• Title/Summary/Keyword: 다공성막

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Pore Modification of Sol-Gel Driven Alumina Membrane via Soaking and Vapor-Deposition Method

  • 이상연;이승진;양승만;박승빈
    • Proceedings of the Membrane Society of Korea Conference
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    • 1995.04a
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    • pp.58-59
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    • 1995
  • 기체 분리용 무기분리막은 고분자막과 비교하여 열 및 구조적 안정성이 우수하므로, 석탄가스화반응 혼합기체중의 기체분리 등 고온 또는 고압공정에 적합한 분리방법으로서 주목되고 있다. 기체의 분리를 위한 무기재료막은 크게 다공성막과 비다공성막으로 나눌 수 있으며, 이 중 비기공 성막의 경우 높은 선택도를 가지나 투과도가 낮아 경제성이 떨어지는 것으로 평가되고 있다. 한편, 기존의 다공성막의 경우 투과도는 높으나 기체의 분리가 혼합기체중 각 기체의 분자량의 차이에 의존하는 Knudsen 확산에 제한되는 낮은 선택도를 갖는 단점이 있다. 따라서 다공성막의 기공을 특정기체의 선택도가 우수한 촉매물질등으로 개선하여 비기공성막에 비해 우수한 투과도를 갖고, 기공성막에 비해 향상된 선택도를 보이는 복합막의 연구가 활발히 추진되고 이\ulcorner. 본 연구는 솔젤법에 의해 제조된 팔라듐 함침 알루미나 지지막의 기공을 침투$\cdot$증착(Soaking and Vapor-deposition)법에 의해 개선하여 기체의 투과도를 높게 유지하면서 수소의 선택성을 향상시키는 것을 목적으로 하였다.

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Effect of Porous Membrane on Culture Properties of Blood-Brain Barrier Endothelial Cell (다공성막이 혈액뇌관문 내피세포의 배양에 끼치는 영향)

  • Lee, Keum-Jeong;Cho, Hye-Jin;Choi, Hyung-Taek;Na, O-Soon;Kim, Kyung-Yong
    • Applied Microscopy
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    • v.33 no.4
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    • pp.261-266
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    • 2003
  • The growth patterns of primary culture of bovine brain microvessel endothelial cells (BBMECs) were studied using electron microscopy when grown on $3.0{\mu}m$ and $0.4{\mu}m$ pore Transwell. The capillary fragments and isolated endothelial cells grew on collagen coated culture plate and Transwell membrane. The BBMECs grew only on the upper surface of membrane of $0.4{\mu}m$. But BBMECs on $3.0{\mu}m$ pore membrane migrated through the pore and grew on the opposite side of the membrane. In summary, BBMECs isolated by enzyme digestion could migrate through $3.0{\mu}m$ pore membrane but not through $0.4{\mu}m$ pore membrane. So $0.4{\mu}m$ pore membrane instead of $3{\mu}m$ pore membrane should be used for drug transport experiment or transendothelial electrical resistance measurement.

Controlled Release of Nifedipine from Osmotic Pellet Based on Porous Membrane (니페디핀을 포함한 삼투성펠렛의 제조와 다공성막을 통한 약물방출제어)

  • Youn, Ju-Yong;Ku, Jeong;Kim, Byung-Soo;Kim, Moon-Suk;Lee, Bong;Khang, Gil-Son;Lee, Hai-Bang
    • Polymer(Korea)
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    • v.32 no.4
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    • pp.328-333
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    • 2008
  • The osmotic delivery systems are based on osmosis. The transverse diffusion of water through a porous membrane from a medium with a low osmotic pressure to a medium with a high osmotic pressure. Nifedipine tablet dosage forms of Procardia $XL^{(R)}$(Pfizer) and $Adalat^{(R)}$(Bayer) are commercialized systems of this type that push-pull osmotic tablet operates successfully in delivering water-insoluble drugs. We prepared osmotic pellet system by fluidized bed coating method, and model-drug used nifedipine. The osmotic pellet system was composed of the core material. the swelling and osmotic pressure layer, the drug coating layer, and the porous membrane. This work is performed to investigate the effect of different factors, such as composition and thickness of membrane. The osmotic pellet has been successfully prepared by fluidized bed coating technology. The drug release behavior depended on the increase of CA ratio and thickness in porous membrane. The morphology of the osmotic pellet before and after the dissolution test were observed by SEM. In conclusion, we found that the drug release of osmotic pellet depended on the composition and coating thickness of porous membrane.

Controlled Release of Doxazosin in Multi-layered Pellet Using Polymer Blending (고분자 블렌딩을 이용하여 제조된 독사조신 다중층 펠렛의 약물방출제어)

  • Youn, Ju-Yong;Park, Sang-Wook;Lee, Soo-Young;Kim, Moon-Suk;Lee, Bong;Khang, Gil-Son;Lee, Hai-Bang
    • Polymer(Korea)
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    • v.32 no.4
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    • pp.322-327
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    • 2008
  • In this study, a multi-layered pellet was composed of a seed layer including a water-swellable agent and a drug layer containing doxazosin as a model drug, a porous membrane and a castor oil layer to control drug release. The pellet is prepared by a fluidized bed coating method. To confirm drug release from polymer blending in multi-layered pellet system, it is prepared by containing different ratio such as hydroxypropylmethylcellulose (HPMC) : ethyl cellulose (EC) in drug layer and cellulose acetate(CA) : Eudragit RS in membrane. Also, to confirm the effect of oil in drug release, castor oil is coated. As a result, we observed regularly spherical pellet with diameter of $1500{\mu}m$. Release pattern of drug is confirmed by dissolution tester in aqueous media. The more the ratio of EC in drug layer, CA in membrane, and castor oil layer in pellet, the less the drug release is observed. Formation and the amount of pores in membrane is observed by SEM.

Development of System for Measuring Evaporation Rate through Porous Medium in Fuel Cells (연료전지 다공성막을 통한 수분증발량의 정량적 측정에 관한 실험적 연구)

  • Kim, Jong-Rok;Kim, Moo-Hwan;Son, Sang-Young
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.6
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    • pp.579-582
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    • 2012
  • Removing residual water in a fuel cell is a critical operational process for managing its performance and controlling its lifetime. Understanding the mechanism of water transport in fuel cells is essential for the design of the water removal process. In this study, an experimental method for measuring the water evaporation rate through a gas diffusion layer, which is a porous medium, under steady-state conditions was developed. Experimental bench tests were conducted to apply the developed method. Then, the effects of various parameters of the drying gas and the gas diffusion layer were experimentally measured. The water evaporation rate increased as the humidity of the drying gas decreased and the flow rate of the drying gas increased. In addition, a thinner gas diffusion layer yielded a higher water evaporation rate.

미세 다공성 무기질 막에 의한 투과증발법

  • 이용택
    • Proceedings of the Membrane Society of Korea Conference
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    • 1996.03a
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    • pp.91-109
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    • 1996
  • 막에 의한 유기액체 혼합물을 분리 하는 방법으로 액/증기 계의 막투과 메카니즘으로 분리, 농축하는 투과증발법(Pervaporation)이 연구되어져 왔다. 이 방법은 공급상이 수용액, 투과상이 기체로써 상변화를 동반하는 과정이기 때문에 분리의 에너지 효율은 증류법에 비해 그다지 높게 기대 되지 않지만 공비점(azotropic point)을 가지는 혼합물이나 비점차가 적어 분해하기가 쉽고 증류법이 불가능한 혼합물의 분리에 많이 쓰여져 왔다. 그러나, 이 방법을 실용화 시키기 위해서는 분리계수 및 투과속도가 큰 막이 필요로 하며 현재 그 연구 개발에 박차를 가하고 있다. 본 강의는 무기재질을 가지는 다공성막을 사용하여 투과증발 분리법에 대한 최근의 연구 동향에 대해서 간략하게 서술하고자 한다.

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Preparation, Characterization and Gas Permeability of Asymmetric Porous Membranes of Poly(carbobenzoxyl-L-Lysin) (비대칭 다공성 폴리(카르보벤족시-L-리신)막의 제조, 평가 및 기체투과)

  • Kawai, Tohru;Lee, Young Moo;Fujita, Hiroshi
    • Membrane Journal
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    • v.6 no.2
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    • pp.96-100
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    • 1996
  • In order to improve the permeability of the homogenous membrane of poly(carbobenzoxy-L-lysin)(PCLL), which has very high selectivity of helium gas to nitrogen gas, asymmetric porous membranes of PCLL were prepared by casting from 20% solutions in dioxane and dimethylformamide(DMF), respectively. The membranes were characterized by measuring the number of the pores, the pore size distribution of the surface(the skin layer) and the thickness of the skin layer by scanning electron microscope and transmission electron microscope. The mean pore size and the pore density were lower for the membrane cast from dioxane than that from DMF, which was explained by the mechanism of the formation of the pores in the asymmetric porous membrane. The permeability coefficient observed could be roughly explained by the viscous flow through the skin layer. However, the selectivity observed was against the theory of the viscous flow.

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An Experimental Study of Membrane Transport in a Water-Ethanol System (물-에탄올 계에서 막투과 현상에 대한 실험적 연구)

  • 박원철;최창균
    • Proceedings of the Membrane Society of Korea Conference
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    • 1994.04a
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    • pp.43-44
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    • 1994
  • 일반적으로 다공성막을 사이에 두고 막을 통한 물질전달이 일어날 때 물질전달 속도는 압력차 $\Delta P$, 유속 V, 농도차 $\Delta C$ 등의 함수로 알려져 있다. 따라서 이들 여러 변수들 중에서 어느 한가지 변수만을 독립시키고 다른 변수들을 일정하게 고정시키면, 그 특정 변수가 물질전달 속도 J에 미치는 영향을 관찰할 수 있게 된다. 본 실험에서도 물과 에탄올 양쪽상의 유입 농도를 일정하게 유지시킴으로써 그 영향을 배재하고 유속과 압력차를 각각 독립시켜 그 영향을 살펴보았다.

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