• Title/Summary/Keyword: 노화현상

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Effects of Accelerated Thermal Aging on Dynamic Properties of Laminated Rubber Bearings (적층고무받침의 가속 열 노화 동적특성 영향)

  • Oh, Ju;Jung, Hie-Young
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.5A
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    • pp.417-424
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    • 2010
  • The dynamic properties of laminated rubber bearings used as isolators in structures could be significantly deteriorated because of the change of microstructure in rubber caused by thermal aging. As a result, a catastrophic failure of bridges and buildings unexpectedly occurs when they are subjected to earthquake attack. Here, the dynamic properties of laminated rubber bearings before and after different of compression-shear loading and repeated cycles loadings, ultimated failure test with thermal aging were first measured and compared to each other. The experimental results, the effects of thermal aging on the shear stiffness, energy absorption, and equivalent damping coefficient of laminated rubber bearings are investigated. It is found that the deterioration of dynamic properties of laminated rubber bearings caused by thermal aging is significant and should be taken into account in designing rubber bearings.

Approach of Antiaging Care in Cosmetics (항노화 화장품 연구 개발 동향)

  • Chang, Ih-Seop;Son, Ui-Dong;Hwang, Jae-Seong
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.3 s.52
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    • pp.213-218
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    • 2005
  • Recently, with the remarkable increase in elderly persons and improvement of skin care technique, the requirements of customer for anti-aging care have become very important. Also, after cosmeceutical-product law was done in 2001, the major interesting field in cosmetic industry has been focused to developing anti-aging materials having safety and efficacy by basic science. In this review, we ill introduce the trend of anti-aging research and materials to prevent wrinkle or improve elasticity of skin.

광노화의 탄력소의 변화

  • 이규석
    • Proceedings of the SCSK Conference
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    • 1996.07a
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    • pp.10-14
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    • 1996
  • 최근 오존층의 파괴로 인한 지구 자외선량의 증가로 피부암 및 광노화의 발생가능성이 증가되고있다. 광노화의 주요한 현상중의 하나는 탄력섬유상 물질이 축적되는 일광탄력 섬유증이다. 자외선은 탄력소 유전자의 전사과정증가를 유도하며 결국 비정상적인 탄력소의 증가를 유발한다는 보고가 있다. 본 연구에서는 피부 섬유아세포 및 각질형성세포를 배양하여 자외선이 탄력소 유전자발현에 미치는 영향 및 전사조절인자에 미치는 영향을 알아보고자 하였다. 피부섬유아세포에 UVB를 30mJ-200J/m 조사하여 nothern blotting한 결과 UV양이 증가함에 따라 탄력소 전사물이 증가되었고, 1001/$m^2$ 에서 최대의 증가를 보였다. 탄력소 promoter와 CAT을 접합시킨 pEP62 vector을 섬유아세포에 형질전환 시키고 UV에 의한 Promoter 활성을 본 결과 UV조사량이 증가할수록 활성이 증가되었고 200J/$m^2$ 에서 대조군에 비해 5배의 활성 증가를 보였다. 이 system에 광노화 억제물질로 알려진 retinoid를 5 $\times$ $10^{-6}$M처리하였을 때 UV에 의한 탄력소 promoter활성을 약 1/3로 감소시켰다. 각질 형성세포에서 UVB에 의한 transcription factor의 활성을 mobility shift assay에 의해 조사한 결과 AP-1 및 NFkB가 활성화됨을 볼 수 있었다.

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Factors Influencing Seniors' Behavioral Intention of Generative AI Services (시니어의 생성형AI 서비스 이용의도에 영향을 미치는 요인)

  • Sung, Myoung-cheol;Dong, Hak-rim
    • Journal of Venture Innovation
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    • v.7 no.2
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    • pp.41-56
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    • 2024
  • Recently, generative AI services, including ChatGPT, have garnered significant attention. These services appealed not only to digital natives, such as Generation Z, but also to digital immigrants, including seniors. This study aimed to analyze the factors affecting seniors' behavioral intention of generative AI services. A survey targeting seniors was conducted, resulting in 250 valid responses. The data were analyzed using multiple regression analysis. For this purpose, performance expectancy, effort expectancy, social influence, requisite knowledge, biophysical aging restrictions of seniors based on MATOA (Model for the Adoption of Technology by Older Adults), a research model on technology acceptance by seniors and AI hallucinations of generative AI services were set as independent variables. The empirical results were as follows: performance expectancy and social influence had a significant positive impact on seniors' behavioral intention of generative AI services. Additionally, requisite knowledge positively influenced seniors' behavioral intention of generative AI services, while biophysical aging restrictions had a significant negative effect. However, effort expectancy and AI hallucinations did not show a significant influence on seniors' behavioral intention of generative AI services. The variables were ranked by influence as follows: performance expectancy, social influence, requisite knowledge, and biophysical aging restrictions. Based on these research results, academic and practical implications were presented.

Aging of Immune System (면역 반응체계의 노화)

  • Chung, Kyung Tae
    • Journal of Life Science
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    • v.29 no.7
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    • pp.817-823
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    • 2019
  • Immune system provides defense integrity of body against external invaders. In order to accomplish the important defending role immune system is composed of many different components which are regenerated continuously during lifespan. The key components are professional killing cells such as macrophage, neutrophil, natural killer cell, and cytotoxic T cell and professional blocking molecule, antibody, which is produced by plasma cell, the terminal differentiated B cell. Immune response is orchestrated harmoniously by all these components mediated through antigen presenting cells such as dendritic cells. Immune responses can be divided into two ways: innate immune response and adaptive immune response depending on induction mechanism. Aging is a broad spectrum of physiological changes. Likewise other physiological changes, the immune components and responses are wane as aging is progressing. Immune responses become decline and dysregulating, which is called immunosenescense. Immune components of both innate and adaptive immune response are affected as aging progresses leading to increased vulnerability to infectious diseases. Numbers of immune cells and amounts of soluble immune factors were decreased in aged animal models and human and also functional and structural alterations in immune system were reduced and declined. Cellular intrinsic changes were discovered as well. Recent researches focusing on aging have been enormously growing. Many advanced tools were developed to bisect aging process in multi-directions including immune system area. This review will provide a broad overview of aging-associated changes of key components of immunity.

A Phenomenological Study on the Lived Experience of Aging of the Poor Elderly (빈곤노인의 노화경험에 대한 현상학적 연구)

  • Chang, Kyung-Eun
    • Korean Journal of Social Welfare
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    • v.61 no.4
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    • pp.355-380
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    • 2009
  • The purpose of this study is to explore the lived experience of aging of the poor elderly and to identify suitable welfare policies on their behalf. For this purpose, I selected 16 participants from the criterion sampling of the impoverished elderly and conducted in-depth interviews, after which the collected data was analyzed using the phenomenological approach of Cloaizzi(1978). As a result, 27 themes, 10 clusters of themes, and 4 categories were pinpointed. The 4 categories are 'Facing death,' 'Becoming despondent in heart and mind,' 'Living a hard life,' and 'Going with the flow of life.' By integrating the meanings of these findings, the essence of the lived experience of aging of the poor elderly was to be, 'Self-sufficiency despite receiving welfare benefits from the government.' The lived experience of aging of the poor elderly was revealed as not being entirely based around dependency but rather around strongly independent and positive life attitudes. But also found were difficulties due to lack of living expenses required for survival, deep death anxieties, and life attitudes in the context of Confucian culture. Based on the study results above, I presented welfare policies for the poor elderly as outlined: implementation of social activities in order to encourage independence and positivity among the poor elderly, actualization of payment that meets at least the minimum costs of living, consolidation of psychological-emotional assistance, implementation of death-related education programs, and the compilation of a welfare policy manual for the impoverished elderly.

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Power variation of Solar cell according to Electrolyte (전해질에 따른 Solar Cell의 출력 변화)

  • Shin, Jun-Oh;Jung, Tae-Hee;Kim, Tae-Bum;Won, Chang-Sub;Ji, Yang-Geun;Kong, Ji-Hyun;Kang, Gi-Hwan;Ahan, Hyung-Keun;Han, Deuk-Young
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.471-472
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    • 2009
  • 최근 태양전지의 내구성과 관련하여 모듈의 노화에 따른 효율 저하 현상이 대두되고 있다. 노화현상원인 중의 하나인 Hot spot 혹은 염분에 의한 백화현상으로 Solar Cell 과 EVA Sheet간 막들뜸 현상이 발생하며 그로 인한 공기 및 수분에 의해 금속 산화가 이뤄진다. 본 연구에서는 특히 전해질의 농도에 따른 금속의 산화와 그 출력에 대해 다룸으로써 태양광 발전 설치 지역 조건에 따른 Module의 내구성을 검토해 보았다. 산성비의 대부분을 구성하고 있는 황산과 질산의 PH를 0.1 간격으로 Split하여 농도의 변화에 의한 금속 부식과 그에 따른 전기적 저항 및 출력변화를 통해 태양광 Module 최적의 설치 지역조건을 제시하였다.

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The Aging Effect of $Avimid^(R)$ K3B/1M7 Laminates in $80^{\circ}C$ Water ($Avimid^(R)$ K3B/IM7 복합재료의 $80^{\circ}C$ 물에서의 노화현상)

  • Kim Hyung-Won
    • Journal of the Korean Society of Propulsion Engineers
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    • v.9 no.4
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    • pp.23-30
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    • 2005
  • The Hygrothermal aging of the laminates of $Avimid^(R)$ K3B/IM7 in $80^{\circ}C$ water was studied as a function of immersion time prior to forming microcracks. The factors causing the $80^{\circ}C$ water to degradation of the laminates could be the degradation of the matrix toughness, the change in residual stresses or the interfacial damage between the fiber and the matrix. The times to saturation in $80^{\circ}C$ water for the laminates and for the neat resin were 100 hours and 500 hours. After 500 hours aging of the neat resin, the glass transition temperature was changed less than 1% by DSC test, and the weight gain was 1.55% increase with the diffusion coefficient $7\times10^{-6}m/s^2$ and the fracture toughness was decreased about 41%. After 100 hours fully saturated aging of the ${[+45/0/-45/90]}_s$ K3B/IM7 laminates in $80^{\circ}C$ water, the weight gain was 0.41% increase with the diffusion coefficient $1\times10^{-6}m/s^2$. In 100 hours, the loss of the fracture toughness of the laminates was 43.8% of the original toughness by the microcracking fracture toughness criterion. Therefore, the main factor to degrade the microcracking toughness of the laminates could be the degradation of the matrix fracture toughness.

A New Attempt to Establish the Extrinsic Aging Hair Model to Evaluate The Response to Aging in Physical Property (모발 노화에 따른 물성변화와 외인성 노화모델의 개발)

  • Song, Sang-Hun;Choi, Wonkyung;Park, Hyunsub;Lim, Byung Tack;Park, Kyoung Ran;Kim, Younghyun;Park, Sujin;Son, Seong Kil;Lee, Sang-Min;Kang, Nae-Gyu
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.2
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    • pp.185-198
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    • 2019
  • Human tissue undergoes aging by the oxidant damage via structural change and its physical properties. The skin aging process is well known and many evaluations have been conducted. However, studies on hair aging were relatively few and thus care for aging hair is difficult. This study aims to fabricate an aging hair and identify anti-aging effect with known ingredient in anti-aging. First of all, physical properties of aging hair of age 60s by physiologically intrinsic factors were compared to those of the hair made by various extrinsic factors such as several chemical reactions and iteration numbers of the treatments. The extrinsic aging hair of this study relates to the less amount of lipid and to the hair of perm treated once accordingly, wherein several physical properties, preferably comprise roughness and tensile strength, present a novel concept of the intrinsic aging hair. The penetration of peptide into the aging hair was leading the extrinsic hair towards more structurally directed a younger hair. In addition to the structural change, the penetration of the peptide enhanced texture and tensile strength of the aging hair. These patterns have been also found in addition of propolis. For the first time, these qualitative studies exhibit that indeed our extrinsic aging hair well describes the anti-aging efficacy as a receptor for a cross-linker and the ingredients of human hair.