• Title/Summary/Keyword: 단위정상법

Search Result 68, Processing Time 0.033 seconds

Study on Overcoming Interference Factor by Automatic Synthesizer in Endotoxin Test (내독소 검사에서 자동합성장치에 따른 간섭요인 극복에 대한 연구)

  • Kim, Dong Il;Kim, Si Hwal;Chi, Yong Gi;Seok, Jae Dong
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.16 no.2
    • /
    • pp.3-6
    • /
    • 2012
  • Purpose : Samsung medical ceter shall find a cause of the interference factor and suggest a solution for it. Materials and Methods : A sample of $^{18}F$-FDG, radioactive pharmaceuticals produced by TRACERlab MX and FASTlab synthesizer. Gel-clot method uses Positive control tube and single test tube. Kinetic chromogenic method uses ENDOSAFE-PTS produced by Charles River. Results : According to Gel clot method of Endotoxin Tests at FASTlab, both turbidity and viscosity increased at 40-fold dilution and Gel clot was detected. In case of TRACERlab MX, Gel clot was detected in most of samples but intermittently not in a few of them. When using ENDOSAFE-PTS, sample CV (Coefficient of Variation) of FASTlab is 0% at all dilution rates whereas spike CV is 0% at 1-fold dilution, 0~35% at 10-fold, 3.6~12.9% at 20-fold, 5.2~7.1% at 30-fold, 1.1~17.4% at 40-fold, spike recovery; 0% at one-fold, 25 ~ 58% at 10-fold, 50 ~ 86% at 20-fold, 70~92% at 30-fold, and 75~120% at 40-fold. Sample CV of TRACERlab MX, is 0% at all dilution rates whereas spike CV is 1.4~4.8% at one-fold dilution, 0.6~19.9% at 10-fold, spike recovery; 35~72% at one-fold dilution and 77~107% at 10-fold. Conclusion : Gel clot does not seem to occur probably to H3PO4 which engages in bonding with Mg2+ion contributing gelation inside PCT. Dilution which is identical to reducing the amount of H3PO4, could remove interfering effects accordingly. Spike recovery was obtained within 70~150% - recommended values of supplier - at 40-fold dilution even in kinetic chromogenic method.

  • PDF

Characterization of Thermal Properties for Glass Beads - Rubber Mixture (글라스 비즈 - 고무 분말 혼합물의 열전달 특성 연구)

  • Lee, Jung-Hwoon;Yun, Tae-Sup;Evans, T. Matthew
    • Journal of the Korean Geotechnical Society
    • /
    • v.27 no.11
    • /
    • pp.39-45
    • /
    • 2011
  • This study presents the thermal behaviors of glass beads-rubber mixtures depending on the volumetric fraction of each constituent and relative size between them. The transient plane source method is used to measure the effective thermal conductivity of mixtures. The discrete element method (DEM) and the thermal network model are integrated to investigate the particle-scale mechanism of heat transfer in granular packings. Results show that 1) the effective thermal conductivity decreases as the rubber fraction increases, and 2) the relative size between two solid particles dominates the spatial configuration of inter-particle contact condition that in tum determines the majority of heat propagation path through particle contacts. For the mixtures whose volumetric fraction of rubber is identical, the less conductive materials (e.g., rubber particles) with a large size facilitate heat transfer in granular materials. The experimental results and particle-scale observation highlight that the thermal conduction behavior is dominated not only by the volumetric fraction but also the spatial configuration of each constituent.

Analysis on the Problems in Carrying Out Homework Assignments in a Middle Class Engineering College (중위권 공과대학에서 학생 과제물 수행에 대한 문제점 분석)

  • Baek, Hyun-Deok;Park, Jin-Won
    • Journal of Engineering Education Research
    • /
    • v.12 no.3
    • /
    • pp.129-136
    • /
    • 2009
  • This paper is on the analysis of the present situation in carrying out homework assignments of the students in the college of Science and Technology, Hongik University. Our survey confirmed that the purpose of the assignments was not satisfactorily achieved, because only a few students solve the problems by their own efforts and most of the other students just copied their peers' work. The reason for this problem was analysed based on the result of questionnaire for the professors and students. Possible solutions for the problem is proposed, such as providing sufficient number of teaching assistants and changing instruction strategy, reflecting the significance of homework assignments in the learning process. As one of the probable solutions, a team-based assignment is proposed, and expected and observed positive results were discussed.

Improved X-ray Center Beam Alignment Evaluation Method (개선된 X선 중심선속정렬평가 측정법)

  • Choi, Seokyoon
    • Journal of the Korean Society of Radiology
    • /
    • v.14 no.6
    • /
    • pp.827-832
    • /
    • 2020
  • X-ray equipment, which is frequently used in radiology and treatment, is the most common and most used equipment in clinical practice. Equipment must provide accurate information to patients through continuous quality control. In case of manual quality control measurement, reproducibility may be poor and there may be a problem with reliability of evaluation results. In this study, an automated program was developed and attempted to measure how much the central ray between the focus of the X-ray tube and the variable aperture of the diagnostic X-ray generator used in clinical practice coincides. As a result of the experiment, it succeeded in calculating the coordinates of the two center points, and the distance between the two points was calculated in pixels and applied to the judgment and the automatic judgment value for whether the center line coincidence is within the normal angle or the abnormal angle is presented. The results of this study are considered to be very helpful in the quality control of the X-ray apparatus.

The Crystal and Molecular Structure of Cholesteryl Pentanoate (콜레스테릴 펜타노에이트의 결정 및 분자구조)

  • An, Jung Tae;Park, Yeong Ja
    • Journal of the Korean Chemical Society
    • /
    • v.34 no.1
    • /
    • pp.1-9
    • /
    • 1990
  • Cholesteryl pentanoate $(C_{32}O_2H_{54})$ is orthorhombic, space group $P2_12_12_1$, with a = 21.930(3), b = 21.404(3), c = 6.419(5) $\AA$, Z = 4, V = 3012.8(5)$\AA$$^3$, $D_c$ = 1.04 g$cm^{-3}$, ${\lambda}(Mo\; K{\alpha}$ = 0.71069 $\AA$, $\mu$ = 0.58 $cm^{-1}$, F(000) = 1048, T = 298, R = 0.086 for 1502 unique observed reflections with I > 1.0 $\sigma$ (I). The structure was solved by direct methods and refined by cascade diagonal least-squares refinement. The C-H bond lengths and the methyl groups are fixed and refined as their ideal geometry. A comparison with other cholesteryl esters gives normal structure for the tetracyclic ring, while the tail regions of the side chain and the ester group which stands on end, show a variation from their normal values, presumably due to thermal effects. The molecules are stacked together by non-bonded van der Waals forces with the shortest intermolecular distance of 3.529 $\AA$.

  • PDF

Target Speech Detection Using Gaussian Mixture Model of Frequency Bandwise Power Ratio for GSC-Based Beamforming (GSC 기반 빔포밍을 위한 주파수 밴드별 전력비 분포의 혼합 가우시안 모델을 이용한 목표 음성신호의 검출)

  • Chang, Hyungwook;Kim, Youngil;Jeong, Sangbae
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.19 no.1
    • /
    • pp.61-68
    • /
    • 2015
  • Noise reduction is necessary to compensate for the degradation of recognition performance by various types of noises. Among many noise reduction techniques using microphone array, generalized sidelobe canceller (GSC) has been widely applied to reduce nonstationary noises. The performance of GSC is directly affected by its adaptation mode controller (AMC). That is, accurate target speech detection is essential to guarantee the sufficient noise reduction in pure noise intervals and the less distortion in target speech intervals. Thus, this paper proposes an improved AMC design technique in which the power ratio of the output of fixed beamforming to that of blocking matrix is calculated frequency bandwise and probabilistically modeled by mixture Gaussians for each class. Experimental results show that the proposed algorithm outperforms conventional AMCs in receiver operating curves (ROC) and output SNRs.

Neuroprotection of Recombinant Human Erythropoietin Via Modulation of N-methyl-D-aspartate Receptors in Neonatal Rats with Hypoxic-ischemic Brain Injury (신생 백서의 저산소성 허혈성 뇌손상에서 NMDA receptor 조절을 통한 유전자 재조합 인 에리스로포이에틴의 신경보호)

  • Jang, Yoon-Jung;Seo, Eok-Su;Kim, Woo-Taek
    • Neonatal Medicine
    • /
    • v.16 no.2
    • /
    • pp.221-233
    • /
    • 2009
  • Purpose: Erythropoietin (EPO) has neuroprotective effects in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma, and excitotoxicity. Current studies have demonstrated the neuroprotective effects of EPO, but limited data are available for the neonatal periods. Here in we investigated whether recombinant human EPO (rHuEPO) can protect the developing rat brain from HI injury via modulation of NMDA receptors. Methods: In an in vitro model, embryonic cortical neuronal cell cultures from Sprague-Dawley (SD) rats at 19-days gestation were established. The cultured cells were divided into five groups: normoxia (N), hypoxia (H), and 1, 10, and 100 IU/mL rHuEPO-treated (H+E1, H+ E10, and H+E100) groups. To estimate cell viability and growth, a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay was done. In an in vivo model, left carotid artery ligation was performed on 7-day-old SD rat pups. The animals were divided into six groups; normoxia control (NC), normoxia Sham-operated (NS), hypoxia-ischemia only (H), hypoxia-ischemia+vehicle (HV), hypoxia-ischemia+rHuEPO before a HI injury (HE-B), and hypoxia-ischemia+rHuEPO after a HI injury (HE-A). The morphologic changes following brain injuries were noted using hematoxylin and eosin (H/E) staining. Real-time PCR using primers of subunits of NMDA receptors (NR1, NR2A, NR2B, NR2C and NR2D) mRNA were performed. Results: Cell viability in the H group was decreased to less than 60% of that in the N group. In the H+E1 and H+E10 groups, cell viability was increased to >80% of the N group, but cell viability in the H+E100 group did not recover. The percentage of the left hemisphere area compared the to the right hemisphere area were 98.9% in the NC group, 99.1% in the NS group, 57.1% in the H group, 57.0% in the HV group, 87.6% in the HE-B group, and 91.6% in the HE-A group. Real-time PCR analysis of the expressions of subunits of NMDA receptors mRNAs in the in vitro and in vivo neonatal HI brain injuries generally revealed that the expression in the H group was decreased compared to the N group and the expressions in the rHuEPO-treated groups was increased compared to the H group. Conclusion: rHuEPO has neuroprotective property in perinatal HI brain injury via modulation of N-methyl-D-aspartate receptors.

Effect of Anode Thickness on the Overpotential in a Molten Carbonate Fuel Cell (용융탄산염형 연료전지에서 과전압에 미치는 전극두께의 영향)

  • Lee, Choong-Gon;Lee, Sung-Yoon;Ryu, Bo-Hyun;Kim, Do-Hyung;Lim, Hee-Chun
    • Journal of the Korean Electrochemical Society
    • /
    • v.13 no.1
    • /
    • pp.34-39
    • /
    • 2010
  • This work investigated the effect of anode thickness on the anodic overpotential with $100\;cm^2$ class MCFC single cells. The hydrogen oxidation rate in the molten carbonate is sufficiently high, which may lead to weak relation of overpotential with anode geometrical area. The relation of anode surface area and overpotential was analysed in terms of anode thickness in this work. Steady state polarization, inert gas step addition (ISA), and reactant gas addition (RA) methods were employed to the two cells with 0.77 mm and 0.36 mm thickness of anode. The result represented that the anodic overpotential at the cells were identical. It implied that the anodic overpotential was independent on the electrode thickness within the tested range.

Screening Method for Non-viable Seeds in Brassicaceae Vegetable Crops by Sinapine Leakage (Sinapine누출을 이용한 십자화과 채소의 퇴화종자 선별법)

  • 민태기
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.39 no.5
    • /
    • pp.473-479
    • /
    • 1994
  • A seed coating system was developed to screen non-viable seeds in the Brassicaceae. The crops studied were radish, chinese cabbage, broccoli, cauliflower and brussel sprout. Sinapine leaked more from artificially deteriorated seeds than non-deteriorated seeds. Seed coating with cellulose was to trap the sinapine leakage in the non-viable Brassicaceae vegetable seeds. The seeds were first hydrated, then coated with cellulose powder to capture the leakage. Coated seeds were dried, then sorted two fractions-fluorescent seeds and non-fluorescent seeds under the UV light. The ratio of the fluorescent seeds were higher in bad seedlot than good one. The germination rate were increased 3∼35% by eliminating the fluorescent seeds in tested Brassica vegetable seeds. Sowing non-fluorescent seeds resulted in a greater percent normal seedling than non-coated seeds in all seedlots. The fluorescent seeds contained a high percentage of the dead and abnormal seedlings.

  • PDF

Structure of Cholesteryl Pentyl Carbonate (Cholesteryl Pentyl Carbonate의 결정 및 분자구조)

  • Seo, Hye Ran;Park, Yeong Ja;B. M. Craven
    • Journal of the Korean Chemical Society
    • /
    • v.34 no.1
    • /
    • pp.29-36
    • /
    • 1990
  • Cholesteryl pentyl carbonate $(C_{33}H_{56}O_3)$ is monoclinic, space group P21, with a = 12.484(3), b = 9.043(3), c = 14.053(3)$\AA$, ${\beta} = 94.12(2)^{\circ}$ and z = 2. The intensity data were measured for the 2969 reflections within sin $\theta/\lambda = 0.52 {\AA}^{-1}$, using an automatic four--circle diffractometer and graphite monochromated Mo-K$\alpha$ radiation. The atomic coordinates from cholesteryl octanoate were used in an initial trial structure and the structure was refined by full-matrix least squares methods. The final R-factor was 0.12 for 1164 observed reflections. The pentyl group has shortened bond lengths due to the high thermal vibrations in this region. Adjacent molecules are related by $2_1$ screw axis so that they are arranged in an antiparallel array, corresponding to the Monolayer Type II packing mode. There are close packings of cholesteryl groups within the monolayers. This packing type is similar to those of cholesteryl hexanoate, octanoate, hexyl carbonate and oleate.

  • PDF