• Journal of Digital Convergence
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• v.19 no.10
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• pp.357-365
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• 2021

This study is a descriptive survey research for identifing double mediating effect of ego-integrity and cultural competency and the moderated mediation effect of Wisdom on the relationship between basic pychological needs and successful aging. The participants were 211 elderly people aged at least 60 from June 2020 to March 2021. Data were collection by self-report questionnaire. Data was analyzed by Hayes' number 6 and 91 models using the SPSS/25.0 program and SPSS PROCESS MACRO. According to the study, the ego-integration and cultural competence were effected to double mediated in successful aging, and the ego-integration and cultural competence were effected to successful aging through moderated mediation by wisdom. Therefore, it is needed to develop welfare policy and strategy for the elderly to enhance ego-integration and cultural competence by effort to satisfy basic pychological needs and wisdom.

• 한국노년학
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• v.38 no.3
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• pp.521-536
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• 2018

The purpose of this study is examining the effect of aging attitudes of older people on their life satisfaction, and investigating the mediating role of solidarity between parents and children. To achieve this, the survey was conducted with 2,076 Korean elderlies who were sampled with proportional stratified, and performed multi-mediated regression with SPSS macro PROCESS v.2.16. The results are following. First, aging attitude that older people recognized significantly affects to their life satisfaction. Second, aging attitude significantly affects to the five sub-categories of solidarity between parents and children. Especially, as elderly shows more negative attitude on aging, the solidarity also goes higher. Third, among sub-categories of solidarity between parents and children, affectional, identical, and functional solidarities play roles of mediator on the relationship between aging attitude and life satisfaction, and affectional solidarity shows the biggest influence on the relationship. Based on the results, practical and policy intervention were suggested for better life satisfaction of Korean elderly.

• Journal of Food Hygiene and Safety
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• v.32 no.3
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• pp.243-248
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• 2017

Intracellular and extracellular oxidative stress initiated by reactive oxygen species (ROS) causes skin aging, which is characterized by wrinkles and atypical pigmentation. Use of antioxidant is an effective approach to prevent symptoms related to ROS-induced aging of the skin. Therefore, the antioxidant and anti-aging effect of Castanea crenata Siebold & Zucc. extracts (LCE) was investigated in this study. The LCE markedly reduced the hydrogen peroxide-induced cell damage, intracellular ROS, and oxidative stress-induced senescence in human dermal fibroblasts (HDFs). These results indicate that LCE might have beneficial effects on oxidative stress-induced damage and thus reduce skin aging.

• Journal of the Korean Applied Science and Technology
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• v.33 no.1
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• pp.13-22
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• 2016

This study set its purpose on to specify whether it is possible to use wheat sprout extracts for source of cosmetics, and its biological activity. Cellular experiment was conducted to apprehend toxicity of wheat sprout extracts and through study on the whitening and aging activity of skin cell. As a result, it is appeared that wheat sprout extracts have weak toxicity for HDF, B16F10 cells. Also, it is appeared that wheat sprout extracts have weak deterrent effect on melanin biosynthesis, but since the extracts impede expression of MMP-1, which is induced UV ray, the extracts hold down the aging effect by UV rays. Hence the extracts are effective on preventing wrinkles caused by UV ray and aging. Therefore, this study is expected to be utilized usefully, if the wheat sprout extracts are used as source of functional cosmetics from the perspective of preventing skin-aging in the future.

• Journal of Life Science
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• v.1 no.1
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• pp.15-23
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• 1991

노화현상에 관련된 가설은 프로그램설, 세포손상축적설 등 다양하나 증거와 연구자료가 아직은 불충분하고 미흡하다. 현재 상당한 주목을 받고 있고 또 일견 설득력이 있는 것으로 수용되고 있는 oxygen species에 의한 세포손상축적 가설은 시험관 또는 생체 내에서의 실험과 관측을 통해 연구에 상당한 진전이 있음에도 노화현상을 해석하는 또 다른 실마리에 불과하다. Oxygen radical이 세포내의 거대분자들 중 DNA에 손상과 변이를 일으키거나, 우리기를 수반하지 않는 다른 기작에 의해 조직손상이 일어나면서 세포내의 유리기반응에 이차적 장애가 유도되어 세포내의 분자들이 훼손되거나 변화됨으로서, 이들 손상물이 시간과 더불어 축적하여 신체기능의 퇴행을 수반한 질병과 노화현상이 나타나게 된다는 것이다. 유리기에 대한 효과를 가지는 SOD, catalase, glutathione, peroxidase, metal-chelator와 chain-breaking 효과를 가진 alpha-tocopherol, beta-carotere, urate, ascorbate, ubiquinone, glutathione, protein-thiol 등 항산화물질의 적용과 섭취의 중요성이 인식되었다.

• Proceedings of the KIEE Conference
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• 2006.07c
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• pp.1507-1508
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• 2006

XLPE 절연 전력케이블의 제조과정에서 발생하는 가교부산물을 제거할 목적으로 14주기노화를 실시하며, XLPE 절연체에 발생하는 수트리를 가속 발생 성장시킬 목적으로 가속수트리 열화를 실시한다. 22.9kV 트리억제형(TR CNCV-W) 케이블에 대하여 14주기노화 전과 후, 120, 240, 360일 가속수트리(AWTT) 후의 파괴전압을 분석하였다. 14주기노화는 상승효과와 감소효과가 비슷하게 작용하는 것으로 나타났으며, 240일 AWTT 이후에 노화가 가속되는 것으로 나타났다.

• Journal of Life Science
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• v.33 no.5
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• pp.414-421
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• 2023

Cnidium japonicum (C. japonicum) is a type of halophyte that inhabits soil of a high salinity, and according to previous studies, it is known to have antitumor effects. However, the skin's protective effect, particularly against UVB irradiation, has not been revealed. In this study, C. japonicum crude extract was studied to determine its effect on damage to human keratinocytes (HaCaT) induced by UVB irradiation, and ROS assays were performed, the results of which showed that C. japonicum crude extract affects UVB-induced photoaging damage in human keratinocytes. To examine inhibitory effects against the expressions of MMPs, RT-PCR and Western blot assay were performed by treating the crude extract at concentrations of 10, 50, and 100 ㎍/ml by irradiating UVB at 15 mJ/cm². As a result, it was confirmed that the mRNA and protein expression levels of MMP-1, MMP-3, and MMP-9 decreased in the group treated with C. japonicum crude extract, which also effectively regulated the antioxidant defense mechanism pathway by activating JNK, ERK, and p38. In conclusion, the current study suggested the possibility that C. japonicum could be used as a raw material for anti-photoaging cosmeceuticals in the future.

• The Journal of the Korea Contents Association
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• v.18 no.1
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• pp.117-131
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• 2018

The purpose of this study is to examine the effect of economic stress on aging anxiety focusing on the moderating effect of motivations for participation in volunteering, and age. In order to accomplish these purposes, a total of 182 elderly who have been volunteering were used for final analysis. The results from the multiple regression showed that economic stress increases aging anxiety among elderly and motivations for participation in volunteering are likely to mitigate aging anxiety. Also, aging anxiety is expected to be lower as people are older and have higher self-oriented motivation for volunteering. Based on the result, political and practical implications are discussed.

• Microbiology and Biotechnology Letters
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• v.35 no.4
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• pp.316-324
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• 2007

We studied the effects of genistein obtained from glycolysis of genistin, a kind of phytoestrogen present in soybeans, on cell proliferation and type I pN collagen synthesis in normal human dermal fibroblasts(NHDF). Cell proliferation was increased significantly with genistein treatment at 54-year aged NHDF. Genistein increased cell proliferation more strongly in cells form old doner than young doner. The senescence-associated ${\beta}$-galatosidase activity was decreased in NHDF from 77-year old doner with genistein treatment. Type I pN collagen synthesis was increased with genistein treatement in UVA treated and non-treated NHDF. The increasement of collagen synthesis was more effective in aged cells than young cells. Type I pN collagen synthesis was also increased with genistein treatment in collagen matrix culture with NHDF from sun-exposed and non-exposed skin from 54-year old doner. Genistein treatment inhibited MMP-1 synthesis in old NHDF but not in young NHDF. In conclusion, genistein may be a useful agent for preventing intrinsic aging as well as photoaging.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.4
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• pp.533-538
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• 2012

The retrogradation properties of a Korean rice cake ($Karedduk$) added with oligosaccharides after 0~30 hr of storage at $5^{\circ}C$ were examined by texture profile analysis and the Avrami equation using textural characteristics. Oligosaccharides, such as galactooligosaccharide (50%) and maltooligosaccharide, were added to dry rice flour at levels of 10%. In the amylogram, the breakdown (P-H) and consistency (C-H) of the Korean rice cake (Karedduk) added with oligosaccharides were lower than those of the control. Texture profile analysis using a Texture Analyzer revealed that the hardness of the Korean rice cake ($Karedduk$) added with oligosaccharides was lower than the control. The Avrami exponent ($n$) for the control, galactooligosaccharide (50%) 10% and maltooligosaccharide 10% addition was 2.415, 2.771 and 2.683, respectively. The time constant (1/$k$) for galactooligosaccharide (50%) 10% or maltooligosaccharide 10% addition was higher than the control. Overall, adding galactooligosaccharide (50%) 10% or maltooligosaccharide 10% to a Korean rice cake ($Karedduk$) is effective in retarding retrogradation.