• Journal of Digital Convergence
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• v.17 no.10
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• pp.359-372
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• 2019

Metabolic syndrome is deeply related with risks of chronic disease and mortality. Furthermore, the metabolic syndrome disorder in childhood and adolescence usually tends to lead to a number of cardiovascular disease in the stage of adulthood. In this sense, metabolic syndrome needs to be investigated seriously. The purpose of this study is therefore to prove the relationship between dietary habits(high carbohydrate, high calorie) and metabolic syndrome among adolescents. We also aim to clarify the relationship between emotional factors perceived by adolescents and metabolic syndrome. Our empirical results based on KNHANES dataset significantly demonstrates that the HDL-cholesterol is a decisive factor for the diagnosis of metabolic syndrome disorder. Additionally, emotional experience factors such as stress also show significant effects in difference of adolescents' metabolic syndrome.

• Journal of Nutrition and Health
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• v.41 no.6
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• pp.510-517
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• 2008

This study was conducted to investigate the prevalence of metabolic syndrome(MS) and characteristics of nutrient intake in MS subjects by gender and age. The subjects were 957(447 men and 510 women) who visited medical center for regular medical check-up. The diagnosis of MS subjects was adapted from NCEP-ATPIII with blood glucose, cholesterol, triglycerides, and blood pressure and Aisa-Pacific definition with waist-circumference. Anthropometric and biochemical measurements were practiced, then the nutrient intake analysis was assessed through the 24-hour recall method. The MS prevalence of all subjects was 10.3% in average -17% in men and 4.5% in women, respectively. The energy intake in MS group was 2,047.1 kcal and 1,699.5 kcal for normal group, showing significantly higher in MS compared to normal subjects. For intakes of animal fat, cholesterol, and sodium, MS group were significantly higher than normal group. In respect of gender, men subjects of MS group showed significantly higher nutrient intakes than normal group for energy, fat, and cholesterol. Women subjects of MS group showed higher intakes for energy, carbohydrate, and protein. For 30s, MS group showed higher intakes of energy, animal fat, and cholesterol than normal group. Fat and cholesterol for 40s and energy, carbohydrate, vegetable fat for 50s, MS group showed significantly higher intakes than normal group. In summary, MS group showed higher intakes of energy, animal fat, cholesterol, and sodium than normal group.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.3934-3943
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• 2015

This study was conducted to investigate the incidence rate of metabolic syndrome, and the related factors were examined. 620 persons who had participated in both initial and second survey were selected. Initial survey was performed at the year of 2006 and second survey was performed at the year of 2010. Among them, 460 persons who didn't initially have a metabolic syndrome were selected as the final study subjects. They were classified into 2 categories; stationary normal group (352, 76.5%), and metabolic syndrome incidence group (108, 23.5%). The incidence rate of metabolic syndrome for the subjects was 25.2 per 1,000 person years. Sex, obesity, and smoking had significant effect on the incidence of metabolic syndrome. In multiple logistic regression analysis,after controlling variables, obesity index was found to be major factor in the incidence of metabolic syndrome. The risk of metabolic syndrome was increased by overweight or obesity. The strategy to control body weight should be emphasized for prevention of metabolic syndrome.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.390-399
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• 2014

This research was conducted to determine the effects on knowledge about menstruation, coping with menstruation, menstrual symptom of middle school students after they received Health Behavior-based PMS Intervention Education. By using a non-equivalent control group pretest and posttest design, the experiment was conducted with a test group of 31 students and a control group of 33 students. There were statistically significant increases in knowledge about menstruation and coping with menstruation in the experimental group compared to the control group. From these finding, Health Behavior-based PMS Intervention Education for middle school students is effective and the development of such PMS Intervention Education is desirable in terms of health care.

• The Journal of the Korea Contents Association
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• v.21 no.8
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• pp.662-674
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• 2021

Metabolic syndrome is closely associated with cardiovascular disease, there is increasing attentions in prevention of metabolic syndrome through prediction. The aim of this study was to systematically review the literature by collecting, analyzing, and synthesizing articles of predicting metabolic syndrome in Koreans. For systemic review, data search was conducted on Global journals Pubmed, WoS and domestic journals DBPia, KISS published in 2011-2020 year. Three keyword 'Metabolic syndrome', 'predict', and 'korea' were used for searching under AND condition. Total 560 articles were searched and the final 22 articles were selected according to the data selection criteria. The most useful variable was WHtR(AUC=0.897), most frequently used analysis method was logistic regression(63.6%), and most accurate analysis method was XGBOOST(AUC=0.879) for predicting metabolic syndrome. Prediction accuracy was slightly improved when sasang constitution types was used. Based on the results of this study, it is believed that various large-scale longitudinal studies for the prediction and management of the Metabolic syndrome in Korean should be followed in the future.

• The Journal of the Korea Contents Association
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• v.14 no.1
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• pp.326-336
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• 2014

The purpose of this study was to assess the association between habitual snoring and metabolic syndrome in the Korean population and to evaluate it's possible gender variations. The study subjects were 2,007 volunteers aged 40-69 years who participated in regular health check-ups(male:434, female:1,573) from May 2012 to December 2012. Standard interviews, anthropometrics and biochemical studies were conducted. Habitual snoring was defined as snoring more than 4 days per week. The prevalence of metabolic syndrome in our sampling pool was 17.4% (male: 20.7%, female: 16.5%), and this increased with age. After adjusting for age, smoke and alcohol consumption, sleep duration, regular exercise, the odds ratio of metabolic syndrome and it's components were increased significantly by habitual snoring. HDL-cholesterol, blood sugar, waist size were significantly higher in women, but not significantly higher in men.

• Childhood Kidney Diseases
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• v.5 no.2
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• pp.87-99
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• 2001

Purpose: We studied to find out apo-E genotype polymorphism in minimal change nephrotic syndrome(MCNS) and IgA nephropathy(IgAN) and to determine the relationship between apo-E genotype and clinical course of MCNS. Materials and Method: 43 MCNS patients and 15 IgAN patients were examined for apo-E polymorphism. 50 healthy blood donors were examined for apo-E genotype as control. Genomic DNA was prepared front peripheral blood leukocytes according to standard procedures. Results: As compared with control group, e4 allele frequency was significantly increased in MCNS (p<0.01). However, in IgAN e2 allele frequency, however, was 2.6 times higher than normal control (P<0.01). The frequency of e4 allele of frequent relapser group was 4.6 times higher than normal control and was 2 times higher than infrequent relapser group. Conclusion: We think that apo-E typing might be one of the parameters, which should be considered to predict the course of MCNS in children. MCNS with risky HLA profile and E4/4 genotype could indicate the need for a longer steroid administration. And apo-E genotype needs to be considered for the evaluation of therapeutic responses to other drugs. (J, Korean Soc Pediatr Nephrol 2001 ; 5 : 87-99)

• Journal of the Korean Applied Science and Technology
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• v.40 no.3
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• pp.462-475
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• 2023

This study is descriptive research to identify the effect of COVID-19 stress on premenstrual syndrome in female college students and the mediating effect of depression and coping with premenstrual syndrome. The data were collected through an on-line survey for 20 days from November 11 to November 30, 2021, targeting female college students attending C College located in S city. As a result of analyzing a total of 161 data, COVID-19 stress was positively correlated with premenstrual syndrome(r=.383, p<.001) and depression(r=.436, p<.001), and coping with premenstrual syndrome had a positive correlation only in premenstrual syndrome(r=.190, p=.016). As a result of verifying the mediating effect of depression and coping with premenstrual syndrome between COVID-19 stress and premenstrual syndrome, COVID-19 stress had a significant direct effect on premenstrual syndrome(β=4.907, p=.002), and depression(β=6.780, p<.001), and depression had a significant direct effect on premenstrual syndrome(β=.383, p=<.001), coping with premenstrual syndrome had a direct effect on premenstrual syndrome(β=4.292, p=.030) respectively. The indirect effect of verifying the mediating effect in the relationship between COVID-19 stress and premenstrual syndrome confirmed that there was a statistically significant effect only in the path via depression(95% CI, 1.282 to 4.140). Therefore, it is necessary to develop an intervention strategy to reduce depression and alleviate premenstrual syndrome symptoms by controlling related stress, such as COVID-19 stress, in preparation for the outbreak of new infectious diseases and pandemic situations such as COVID-19.

• Clinical and Experimental Pediatrics
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• v.52 no.11
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• pp.1260-1266
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• 2009

Purpose : Idiopathic nephrotic syndrome (NS) can be clinically classified as steroid-sensitive and steroid-resistant. The detailed mechanism of glucocorticoid action in NS is currently unknown. Methods : In this study, we investigated 3 known single nucleotide polymorphisms (SNPs) (ER22/23EK, N363S, and BclI) of the glucocorticoid receptor gene (the NR3C1 gene) in 190 children with NS using polymerase chain reaction-restriction fragment length polymorphism and analyzed the correlation between the genotypes and clinicopathologic features of the patients. Results : Eighty patients (42.1%) were initial steroid nonresponders, of which 31 (16.3% of the total) developed end-stage renal disease during follow-up. Renal biopsy findings of 133 patients were available, of which 36 (31.9%) showed minimal changes in NS and 77 (68.1%) had focal segmental glomerulosclerosis. The distribution of the BclI genotypes was comparable between the patient and control groups, and the G allele frequencies in both the groups were almost the same. The ER22/23EK and N363S genotypes were homogenous as ER/ER and NN, respectively, in all the patients and in 100 control subjects. The BclI genotype showed no correlation with the NS onset age, initial steroid responsiveness, renal pathologic findings, or progression to end-stage renal disease. Conclusion : These data suggested that the ER22/23EK, N363S, and BclI SNPs in the NR3C1 gene do not affect the development of NS, initial steroid responsiveness, renal pathologic lesion, and progression to end-stage renal disease in Korean children with NS.

• Journal of the Korea Convergence Society
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• v.9 no.9
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• pp.363-369
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• 2018

The purpose of this study was to perform exercise program for patients with borderline hypertension and hypertension. And the change of the metabolic syndrome index. This study was performed for 15 weeks on borderline hypertension, hypertension patients. 28 subjects participated in the exercise program for 40 minutes, three times a week for 15 weeks. The following conclusions were obtained. First, there was a significant correlation between the prevalence of metabolic syndrome before and after the exercise program. Second, there were significant differences in body weight, muscle mass, fat mass, BMI, waist circumference, diastolic blood pressure, and blood sugar before and after 15 weeks of exercise program. This can lead to improved metabolic syndrome indicators in hypertensive patients with a muscle extension exercise program.