secondary amenorrhea diagnosed as hypothalamic-pituitary failure.

• Herbal Formula Science
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• v.29 no.4
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• pp.321-329
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• 2021

This case study reports the effects of complex Korean medicine treatment, including Nangan-jeon, on Lambert-Eaton myasthenic syndrome (LEMS) accompanied by chronic constipation and abdominal pain as the main symptoms. A 39-year-old woman diagnosed with LEMS with major symptoms, including chronic constipation and acute abdominal pain, received Western treatment. The treatment efficacy was weak and symptoms recurred, so the patient received outpatient treatment and 13 days of hospitalization for active Korean medicine treatment, including Nangan-jeon. During outpatient treatment and hospitalization, defecation frequency and the numeric rating scale (NRS) for abdominal pain and abdominal cold feeling were measured. The NRS for abdominal pain and cold decreased from 8 at admission to 3 and 0, respectively, at discharge. Defecation frequency increased significantly from once or twice a month to once every 2-3 days during hospitalization. This study results that complex Korean medicine treatment, including Nangan-jeon may be useful for treating patients who mainly complain of autonomic neurological symptoms, among patients diagnosed with LEMS. In addition, it is believed that it could be basic data applicable to more LEMS patient treatment cases.

• Herbal Formula Science
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• v.29 no.1
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• pp.33-44
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• 2021

Renal ischemia-reperfusion injury(IRI), an important cause of acute renal failure (ARF), cause increased renal tubular injury. Jesaeng-sinkihwan (JSH) was recorded in a traditional Chines medical book named "Bangyakhappyeon (方藥合編)". JSH has been used for treatment of diabetes and glomerulonephritis with patients. Here we investigate the effects of Jesaeng-sinkihwan (JSH) in a mouse model of ischemic acute kidney injury. The animals model were divided into four groups at the age of 8 weeks; sham group: C57BL6 male mice (n=9), I/R group: C57BL6 male mice with I/R surgery (n=9), JSH Low group: C57BL6 male mice with surgery + JSH 100 mg/kg/day (n=9) and JSH High group: C57BL6 male mice with surgery + JSH 300 mg/kg/day (n=9). Ischemia was induced by clamping the both renal arteries during 25 min, and reperfusion was followed. Mouse were orally given with JSH (100 and 300 mg/kg/day during 3 days after surgery. Treatment with JSH significantly ameliorates creatinine clearance(Ccr), Creatinine (Cr) and blood urea nitrogen(BUN) in obtained plasma. . Treatment with JSH reduced kidney inflammation markers such as Neutrophil Gelatinase Associated Lipocalin (NGAL) and kidney injury molecule-1 (KIM-1). JSH also reduced the periodic acid schiff (PAS) staining intensity and picro sirius red staining intensity in kidney of I/R group. These findings suggest that JSH ameliorates tubular injury including renal dysfunction in I/R induced ARF mouse.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.13 no.2
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• pp.11-21
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• 2018

Objectives : To evaluate the evidence for effectiveness of Chuna manual therapy, for cervicogenic dizziness Methods : We conducted a search across 6 electronic databases to find all randomized controlled clinical trials(RCTs) that discuss Chuna manual therapy till September 2018. Results : 7 RCTs were selected for our inclusion criteria. The systematic review showed positive results for using Chuna manual therapy, for treating cervicogenic dizziness. Conclusions : Our systematic review found that effectiveness Chuna manual therapy for cervicogenic dizziness. However, our systematic review had several limited evidence. We recommend an additional research to test the effectiveness of Chuna manual therapy.

• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.445-510
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• 1994

• Journal of Korean Medical classics
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• v.35 no.4
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• pp.1-9
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• 2022

Objectives : This study aims to increase efficiency of the prescription similarity analysis method that uses drug composition ratio. Methods : The controlled experiment compared result generation time, generated data quantity, and accuracy of results between previous and new analysis method on the 12,598 formulas and 61 prescription groups. Results : The control group took 346 seconds on average and generated 768,478 results, while the test group took 24 seconds and generated 241,739 results. The test group adopted a selective calculation method that only used overlapping data between two formulas instead of analyzing all number of cases. It simplified the data processing process, reducing the quantity of data that is required to be processed, leading to better system speed, as fast as 14.47 times more than previous analysis method with equal results. Conclusions : Efficiency for similarity analysis could be improved by reducing data span and simplifying the calculation processes.

• Herbal Formula Science
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• v.30 no.4
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• pp.351-361
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• 2022

Objectives : The purpose of this study is to report the clinical effect of herbal medicine decoction on COVID-19 symptoms remaining after administering Western medicine and worsening eczema during the COVID-19 prevalence period in patients with chronic eczema. Methods : The two chronic eczema patients suffering from COVID-19 symptoms and worsening eczema received a series of herbal medicine decoction for treatment. The effectiveness of treatment was evaluated by VAS, NRS, EASI, PASI, DLQI, photography and subjective evaluation of the patient's improvement of symptoms. Results : After treatment, all symptoms of COVID-19 disappered and aggravated eczema lesions were remarkably improved in both cases. Compared to its peak, the first case shows that PASI improved by 88% and DLQI by 44%. According to photo and symptom changes, the size of the affected area of facial acne and lip eczema was decreased. The second case shows that EASI improved by 43% and DLQI by 65%. According to photo and symptom changes, redness, rash were stopped and pruritus was decreased. Conclusion : This study suggests that herbal medicine could induce effectiveness on both COVID-19 symptoms as well as chronic eczema.