• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.482-487
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• 2016

Ultra-violet rays are very harmful to eye health care. The blocking of ultra-violet rays and a reduction of optical reflection in the visible light range, which is to increase the share of transmitted light, and avoid the formation of ghost images in imaging, are important for the applications of polymer eyeglasses lenses. In this study, the high-refractive index polymer lenses, n=1.67, were fabricated by injection-molded method with the xylene diisocyanate monomer, 2,3-bis-1-propanethiol monomer, and benzotriazol UV absorber (SEESORB 709) mixture. To reduce the reflection of the polymer lens surfaces, multi-layer anti-reflection (AR) coatings were coated for both sides of the polymer lens using an E-beam evaporation system. The optical properties of the UV blocking polymer lens were characterized using a UV-visible spectrometer. The material properties of the thin films, which were composed AR coating layers, refractive index, and surface roughness, were analyzed by ellipsometry and atomic force microscopy. As a result, the fabricated polymer lens perfectly blocked ultra-violet rays below 395 nm with a blocking rate greater than 99%.

• Journal of Life Science
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• v.30 no.5
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• pp.434-442
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• 2020

In this study, Tenebrio molitor (brown mealworm) larvae powder was fermented with Saccharomyces cerevisiae M1 (KACC 93023). The fermented and non-fermented powders were subsequently administered to rats with induced non-alcoholic fatty liver disease to compare the degree of improvement. The rats exhibited abnormal lipid metabolism due to orotic acid, and the group that were fed the fermented larvae powder showed similar weight to normal rats. AST, ALT, ALP, and LDH activities, all known indicators of liver health, and various other lipid-related indicators appeared positive, suggesting improvement. The lipid peroxide and glutathione content in the liver tissue and serum were similar to or better than those of the normal group. Finally, morphological observations of liver tissue using H&E and oil red O stainings revealed that the fermented powder group showed markedly reduced fat along with normal hepatocyte shape and arrangement. To summarize, it was confirmed that dietary brown mealworm larvae improve non-alcoholic fatty liver function, and, when fermented with yeast, most indicators showed positive improvements to almost normal levels. As such, the fermented powder can be considered to improve non-alcoholic fatty liver, suggesting that it may be used as a material for various products in the future.

• Journal of Digital Convergence
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• v.12 no.2
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• pp.373-378
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• 2014

To investigate the wear status of contact lenses by analyzing care of contact lenses container and actual condition of people wearing contact lenses and in Gyeonggido. The results were based on a questionnaire survey of 200 people who are the students of the middle school, the high school and the college among the clients of opticians to purchase contact lenses for six months from January 2013 to July 2013. According to the poll, the highest number of those polled, 139 (55.16%) people, said they were wearing cosmetic color contact lenses. Female respondents and male respondents were in the proportion of 177 (88.5%) to 23 (11.5%), respectively. 37 people (18.5%) who responded said "yes" to the question of them sharing contact lenses and glasses. 103 people (51.5%) answered "no" to the question of regularly replacing their lens containers. 148 people (74%) answered "yes" to the question of having glasses in order to investigate contact lens wearers user rate of glasses. The highest number of respondents, 127 people (63.5%), said "middle school" was the first time that they wore contacts. Meanwhile, 65 people (43.92%) said they initiated wearing glasses at 4th-6th grades. It is considered that it is necessary using proper contact lenses suitable for the clients' eye health in order of vision correction, rather than for cosmetic purposes. The role of the optician is considered to be very important for the proper management of the appropriate contact lens hygiene and regular optical check-ups of the contact lens wearers.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1979.10a
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• pp.244.3-245
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• 1979

1. 수율계수 함수의 영향 : 유가 배양에 있어서 수율 계수가 제한 기질 농도의 함수일 경우에 대한 연구를 수행하였다. 사용한 수율 계수 함수는 기질 농도에 대하여 선형 함수였으며 목적함수는 중간 대사 물질의 생산량이었다. 1-가) 수율 계수 함수의 기울기가 음의 값으로 적어짐에 따라 제한 기질의 공급속도가 증가되었다. 1-나) 일반적으로 초기의 얼마 동안은 회분 배양에서와 같이 공급 속도가 거의 없었으며 그후 전환점 이후에 가서야 공급 속도가 증가하였다. 1-다) 전환점 이후에서도 처음에는 대부분의 경우에 공급속도가 음의 값으로 부터 시작하여 증가하기 시작하였다. 1-라) 어떤 경우에는 배양 초기부터 공급 속도가 양의 값으로부터 시작하였으나 곧 감소하였다가 다시 증가하는 비 단조형 변화를 보였다. 1-마) 전환점 이후에서 공급 속도가 증가하는 형태에서도 처음에는 선형 증가를 보이다가 나중에 지수적 증가를 보였다. 1-바) 위와 같은 공급 속도의 변화에 따른 발효조 내의 제한 기질 농도의 변화는 초기에는 가능한 최대치를 유지하다가 전환점 이후에는 갑자기 감소하는 형태를 취하였다. 2. 목적 함수의 영향: 목적 함수가 균체량과 생성 중간 대사물질 량의 선형 결합일 때 대하여 연구하였다. 선형 결합 계수로는 균체량과 생성대사 물질의 상대적인 값어치를 취하였다. 2-가) 허용 최대 균체 농도가 제한되어 있는 상황 하에서 생성 대사 물질의 상대적인 값이 증가 할수록 목적 함수가 증가하였다. 2-나)생성대사 물질의 상대적인 값이 증가할수록 전환점의 위치가 줄어들었다. 2-다) 생성대사 물질 상대적 값의 단위 증가에 대한 목적 함수는 균체량을 감안하지 않은 야마네박사의 결과에 수렴하였다. 2-라) 공급 속도는 상대 값이 커질수록 줄어들었다. 2-마) 균체량의 시간에 대한 곡선은 상대값이 증가할수록 감소하고 전형적인 분기점 형태의 변화를 보였다.변이 뚜렷하여 이로 인한 외임파강내의 염증성병변이 뚜렷이 나타나 있으며 와우관의 특히 기저회전에서의 유모세포의 손실이 심한 것으로 보아 중이염으로 인한 골도의 고음역에서의 손실이 발생함을 알 수 있다.A group), vinclozolin, procymidone, tetradifon cypermethrin, 그리고 fenvalerate(B group)에서는 70% 이상의 회수율을 얻었고, 20%의 ethyl acetate/hexane을 사용하여 분석한 경우는 5%나 10%의 ethyl acetate/hexane을 사용하여 분석했을 때보다 좋은 결과를 나타내어 전체 16종의 농약 중 14종에서 75% 이상의 회수율을 얻었으나, alachlor와 bifenthrin은 매우 낮은 회수율을 보여서 ethyl acetate와 hexane의 혼합용매가 이들 두 농약성분의 분석에는 적합하지 않은 용출 용매임을 알 수 있었다.NO_2의$ 급성 중독증상으로서는 눈, 코를 강하게 자극하고 폐충혈, 폐수종, 기관지염, 폐염 등을 일으킨다. 만성 중독시에는 만성폐섬유와 및 폐수종을 일으킨다. (4) $오존(O_3)$ Ozone은 자동차 배기가스에서 나오는 $NO_2$ gas 및 탄화수소와 작용하여, PAN이라는 자극성 물질을 생성시키는 광학적 Smog의 주요소로 알려져 있다. 자극적인 냄새가 있음으로 불쾌감을 주고 비, 인후점막의 전조감과 두통이 오며 폐기능을 저하시키며 더욱 진행되면 폐충혈, 폐수종 등을 일으킨다 (5) Smog에 의한 건강피해 대표적인 것이 1952.12.5~12.8까지 4일간 영국 Lon-don에서 계속된 Smog사건이며, 이 사건으로 말미암아 호흡기질환 사망율이 사건전보다 사건기간 중 혹은 사건후에 5~10배의 증가율을 보였다. 이때 Smog의 주원인은 연료의 불완전 연소에 의한 연기와 이때 발생

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.10
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• pp.4493-4501
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• 2011

This study was performed to determine the levels of MMSE-K among the elderly people affiliated with long-term care insurance services in rural areas, and to reveal its association with related variables. The interviews were performed, during the period from March 1st, to May 31th, 2009, to 410 elderlies in rural areas. As a results, The prevalence of cognitive functions among all subjects were 80.5% of severe cognitive impairment, 11.7% of mild cognitive impairment, and 7.8% of normal. The prevalence of cognitive functions were lower according to the higher grade of long-term care insurance. And the prevalence of cognitive functions were lower in the group of lower educational level, unemployed, live alone, lower monthly income, bear for living expenses by sons and daughters and medical aid, lower visual acuity, with urinary incontinence, with amnesia, without regular exercise and lower frequency of going out than their respective counterparts. The hierarchial multiple regression analysis was used to reveal the explanatory powers of factors influencing on the cognitive functions level. Such factors as age, bear for living expenses, visual acuity, urinary incontinence, amnesia, regular exercise and grade of long-term care services were significantly influenced with cognitive functions. especially the factors of health status were significantly influenced with cognitive functions.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.105-109
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• 2014

Purpose: To compare the change of visual acuity and NIBUT after watching smart-phone in 1 hour under low intensity of illumination. Methods: 50 subjects (male 22, female 28) aged 20's years old ($20.7{\pm}2.4$ years) who do not have eye disease and have a good eye condition were participated for this study. Objective refraction, corrected distance visual acuity and NIBUT were measured before and after watching smart-phone (Galaxy 2, Samsung, KOREA) under low intensity of illumination (0 lx.) Objective refraction was carried out using auto-chart project (CP-1000, Dongyang, Korea), phoropter (VT-20, Dongyang, Korea) and auto refractor-keratometer (MRK-3100, Huvitz, Korea). Results: Refractive error was changed from $-3.20{\pm}2.00$ D to $-3.38{\pm}2.00$ D (p=0.006) and corrected distance visual acuity was changed from $0.93{\pm}0.08$ to $0.91{\pm}0.10$ (p=0.000) and NIBUT was changed from $10.48{\pm}7.00$ seconds to $10.29{\pm}6.47$ seconds (p=0.761) before and after watching smart-phone under low intensity of illumination. Conclusions: Continuous watching smart-phone under low intensity of illumination lead to temporal change of distance visual acuity and suitable rest may reduce the influence of distance visual acuity and tear safety.

• Journal of Veterinary Clinics
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• v.23 no.2
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• pp.119-122
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• 2006

This study was performed to clarify the effect of oculo-acupuncture (OA) on change of serum gastrin concentration. Twenty-three clinically healthy mongrel dogs were used in this study. This study was comprised of two experiments. In experiment 1, the effect of OA (stomach/spleen region) with comparison of non-a cup oint was examined. On the other hand, the effect of OA (stomach/spleen region) with comparison by body acupuncture (BL-21) was also examined in experiment 2. Serum gastrin levels were measured on before, 0, 30, 60 and 120 minutes after treatment in both non-acupoint and stomach/spleen region groups, and BL-21 The results showed that significant decreases in serum gastrin level was detected on 30 mins(p<0.05) after OA when compared with that of non-acupoint group. Serum gastrin concentrations with OA at stomach/spleen region group were significantly decreased on 60 mins (p<0.05) and 120 mins (p<0.01) compared with those of the AP at BL21 group. In conclusion, it was demonstrated that OA at stomach/spleen region had significantly decreased serum gastrin levels in dogs and OA at stomach/spleen region decreased serum gastrin concentration more than that body acupuncture at BL-21.

• Journal of Life Science
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• v.24 no.1
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• pp.54-60
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• 2014

Aromatic hydrocarbons are toxic environmental pollutants that are detrimental to the ecosystem and human health. Among them, chlorotoluene and nitrotoluene are toxic to hydrobios and irritate the skin, eyes, and respiratory organs of humans. We herein report the development of recombinant microbial biosensors for cheap and rapid monitoring of chlorotoluene and nitrotoluene compounds. Plasmids were constructed by inserting the xylR regulatory gene for BTEX (benzene, toluene, ethylbenzene, and xylene) degradation into upstream of Po' (the DmpR activator promoter Po with the deletion of its own upstream activating sequences) or Pu (the cognate promoter of XylR)::lacZ (the ${\beta}$-galactosidase gene) and transformed into Escherichia coli $DH5{\alpha}$. In the presence of inducers, the biosensor cells immobilized in agarose developed a red color in 1-2 h due to the hydrolysis of chlorophenol red ${\beta}$-D-galactopyranoside (CPRG), a substrate of ${\beta}$-galactosidase that was expressed by the inducers. Among BTEX, high responses were specifically observed with o-, m-, p-chlorotoluene ($0.1{\mu}M-100 mM$) and o-, m-, p-nitrotoluene (0.1 mM-100 mM). Po' demonstrated higher responses than those with Pu. The biosensors immobilized in agarose showed good stability after 21 days' storage at $4^{\circ}C$, and responses in untreated wastewater spiked with chlorotoluene and nitrotoluene, suggesting they can be used to detect compounds in wastewater.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.4
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• pp.449-455
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• 2012

Purpose: This study was found the risk factors of cataract by gender in elder and older Korean adults. Methods: We investigated the data for 5,024 (men 2,163 people, women 2,861 people) people, aged 40-95 years, from the Korean National Health and Nutrition Examination Survey. We divided into two groups (group 1: 40-64 years, group 2: 65-94 years). We divided into two groups (group 1: 40-64 years, group 2: 65-94 years). Cataract was decided in case of at least one eye with lens opacity. We presented significant odds ratio (OR) increase of cataract according to the obesity and socioeconomic information including house income and education level after adjusting for diabetes, hypertension, high triglyceride, outside active, smoking and drinking habits in two groups with distinction of sex. Results: House income (or education) was strongly related to the prevalence of agerelated cataract in all groups. In models adjusting for all other related factors, cataract patients with lower income and education had a higher prevalence of cataract (group1: OR, 1.84[1.17-2.91], OR, 3.00[1.90-4.74], group 2: OR, 3.47[2.53-4.74], OR, 7.44[5.41-10.23] for men. In comparison, for women, cataract patients with lower income, lower education and obesity had a higher prevalence of cataract (group1: OR, 1.72[1.14-2.60], OR, 4.48[2.72-7.38], OR, 1.40[1.10-1.82], group 2: OR, 2.32[1.70-3.16], OR, 29.99[20.31-44.28], OR, 1.27[1.04-1.54]). Conclusions: Factors of low socioeconomic status were associated with age-related cataract in Korean. Obesity-cataract association was stronger in women.

• Journal of Convergence Society for SMB
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• v.3 no.2
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• pp.27-32
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• 2013

Wireless Body Area Networks (WBAN) have been made possible by the emergence of small and lightweight wireless systems such as Bluetooth, enabled devices and PDAs. Antennas are an essential part of any WBAN system and due to various technical requirements and physical constraints, careful consideration of their design and deployment is needed. This paper is proposing on the design of wearable antenna as parts of clothing to serve communications functions, such as tracking and navigation in health care applications. The substrates of the wearable antennas will be made from textile materials and since it is wearable, it should have a small size, be light weight, low maintenance, and unobtrusive. This proposed paper will also investigate the influence of different parameters for wearable antenna including types of textile/substrate to ensure that the antenna design satisfies WBAN requirements. The characteristics and behavior of the antenna need to adhere to specifications set by wireless standards and system technology requirements. This means that the transmitting and receiving frequency bands of the various units need to be chosen accordingly. Since there are restrictions on the level of power to which the human body can be exposed to, the antenna as well as other RF system components must be designed to meet these restrictions. Antenna gain, which directly affects power transmitted, is a critical parameter in ensuring power levels fall within the safety guidelines and so will be of primary importance in the design. The electromagnetic interaction between WBAN antennas and devices and the human body will also be explored.