• The Journal of the Society of Stroke on Korean Medicine
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• v.13 no.1
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• pp.126-133
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• 2012

Object : The Purpose of this study is to report the clinical application of Korean traditional medicine on gait disturbance with arteriosclerosis of lower limbs. Methods : The patient in this case had been already treated by anticoagulation and varicose vein operation for subsiding and improving intermittent claduication and rest pain, but these methods didn't work on the patient. Although the patient was classified as TASC-II D, bypass operation couldn't be treated because of heart disease of the patient. We treated Korean traditional medicine such as acupuncture, moxibustion, Danggwisaeyeoktang. Results : After treatment, peak walking time was increased, rest pain occurrence was decreased and going up and down the stairs was improved. Conclusions : According to this study, Korean traditional medicine such as acupuncture, moxibustion, Danggwisaeyeoktang is effective for the cure of intermittent claudication and rest pain caused by arteriosclerosis of lower limbs.

• Journal of the Korean Society of Physical Medicine
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• v.18 no.2
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• pp.93-101
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• 2023

PURPOSE: The Western Ontario and McMaster Universities Arthritis (WOMAC) index has been used to measure the outcome of total knee replacement (TKR), but studies on its reliability and validity are limited. The present study examined the reliability and validity of this index for patients with knee osteoarthritis who underwent TKR. METHODS: Seventy-one inpatients and outpatients who underwent bilateral TKR for knee osteoarthritis were included in this study. The pain assessment scale and WOMAC index were used to evaluate the participants every two weeks to examine the test-retest reliability, internal consistency, and construct validity. RESULTS: The test-retest reliability scores for pain, stiffness, and physical function were .75-.92, .85-.90, and .75-.95, respectively. The corresponding intraclass correlation coefficients were .75-.88, .76-.88, and .71-.95, respectively. The internal consistency score in the first and second examinations was .92. Furthermore, the construct validity scores for pain, stiffness, and physical function were .83, .41, and .58, respectively. CONCLUSION: The application of the WOMAC index in patients who underwent TKR showed high test-retest reliability and internal consistency with the use of the WOMAC index and good validity with the use of the pain assessment scale.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.01a
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• pp.107-108
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• 2023

기업 및 공공기관의 클라우드 서비스 도입이 확산되면서 업무 시스템에 대한 보안 요구사항이 변화하고 있다. 기존에는 보호해야 할 정보자산이 물리적으로 외부와 분리된 내부 공간에 집중되었다면 클라우드 환경에서는 자산의 분포 범위가 넓어지면서 내부와 외부의 경계가 모호해진다. 따라서 경계 기반의 전통적인 보안 방식은 클라우드 기반 업무환경에 적합하지 않으며 정보 서비스를 이용하는 전 주기에서 암묵적인 신뢰를 배제하고 지속적으로 검증을 수행하는 제로 트러스트 기반의 업무 시스템 운영이 필요하다. 본 논문에서는 스토리지 클라우드 서비스인 아마존 웹 서비스 S3(Simple Storage Service)에 대하여 제로 트러스트 모델을 설계하고, 직접 서비스를 운영하며 제안된 제로 트러스트 모델의 안전성을 검증한다. 제로 트러스트 모델은 스토리지에 접근하는 사용자에 대한 인증 및 식별 기술, 스토리지 암호화 기술, 암호화 키 관리 기술을 활용하여 설계하였으며 제로 트러스트 기술 적용 시, 스토리지 보안성이 향상되는 것을 실제 서비스 운영을 통한 실험을 통해 확인하였다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2024.01a
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• pp.123-125
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• 2024

다크웹(Dark Web)은 마약, 불법 촬영물, 해킹, 무기 등 불법 콘텐츠의 공유 및 거래가 이루어지는 인터넷 영역으로서 최근에는 소셜미디어와 연계된 형태로 범죄 양상이 변화하고 있다. 본 논문에서는 최근 국내 외 사회 문제로 대두되고 있는 마약 범죄를 추적하기 위한 다크웹 수사 기술로서 다크웹 사용자를 소셜미디어로 유인하는 마약 정보 수집체계를 개발한다. 먼저 미국 마약단속국에서 공개한 대표적인 마약 용어 3개의 표준어 및 은어를 검색 키워드로 사용하여 마약 관련 다크웹을 수집하고, 수집된 다크웹을 크롤링하여 소셜미디어 계정 링크를 추출한다. 본 논문에서는 다양한 소셜미디어 중, 트위터 및 텔레그램 접속 링크를 수집하였으며 실험 결과, 접속 가능한 총 54개 다크웹 도메인의 9,046개 웹 페이지에서 트위터 유인 링크 567개, 텔레그램 유인 링크 118개를 추출하였다.

• Journal of Korean Medicine Rehabilitation
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• v.34 no.2
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• pp.173-180
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• 2024

Objectives The purpose of this study is to report the effects of Korean medicine treatment on tibia, fibula, and patellar fractures with sequelae of poliomyelitis. Methods A 64-year-old male patient was treated with acupuncture, herbal medicine, cupping, moxibustion, and exercise treatment for 59 days after open reduction and internal fixation and tension band wiring surgery. The effects were evaluated using a visual analog scale (VAS), manual muscle testing (MMT), range of motion (ROM), Western Ontario and McMaster Universities (WOMAC), and EuroQol-5 dimension (EQ-5D) index. Results After treatment, VAS decreased from 7 to 2. MMT, ROM, WOMAC, EQ-5D and walking ability were improved. Conclusions This case study suggests that Korean medicine treatment could be effective for tibia, fibula, patellar fractures in patients with sequelae of poliomyelitis.

• Journal of Conservation Science
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• v.35 no.3
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• pp.209-216
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• 2019

Lead isotope ratios in horse-shaped bronze buckles excavated from the Songjeol-dong site in Cheongju and the mid-western region of the Korean Peninsula have been determined by thermal ionization mass spectrometry. The lead isotope ratios of the samples with data provenance were plotted in zone 3 of the South Korean galena map. The results indicated that the horse-shaped bronze buckles could be made using galena located in the same area as the archaeological site. These results can be used as basic data for comparison purposes in future studies on the manufacturing technology and provenance of bronze artifacts.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.4
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• pp.333-340
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• 2021

In this study, Rosa multiflora was sampled through extraction, concentration, and freezing. The antioxidant efficacy of a mixture of R. multiflora extract and ascorbic acid was compared with a single ascorbic acid. The purpose of this study was to analyze the antioxidant efficacy through the synergistic effect of R. multiflora extract and ascorbic acid. The experiment measured electron donating ability, ABTS+ radical scavenging, SOD-like activity, xanthine oxidase inhibition activity, reducing power, FRAP, polyphenolic content measurement, and flavnoid content measurement. As a result, the complex showed higher antioxidant activity than the control group (ascorbic acid) in the electron donating ability test and the xanthine oxidase inhibitory activity test. In the case of the flavonoid content experiment, it was confirmed that RMW+A (272.1 mg QE/g), RME+A (90.6 mg QE/g), and RMW+A (79.4 mg QE/g) at a concentration of 100 ㎍/mL had a higher flavonoid content than the control group (19.0 mg QE/g). Therefore, the extract and ascorbic acid complex exhibited a synergistic effect compared to the single use. Therefore, it is thought that this complex will contribute to product stabilization and skin aging inhibition when used in antioxidant cosmetics.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.4
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• pp.353-360
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• 2021

In this study, the skin whitening and anti-wrinkle activity of Abelmoschus manihot (A. manihot) flowers were evaluated as a cosmetic material. A. manihot flowers were extracted using water and 70% ethanol. Tyrosinase inhibitory activity was evaluated to increase concentration-dependent inhibitory activity in both water (AMW) and 70% ethanol extracts (AME), and was found to inhibit melanin biosynthesis at concentrations that did not affect survival in B16F10 cell lines at 10, 25, 50, 75, and 100 ㎍/mL. As a result of measuring the anti-wrinkle effectiveness of A. manihot flowers, 70% ethanol extract (AME) showed higher anti-wrinkle activity than water extract (AMW). Through the results of this study, it is considered that the A. manihot flower extract can be used as a functional cosmetic material with whitening and anti-wrinkle activity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.6
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• pp.247-251
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• 2022

This study is to show the clinical effect of Korean medicine integrated treatment for medial collateral ligament tear with bone contusion by traffic accident. The patients were treated using Korean medicine integrated treatment including acupunture, pharmacoacupunture and herbal medication. The effect of treatment was measured by Western Ontario and McMaster Universities Arthritis Index (WOMAC), EuroQol-5 Dimension Index (EQ-5D) and Numeric Rating Scale (NRS). After treatment, case 1 improved WOMAC from 94 to 24, EQ-5D from -0.056 to 0.72, and NRS from 10 to 2. Case 2 showed an improvement in symptoms from WOMAC 91 to 14, EQ-5D from 0.077 to 0.862, NRS from 10 to 2.5. In addition, as a result of follow-up about 5 months after each onset, case 1 showed a further improvement with WOMAC 0, EQ-5D 0.95 and case 2 WOMAC 7, EQ-5D 0.913. These results suggest that Korean medicine integrated treatment might be a possible therapeutic option for the medial collateral ligament tear with bone contusion by traffic accident.

• The Korea Journal of Herbology
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• v.38 no.2
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• pp.17-26
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• 2023

Objectives : A persistent inflammatory response can cause diseases such as fibrosis, cancer, and allergies. This study aimed to investigate the anti-inflammatory activity of Curcumae longae Rhizoma and Cinnamomi Ramulus Mixture (CCM) in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Methods : The total polyphenol and flavonoid contents of CCM were confirmed through an in vitro experiment. Also, radical scavenging activities of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and Hydroxyl were confirmed. Moreover, ferric reducing antioxidant power (FRAP) activity were confirmed. After, CCM (50, 100, and 200 ㎍/mL) were applied to 0.1 ㎍/mL LPS-stimulated RAW264.7 cells. The levels of nitric oxide (NO) and pro-inflammatory cytokines in the supernatant fraction were determined. Also, the expressions of mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) pathways were detected using Western blot. Results : As a result of in vitro experiments, there was an excellent antioxidant activity in CCM-treated cells. In addition, in RAW264.7 cells stimulated with LPS, the increased NO level was inhibited in a concentration-dependent manner by the treatment of CCM. In addition, inflammatory cytokines production were significantly inhibited in a concentration-dependent manner in CCM-treated group. CCM treatment significantly decreased the protein expressions of MAPKs. Moreover, the expressions of NF-κBp65 and cyclooxygenase-2 (COX-2) were significantly decreased when 200 mg/kg of CCM was applied, and phospho-inhibitor of nuclear factor kappa B-α (p-IκBα) and inducible nitric oxide synthase (iNOS) were significantly decreased at all concentrations treated with CCM. Conclusion : Our findings show that CCM exhibited excellent antioxidant activity and exhibited superior anti-inflammatory effect through the MAPKs and NF-κB pathways in LPS-stimulated RAW 264.7 macrophages.